Irisin reverses intestinal epithelial barrier dysfunction during intestinal injury via binding to the integrin αVβ5 receptor

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

Boström, P., Wu, J., Jedrychowski, M. P., Korde, A., Ye, L., Lo, J. C., Rasbach, K. A., Boström, E. A., Choi, J. H., Long, J. Z., et al. (2012) · Nature · doi:10.1038/nature10777 · Cited by 4,810 · see citing works

AMPK: guardian of metabolism and mitochondrial homeostasis

Herzig, S., & Shaw, R. J. (2017) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2017.95 · Cited by 4,094 · see citing works

Intestinal mucosal barrier function in health and disease

Turner, J. R. (2009) · Nature reviews. Immunology · doi:10.1038/nri2653 · Cited by 3,952 · see citing works

AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance

Garcia, D., & Shaw, R. J. (2017) · Molecular Cell · doi:10.1016/j.molcel.2017.05.032 · Cited by 1,997 · see citing works

Zonulin and its regulation of intestinal barrier function: the biological door to inflammation, autoimmunity, and cancer.

Fasano, A. (2011) · Physiological Reviews · doi:10.1152/physrev.00003.2008 · Cited by 979 · see citing works

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Kim, H., Wrann, C. D., Jedrychowski, M., Vidoni, S., Kitase, Y., Nagano, K., Zhou, C., Chou, J., Parkman, V.-J. A., Novick, S. J., et al. (2018) · Cell · doi:10.1016/j.cell.2018.10.025 · Cited by 638 · see citing works

ROS scavenging Mn 3 O 4 nanozymes for in vivo anti-inflammation

Yao, J., Cheng, Y., Zhou, M., Zhao, S., Lin, S., Wang, X., Wu, J., Li, S., & Wei, H. (2018) · Chemical Science · doi:10.1039/c7sc05476a · Cited by 636 · see citing works

Cell death and diseases related to oxidative stress: 4-hydroxynonenal (HNE) in the balance

Dalleau, S., Baradat, M., Guéraud, F., & Huc, L. (2013) · Cell Death & Differentiation · doi:10.1038/cdd.2013.138 · Cited by 580 · see citing works

Fibroblast growth factor 21 regulates energy metabolism by activating the AMPK–SIRT1–PGC-1α pathway

Chau, M. D. L., Gao, J., Yang, Q., Wu, Z., & Gromada, J. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1006962107 · Cited by 548 · see citing works

Uncoupling proteins and the control of mitochondrial reactive oxygen species production

Mailloux, R. J., & Harper, M. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.06.022 · Cited by 534 · see citing works

Structural and Functional Regulation of Tight Junctions by RhoA and Rac1 Small GTPases

Jou, T.-S., Schneeberger, E. E., & James Nelson, W. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.142.1.101 · Cited by 354 · see citing works

The Crosstalk between the Gut Microbiota and Mitochondria during Exercise

Clark, A. P., & Mach, N. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.00319 · Cited by 338 · see citing works

Irisin alleviates liver ischemia-reperfusion injury by inhibiting excessive mitochondrial fission, promoting mitochondrial biogenesis and decreasing oxidative stress

Bi, J., Zhang, J., Ren, Y., Du, Z., Li, Q., Wang, Y., Wei, S., Yang, L., Zhang, J., Liu, C., et al. (2018) · Redox Biology · doi:10.1016/j.redox.2018.10.019 · Cited by 288 · see citing works

Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin

Theodosiou, M., Widmaier, M., Böttcher, R. T., Rognoni, E., Veelders, M., Bharadwaj, M., Lambacher, A., Austen, K., Müller, D. J., Zent, R., et al. (2016) · eLife · doi:10.7554/elife.10130 · Cited by 279 · see citing works

Interplay among gut microbiota, intestinal mucosal barrier and enteric neuro-immune system: a common path to neurodegenerative diseases?

Pellegrini, C., Antonioli, L., Colucci, R., Blandizzi, C., & Fornai, M. (2018) · Acta Neuropathologica · doi:10.1007/s00401-018-1856-5 · Cited by 270 · see citing works

MerTK Cleavage on Resident Cardiac Macrophages Compromises Repair After Myocardial Ischemia Reperfusion Injury

DeBerge, M., Yeap, X. Y., Dehn, S., Zhang, S., Grigoryeva, L. S., Misener, S., Procissi, D., Zhou, X., Lee, D. C., Müller, W. A., et al. (2017) · Circulation Research · doi:10.1161/circresaha.117.311327 · Cited by 241 · see citing works

AMPK improves gut epithelial differentiation and barrier function via regulating Cdx2 expression

Sun, X., Yang, Q., Rogers, C. J., Du, ‬., & Zhu, M. J. (2017) · Cell Death and Differentiation · doi:10.1038/cdd.2017.14 · Cited by 233 · see citing works

Thyroid hormone (T ₃ ) stimulates brown adipose tissue activation via mitochondrial biogenesis and MTOR-mediated mitophagy

Yau, W. W., Singh, B. K., Lesmana, R., Zhou, J., Sinha, R. A., Wong, K. A., Wu, Y., Bay, B.-H., Sugii, S., Sun, L., et al. (2019) · Autophagy · doi:10.1080/15548627.2018.1511263 · Cited by 229 · see citing works

Irisin improves endothelial function in type 2 diabetes through reducing oxidative/nitrative stresses

Zhu, D., Wang, H., Zhang, J., Zhang, X., Xin, C., Zhang, F., Lee, Y., Zhang, L., Lian, K., Yan, W., et al. (2015) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2015.07.015 · Cited by 212 · see citing works

Irisin protects mitochondria function during pulmonary ischemia/reperfusion injury

Chen, K., Xu, Z., Liu, Y., Wang, Z., Li, Y., Xu, X., Chen, C., Xia, T., Liao, Q., Yao, Y., et al. (2017) · Science Translational Medicine · doi:10.1126/scitranslmed.aao6298 · Cited by 208 · see citing works

MicroRNA‐455 regulates brown adipogenesis via a novel HIF1an‐AMPK‐PGC1α signaling network

Zhang, H., Guan, M., Townsend, K. L., Huang, T. L., An, D., Yan, X., Xue, R., Schulz, T. J., Winnay, J. N., Mori, M. A., et al. (2015) · EMBO Reports · doi:10.15252/embr.201540837 · Cited by 150 · see citing works

Mast Cell Tryptase Reduces Junctional Adhesion Molecule-A (JAM-A) Expression in Intestinal Epithelial Cells: Implications for the Mechanisms of Barrier Dysfunction in Irritable Bowel Syndrome

Wilcz‐Villega, E., McClean, S., & OʼSullivan, M. (2013) · The American Journal of Gastroenterology · doi:10.1038/ajg.2013.92 · Cited by 135 · see citing works

Modulation of barrier function during Fas-mediated apoptosis in human intestinal epithelial cells

Abreu, M. T., Palladino, A., Arnold, E. T., Kwon, R. S., & McRoberts, J. A. (2000) · Gastroenterology · doi:10.1053/gast.2000.20232 · Cited by 131 · see citing works

Milk Fat Globule Epidermal Growth Factor 8 Attenuates Acute Lung Injury in Mice after Intestinal Ischemia and Reperfusion

Cui, T., Miksa, M., Wu, R., Komura, H., Zhou, M., Dong, W., Wang, Z., Higuchi, S., Chaung, W. W., Blau, S. A., et al. (2009) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200804-625oc · Cited by 124 · see citing works

Melatonin and mitochondrial function during ischemia/reperfusion injury

Ma, Z., Xin, Z., Di, W., Yan, X., Li, X., Reiter, R. J., & Yang, Y. (2017) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-017-2618-6 · Cited by 124 · see citing works

The association of microtubules with tight junctions is promoted by cingulin phosphorylation by AMPK

Yano, T., Matsui, T., Tamura, A., Uji, M., & Tsukita, S. (2013) · The Journal of Cell Biology · doi:10.1083/jcb.201304194 · Cited by 120 · see citing works

Intestinal fatty acid-binding protein and gut permeability responses to exercise

March, D. S., Marchbank, T., Playford, R. J., Jones, A. W., Thatcher, R., & Davison, G. (2017) · European Journal of Applied Physiology · doi:10.1007/s00421-017-3582-4 · Cited by 110 · see citing works

FNDC4 acts as an anti-inflammatory factor on macrophages and improves colitis in mice

Bosma, M., Gerling, M., Pasto, J., Georgiadi, A., Graham, E. L., Shilkova, O., Iwata, Y., Almer, S. H., Söderman, J., Toftgård, R., et al. (2016) · Nature Communications · doi:10.1038/ncomms11314 · Cited by 108 · see citing works

The significance of the gut barrier in disease: Figure 1

Meddings, J. B. (2008) · Gut · doi:10.1136/gut.2007.143172 · Cited by 105 · see citing works

Irisin/FNDC5--An updated review.

Panati, K., Suneetha, Y., & Narala, V. R. (2016) · PubMed · Cited by 91 · see citing works

Notch-1 Signaling Regulates Intestinal Epithelial Barrier Function, Through Interaction With CD4+ T Cells, in Mice and Humans

Dahan, S., Rabinowitz, K. M., Martin, A. P., Berin, M. C., Unkeless, J. C., & Mayer, L. (2010) · Gastroenterology · doi:10.1053/j.gastro.2010.10.057 · Cited by 83 · see citing works

Towards a three-dimensional framework of centrally regulated and goal-directed exercise behaviour: a narrative review

Venhorst, A., Micklewright, D. P., & Noakes, T. D. (2017) · British Journal of Sports Medicine · doi:10.1136/bjsports-2016-096907 · Cited by 83 · see citing works

Irisin and leptin concentrations in relation to obesity, and developing type 2 diabetes: A cross sectional and a prospective case-control study nested in the Normative Aging Study

Sahin-Efe, A., Upadhyay, J., Ko, B., Dincer, F., Park, K., Migdal, A. L., Vokonas, P., & Mantzoros, C. S. (2017) · Metabolism · doi:10.1016/j.metabol.2017.10.011 · Cited by 77 · see citing works

Circulating irisin levels are lower in patients with either stable coronary artery disease (CAD) or myocardial infarction (MI) versus healthy controls, whereas follistatin and activin A levels are higher and can discriminate MI from CAD with similar to CK-MB accuracy

Anastasilakis, A. D., Koulaxis, D., Kefala, N., Pοlyzos, S. A., Upadhyay, J., Pagkalidou, E., Economou, F. I., Anastasilakis, C. D., & Mantzoros, C. S. (2017) · Metabolism · doi:10.1016/j.metabol.2017.05.002 · Cited by 75 · see citing works

miR-381-3p knockdown improves intestinal epithelial proliferation and barrier function after intestinal ischemia/reperfusion injury by targeting nurr1

Liu, L., Yao, J., Li, Z., Zu, G., Feng, D., Yang, L., Qasim, W., Zhang, S., Li, T., Zeng, H., et al. (2018) · Cell Death and Disease · doi:10.1038/s41419-018-0450-z · Cited by 73 · see citing works

TRPM2 protects against tissue damage following oxidative stress and ischaemia–reperfusion

Miller, B. A., & Cheung, J. Y. (2015) · The Journal of Physiology · doi:10.1113/jp270934 · Cited by 63 · see citing works

Europium‐Doped Cerium Oxide Nanoparticles Limit Reactive Oxygen Species Formation and Ameliorate Intestinal Ischemia–Reperfusion Injury

Gubernatorova, E. O., Liu, X., Othman, A. A., Muraoka, W. T., Koroleva, E. P., Andreescu, S., & Tumanov, A. V. (2017) · Advanced Healthcare Materials · doi:10.1002/adhm.201700176 · Cited by 60 · see citing works

Inhibition of p66Shc-mediated mitochondrial apoptosis via targeting prolyl-isomerase Pin1 attenuates intestinal ischemia/reperfusion injury in rats

Feng, D., Yao, J., Wang, G., Li, Z., Zu, G., Li, Y., Luo, F., Ning, S., Qasim, W., Chen, Z., et al. (2017) · Clinical Science · doi:10.1042/cs20160799 · Cited by 59 · see citing works

Regulation of Enterocyte Apoptosis by Acyl-CoA Synthetase 5 Splicing

Gaßler, N., Roth, W., Funke, B., Schneider, A., Herzog, F., Tischendorf, J. J. W., Grund, K., Penzel, R., Bravo, I. G., Mariadason, J. M., et al. (2007) · Gastroenterology · doi:10.1053/j.gastro.2007.06.005 · Cited by 57 · see citing works

MyD88 adaptor-like (Mal) functions in the epithelial barrier and contributes to intestinal integrity via protein kinase C

Corr, S. C., Pålsson‐McDermott, E. M., Grishina, I., Barry, S. P., Aviello, G., Bernard, N. J., Casey, P. G., Ward, J. B. J., Keely, S. J., Dandekar, S., et al. (2013) · Mucosal Immunology · doi:10.1038/mi.2013.24 · Cited by 34 · see citing works

Delineating the relationships among the formation of reactive oxygen species, cell membrane instability and innate autoimmunity in intestinal reperfusion injury

Lee, H., Ko, E. H., Lai, M., Wei, N., Balroop, J., Kashem, Z., & Zhang, M. (2013) · Molecular Immunology · doi:10.1016/j.molimm.2013.11.012 · Cited by 33 · see citing works

Mechanisms Responsible for Vascular Hyporesponsiveness to Adrenomedullin after Hemorrhage

Wu, R., Cui, X., Dong, W., Zhou, M., Simms, H. H., & Wang, P. (2005) · Annals of Surgery · doi:10.1097/01.sla.0000167849.10599.30 · Cited by 19 · see citing works

Regulation of Intestinal Barrier Function by Microbial Metabolites

Ghosh, S., Whitley, C. S., Haribabu, B., & Jala, V. R. (2021) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2021.02.007 · Cited by 835 · see citing works

Progress and Challenges in the Biology of FNDC5 and Irisin

Maak, S., Norheim, F., Drevon, C. A., & Erickson, H. P. (2021) · Endocrine Reviews · doi:10.1210/endrev/bnab003 · Cited by 247 · see citing works

Irisin ameliorates neuroinflammation and neuronal apoptosis through integrin αVβ5/AMPK signaling pathway after intracerebral hemorrhage in mice

Wang, Y., Tian, M., Tan, J.-Y., Pei, X., Lu, C., Xin, Y., Deng, S.-X., Zhao, F., Gao, Y.-Q., & Gong, Y. (2022) · Journal of Neuroinflammation · doi:10.1186/s12974-022-02438-6 · Cited by 205 · see citing works

Role of irisin in physiology and pathology

Liu, S., Cui, F., Ning, K., Wang, Z., Fu, P., Wang, D., & Xu, H. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.962968 · Cited by 171 · see citing works

Serum irisin levels are decreased in patients with sepsis, and exogenous irisin suppresses ferroptosis in the liver of septic mice

Wei, S., Bi, J., Yang, L., Zhang, J., Wan, Y., Chen, X., Wang, Y., Wu, Z., Lv, Y., & Wu, R. (2020) · Clinical and Translational Medicine · doi:10.1002/ctm2.173 · Cited by 145 · see citing works

Involvement of GPX4 in irisin's protection against ischemia reperfusion‐induced acute kidney injury

Zhang, J., Bi, J., Ren, Y., Du, Z., Li, T., Wang, T., Zhang, L., Wang, M., Wei, S., Lv, Y., et al. (2020) · Journal of Cellular Physiology · doi:10.1002/jcp.29903 · Cited by 132 · see citing works

Irisin reduces inflammatory signaling pathways in inflammation-mediated metabolic syndrome

Slate‐Romano, J., Yano, N., & Zhao, T. C. (2022) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2022.111676 · Cited by 97 · see citing works

AMPK: The key to ischemia‐reperfusion injury

Cai, J., Chen, X., Liu, X., Li, Z., Shi, A., Tang, X., Xia, P., Zhang, J., & Yu, P. (2022) · Journal of Cellular Physiology · doi:10.1002/jcp.30875 · Cited by 84 · see citing works

Integrin-Ligand Interactions in Inflammation, Cancer, and Metabolic Disease: Insights Into the Multifaceted Roles of an Emerging Ligand Irisin

Park, E. J., Myint, P. K., Ito, A., Appiah, M. G., Darkwah, S. O., Kawamoto, E., & Shimaoka, M. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.588066 · Cited by 80 · see citing works

Irisin: A New Code Uncover the Relationship of Skeletal Muscle and Cardiovascular Health During Exercise

Ma, C., Ding, H., Deng, Y., Liu, H., Xiong, X., & Yang, Y. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.620608 · Cited by 75 · see citing works

The Emerging Role of Irisin in Cardiovascular Diseases

Fu, J., Li, F., Tang, Y., Cai, L., Zeng, C., Yang, Y., & Yang, J. (2021) · Journal of the American Heart Association · doi:10.1161/jaha.121.022453 · Cited by 72 · see citing works

Adipose–Muscle Crosstalk in Age-Related Metabolic Disorders: The Emerging Roles of Adipo-Myokines

Fang, P., She, Y., Yu, M., Min, W., Shang, W., & Zhang, Z. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2022.101829 · Cited by 62 · see citing works

The Role of Irisin in Cancer Disease

Pinkowska, A., Podhorska‐Okołów, M., Dzięgiel, P., & Nowińska, K. (2021) · Cells · doi:10.3390/cells10061479 · Cited by 61 · see citing works

Autophagy Dysregulation in Metabolic Associated Fatty Liver Disease: A New Therapeutic Target

Chen, C., & Lin, Y. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231710055 · Cited by 57 · see citing works

Irisin: An anti-inflammatory exerkine in aging and redox-mediated comorbidities

Trettel, C. D. S., Pelozin, B. R. D. A., Barros, M. P., Bachi, A. L. L., Braga, P. G. S., Momesso, C. M., Furtado, G. E., Valente, P. A., de Oliveira, E. M., Hogervorst, E., et al. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1106529 · Cited by 55 · see citing works

Irisin inhibits neutrophil extracellular traps formation and protects against acute pancreatitis in mice

Han, F., Ding, Z.-F., Shi, X., Zhu, Q., Shen, Q., Xu, X., Zhang, J., Gong, W., Xiao, W., Wang, D., et al. (2023) · Redox Biology · doi:10.1016/j.redox.2023.102787 · Cited by 54 · see citing works

Omentin-1 Modulates Macrophage Function via Integrin Receptors αvβ3 and αvβ5 and Reverses Plaque Vulnerability in Animal Models of Atherosclerosis

Lin, X., Sun, Y., Yang, S., Yu, M., Liu, P., Yang, J., Yang, J., Shao, Q., Liu, J., Liu, Y., et al. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.757926 · Cited by 52 · see citing works

Current Evidence of the Role of the Myokine Irisin in Cancer

Tsiani, E., Tsakiridis, N., Kouvelioti, R., Jaglanian, A., & Klentrou, P. (2021) · Cancers · doi:10.3390/cancers13112628 · Cited by 51 · see citing works

Modulatory Effect of Myokines on Reactive Oxygen Species in Ischemia/Reperfusion

Szabó, M. R., Pipicz, M., Csont, T., & Csonka, C. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21249382 · Cited by 45 · see citing works

Targeting AMPK signaling in ischemic/reperfusion injury: From molecular mechanism to pharmacological interventions

Paskeh, M. D. A., Asadi, A., Mirzaei, S., Hashemi, M., Entezari, M., Raesi, R., Hushmandi, K., Zarrabi, A., Ertaş, Y. N., Aref, A. R., et al. (2022) · Cellular Signalling · doi:10.1016/j.cellsig.2022.110323 · Cited by 41 · see citing works

Irisin, Exercise, and COVID-19

Alves, H. R., Lomba, G. S. B., Gonçalves-de-Albuquerque, C. F., & Burth, P. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.879066 · Cited by 39 · see citing works

Irisin at the crossroads of inter-organ communications: Challenge and implications

Zhao, R. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.989135 · Cited by 40 · see citing works

Potential Roles of Muscle-Derived Extracellular Vesicles in Remodeling Cellular Microenvironment: Proposed Implications of the Exercise-Induced Myokine, Irisin

Darkwah, S. O., Park, E. J., Myint, P. K., Ito, A., Appiah, M. G., Obeng, G., Kawamoto, E., & Shimaoka, M. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.634853 · Cited by 37 · see citing works

Irisin rescues diabetic cardiac microvascular injury via ERK1/2/Nrf2/HO-1 mediated inhibition of oxidative stress

Zhu, D., Zhang, X., Wang, F., Ye, Q., Yang, C., & Liu, D. (2021) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2021.109170 · Cited by 36 · see citing works

The Role of Adipokines and Myokines in the Pathogenesis of Different Obesity Phenotypes—New Perspectives

Pelczyńska, M., Miller‐Kasprzak, E., Piątkowski, M., Mazurek, R., Klause, M., Suchecka, A., Bucoń, M., & Bogdański, P. (2023) · Antioxidants · doi:10.3390/antiox12122046 · Cited by 31 · see citing works

Irisin and Energy Metabolism and the Role of Irisin on Metabolic Syndrome

Aladag, T., Moğulkoç, R., & Baltacı, A. K. (2023) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/1389557523666230411105506 · Cited by 30 · see citing works

Irisin/BDNF signaling in the muscle-brain axis and circadian system: A review

Inyushkin, A. N., Полетаев, В., Михайловна, И. Е., Сергеевич, К. И., & Inyushkin, A. A. (2023) · Journal of Biomedical Research · doi:10.7555/jbr.37.20230133 · Cited by 30 · see citing works

Targeting AMPK with Irisin: Implications for metabolic disorders, cardiovascular health, and inflammatory conditions — A systematic review

Laurindo, L. F., Rodrigues, V. D., Laurindo, L. F., Cherain, L. M. A., de Lima, E. P., Boaro, B. L., Oliveira, J. D. S. C., Chagas, E. F. B., Catharin, V. C. S., Haber, J. F. D. S., et al. (2024) · Life Sciences · doi:10.1016/j.lfs.2024.123230 · Cited by 31 · see citing works

Neuroprotective Effects of Exogenous Irisin in Kainic Acid-Induced Status Epilepticus

Cheng, Y., Cui, Y., Zhai, Y., Xin, W., Yu, Y. P., Liang, J., Li, S., & Sun, H. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.738533 · Cited by 29 · see citing works

Exercise-induced irisin ameliorates cognitive impairment following chronic cerebral hypoperfusion by suppressing neuroinflammation and hippocampal neuronal apoptosis

Xiao, W., Yang, Y., Bai, L., Yang, P., Li, R., Yang, D., Li, F., Quan, L., Liang, Q., Yan, Y., et al. (2025) · Journal of Neuroinflammation · doi:10.1186/s12974-025-03493-5 · Cited by 30 · see citing works

Treadmill Exercise Alleviates Cognition Disorder by Activating the FNDC5: Dual Role of Integrin αV/β5 in Parkinson’s Disease

Tang, C., Liu, M., Zhou, Z., Li, H., Yang, C., Yang, L., & Xiang, J. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24097830 · Cited by 27 · see citing works

Irisin attenuates acute glaucoma-induced neuroinflammation by activating microglia-integrin αVβ5/AMPK and promoting autophagy

Zhang, Q., Xiang, S., Chen, X., Rong, Y., Huang, L., Chen, Z., Yao, K., Chen, W., Deng, C., & Wang, J. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.112545 · Cited by 26 · see citing works

Vaccarin enhances intestinal barrier function in type 2 diabetic mice

Sun, J., Yu, X., Hou, B., Ai, M., Qi, M., Ma, X., Cai, M.-J., Gao, M., Cai, W.-W., Ni, L., et al. (2021) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2021.174375 · Cited by 22 · see citing works

Irisin ameliorates myocardial ischemia-reperfusion injury by modulating gut microbiota and intestinal permeability in rats

Liu, Q., Zhu, Y., Li, G., Guo, T., Jin, M., Xi, D., Wang, S., Liu, X., Guo, S., Liu, H., et al. (2023) · PLoS ONE · doi:10.1371/journal.pone.0291022 · Cited by 22 · see citing works

Role and Functions of Irisin: A Perspective on Recent Developments and Neurodegenerative Diseases

Minuti, A., Raffaele, I., Scuruchi, M., Lui, M., Muscarà, C., & Calabrò, M. (2025) · Antioxidants · doi:10.3390/antiox14050554 · Cited by 24 · see citing works

Irisin alleviates CFA-induced inflammatory pain by modulating macrophage polarization and spinal glial cell activation

Rahman, M. M., Hwang, S.-M., Go, E. J., Kim, Y. H., & Park, C. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.117157 · Cited by 20 · see citing works

Unlocking the Therapeutic Potential of Irisin: Harnessing Its Function in Degenerative Disorders and Tissue Regeneration

Zhang, Y., Wang, L., Kang, H., Lin, C.-Y. J., & Fan, Y. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24076551 · Cited by 20 · see citing works

Circulating sepsis-related metabolite sphinganine could protect against intestinal damage during sepsis

Wang, Z., Yue, Q., Wang, F., Zhang, B., & Jianguo, T. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1151728 · Cited by 20 · see citing works

Exercise ameliorating myocardial injury in type 2 diabetic rats by inhibiting excessive mitochondrial fission involving increased irisin expression and AMP‐activated protein kinase phosphorylation

Wang, B., Chen, Z., Wang, Y., Tian, X., Lin, J., Zhu, B., Zhou, Y., Zhang, X., Li, N., Sun, Y., et al. (2023) · Journal of Diabetes · doi:10.1111/1753-0407.13475 · Cited by 20 · see citing works

Bryostatin‐1 attenuates intestinal ischemia/reperfusion‐induced intestinal barrier dysfunction, inflammation, and oxidative stress via activation of Nrf2/HO‐1 signaling

Liu, M., Wen, H., Zuo, L., Song, X., Geng, Z., Ge, S., Ge, Y., Wu, R., Chen, S., Yu, C., et al. (2023) · The FASEB Journal · doi:10.1096/fj.202201540r · Cited by 19 · see citing works

Salidroside Ameliorates Furan-Induced Testicular Inflammation in Relation to the Gut-Testis Axis and Intestinal Apoptosis

Wang, Z., Li, L., Yan, H., Li, W., Pang, Y., & Yuan, Y. (2023) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.3c06587 · Cited by 19 · see citing works

Integrin αV Mediates the Effects of Irisin on Human Mature Adipocytes

Fu, T., Li, C., Sun, Z., Yan, B., Wu, Y., Huang, Z., & Yin, X. L. (2022) · Obesity Facts · doi:10.1159/000523871 · Cited by 19 · see citing works

Molecular Basis of Irisin Regulating the Effects of Exercise on Insulin Resistance

Lin, J., Liu, X., Zhou, Y., Zhu, B., Wang, Y., Cui, W., Peng, Y., Wang, B., Chen, Z., & Zhao, R. (2022) · Applied Sciences · doi:10.3390/app12125837 · Cited by 18 · see citing works

Irisin prevents hypoxic-ischemic brain damage in rats by inhibiting oxidative stress and protecting the blood-brain barrier

Xu, X., Zhou, R., Ying, J., Li, X., Lu, R., Qu, Y., & Mu, D. (2023) · Peptides · doi:10.1016/j.peptides.2023.170945 · Cited by 18 · see citing works

Remifentanil Promotes PDIA3 Expression by Activating p38MAPK to Inhibit Intestinal Ischemia/Reperfusion-Induced Oxidative and Endoplasmic Reticulum Stress

Shen, J., Zhan, Y., He, Q., Deng, Q., Li, K., Wen, S., & Huang, W. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.818513 · Cited by 18 · see citing works

Irisin is an Effector Molecule in Exercise Rehabilitation Following Myocardial Infarction (Review)

Qin, S., Tian, Z., Boidin, M., Buckley, B. J. R., Thijssen, D. H. J., & Lip, G. Y. H. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.935772 · Cited by 17 · see citing works

Hydrogen-rich saline protects intestinal epithelial tight junction barrier in rats with intestinal ischemia–reperfusion injury by inhibiting endoplasmic reticulum stress-induced apoptosis pathway

Jiang, S., Fan, Q., Xu, M. Q., Cheng, F., Li, Z., Ding, G., Geng, L., & Fu, T. (2020) · Journal of Pediatric Surgery · doi:10.1016/j.jpedsurg.2020.01.061 · Cited by 17 · see citing works

Irisin in atherosclerosis

Cheng, Z.-B., Huang, L., Xiao, X., Sun, J.-X., Zou, Z.-K., Jiang, J.-F., Lu, C., Zhang, H.-Y., & Zhang, C. (2021) · Clinica Chimica Acta · doi:10.1016/j.cca.2021.08.022 · Cited by 17 · see citing works

Irisin: A Promising Target for Ischemia‐Reperfusion Injury Therapy

Wang, Y., Liu, H., Sun, N., Li, J., Peng, X., Jia, Y., Karch, J. M., Yu, B., Wehrens, X. H. T., & Tian, J. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/5391706 · Cited by 16 · see citing works

Involvement of kindlin‐2 in irisin’s protection against ischaemia reperfusion‐induced liver injury in high‐fat diet‐fed mice

Jia, Z., Ren, Y., Bi, J., Wang, M., Zhang, L., Wang, T., Wei, S., Mou, X., Lv, Y., & Wu, R. (2020) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.15910 · Cited by 15 · see citing works

Irisin promotes intestinal epithelial cell proliferation via Wnt/β-catenin and focal adhesion kinase signaling pathways

Gaowa, A., Leangpanich, S., Park, E. J., Kawamoto, E., & Shimaoka, M. (2024) · Scientific Reports · doi:10.1038/s41598-024-76658-6 · Cited by 14 · see citing works

The Role of the Myokine Irisin in the Protection and Carcinogenesis of the Gastrointestinal Tract

Pinkas, M., & Brzozowski, T. (2024) · Antioxidants · doi:10.3390/antiox13040413 · Cited by 12 · see citing works

The potential role of FNDC5/irisin in various liver diseases: awakening the sleeping beauties

Wang, X., Mao, L., Li, C., Hui, Y., Yu, Z., Sun, M., Li, Y., Guo, G., Yang, W., Cui, B., et al. (2022) · Expert Reviews in Molecular Medicine · doi:10.1017/erm.2022.19 · Cited by 12 · see citing works

Irisin improves acute kidney injury induced by ischemia-reperfusion through targeting energy metabolism reprogramming

Zhao, L., Zhang, T., Zhao, Z., Ren, X., Huang, X. Q., Hao, Y., & Zhou, X. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.147073 · Cited by 11 · see citing works

Inhibition of integrin alpha v/beta 5 mitigates the protective effect induced by irisin in hemorrhage

Wang, L., Kulthinee, S., Slate‐Romano, J., Zhao, T., Shanmugam, H., Dubielecka, P. M., Zhang, L. X., Qin, G., Zhuang, S., Chin, Y. E., et al. (2023) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2023.104869 · Cited by 11 · see citing works

Inhibition of platelet activation suppresses reactive enteric glia and mitigates intestinal barrier dysfunction during sepsis

Cheng, B., Du, M., He, S., Yang, L., Wang, X., Gao, H., Chang, H., Gao, W., Li, Y., Wang, Q., et al. (2022) · Molecular Medicine · doi:10.1186/s10020-022-00556-8 · Cited by 11 · see citing works

Potential role of irisin in digestive system diseases

Zhang, Y., Zhao, L., Gao, H., Zhai, J., & Song, Y. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115347 · Cited by 10 · see citing works

SLC25 family with energy metabolism and immunity in malignant tumors

Zhang, G., Wang, N., Ma, S., Wei, Z., Tao, P., & Cai, H. (2023) · ONCOLOGIE · doi:10.1515/oncologie-2023-0280 · Cited by 9 · see citing works

Irisin Ameliorate Acute Pancreatitis and Acinar Cell Viability through Modulation of the Unfolded Protein Response (UPR) and PPARγ-PGC1α-FNDC5 Pathways

Horwitz, A., & Birk, R. Z. (2024) · Biomolecules · doi:10.3390/biom14060643 · Cited by 9 · see citing works

Irisin prevents visceral hypersensitivity and colonic hyperpermeability in a rat model of irritable bowel syndrome

Nozu, T., Miyagishi, S., Ishioh, M., Takakusaki, K., & Okumura, T. (2025) · Peptides · doi:10.1016/j.peptides.2025.171394 · Cited by 9 · see citing works

Irisin regulates integrin αvβ5/FAK/ERK to inhibit neutrophil extracellular traps formation and reduce pancreatic beta-cells pyroptosis in type 2 diabetes mellitus

Tan, A., Li, T., Yang, J., Li, X., Li, W., & Yu, J. (2025) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-025-01852-z · Cited by 9 · see citing works

Irisin Association with Ki-67, MCM3 and MT-I/II in Squamous Cell Carcinomas of the Larynx

Pinkowska, A., Nowińska, K., Ciesielska, U., & Podhorska‐Okołów, M. (2021) · Biomolecules · doi:10.3390/biom12010052 · Cited by 9 · see citing works

Irisin: A Potentially Fresh Insight into the Molecular Mechanisms Underlying Vascular Aging

Wang, Y., Wang, M., & Wang, Y. (2023) · Aging and Disease · doi:10.14336/ad.2023.1112 · Cited by 10 · see citing works

Fenpropathrin increases gliquidone absorption via causing damage to the integrity of intestinal barrier

Xu, L., Shen, W. H., Liu, Y., Zhang, M., Yang, Y., & Yin, D. (2022) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2022.113882 · Cited by 9 · see citing works

Phenolic Acids from Fructus Chebulae Immaturus Alleviate Intestinal Ischemia-Reperfusion Injury in Mice through the PPARα/NF-κB Pathway

Liu, J., Li, B., Li, B., Qiu, F., Diao, Y., Lei, Y., Liu, J., & Zhang, W. (2022) · Molecules · doi:10.3390/molecules27165227 · Cited by 9 · see citing works

Calycosin Improves Intestinal Mucosal Barrier Function after Gastrectomy in Rats through Alleviating Bacterial Translocation, Inflammation, and Oxidative Stress

Peng, H., Jin, L., Zhang, Q., Shen, Y., Wang, Z., Zhou, F., & Yu, Q. (2022) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2022/7412331 · Cited by 8 · see citing works

Irisin inhibits CCK-8-induced TNF-α production via integrin αVβ5-NF-κB signaling pathways in Nile tilapia (Oreochromis niloticus)

Deng, W., Cao, Z., Dong, R., Yan, Y., & Jiang, Q. (2023) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2023.109245 · Cited by 8 · see citing works

The emerging roles of irisin in vascular calcification

Wang, S., Hu, S., & Pan, Y. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1337995 · Cited by 8 · see citing works

Irisin as an emerging target in the regulation of reproductive functions in health and disease

Nalla, S. V., Jayapradha, P., Lalruatmawii, Nandheeswari, K., Naxine, P., Vigneshwaran, G., Rohilla, G., Dubey, I., & Kushwaha, S. (2024) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2024.114529 · Cited by 8 · see citing works

Potential role of integrin αV as irisin receptor and advances in research

Bai, Z., Chen, Z., Sun, T., Ma, C., & Meng, A. (2025) · Peptides · doi:10.1016/j.peptides.2025.171439 · Cited by 7 · see citing works

Recent insights into the effect of endoplasmic reticulum stress in the pathophysiology of intestinal ischaemia‒reperfusion injury

Zhang, J., Zhang, X., Liu, Y., Shi, Y., Chen, F., & Leng, Y. (2024) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2024.149612 · Cited by 7 · see citing works

Impact of menopause-associated frailty on traumatic brain injury

Sinder, S. B., Sharma, S. V., Shirvaikar, I. S., Pradhyumnan, H., Patel, S. H., Diaz, I. C., Perez, G. G., Bramlett, H. M., & Raval, A. P. (2024) · Neurochemistry International · doi:10.1016/j.neuint.2024.105741 · Cited by 7 · see citing works

Intracerebroventricular administration of the exercise hormone irisin or acute strenuous exercise alleviates epileptic seizure-induced neuroinflammation and improves memory dysfunction in rats

Kumral, Z. N. Ö., Akgün, T., Haşim, C., Ulusoy, E., Kalpakçıoğlu, M. K., Yüksel, M. F., Okumuş, T., Us, Z., Akakın, D., Yüksel, M., et al. (2024) · BMC Neuroscience · doi:10.1186/s12868-024-00884-x · Cited by 6 · see citing works

MicroRNA dynamics in irisin-mediated signaling pathways within adipose tissue

Ho, M.-Y., Chiu, K.-P., Tsai, M., Yeh, J., Huang, Y., Li, Y., Wang, H., Hsieh, C., Wen, M., & Wang, C. (2024) · Journal of Biosciences · doi:10.1007/s12038-024-00475-2 · Cited by 5 · see citing works

Irisin inhibits PCSK9 expression through activating AMPK-SREBP2 pathway

Xu, R., Liu, Q., Ma, X., & Hou, J. (2022) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2022.09.034 · Cited by 5 · see citing works

Inhibition of platelet activation suppresses reactive enteric glia and mitigates intestinal barrier dysfunction during sepsis

Cheng, B., Du, M., He, S., Yang, L., Wang, X., Gao, H., Chang, H., Gao, W., Li, Y., Wang, Q., et al. (2022) · Molecular Medicine · doi:10.1186/s10020-022-00562-w · Cited by 5 · see citing works

Effects of irisin on ovariectomy-induced depression, anxiety, and bodyweight growth in female mice

Xie, X., Zhang, Y., & He, J. (2025) · Peptides · doi:10.1016/j.peptides.2025.171349 · Cited by 4 · see citing works

Inhibition of miR-142-3p promotes intestinal epithelial proliferation and barrier function after ischemia/reperfusion injury by targeting FoxM1

Wang, Y., Jia, Z., Zheng, M., Wang, P., Gao, J., Zhang, X., Zhou, T., & Zu, G. (2024) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-024-05038-5 · Cited by 3 · see citing works

The Effect of Hypoxia on Irisin Expression in HL-1 Cardiomyocytes

Grzeszczuk, M., Mrozowska, M., Kmiecik, A. M., Rusak, A., Jabłońska, K., Ciesielska, U., Dzięgiel, P., & Nowińska, K. (2024) · In Vivo · doi:10.21873/invivo.13675 · Cited by 3 · see citing works

Irisin in ischemic stroke, Alzheimer’s disease and depression: a Narrative Review

Zhang, Q., Zhang, L., Zhao, N., & Li, Y. (2024) · Brain Research · doi:10.1016/j.brainres.2024.149192 · Cited by 2 · see citing works

Effect of the Myokine Irisin on Circadian Rhythm of Voluntary Locomotor Activity in Rats

Inyushkin, A. N., Павленко, С. И., Isakova, T. S., Konashenkova, A., Inyushkin, A. A., & Inyushkin, A. A. (2025) · Journal of Evolutionary Biochemistry and Physiology · doi:10.1134/s0022093025020164 · Cited by 2 · see citing works

Metabolic activity of immunocompetent cells in assessment of individual cold sensitivity

Patrakeeva, V. P., & Анатольевич, Ш. В. (2022) · Medicine of Extreme Situations · doi:10.47183/mes.2022.036 · Cited by 1 · see citing works

Irisin: muscle’s novel player in endoplasmic reticulum stress and disease

Pinto, J. R., Bhat, K. D., Bose, B., & Sudheer Shenoy, P. (2025) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-025-05225-y · Cited by 1 · see citing works

TRAUMA AND THE ENTEROCYTE: DISTURBANCE OF COMMUNICATION AND DELINEATION

Meisen, S., Schütte, L. D., Balmayor, E. R., Halbgebauer, R., & Huber-Lang, M. S. (2025) · Shock · doi:10.1097/shk.0000000000002564 · Cited by 1 · see citing works

Expression of irisin in the porcine pituitary gland during the oestrous cycle and early pregnancy: the role of GnRH, gonadotropins, and insulin

Zarzecka, B., Dobrzyń, K., Kieżun, M., Kopij, G., Dawid, M., Rak, A., Dall’Aglio, C., Kamiński, T., & Smolińska, N. (2025) · Reproduction Fertility and Development · doi:10.1071/rd25057 · Cited by 1 · see citing works

Protective Effects of Irisin Against LPS-Induced Intestinal Injury and Its Influence on Gut Microbiota in Septic Mice

Yang, L., Liu, M., Hu, B., Yong, K., Zhou, J., & Chen, Y. (2025) · Journal of Inflammation Research · doi:10.2147/jir.s542608 · Cited by 1 · see citing works

Molecular insights into irisin’s role in the regulation of programmed cell death: mechanisms and therapeutic potential

Yang, Y., Pullisaar, H., Reseland, J. E., & Ma, J. (2025) · Journal of Molecular Medicine · doi:10.1007/s00109-025-02623-z · Cited by 1 · see citing works

Integrin αVβ5 regulates myoblast proliferation and differentiation in sarcopenia mice treated with FNDC5 gene delivery

Gao, G., Wang, Q., Zhang, Y., Shao, M., Liang, Y., Zhou, S., & Lu, S. (2026) · Skeletal Muscle · doi:10.1186/s13395-026-00420-x · Cited by 1 · see citing works

Irisin maintains ER homeostasis and activates AMPK via integrin αVβ5 to attenuate CSE + LPS-induced emphysema and inflammation

Bai, Z., Sun, T., Chen, Z., Han, S., Li, Y., Zhang, X., Ma, C., Chen, Y., Jiang, P., Yan, X., et al. (2026) · Respiratory Research · doi:10.1186/s12931-026-03850-9 · Cited by 1 · see citing works

Research Progress of Irisin in Obesity and Related Metabolic Diseases

Zhang, Y.-N. (2023) · Advances in Clinical Medicine · doi:10.12677/acm.2023.13122830 · Cited by 1 · see citing works

Mechanisms and prevention of intestinal barrier function damage in traumatic hemorrhagic shock

Chen, F., Chu, C., & Ding, W. (2022) · World Chinese Journal of Digestology · doi:10.11569/wcjd.v30.i12.547

The role of a recently discovered peptide—irisin—in physiological and pathological processes

Bagłaj-Oleszczuk, M., & Jankowska‐Konsur, A. (2022) · Postępy Higieny i Medycyny Doświadczalnej · doi:10.2478/ahem-2022-0031

Irisin ameliorates myocardial ischemia-reperfusion injury through modulation of gut microbiota and intestinal permeability in ratsPreprint

Liu, Q., Zhu, Y., Li, G., Guo, T., Jin, M., Xi, D., Wang, S., Liu, X., Guo, S., Liu, H., et al. (2022) · Research Square · doi:10.21203/rs.3.rs-2248784/v1

Irisin deficiency exacerbates cardiac dysfunction and enhances hemorrhage injury in hemorrhage/resuscitation

Kulthinee, S., Wang, L., Slate‐Romano, J., Huang, L., Zhao, T., Dubielecka, P. M., He, J., Zhuang, S., & Zhao, T. C. (2025) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00013.2025

Additional file 6 of Inhibition of platelet activation suppresses reactive enteric glia and mitigates intestinal barrier dysfunction during sepsis

Cheng, B., Du, M., He, S., Yang, L., Wang, X., Gao, H., Chang, H., Gao, W., Li, Y., Wang, Q., et al. (2022) · Figshare · doi:10.6084/m9.figshare.21601655

Additional file 3 of Inhibition of platelet activation suppresses reactive enteric glia and mitigates intestinal barrier dysfunction during sepsis

Cheng, B., Du, M., He, S., Yang, L., Wang, X., Gao, H., Chang, H., Gao, W., Li, Y., Wang, Q., et al. (2022) · Figshare · doi:10.6084/m9.figshare.21601646

Additional file 5 of Inhibition of platelet activation suppresses reactive enteric glia and mitigates intestinal barrier dysfunction during sepsis

Cheng, B., Du, M., He, S., Yang, L., Wang, X., Gao, H., Chang, H., Gao, W., Li, Y., Wang, Q., et al. (2022) · Figshare · doi:10.6084/m9.figshare.21601652

Additional file 6 of Inhibition of platelet activation suppresses reactive enteric glia and mitigates intestinal barrier dysfunction during sepsis

Cheng, B., Du, M., He, S., Yang, L., Wang, X., Gao, H., Chang, H., Gao, W., Li, Y., Wang, Q., et al. (2022) · Figshare · doi:10.6084/m9.figshare.21427867

Additional file 1 of Inhibition of platelet activation suppresses reactive enteric glia and mitigates intestinal barrier dysfunction during sepsis

Cheng, B., Du, M., He, S., Yang, L., Wang, X., Gao, H., Chang, H., Gao, W., Li, Y., Wang, Q., et al. (2022) · Figshare · doi:10.6084/m9.figshare.21601640

Additional file 7 of Inhibition of platelet activation suppresses reactive enteric glia and mitigates intestinal barrier dysfunction during sepsis

Cheng, B., Du, M., He, S., Yang, L., Wang, X., Gao, H., Chang, H., Gao, W., Li, Y., Wang, Q., et al. (2022) · Figshare · doi:10.6084/m9.figshare.21427870

Irisin ameliorates myocardial ischemia-reperfusion injury through modulation of gut microbiota and intestinal permeability in ratsPreprint

Liu, Q., Zhu, Y., Li, G., Guo, T., Jin, M., Xi, D., Wang, S., Liu, X., Guo, S., Liu, H., et al. (2022) · Research Square · doi:10.21203/rs.3.rs-2248784/v1

Irisin ameliorates myocardial ischemia-reperfusion injury by modulating gut microbiota and intestinal permeability in rats

Liu, Q., Zhu, Y., Li, G., Guo, T., Jin, M., Xi, D., Wang, S., Liu, X., Guo, S., Liu, H., et al. (2023) · PLoS ONE · doi:10.1371/journal.pone.0291022 · Cited by 22 · see citing works

Exercise Hormone Irisin Mitigates Endothelial Barrier Dysfunction and Experimental Lung InjuryPreprint

Bi, J., Zhang, J., Ren, Y., Du, Z., Wei, S., Yang, L., Liu, C., Wang, Y., Zhang, L., Shi, Z., et al. (2019) · SSRN Electronic Journal · doi:10.2139/ssrn.3487695

Inhibition of integrin alpha v/beta 5 mitigates the protective effect induced by irisin in hemorrhage

Wang, L., Kulthinee, S., Slate‐Romano, J., Zhao, T., Shanmugam, H., Dubielecka, P. M., Zhang, L. X., Qin, G., Zhuang, S., Chin, Y. E., et al. (2023) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2023.104869 · Cited by 11 · see citing works

Irisin pretreatment ameliorates intestinal ischemia/reperfusion injury in mice through activation of the Nrf2 pathway

Du, J., Fan, X., Yang, B., Chen, Y., Liu, K., & Zhou, J. F. (2019) · International Immunopharmacology · doi:10.1016/j.intimp.2019.05.011 · Cited by 48 · see citing works