The DOI matches its Crossref record; 88 of the 88 references it cites were found in a registry or an index.
The effect of environmental humidity and temperature on skin barrier function and dermatitis
Open accessAbstract
Physicians are aware that climatic conditions negatively affect the skin. In particular, people living in equator far countries such as the Northern parts of Europe and North America are exposed to harsh weather during the winter and may experience dry and itchy skin, or deterioration of already existing dermatoses. We searched the literature for studies that evaluated the mechanisms behind this phenomenon. Commonly used meteorological terms such as absolute humidity, relative humidity and dew point are explained. Furthermore, we review the negative effect of low humidity, low temperatures and different seasons on the skin barrier and on the risk of dermatitis. We conclude that low humidity and low temperatures lead to a general decrease in skin barrier function and increased susceptible towards mechanical stress. Since pro‐inflammatory cytokines and cortisol are released by keratinocytes, and the number of dermal mast cells increases, the skin also becomes more reactive towards skin irritants and allergens. Collectively, published data show that cold and dry weather increase the prevalence and risk of flares in patients with atopic dermatitis.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The cornified envelope: a model of cell death in the skin
Candi, E., Schmidt, R., & Melino, G. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1619 · Cited by 1,776
Williams, H., Robertson, C., Stewart, A., Aït-Khaled, N., Anabwani, G., Anderson, R., Asher, I., Beasley, R., Björkstén, B., Burr, M., et al. (1999) · Journal of Allergy and Clinical Immunology · doi:10.1016/s0091-6749(99)70536-1 · Cited by 998
Stratum corneum lipids: the effect of ageing and the seasons
Rogers, J., Harding, C., Mayo, A., Banks, J., & Rawlings, A. (1996) · Archives of Dermatological Research · doi:10.1007/bf02505294 · Cited by 415
Nikolovski, J., Stamatas, G. N., Kollias, N., & Wiegand, B. C. (2008) · Journal of Investigative Dermatology · doi:10.1038/sj.jid.5701239 · Cited by 388
Tariq, S. M., Matthews, S. M., Hakim, E. A., Stevens, M., Arshad, S. H., & Hide, D. W. (1998) · Journal of Allergy and Clinical Immunology · doi:10.1016/s0091-6749(98)70164-2 · Cited by 374
Ultraviolet radiation and skin cancer: molecular mechanisms
Hussein, M. R. (2005) · Journal of Cutaneous Pathology · doi:10.1111/j.0303-6987.2005.00281.x · Cited by 352
Climate and the prevalence of symptoms of asthma, allergic rhinitis, and atopic eczema in children
Weiland, S. K., Hüsing, A., Strachan, D. P., Rzehak, P., & Pearce, N. (2004) · Occupational and Environmental Medicine · doi:10.1136/oem.2002.006809 · Cited by 341
Scott, I. R., & Harding, C. R. (1986) · Developmental Biology · doi:10.1016/0012-1606(86)90230-7 · Cited by 325
Bioengineering of the skin: Water and the stratum corneum
Edwards, D. A. (1995) · Journal of Controlled Release · doi:10.1016/0168-3659(95)90005-5 · Cited by 290
Climatic Factors Are Associated with Childhood Eczema Prevalence in the United States
Silverberg, J. I., Hanifin, J., & Simpson, E. L. (2013) · Journal of Investigative Dermatology · doi:10.1038/jid.2013.19 · Cited by 286
Cited by
Update on the Pathogenesis and Therapy of Atopic Dermatitis
Li, H., Zhang, Z., Zhang, H., Guo, Y., & Yao, Z. (2021) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-021-08880-3 · Cited by 277
Skin homeostasis: Mechanism and influencing factors
Jiao, Q., Zhi, L., You, B., Wang, G., Wu, N., & Jia, Y. (2024) · Journal of Cosmetic Dermatology · doi:10.1111/jocd.16155 · Cited by 134
Park, T. H., Park, S., Cho, M. K., & Kim, S. (2022) · Clinical and Experimental Dermatology · doi:10.1111/ced.14910 · Cited by 67
The impact of temperature on the skin barrier and atopic dermatitis
Hui-Beckman, J. W., Goleva, E., Leung, D. Y. M., & Kim, B. E. (2023) · Annals of Allergy, Asthma & Immunology · doi:10.1016/j.anai.2023.08.007 · Cited by 58
Patella, V., Florio, G., Palmieri, M., Bousquet, J., Tonacci, A., Giuliano, A., & Gangemi, S. (2020) · Pediatric Allergy and Immunology · doi:10.1111/pai.13314 · Cited by 54
Metadata
- Authors
- Engebretsen, K. A., Johansen, J. D., Kezic, S., Linneberg, A., & Thyssen, J. P.
- Venue
- Journal of the European Academy of Dermatology and Venereology
- Publisher
- Wiley
- Published
- 2015-10-08
- Volume
- 30
- Issue
- 2
- Pages
- 223-249
- ISSN
- 0926-9959 (ISSN-L)
- 1468-3083
- OpenAlex
- W1932718082
- Cited by
- 349
- References
- 88
- FWCI
- 12.62
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: The effect of environmental humidity and temperature on skin barrier function and dermatitis. https://app.cochat.ai/papers/10.1111/jdv.13301
- The paper
- Engebretsen, K. A., Johansen, J. D., Kezic, S., Linneberg, A., & Thyssen, J. P. (2016). The effect of environmental humidity and temperature on skin barrier function and dermatitis. Journal of the European Academy of Dermatology and Venereology. https://doi.org/10.1111/jdv.13301
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.