The Medial Prefrontal Cortex: Coordinator of Autonomic, Neuroendocrine and Behavioural Responses to Stress

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Deep Brain Stimulation for Treatment-Resistant Depression

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Cortical and affective regulation of autonomic coordination

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Dynorphin/Kappa-Opioid Receptor System Modulation of Cortical Circuitry

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Daily Optogenetic Stimulation of the Left Infralimbic Cortex Reverses Extinction Impairments in Male Rats Exposed to Single Prolonged Stress

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Inhibition of the left medial prefrontal cortex (mPFC) prolongs the social defeat-induced anxiogenesis in mice: Attenuation by NMDA receptor blockade in the right mPFC

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A transdiagnostic examination of anxiety and stress on executive function outcomes in disorders with social impairment.

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Maladaptive Neuroplasticity Under Stress: Insights into Neuronal and Synaptic Changes in the Prefrontal Cortex

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The omnipresence of autonomic modulation in health and disease

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Descending mechanism by which medial prefrontal cortex endocannabinoid signaling controls the development of neuropathic pain and neuronal activity of dorsal root ganglion

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Modulation of neuroplasticity-related targets following stress-induced acute escape deficit

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Cortisol trajectory, melancholia, and response to electroconvulsive therapy

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Self-experience of a negative event alters responses to others in similar states through prefrontal cortex CRF mechanisms

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Prelimbic cortex glucocorticoid receptors regulate the stress-mediated inhibition of pain contagion in male mice

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Effects of Stress on Performance during Highly Demanding Tasks in Student Pilots

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Abdominal vagal deafferentation alters affective behaviors in rats

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Coping with the multifaceted and multifunctional role of cortisol in the brain

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Atrophic Corpus Callosum Associated with Altered Functional Asymmetry in Major Depressive Disorder

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Investigations on GSK-3β/NF-kB signaling in stress and stress adaptive behavior in electric foot shock subjected mice

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Comparative Study on the Functional Connectivity of Amygdala and Hippocampal Neural Circuits in Patients With First-Episode Schizophrenia and Other High-Risk Populations

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Executive Functioning and Health

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The how and why of sleep: Motor theory and catecholamine hypothesis

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Glucocorticoid feedback paradox: a homage to Mary Dallman

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Cortical–brainstem circuitry attenuates physiological stress reactivity

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Antidepressant effects of ershiwei roudoukou pills and its active ingredient Macelignan: Multiple mechanisms involving oxidative stress, neuroinflammation and synaptic plasticity

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The Modulatory Role of Cortisol in the Regulation of Sexual Behavior in Young Males

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Maternal anxiety during pregnancy is associated with weaker prefrontal functional connectivity in adult offspring

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Loss of spines in the prelimbic cortex is detrimental to working memory in mice with early-life adversity

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Maternal separation and contact to a stranger more than reunion affect the autonomic nervous system in the mother-child dyad

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The influence of CHRNA4, COMT, and maternal sensitivity on orienting and executive attention in 6-month-old infants

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The Neurobiological Links between Stress and Traumatic Brain Injury: A Review of Research to Date

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Using SuperClomeleon to Measure Changes in Intracellular Chloride during Development and after Early Life Stress

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Sex-specific prefrontal-hypothalamic control of behavior and stress responding

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The Influence of Classroom Size and Window View on Young Children’s Executive Functions and Physiological Responses, Based on VR Technology

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Chronic restraint stress induces serotonin transporter expression in the rat adrenal glands

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Inter-individual differences in pain anticipation and pain perception in migraine: Neural correlates of migraine frequency and cortisol-to-dehydroepiandrosterone sulfate (DHEA-S) ratio

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Stress amplifies sex differences in primate prefrontal profiles of gene expression

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Exercise therapy for chronic pain: How does exercise change the limbic brain function?

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Neural networks of the mouse visceromotor cortex

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Neural Circuit Connections and Functions of Locus Coeruleus–Norepinephrine System

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GABAA receptor activation modulates the muscle sympathetic nerve activity responses at the onset of static exercise in humans

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Potentiation of GABAergic synaptic transmission by diazepam acutely increases resting beat-to-beat blood pressure variability in young adults

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Corticotropin-releasing factor receptor 1 in infralimbic cortex modulates social stress-altered decision-making

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Levodopa alters resting‐state functional connectivity more selectively in Parkinson's disease with freezing of gait

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Direct replication of task‐dependent neural activation patterns during sadness introspection in two independent adolescent samples

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Effects of Biological Sex and Stress Exposure on Ventromedial Prefrontal Regulation of Mood-Related Behaviors

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Brain correlates and functional connectivity linking stress, autonomic dysregulation, and alcohol motivation

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The negative effects of social bond disruption are partially ameliorated by sertraline administration in prairie voles

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Sleep and Parasympathetic Activity During Rest and Stress in Healthy Adolescents and Adolescents With Bipolar Disorder

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Gateway reflexes describe novel neuro-immune communications that establish immune cell gateways at specific vessels

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A top-down control of stress-induced REM sleep shortening

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Medial prefrontal cortex (A32 and A25) projections in the common marmoset: a subcortical anterograde study

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The Influence of Environmental Enrichment on Affective and Neural Consequences of Social Isolation Across Development

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Maternal Immune Activation and Enriched Environments Impact B2 SINE Expression in Stress Sensitive Brain Regions of Rodent Offspring

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Behavioral effects of chronically elevated corticosterone in subregions of the medial prefrontal cortex

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Alterations of brain network hubs in reflex syncope: Evidence from a graph theoretical analysis based on DTI

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Both Prelimbic and Infralimbic Noradrenergic Neurotransmissions Modulate Cardiovascular Responses to Restraint Stress in Rats

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Prefrontal representation of affective stimuli: importance of stress, sex, and context

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Perinatal exposure of rats to the HIV drug efavirenz affects medial prefrontal cortex cytoarchitecture

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Multimodal Neuroimaging of Obesity: From Structural-Functional Mechanisms to Precision Interventions

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Social Homeostasis: A New Paradigm for Mental Health Diagnosis and Treatment

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Evidence of central autonomic dysfunction in orthostatic hypotension of Parkinson's disease

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A Prefrontal→Periaqueductal Gray Pathway Differentially Engages Autonomic, Hormonal, and Behavioral Features of the Stress-Coping Response

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Differential roles of prelimbic and infralimbic cholinergic neurotransmissions in control of cardiovascular responses to restraint stress in rats

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Distinct neuronal excitability alterations of medial prefrontal cortex in early‐life neglect model of rats

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The meltdown pathway: A multidisciplinary account of autistic meltdowns.

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Oxidative Stress Long-term effects of Lipopolysaccharide on Hippocampus and Prefrontal cortex in Male and Female Wistar Rats

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Gating of the neuroendocrine stress responses by stressor salience in early lactating female rats is independent of infralimbic cortex activation and plasticity

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Theta burst stimulation over the prefrontal cortex: Effects on cerebral oximetry and cardiovascular measures in healthy humans

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The Neurobiology of Stress

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Chronic unpredictable stress produces hyperalgesia and promotes inhibitory drive in medial prefrontal cortex

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Cortisol, stress, and cognition in military subpopulations: A systematic review and meta-analysis

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Effects of non-invasive prefrontal neuromodulation on acute cortisol response to stress: A systematic review and meta-analysis

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5-HT2A receptor loss does not alter acute fluoxetine-induced anxiety and exhibit sex-dependent regulation of cortical immediate early gene expression

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The Clinical Role of Heart Rate Variability Assessment in Cognitively Impaired Patients and Its Applicability in Community Care Settings: A Systematic Review of the Literature

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Stress-induced brain activation: buffering role of social behavior and neuronal nicotinic receptors

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Brain adaptation to acute stress: effect of time, social buffering, and nicotinic cholinergic system

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Sex-biased transgenerational effect of maternal stress on neurodevelopment and cognitive functions

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Noncanonical EEG-BOLD coupling by default and in schizophreniaPreprint

Jacob, M., Roach, B. J., Mathalon, D. H., & Ford, J. M. (2025) · medRxiv · doi:10.1101/2025.01.14.25320216 · Cited by 4

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Two separate neural pathways, lateral and medial, for sensory decisions in mammals: switching of attention between the outer and inner cognitive worlds

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Systems and Molecular Biology of Longevity and Preventive Medicine: Brain-Energy–Microbiome–Exposome Synergies in Blue Zones and the Cilento Case

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STRESS-INDUCED C-FOS EXPRESSION IN MEDIAL PREFRONTAL CORTEX AND INFLUENCE OF TES-THERAPY

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miR-146a-3p drives major depressive disorder pathogenesis via BDNF suppression: a novel diagnostic and therapeutic target

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The neurobiology of police health, resilience, and wellness

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Association of mental health-related patient reported outcomes with blood pressure in adults and children with primary proteinuric glomerulopathies

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Effect of an endothelial regulatory module on plasma proteomics in exercising horses

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Expression of tryptophan hydroxylase in rat adrenal glands: Upregulation of TPH2 by chronic stress

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Single‐cell genomics meets systems neuroscience: Insights from mapping the brain circuitry of stress

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Time-Dependent Actions of Corticosterone on Infralimbic Cortex Pyramidal Neurons of Adult Male Rats

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Epigenetics in Health and Disease

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Neural Sources of Vagus Nerve Stimulation–Induced Slow Cortical Potentials

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Stress vulnerability and resilience in children facing COVID-19-related discrimination: A quasi-experimental study using polygenic, brain, and sociodemographic dataPreprint

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Effects of pregnancy on neuron electrophysiology in prefrontal cortex, hippocampus, and basolateral amygdala of mouse brain

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Effects of acute stress on executive functions in depression, generalised anxiety and borderline personality disorder

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Activity in a prefrontal-periaqueductal gray circuit overcomes behavioral and endocrine features of the passive coping stress response

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Regional Differentiation of the Medial Prefrontal Cortex in Regulating Adaptive Responses to Acute Emotional Stress

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Stress and the brain : role of the medial prefrontal cortex in regulation of the hypothalamic-pituitary-adrenal axis

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“Braking” the Prefrontal Cortex: The Role of Glucocorticoids and Interneurons in Stress Adaptation and Pathology

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Lateralized Effects of Medial Prefrontal Cortex Lesions on Neuroendocrine and Autonomic Stress Responses in Rats

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