The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.
COVID‐19 diagnosis and management: a comprehensive review
Open accessAbstract
Severe acute respiratory syndrome coronavirus (SARS‐CoV)‐2, a novel coronavirus from the same family as SARS‐CoV and Middle East respiratory syndrome coronavirus, has spread worldwide leading the World Health Organization to declare a pandemic. The disease caused by SARS‐CoV‐2, coronavirus disease 2019 (COVID‐19), presents flu‐like symptoms which can become serious in high‐risk individuals. Here, we provide an overview of the known clinical features and treatment options for COVID‐19. We carried out a systematic literature search using the main online databases (PubMed, Google Scholar, MEDLINE, UpToDate, Embase and Web of Science) with the following keywords: ‘COVID‐19’, ‘2019‐nCoV’, ‘coronavirus’ and ‘SARS‐CoV‐2’. We included publications from 1 January 2019 to 3 April 2020 which focused on clinical features and treatments. We found that infection is transmitted from human to human and through contact with contaminated environmental surfaces. Hand hygiene is fundamental to prevent contamination. Wearing personal protective equipment is recommended in specific environments. The main symptoms of COVID‐19 are fever, cough, fatigue, slight dyspnoea, sore throat, headache, conjunctivitis and gastrointestinal issues. Real‐time PCR is used as a diagnostic tool using nasal swab, tracheal aspirate or bronchoalveolar lavage samples. Computed tomography findings are important for both diagnosis and follow‐up. To date, there is no evidence of any effective treatment for COVID‐19. The main therapies being used to treat the disease are antiviral drugs, chloroquine/hydroxychloroquine and respiratory therapy. In conclusion, although many therapies have been proposed, quarantine is the only intervention that appears to be effective in decreasing the contagion rate. Specifically designed randomized clinical trials are needed to determine the most appropriate evidence‐based treatment modality.
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Cites
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Huang, C., Wang, Y., Li, X., Ren, L., Zhao, J., Hu, Y., Zhang, L., Fan, G., Xu, J., Gu, X., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30183-5 · Cited by 48,884
Clinical characteristics of coronavirus disease 2019 in China
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The Psychological Impact of Quarantine and How to Reduce It: Rapid Review of the Evidence
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The psychological impact of quarantine and how to reduce it: Rapid review of the evidence
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Pathological findings of COVID-19 associated with acute respiratory distress syndrome
Xu, Z., Shi, L., Wang, Y., Zhang, J., Huang, L., Zhang, C., Liu, S., Zhao, P., Liu, H., Zhu, L., et al. (2020) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(20)30076-x · Cited by 8,545
First case of 2019 novel coronavirus in the United States
Holshue, M. L., DeBolt, C., Lindquist, S., Lofy, K. H., Wiesman, J., Bruce, H., Spitters, C., Ericson, K., Wilkerson, S., Tural, A., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2001191 · Cited by 6,030
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Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus
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Cited by
Clinical manifestations of COVID-19 in the general population: systematic review
da Rosa Mesquita, R., Francelino Silva Junior, L. C., Santos Santana, F. M., Farias de Oliveira, T., Campos Alcântara, R., Monteiro Arnozo, G., Rodrigues da Silva Filho, E., Galdino dos Santos, A. G., Oliveira da Cunha, E. J., Salgueiro de Aquino, S. H., et al. (2021) · Wiener klinische Wochenschrift · doi:10.1007/s00508-020-01760-4 · Cited by 394
Miller, T. E., Garcia Beltran, W. F., Bard, A. Z., Gogakos, T., Anahtar, M. N., Astudillo, M. G., Yang, D., Thierauf, J., Fisch, A. S., Mahowald, G. K., et al. (2020) · The FASEB Journal · doi:10.1096/fj.202001700rr · Cited by 148
The coronavirus disease 2019 vaccine in pregnancy: risks, benefits, and recommendations
Stafford, I. A., Parchem, J. G., & Sibai, B. M. (2021) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2021.01.022 · Cited by 89
Code status documentation at admission in COVID-19 patients: a descriptive cohort study
Briedé, S., van Goor, H. M. R., de Hond, T. A. P., van Roeden, S. E., Staats, J. M., Oosterheert, J. J., van den Bos, F., & Kaasjager, K. A. H. (2021) · BMJ Open · doi:10.1136/bmjopen-2021-050268 · Cited by 10
Metadata
- Authors
- Pascarella, G., Strumia, A., Piliego, C., Bruno, F., Del Buono, R., Costa, F., Scarlata, S., & Agrò, F. E.
- Venue
- Journal of Internal Medicine
- Publisher
- Wiley
- Published
- 2020-05-13
- Volume
- 288
- Issue
- 2
- Pages
- 192-206
- ISSN
- 0954-6820 (ISSN-L)
- 1365-2796
- OpenAlex
- W3019086896
- Cited by
- 1,369
- References
- 21
- FWCI
- 36.24
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Pascarella, G., Strumia, A., Piliego, C., Bruno, F., Del Buono, R., Costa, F., Scarlata, S., & Agrò, F. E. (2020). COVID‐19 diagnosis and management: a comprehensive review. Journal of Internal Medicine. https://doi.org/10.1111/joim.13091
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
