CoChat
Sign Up
Cited by 14

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Anticaries effect of an antioxidant-rich apple concentrate on enamel in an experimental biofilm-demineralization model

Giacaman, R.A., Contzen, M.P., Yuri, J.A., Muñoz-Sandoval, C.·2014·Journal of Applied Microbiology
DOI 10.1111/jam.12561
Open this paper in CoChat — free account

Abstract

Aims To assess the anticaries activity of an antioxidant-rich apple concentrate (ARAC) in an experimental biofilm caries model on enamel. Methods and results A validated caries model with Streptococcus mutans UA159 biofilms was used. Biofilms were formed on enamel slabs during 5 days. To mimic cariogenic challenges, triplicate slabs were exposed three times per day for 5 min to 10% sucrose followed by five additional minutes of exposure to serial dilutions of ARAC in 0·9% NaCl. A triplicate slab exposed to 10% sucrose followed by 0·9% NaCl served as caries-positive control. Acidogenicity was estimated by medium pH twice per day. After the experimental phase, biofilms were recovered to determine biomass, viable bacteria and intra- and extracellular polysaccharides. Slabs were used to estimate demineralization by the percentage of surface microhardness loss (%SHL). Differences among treatments were analysed by anova and Bonferroni test (P 0·05), the highest dilution of the apple concentrate induced significantly lower extracellular polysaccharide formation by the biofilm. Conclusions An apple concentrate in low concentrations appears to have a potential anticaries activity on enamel. Data suggest a metabolic rather than an antimicrobial mechanism, but further research is needed. Significance and impact of the study Phenolic compounds contained in apple concentrates seem to have anticaries properties that may be effective even in the presence of sucrose and in very low doses. Nu…

Overview

Integrity signals

Registry

Crossref · 10.1111/jam.12561

Cites

2 of 2 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • The use of surface hardness as an indicator of dentine mineral loss has been widely employed because there is a high correlation with transversal microradiography, which directly quantifies demineralization in dental enamel and also in dentine.

    “About the use of surface hardness as indicator of dentine mineral loss, it has been widely employed [25, 33, 34, 36, 39, 56–59] because there is a high correlation with transversal microradiography [25], which directly quantifies demineralization in dental enamel and also in dentine [60].”

    From Validation of a Cariogenic Biofilm Model to Evaluate the Effect of Fluoride on Enamel and Root Dentine Demineralization (2016) · cites this paper as [34]

  • This model was successfully used to evaluate the effect of iron on enamel and dietary products on either enamel or dentine demineralization.

    “This model was successfully used to evaluate the effect of iron on enamel [37] and dietary products on either enamel or dentine demineralization [34–36].”

    From Validation of a Cariogenic Biofilm Model to Evaluate the Effect of Fluoride on Enamel and Root Dentine Demineralization (2016) · cites this paper as [34]

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 39

  1. Aires, 2008, Effect of starch and sucrose on dental biofilm formation and on root dentine demineralization, Caries Res, 42, 380, 10.1159/000154783 · DOI · Paper page
  2. Bagramian, 2009, The global increase in dental caries. A pending public health crisis, Am J Dent, 22, 3
  3. Brighenti, 2008, Effect of Psidium cattleianum leaf extract on Streptococcus mutans viability, protein expression and acid production, Caries Res, 42, 148, 10.1159/000121439 · DOI
  4. Ccahuana-Vásquez, 2010, Streptococcus mutans biofilm model to evaluate antimicrobial substances and enamel demineralization, Braz Oral Res, 24, 135, 10.1590/S1806-83242010000200002 · DOI · Paper page
  5. Chu, 2007, Effect of compounds of Galla chinensis on remineralisation of initial enamel carious lesions in vitro, J Dent, 35, 383, 10.1016/j.jdent.2006.11.007 · DOI
  6. Coseteng, 1987, Changes in apple polyphenoloxidase and polyphenol concentrations in relation to degree of browning, J Food Sci, 52, 985, 10.1111/j.1365-2621.1987.tb14257.x · DOI
  7. Cury, 1997, In situ relationship between sucrose exposure and the composition of dental plaque, Caries Res, 31, 356, 10.1159/000262418 · DOI
  8. Cury, 2000, Biochemical composition and cariogenicity of dental plaque formed in the presence of sucrose or glucose and fructose, Caries Res, 34, 491, 10.1159/000016629 · DOI · Paper page
  9. Dauchet, 2006, Fruit and vegetable consumption and risk of coronary heart disease: a meta-analysis of cohort studies, J Nutr, 136, 2588, 10.1093/jn/136.10.2588 · DOI · Paper page
  10. Dubois, 1951, A colorimetric method for the determination of sugars, Nature, 168, 167, 10.1038/168167a0 · DOI · Paper page
  11. Ferrazzano, 2011, Plant polyphenols and their anti-cariogenic properties: a review, Molecules, 16, 1486, 10.3390/molecules16021486 · DOI
  12. Furiga, 2008, In vitro anti-bacterial and anti-adherence effects of natural polyphenolic compounds on oral bacteria, J Appl Microbiol, 105, 1470, 10.1111/j.1365-2672.2008.03882.x · DOI
  13. Giacaman, 2012, Effect of fluoridated milk on enamel and root dentin demineralization evaluated by a biofilm caries model, Caries Res, 46, 460, 10.1159/000339428 · DOI · Paper page
  14. Hirasawa, 2006, Inhibition of acid production in dental plaque bacteria by green tea catechins, Caries Res, 40, 265, 10.1159/000092236 · DOI
  15. Huang, 2002, High-throughput assay of oxygen radical absorbance capacity (ORAC) using a multichannel liquid handling system coupled with a microplate fluorescence reader in 96-well format, J Agric Food Chem, 50, 4437, 10.1021/jf0201529 · DOI
  16. Jeon, 2011, Natural products in caries research: current (limited) knowledge, challenges and future perspective, Caries Res, 45, 243, 10.1159/000327250 · DOI
  17. Jones, 2005, The effective use of fluorides in public health, Bull World Health Organ, 83, 670
  18. Koo, 2003, Inhibition of Streptococcus mutans biofilm accumulation and polysaccharide production by apigenin and tt-farnesol, J Antimicrob Chemother, 52, 782, 10.1093/jac/dkg449 · DOI · Paper page
  19. Lee, 2003, Major phenolics in apple and their contribution to the total antioxidant capacity, J Agric Food Chem, 51, 6516, 10.1021/jf034475w · DOI
  20. Liu, 2013, Health-promoting components of fruits and vegetables in the diet, Adv Nutr, 4, 384S, 10.3945/an.112.003517 · DOI · Paper page
  21. Lowry, 1951, Protein measurement with the Folin phenol reagent, J Biol Chem, 193, 265, 10.1016/S0021-9258(19)52451-6 · DOI
  22. Matsumoto, 2004, Inhibitory effects of cacao bean husk extract on plaque formation in vitro and in vivo, Eur J Oral Sci, 112, 249, 10.1111/j.1600-0722.2004.00134.x · DOI
  23. Murray, 2012, GBD 2010: a multi-investigator collaboration for global comparative descriptive epidemiology, Lancet, 380, 2055, 10.1016/S0140-6736(12)62134-5 · DOI
  24. Nakahara, 1993, Inhibitory effect of oolong tea polyphenols on glycosyltransferases of mutans Streptococci, Appl Environ Microbiol, 59, 968, 10.1128/AEM.59.4.968-973.1993 · DOI
  25. Paes Leme, 2006, The role of sucrose in cariogenic dental biofilm formation-new insight, J Dent Res, 85, 878, 10.1177/154405910608501002 · DOI · Paper page
  26. Petti, 2009, Polyphenols, oral health and disease: a review, J Dent, 37, 413, 10.1016/j.jdent.2009.02.003 · DOI
  27. Rethman, 2011, Nonfluoride caries-preventive agents Executive summary of evidence-based clinical recommendations, J Am Dent Assoc, 142, 1065, 10.14219/jada.archive.2011.0329 · DOI
  28. Scarpelli, 2013, Oral health-related quality of life among Brazilian preschool children, Community Dent Oral Epidemiol, 41, 336, 10.1111/cdoe.12022 · DOI
  29. Schilling, 1992, Glucans synthesized in situ in experimental salivary pellicle function as specific binding sites for Streptococcus mutans, Infect Immun, 60, 284, 10.1128/IAI.60.1.284-295.1992 · DOI
  30. Stookey, 2008, The effect of saliva on dental caries, J Am Dent Assoc, 139, 11S, 10.14219/jada.archive.2008.0347 · DOI
  31. Cate, 2012, Novel anticaries and remineralizing agents: prospects for the future, J Dent Res, 91, 813, 10.1177/0022034512455032 · DOI
  32. Thomas, 2007, Effect of ethylene oxide sterilization on enamel and dentin demineralization in vitro, J Dent, 35, 547, 10.1016/j.jdent.2007.03.002 · DOI
  33. Wu, 2004, Lipophilic and hydrophilic antioxidant capacities of common foods in the United States, J Agric Food Chem, 52, 4026, 10.1021/jf049696w · DOI
  34. Xie, 2008, In vitro remineralization effects of grape seed extract on artificial root caries, J Dent, 36, 900, 10.1016/j.jdent.2008.07.011 · DOI
  35. Yamanaka, 2004, Inhibitory effects of cranberry juice on attachment of oral streptococci and biofilm formation, Oral Microbiol Immunol, 19, 150, 10.1111/j.0902-0055.2004.00130.x · DOI
  36. Yanagida, 2000, Inhibitory effects of apple polyphenols and related compounds on cariogenic factors of mutans streptococci, J Agric Food Chem, 48, 5666, 10.1021/jf000363i · DOI
  37. Yoo, 2011, Antimicrobial traits of tea- and cranberry-derived polyphenols against Streptococcus mutans, Caries Res, 45, 327, 10.1159/000329181 · DOI
  38. Yuri, 2009, Antioxidant activity and total phenolics concentration in apple peel and flesh is determined by cultivar and agroclimatic growing regions in Chile, J Food Agric Environ, 7, 5
  39. Zero, 1995, In situ caries models, Adv Dent Res, 9, 214, 10.1177/08959374950090030501 · DOI

Cited by

Sorted by citations

Metadata

Authors
Giacaman, R. A., Contzen, M. P., Yuri, J. A., & Muñoz-Sandoval, C.
Affiliations
  • Cariology Unit; Department of Oral Rehabilitation; University of Talca; Talca Chile
  • Interdisciplinary Excellence Research Program on Healthy Aging (PIEI-ES); University of Talca; Talca Chile
Venue
Journal of Applied Microbiology
Publisher
Oxford University Press (OUP)
Published
2014-06-28
Volume
117
Issue
3
Pages
846-853
ISSN
1364-5072
DOI
10.1111/jam.12561
Cited by
14
References
2
Language
en
Licence
Funders
  • Chilean Government Grants
  • Fondecyt (11100005)
  • Fondef (AF0I1022)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review