Cited by 8Mobile Health and mHealth ApplicationsMedication Adherence and ComplianceMalaria Research and Control

Mobile Phone Short Message Service to Improve Malaria Pharmacoadherence in Zambia

Steury, Elinda Enright·2016·Journal of Nursing Scholarship

Abstract

Purpose: The current malaria treatment in Zambia is more than 97% effective when the regimen is strictly adhered to. However, the mean adherence rate in sub‐Saharan Africa is only 38% to 48%. Poor pharmacoadherence remains a significant barrier to malaria control and elimination. The purpose of this study was to determine if adherence rates to a six‐dose artemesinin‐based combination therapy (ACT) treatment differ between patients who received short message service (SMS) reminders and those who did not. This is the first study of its kind using SMS directly to the patient for ACT adherence in sub‐Saharan Africa. Design: An experimental, randomized controlled trial was conducted through a sample of 96 adult malaria patients at Fisenge Clinic in Zambia in 2014. Methods: The intervention group received SMS messages to remind them to take their medication according to the prescribed regimen. An electronic pillbox was used to measure pharmacoadherence for both groups, and patients were classified as probably adherent or probably nonadherent. Findings: Data were analyzed using chi‐square for association between the SMS intervention and pharmacoadherence, and logistic regression was used for predictors of adherence. No significant association was found between SMS reminders and pharmacoadherence (χ 2 = 0.19, df = 1, p = .67). Binary logistic regression indicated that there were no variables associated with adherence (p > .05). Conclusions: SMS reminder messages did not appear to improve pharmacoadherence in malaria medication. Clinical Relevance: The study indicates few implications to nursing practice due to the lack of association between SMS and adherence, but adds to current knowledge.

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Crossref · 10.1111/jnu.12216

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Research works printed but not linked: 3

  1. Chirwa C. H., 2010, Zambia: A survey by the Africa governance monitoring and advocacy project
  2. Cohen J., 2003, Methodological issues & strategies in clinical research, 427
  3. 10.1186/1475_2875_8_253 · DOI

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Authors
Steury, E. E.
Affiliations
Eastern Florida State College (US)
Corresponding author
Steury, Elinda Enright
Venue
Journal of Nursing Scholarship
Publisher
Wiley
Published
2016-05-03
Volume
48
Issue
4
Pages
354-361
ISSN
  • 0363-2792 (ISSN-L)
  • 1527-6546
  • 1547-5069
OpenAlex
W2345593849
Cited by
8
References
54
Citations by year
2024: 2 · 2022: 1 · 2020: 1 · 2019: 2 · 2018: 1 · 2017: 1
FWCI
2.49
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Nursing Scholarship (publishedVersion)
  • PubMed (publishedVersion)
Funders
University of Central Florida
Topics
  • Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
  • Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Malaria Research and Control
Keywords
malaria, short message service, SMS reminders, artemisinin-based combination therapy, medication adherence, electronic pillbox, mobile health, Zambia
MeSH terms
Assessment of Medication Adherence, Adult, Antimalarials, Drug Therapy, Combination, Female, Humans, Malaria, Male, Prospective Studies, Zambia, Program Evaluation, Drug Monitoring, Reminder Systems, Artemisinins, Medication Adherence, Text Messaging

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