The Relationship Between Knowledge, Psychological Flexibility, Anxiety and Healthy Behaviour in Stroke Patients: A Chain Mediation Model.
Open accessAbstract
Aims: To explore the mediating effects of psychological flexibility and anxiety between knowledge and health behaviour in stroke patients, and to provide a reference for improving the health behaviour of stroke patients. Design: A cross‐sectional study. Methods: A convenience sampling method was used to recruit 219 stroke patients from a tertiary hospital in China from July to November 2024. Patients were surveyed using an electronic questionnaire containing demographic questions and validated scales for stroke knowledge, psychological flexibility, anxiety and health behaviour. IBM SPSS v26.0 software and PROCESS Process macro were used for data analysis. Results: The health behaviour score of stroke patients was 54.2 ± 3.8, and health behaviour was positively correlated with stroke knowledge and negatively correlated with psychological flexibility and anxiety. There was a significant chain‐mediated effect of psychological flexibility and anxiety in the relationship between stroke knowledge and health behaviour. Conclusion: Stroke knowledge not only directly predicts health behaviour in stroke patients, but also indirectly influences the health behaviour of patients through the chain mediation of psychological flexibility and anxiety. Relevance to Clinical Practice: This study highlights the importance of caregivers focusing on the interactions between patient knowledge, psychological flexibility, anxiety and health behaviour when caring for stroke patients. Comprehensive interventions aimed at enhancing stroke patients' knowledge, improving patients' psychological flexibility and reducing anxiety have the potential to improve patient health behaviour. Patient or Public Contribution: Patients completed questionnaires. Reporting Method: The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist for cross‐sectional studies was applied to report the results.
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Claims the paper makes
11 of 38 cited sources checked · 4 supported · 0 flagged · accuracy not yet measured
- Premisecitation
Only 36.5% of stroke patients had knowledge of stroke-related warning signs and symptoms.
“It was found that only 36.5% of stroke patients had knowledge of stroke-related warning signs and symptoms, and 59.6% did not know the risk factors associated with stroke (Liang et al. 2023).”
Quote in the paperSubstantial claim1 of 1 sources checked- cites Liang et al. 2023 source
- Premisecitation
59.6% of stroke patients did not know the risk factors associated with stroke.
“It was found that only 36.5% of stroke patients had knowledge of stroke-related warning signs and symptoms, and 59.6% did not know the risk factors associated with stroke (Liang et al. 2023).”
Quote in the paperSubstantial claim1 of 1 sources checked- cites Liang et al. 2023 source
Table 3 (Results, Knowledge of stroke risk factors) classifies 59.6% of the 156 patients as having *poor* knowledge of stroke risk factors, not as knowing none of them; many identified individual risk factors. Table 2 (Results, Knowledge of stroke warning signs or symptoms) supports the sentence’s separate 36.5% figure for good knowledge of warning signs. (LLM, conf=0.86)
Experimental — accuracy not yet measured
- Premisecitation
Stroke patients have poor self-management of health behaviour.
“Stroke patients have poor self-management of health behaviour, and one study found that patients with stroke were less likely to eat one or more fruits and one or more vegetables per day, achieve weekly aerobic exercise and engage in two or three health behaviours compared to patients without stroke (Bailey et al. 2019).”
Quote in the paperSubstantial claim1 of 1 sources checked- cites Bailey et al. 2019 source
- Premisecitation
More than half of stroke patients had no urgency to change their health behaviour.
“Although patients understood what a healthy lifestyle was, they were unable to adequately assess their health-related behaviour, and more than half of them had no urgency to change their health behaviour (Brouwer-Goossensen et al. 2021).”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites Brouwer-Goossensen et al. 2021 source
- Premisecitation
There is a substantial association between post-stroke anxiety and psychological flexibility in stroke patients.
“There is a substantial association between post-stroke anxiety and psychological flexibility in stroke patients, which also affects their quality of life and mental quality (Lv et al. 2021;Stahl et al. 2024;Yuliana et al. 2023).”
Quote in the paperSubstantial claim1 of 3 sources checked- cites Lv et al. 2021
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Stahl et al. 2024 source
The Results report significant associations between lack of psychological flexibility and anxiety scores in 70 stroke survivors (HADS r = 0.47; ISR r = 0.34). That supports the quoted association. The citing sentence also says this affects quality of life and mental quality, but the passages from this paper do not establish those effects; its Discussion describes the study as correlational. (LLM, conf=0.86)
Experimental — accuracy not yet measured - cites Yuliana et al. 2023 source
- Premisecitation
Psychological interventions to reduce patients' anxiety effectively improve patients' health behaviour.
“through psychological interventions to reduce the psychological distress of patients' anxiety, patients' health behaviour has been effectively improved (Xu et al. 2023;Gawande et al. 2019)”
Quote in the paperSubstantial claim1 of 2 sources checked- cites Xu et al. 2023
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Gawande et al. 2019 source
The Action Plan Initiation results report more health-behavior plan initiation after mindfulness training than after the low-dose comparator. But the Health and Self-regulation Outcomes Analysis reports no significant between-group difference in anxiety, and the paper does not establish that reducing anxiety caused the behavior change. The claim overstates that proposed pathway. (LLM, conf=0.88)
Experimental — accuracy not yet measured
- Findingown data
Stroke knowledge was positively correlated with health behaviour in stroke patients (r = 0.521, p < 0.001).
“knowledge was negatively correlated with psychological flexibility (r = -0.326,p < 0.001) and anxiety (r = -0.515,p < 0.001), and positively correlated with stroke health behaviour (r = 0.521, p < 0.001).”
Quote in the paperSubstantial claim - Findingreasoning
Patients' knowledge about stroke was at a low level in this study.
“In the present study, patients' knowledge about stroke was at a low level, probably because the population investigated in this study was predominantly rural and elderly,”
Quote in the paperNot a substantial claim - Findingown data
Stroke knowledge was negatively correlated with anxiety in stroke patients (r = -0.515, p < 0.001).
“knowledge was negatively correlated with psychological flexibility (r = -0.326,p < 0.001) and anxiety (r = -0.515,p < 0.001), and positively correlated with stroke health behaviour (r = 0.521, p < 0.001).”
Quote in the paperSubstantial claim - Findingown data
Psychological flexibility positively predicted anxiety (β = 0.275, p < 0.001).
“In Equation 2, psychological flexibility positively predicted anxiety (β = 0.275, p < 0.001).”
Quote in the paperSubstantial claim - Findingown data
Psychological flexibility was positively correlated with anxiety in stroke patients (r = 0.426, p < 0.001).
“Psychological flexibility was positively correlated with anxiety (r = 0.426, p < 0.001) and negatively correlated with stroke health behaviour (r = -0.386,p < 0.001).”
Quote in the paperSubstantial claim - Findingown data
The health behaviour score of stroke patients was 54.2 ± 3.8.
“The health behaviour score of stroke patients was 54.2 ± 3.8, and health behaviour was positively correlated with stroke knowledge and negatively correlated with psychological flexibility and anxiety.”
Quote in the paperNot a substantial claim - Findingown data
Psychological flexibility was negatively correlated with health behaviour in stroke patients (r = -0.386, p < 0.001).
“Psychological flexibility was positively correlated with anxiety (r = 0.426, p < 0.001) and negatively correlated with stroke health behaviour (r = -0.386,p < 0.001).”
Quote in the paperSubstantial claim - Findingown data
Anxiety was negatively correlated with health behaviour in stroke patients (r = -0.447, p < 0.001).
“Anxiety was negatively correlated with stroke health behaviour (r = -0.447,p < 0.001).”
Quote in the paperSubstantial claim - Findingown data
Stroke knowledge was significantly associated with psychological flexibility (β = -0.321, p < 0.001).
“Stroke knowledge was significantly associated with psychological flexibility (β = -0.321,p < 0.001), anxiety (β = -0.511,p < 0.001), and health behaviour (β = 0.487, p < 0.001).”
Quote in the paperSubstantial claim - Findingown data
The three indirect effects accounted for 14.37%, 21.77% and 3.70% of the overall effect, respectively.
“The proportion of the above three indirect effects accounted for 14.37%, 21.77% and 3.70%, respectively.”
Quote in the paperNot a substantial claim - Findingown data
Psychological flexibility negatively predicted health behaviour (β = -0.218, p = 0.001).
“In Equation 4, psychological flexibility and anxiety negatively predicted health behaviour, respectively (β = -0.218,p = 0.001; β = -0.208,p = 0.005).”
Quote in the paperSubstantial claim - Findingown data
Stroke knowledge was significantly associated with health behaviour (β = 0.487, p < 0.001).
“Stroke knowledge was significantly associated with psychological flexibility (β = -0.321,p < 0.001), anxiety (β = -0.511,p < 0.001), and health behaviour (β = 0.487, p < 0.001).”
Quote in the paperSubstantial claim - Findingown data
The overall effect of stroke knowledge on health behaviour was 0.487 (95% CI: 0.279, 0.465).
“The overall effect of stroke knowledge on health behaviour was 0.487 (95% CI: 0.279, 0.465), and the direct and indirect effects of stroke knowledge on health behaviours were 0.293 and 0.194, which accounted for the overall effects of 60.16% and 39.84%, respectively.”
Quote in the paperSubstantial claim - Findingown data
Anxiety negatively predicted health behaviour (β = -0.208, p = 0.005).
“In Equation 4, psychological flexibility and anxiety negatively predicted health behaviour, respectively (β = -0.218,p = 0.001; β = -0.208,p = 0.005).”
Quote in the paperSubstantial claim - Findingown data
Age, education, monthly income, living condition and history of stroke were influencing factors of health behaviour in stroke patients.
“This study showed that the score of health behaviour of stroke patients was low, and it was also found that age, education, monthly income, living condition and history of stroke were the influencing factors of the health behaviour of stroke patients, which was consistent with the research of Sun et al. (Sun et al. 2024)”
Quote in the paperSubstantial claim - Findingown data
Stroke knowledge was significantly associated with anxiety (β = -0.511, p < 0.001).
“Stroke knowledge was significantly associated with psychological flexibility (β = -0.321,p < 0.001), anxiety (β = -0.511,p < 0.001), and health behaviour (β = 0.487, p < 0.001).”
Quote in the paperSubstantial claim - Findingown data
Stroke knowledge was negatively correlated with psychological flexibility in stroke patients (r = -0.326, p < 0.001).
“knowledge was negatively correlated with psychological flexibility (r = -0.326,p < 0.001) and anxiety (r = -0.515,p < 0.001), and positively correlated with stroke health behaviour (r = 0.521, p < 0.001).”
Quote in the paperSubstantial claim - Findingown data
When both psychological flexibility and anxiety were included in the regression analysis, stroke knowledge was positively correlated with health behaviour (β = 0.293, p < 0.001).
“In Equation 3, when both psychological flexibility and anxiety were included in the regression analysis, stroke knowledge was positively correlated with health behaviour (β = 0.293, p < 0.001), indicating that psychological flexibility and anxiety partially mediated the relationship between stroke knowledge and health behaviour.”
Quote in the paperSubstantial claim - Findingown data
Most stroke patients in this study had low psychological flexibility.
“This study found that most patients had low psychological flexibility, which is consistent with the study by Tian et al. (Tian et al. 2024) and highlights the common problem of low psychological flexibility in stroke patients.”
Quote in the paperNot a substantial claim - Findingcitation
Psychological flexibility positively predicted health behaviour in stroke patients.
“We also found that psychological flexibility was negatively influenced by stroke knowledge and positively predicted health behaviour in stroke patients.”
Quote in the paperSubstantial claim - Findingown data
The health behaviour of stroke patients is at a medium-low level.
“This study proves that the health behaviour of stroke patients is at a medium-low level, which is significantly related to stroke knowledge, psychological flexibility and anxiety.”
Quote in the paperSubstantial claim - Findingown data
Health behaviour of stroke patients is significantly related to psychological flexibility.
“This study proves that the health behaviour of stroke patients is at a medium-low level, which is significantly related to stroke knowledge, psychological flexibility and anxiety.”
Quote in the paperSubstantial claim - Findingown data
Stroke knowledge negatively influenced psychological flexibility in stroke patients.
“We also found that psychological flexibility was negatively influenced by stroke knowledge and positively predicted health behaviour in stroke patients.”
Quote in the paperSubstantial claim - Findingown data
Health behaviour of stroke patients is significantly related to stroke knowledge.
“This study proves that the health behaviour of stroke patients is at a medium-low level, which is significantly related to stroke knowledge, psychological flexibility and anxiety.”
Quote in the paperSubstantial claim - Findingown data
Health behaviour of stroke patients is significantly related to anxiety.
“This study proves that the health behaviour of stroke patients is at a medium-low level, which is significantly related to stroke knowledge, psychological flexibility and anxiety.”
Quote in the paperSubstantial claim - Findingreasoning
Psychological flexibility mediates the relationship between stroke knowledge and health behaviour in stroke patients.
“In addition, we confirmed the mediating role of psychological flexibility between knowledge and health behaviour in stroke patients.”
Quote in the paperSubstantial claim - Findingown data
Psychological flexibility and anxiety serially mediate the relationship between stroke knowledge and health behaviour, accounting for 3.7% of the total effect.
“The present study further confirmed that psychological flexibility and anxiety played a continuous mediating role between stroke knowledge and health behaviour, accounting for 3.7% of the total effect.”
Quote in the paperSubstantial claim - Findingown data
The overall level of anxiety in stroke patients in this study was mild.
“In this study, it was found that the overall level of anxiety in stroke patients was mild and that younger, female patients were more likely to be anxious (Zhang et al. 2023;Solgajová et al. 2017), which requires urgent attention from healthcare professionals.”
Quote in the paperNot a substantial claim - Findingreasoning
Lower stroke knowledge is associated with higher anxiety in stroke patients.
“Stroke knowledge was also found to influence the level of patient anxiety, with patients with lower stroke knowledge more likely to be anxious, probably due to the lack of knowledge of the disease, uncertainty about the effectiveness of treatment and prognosis of the disease, and fear of the disease progression, which led to anxiety.”
Quote in the paperSubstantial claim - Findingreasoning
Patients with greater stroke knowledge have greater psychological flexibility.
“Stroke knowledge can provide favourable conditions for the development of psychological flexibility, and patients with greater stroke knowledge have greater psychological flexibility.”
Quote in the paperSubstantial claim - Interpretationown data
Psychological flexibility and anxiety partially mediated the relationship between stroke knowledge and health behaviour.
“In Equation 3, when both psychological flexibility and anxiety were included in the regression analysis, stroke knowledge was positively correlated with health behaviour (β = 0.293, p < 0.001), indicating that psychological flexibility and anxiety partially mediated the relationship between stroke knowledge and health behaviour.”
Quote in the paperSubstantial claim - Premisecitation
The level of psychological flexibility of recovering stroke patients was low.
“Tian Lingling found that the level of psychological flexibility of patients was low through a survey of 156 recovering stroke patients (Tian et al. 2024).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Tian et al. 2024
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Premisecitation
Lack of stroke knowledge may lead to delays in seeking medical treatment.
“The lack of stroke knowledge may not only lead to delays in seeking medical treatment (Dong et al. 2024), which affects the prognosis of the patients, but also lead to the maintenance of poor health behaviour in the patients, which can increase the chance of recurrence in stroke patients.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Dong et al. 2024 source
- Interpretationown data
The health behaviour score of stroke patients was low.
“This study showed that the score of health behaviour of stroke patients was low, and it was also found that age, education, monthly income, living condition and history of stroke were the influencing factors of the health behaviour of stroke patients, which was consistent with the research of Sun et al. (Sun et al. 2024)”
Quote in the paperSubstantial claim - Premisecitation
There is a significant predictive causal correlation between higher knowledge and higher health behaviour in stroke patients.
“Similarly, Mun and Shim (Mun and Shim 2024), Parappilly et al. (Parappilly et al. 2019) emphasised that there is a significant predictive causal correlation between higher knowledge and higher health behaviour in stroke patients.”
Quote in the paperSubstantial claim0 of 2 sources checked - Interpretationreasoning
The single-center design and recruitment from one city in China may limit generalisability to all stroke patients in China.
“Firstly, this is a single-center study and we recruited participants from only one city in China, which may limit the generalisability of the results to all stroke patients in China.”
Quote in the paperNot a substantial claim - Interpretationreasoning
Stroke knowledge can provide favourable conditions for the development of psychological flexibility.
“Stroke knowledge can provide favourable conditions for the development of psychological flexibility, and patients with greater stroke knowledge have greater psychological flexibility.”
Quote in the paperSubstantial claim - Premisecitation
Anxiety affected patients' health behaviour.
“some scholars have shown that anxiety affected patients' health behaviour, and there was a relationship between it and cardiovascular health (He et al. 2022)”
Quote in the paperSubstantial claim0 of 1 sources checked- cites He et al. 2022
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Interpretationreasoning
The higher the level of stroke knowledge, the better patients can cope with the disease.
“This may be because the higher the level of stroke knowledge of the patients and the more familiar they are with stroke prevention and management, the better and more positively the patients can cope with the disease.”
Quote in the paperSubstantial claim
- May combine two claims. 21
- The quote only partly states this claim. 1
- Classified as probably not a substantial claim. 20
May combine two claims.
PremisecitationPost-stroke anxiety and psychological flexibility affect quality of life and mental quality in stroke patients.
“There is a substantial association between post-stroke anxiety and psychological flexibility in stroke patients, which also affects their quality of life and mental quality (Lv et al. 2021;Stahl et al. 2024;Yuliana et al. 2023).”
Quote in the paperSubstantial claim1 of 3 sources checked- cites Lv et al. 2021
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Stahl et al. 2024 source
The Results (Table 2; page unavailable) report a significant association between lack of psychological flexibility and anxiety-disorder symptoms in stroke survivors. The Methods > Outcomes section lists measures of psychopathology and flexibility, but not quality of life or “mental quality”; the Discussion > Limitations also cautions that the correlational design cannot establish causality. Thus the source supports the association, not the claimed effects on quality of life or mental quality. (LLM, conf=0.88)
Experimental — accuracy not yet measured - cites Yuliana et al. 2023 source
May combine two claims.
PremisecitationPatients with stroke were less likely to eat one or more fruits and one or more vegetables per day, achieve weekly aerobic exercise and engage in two or three health behaviours compared to patients without stroke.
“Stroke patients have poor self-management of health behaviour, and one study found that patients with stroke were less likely to eat one or more fruits and one or more vegetables per day, achieve weekly aerobic exercise and engage in two or three health behaviours compared to patients without stroke (Bailey et al. 2019).”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites Bailey et al. 2019 source
May combine two claims.
PremisecitationPatients with high psychological flexibility can effectively regulate their emotional responses while coping with the disease and experience fewer negative emotions, which leads to more positive self-health management.
“In addition, patients with high psychological flexibility can effectively regulate their emotional responses while coping with the disease and experience fewer negative emotions (Morimoto 2024;Deng et al. 2023), which leads to more positive self-health management.”
Quote in the paperSubstantial claim2 of 2 sources checked- cites Morimoto 2024 source
The Introduction defines psychological flexibility partly in terms of allowing painful emotions, and Results §3.3 finds lower depression and anxiety in dementia family caregivers with high psychological flexibility. The cited finding concerns caregivers, not patients coping with their own disease; it does not establish that they effectively regulate emotional responses. The subsequent claim about self-health management is outside the citation’s immediate scope and is not addressed by this study. (LLM, conf=0.86)
Experimental — accuracy not yet measured - cites Deng et al. 2023 source
The Results (Correlations Between Profile and Mental Health Outcomes; page unavailable) report lower negative affect in the active psychological-flexibility group, and the Discussion describes its acceptance and harnessing of distress. The study concerns Chinese college students during COVID-19, not patients coping with a disease, and it does not establish that flexibility enables emotional regulation. The self-health-management clause follows the citation and appears to be the citing authors’ inference; this paper does not test it. (LLM, conf=0.86)
Experimental — accuracy not yet measured
May combine two claims.
FindingcitationYounger and female stroke patients were more likely to be anxious.
“In this study, it was found that the overall level of anxiety in stroke patients was mild and that younger, female patients were more likely to be anxious (Zhang et al. 2023;Solgajová et al. 2017), which requires urgent attention from healthcare professionals.”
Quote in the paperNot a substantial claim1 of 2 sources checked- cites Zhang et al. 2023 source
The Discussion identifies female sex as a risk factor for post-stroke anxiety in the study’s rural ischaemic stroke survivors. It does not support the younger-age part: the Results subgroup analysis reports no significant difference in anxiety profiles by age (p = 0.541). (LLM, conf=0.90)
Experimental — accuracy not yet measured - cites Solgajová et al. 2017
May combine two claims.
Findingown dataThe indirect effect of stroke knowledge on health behaviour was 0.194, accounting for 39.84% of the overall effect.
“The overall effect of stroke knowledge on health behaviour was 0.487 (95% CI: 0.279, 0.465), and the direct and indirect effects of stroke knowledge on health behaviours were 0.293 and 0.194, which accounted for the overall effects of 60.16% and 39.84%, respectively.”
Quote in the paperSubstantial claimThe quote only partly states this claim.
Findingown dataPsychological flexibility and anxiety mediated the effect of stroke knowledge on health behaviour, with an effect value of 0.018 (95% CI: 0.004, 0.037).
“There was a significant chain-mediated effect of psychological flexibility and anxiety in the relationship between stroke knowledge and health behaviour.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataThe direct effect of stroke knowledge on health behaviour was 0.293, accounting for 60.16% of the overall effect.
“The overall effect of stroke knowledge on health behaviour was 0.487 (95% CI: 0.279, 0.465), and the direct and indirect effects of stroke knowledge on health behaviours were 0.293 and 0.194, which accounted for the overall effects of 60.16% and 39.84%, respectively.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataAnxiety is negatively correlated with health behaviour in stroke patients; anxious patients had poorer health behaviour.
“This study also found a negative correlation between anxiety and health behaviour, i.e., anxious patients had poorer health behaviour.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataA total of 219 valid questionnaires were collected.
“A total of 219 valid questionnaires were collected.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataIn this study, the Cronbach's alpha for the Health Behaviour Scale for Stroke Patients was 0.71.
“In this study, the Cronbach's alpha was 0.71.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim. May combine two claims.
PremisecitationPatients with higher psychological flexibility had higher levels of healthy lifestyle promotion and better quality of life.
“Previous studies had shown that patients with higher psychological flexibility had higher levels of healthy lifestyle promotion and better quality of life (Li et al. 2024;Lv et al. 2021).”
Quote in the paperSubstantial claim0 of 2 sources checked- cites Li et al. 2024
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Lv et al. 2021
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Probably not a substantial claim: may not pass S3 (load-bearing).
Premisecitation35% of patients have post-stroke anxiety.
“Anxiety is a common complication in post-stroke patients, and some studies have shown that 35% of patients have poststroke anxiety (Ruthmann et al. 2025).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Ruthmann et al. 2025 source
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataIn this study, the Cronbach's alpha for the Stroke Knowledge Questionnaire was 0.79.
“In this study, the Cronbach's alpha was 0.79.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataIn this study, the Cronbach's alpha for the General Anxiety Scale was 0.81.
“In this study Cronbach's alpha was 0.81.”
Quote in the paperNot a substantial claimMay combine two claims.
Interpretationown dataStroke knowledge directly affects health behaviour and indirectly affects health behaviour through the chain mediation of psychological flexibility and anxiety.
“Stroke knowledge not only directly predicts health behaviour in stroke patients, but also indirectly influences the health behaviour of patients through the chain mediation of psychological flexibility and anxiety.”
- Also stated in: § 5 | Discussion · plain
“Consistent with our previous hypothesis, stroke knowledge not only directly affects health behaviour, but also indirectly through psychological flexibility and anxiety.”
Quote in the paperSubstantial claim- Also stated in: § 5 | Discussion · plain
Classified as probably not a substantial claim. May combine two claims.
PremisecitationDisease perception, anxiety and depression negatively influenced self-management in stroke patients.
“Some studies had found that patient self-efficacy and social support positively influenced self-management in stroke patients, and disease perception, anxiety and depression negatively influenced selfmanagement in stroke patients (Zhang et al. 2024)”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Zhang et al. 2024
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Classified as probably not a substantial claim.
InterpretationcitationDifferent patients will have different beliefs, opinions and thus different behaviour after being subjected to the stimulating event of stroke.
“That is, different patients will have different beliefs, opinions and thus different behaviour after being subjected to the stimulating event of stroke.”
Quote in the paperSubstantial claimMay combine two claims.
Study design and conductcitationThe Stroke Knowledge Questionnaire had a content validity of 0.95 and Cronbach's alpha of 0.86.
“The questionnaire had a content validity of 0.95 and Cronbach's alpha of 0.86 (Yao 2016).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Yao 2016
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
May combine two claims.
Study design and conductcitationThe final valid questionnaires of this study were 219 cases, which satisfied the minimum requirement of the sample size of 200 people for structural equation modelling.
“The final valid questionnaires of this study were 219 cases, which satisfied the minimum requirement of the sample size of 200 people for structural equation modelling (McDonald and Ho 2002).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites McDonald and Ho 2002 source
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationGood health behaviour only accounted for 19.9% of stroke patients.
“Chinese scholars classified the health behaviour of stroke patients into unstable health behaviour, good health behaviour and low health behaviour, of which good health behaviour only accounted for 19.9% (Guo et al. 2023).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Guo et al. 2023
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationPatient self-efficacy and social support positively influenced self-management in stroke patients.
“Some studies had found that patient self-efficacy and social support positively influenced self-management in stroke patients, and disease perception, anxiety and depression negatively influenced selfmanagement in stroke patients (Zhang et al. 2024)”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Zhang et al. 2024
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Classified as probably not a substantial claim.
PremisecitationEllis's ABC theoretical model indicates that when confronted with the same activating event, different individuals hold different beliefs about the event, which can lead to different consequences.
“Ellis's ABC theoretical model (Ellis 1991) indicates that when confronted with the same activating event (Activating Event, A), different individuals hold different beliefs (Belief, B) about the event, which can lead to different consequences (Consequence, C).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Ellis 1991 source
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataIn this study, the Cronbach's alpha for the Comprehensive Assessment of Acceptance and Commitment Therapy Processes was 0.73.
“In this study, the Cronbach's alpha was 0.73.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductcitationThe Health Behaviour Scale for Stroke Patients had a Cronbach's alpha of 0.88 and a content validity of 0.85.
“The original scale had a Cronbach's alpha of 0.88 and a content validity of 0.85 (Wan et al. 2017).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Wan et al. 2017
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductcitationThe Chinese version of the General Anxiety Scale had a Cronbach's alpha of 0.90.
“The Chinese version of Cronbach's alpha was 0.90 (He et al. 2010), and in this study Cronbach's alpha was 0.81.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites He et al. 2010
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductnone givenThe cross-sectional design can only show correlation between variables and does not indicate causality.
“In addition, this was a crosssectional study, which can only show the correlation between the variables and does not indicate causality.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductnone givenThis study was approved by the ethics committee of the first author's institution (No. 2022-KY-1168-001).
“This study was approved by the ethics committee of the first author's institution (No. 2022-KY-1168-001).”
Quote in the paperNot a substantial claimMay combine two claims.
InterpretationreasoningStroke knowledge can reduce patients' anxiety by improving their psychological flexibility, which ultimately improves their health behaviour.
“That is, stroke knowledge can reduce patients' anxiety by improving their psychological flexibility, which ultimately improves their health behaviour.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductcitationThis study was reported following the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist for cross-sectional studies.
“This study was reported following the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist for cross-sectional studies.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites STROBE
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductnone givenAll participants gave informed consent before data collection and could withdraw at any time.
“All participants gave informed consent before data collection and could withdraw at any time.”
Quote in the paperNot a substantial claimMay combine two claims.
Interpretationown dataLack of knowledge of stroke might lead to a decrease in patients' psychological flexibility and anxiety, and ultimately had a negative impact on patients' health behaviour.
“This study showed that the lack of knowledge of stroke might lead to a decrease in patients' psychological flexibility and anxiety, and ultimately had a negative impact on patients' health behaviour.”
Quote in the paperSubstantial claimMay combine two claims.
PremisecitationThe more psychological flexibility patients have, the better their health behaviour and the more positive changes in response to poor lifestyle habits.
“The more psychological flexibility the patients have will lead to better health behaviour (Hooker et al. 2020) and more positive changes in response to poor lifestyle habits.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Hooker et al. 2020 source
May combine two claims.
InterpretationreasoningThe health behaviour of patients can be improved by increasing patients' psychological flexibility and reducing their anxiety.
“These results suggest that the health behaviour of patients can be improved by increasing patients' psychological flexibility and reducing their anxiety.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationThere is a relationship between anxiety and cardiovascular health.
“some scholars have shown that anxiety affected patients' health behaviour, and there was a relationship between it and cardiovascular health (He et al. 2022)”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites He et al. 2022
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductcitationThe Comprehensive Assessment of Acceptance and Commitment Therapy Processes had a Cronbach's alpha of 0.87.
“The Cronbach's alpha of the scale was 0.87 (Wang et al. 2018).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Wang et al. 2018
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
May combine two claims.
PremisecitationPatients with a high level of stroke disease knowledge were better able to understand and solve health-related issues and disease coping skills, which led to the use of correct information to manage the disease and improve their health behaviour.
“In addition, it has been stated that patients with a high level of stroke disease knowledge were better able to understand and solve health-related issues and disease coping skills (Liu et al. 2024), which led to the use of correct information to manage the disease and improve their health behaviour.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Liu et al. 2024 source
The paper relies on this without support.
It is unclear how knowledge, psychological flexibility, anxiety and health behaviour simultaneously influence health behaviour in stroke patients.
“However, it is unclear how these factors simultaneously influence health behaviour.”
The paper relies on this without support.
Less is known about psychological flexibility and anxiety as chain mediators between knowledge and health behaviour.
“In addition, less is known about psychological flexibility and anxiety as chain mediators between knowledge and health behaviour.”
The paper relies on this without support.
This is the first study to provide evidence for a chain-mediated role of psychological flexibility and anxiety between knowledge and health behaviour in stroke patients.
“This is the first study to provide evidence for a chain-mediated role of psychological flexibility and anxiety between knowledge and health behaviour in stroke patients.”
The paper relies on this without support.
Lack of stroke knowledge leads to maintenance of poor health behaviour and increased chance of recurrence in stroke patients.
“The lack of stroke knowledge may not only lead to delays in seeking medical treatment (Dong et al. 2024), which affects the prognosis of the patients, but also lead to the maintenance of poor health behaviour in the patients, which can increase the chance of recurrence in stroke patients.”
The paper relies on this without support.
There is an urgent need to improve patients' stroke knowledge to enhance their health behaviour.
“Therefore, there is an urgent need to improve patients' stroke knowledge to enhance their health behaviour.”
The paper relies on this without support.
A better understanding of the psychological factors that influence the relationship between knowledge and health behaviour among stroke patients will be beneficial.
“In addition, a better understanding of the psychological factors that influence the relationship between knowledge and health behaviour among stroke patients will be beneficial.”
The paper relies on this without support.
The mechanism of the relationship between anxiety and adverse clinical outcomes is not clear.
“At present, the mechanism of the relationship between anxiety and adverse clinical outcomes is not clear”
The paper relies on this without support.
Stroke patients have fewer ways of acquiring knowledge about the disease.
“and this population had fewer ways of acquiring knowledge about the disease.”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
Flexibility-behaviour relationship changes direction
MajorThe abstract describes a negative correlation between health behaviour and psychological flexibility, whereas the discussion says greater flexibility leads to better health behaviour. A negative correlation with the reverse-scored Comp ACT measure would support the latter claim, not the abstract's wording.
“health behaviour was positively correlated with stroke knowledge and negatively correlated with psychological flexibility and anxiety.”
“The more psychological flexibility the patients have will lead to better health behaviour”
Total-effect estimate falls outside its confidence interval
MinorThe reported total effect is 0.487, but its stated 95% confidence interval ends at 0.465. The point estimate cannot lie above the upper bound of its own confidence interval.
“The overall effect of stroke knowledge on health behaviour was 0.487”
“(95% CI: 0.279, 0.465)”
Low knowledge is said both to lower anxiety and to increase it
MinorThe clinical implications say that lacking stroke knowledge may decrease anxiety. The discussion instead says patients with less knowledge are more likely to be anxious.
“the lack of knowledge of stroke might lead to a decrease in patients' psychological flexibility and anxiety”
“patients with lower stroke knowledge more likely to be anxious”
Knowledge-flexibility relationship is described in opposite directions
MinorThe results call the association between stroke knowledge and psychological flexibility negative, while the discussion says greater knowledge accompanies greater flexibility. The scale is reverse-scored, which may explain the mix-up, but the statements about flexibility itself conflict.
“knowledge was negatively correlated with psychological flexibility (r = -0.326,p < 0.001)”
“patients with greater stroke knowledge have greater psychological flexibility.”
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Cited by
Sorted by citations
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- Authors
- Ma, R., Qiao, M., Zhou, Y., Sun, W., Lv, Y., Zhou, X., Wang, Y., Wu, X., & Yu, R.
- Affiliations
- Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan China
- First Affiliated Hospital of Zhengzhou University (CN)
- Venue
- Journal of Clinical Nursing
- Publisher
- Wiley
- Published
- 2025-05-06
- Volume
- 35
- Issue
- 1
- Pages
- 219-228
- ISSN
- 0962-1067 (ISSN-L)
- 1365-2702
- OpenAlex
- W4410178379
- Semantic Scholar
- e52deb24c151901749a465cee3c81324f4dbfaea
- Cited by
- 3
- References
- 31
- Citations by year
- 2026: 2 · 2025: 1
- FWCI
- 3.76
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Clinical Nursing (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Health Professions › General Health Professions › Health and Wellbeing Research
- Health Sciences › Medicine › Rehabilitation › Stroke Rehabilitation and Recovery
- Health Sciences › Health Professions › Pharmacy › Nursing care and research
- Keywords
- stroke, stroke knowledge, psychological flexibility, anxiety, health behavior, serial mediation, stroke patients, patient education, caregiver interventions
- MeSH terms
- Adult, Aged, Anxiety, China, Cross-Sectional Studies, Female, Humans, Health Knowledge, Attitudes, Practice, Male, Middle Aged, Surveys and Questionnaires, Health Behavior, Stroke
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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Classified by jev-1.13-20260917 (gold-guideline-v0.2) on 2026-10-11.
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