CoChat
Sign Up
Cited by 79Vitamin D Research StudiesVitamin K Research StudiesNutrition and Health Studies

Vitamin D deficiency in pregnancy – still a public health issue

Open access
McAree, Trixie, Jacobs, Benjamin, Manickavasagar, Thubeena, Velagala, Suganthinie, Brennan, Lauren, Bassett, Paul, Rainbow, Sandra, Blair, Mitch·2013·Maternal & Child Nutrition
DOI 10.1111/mcn.12014PMC PMC6860546
Open this paper in CoChat — free account

Abstract

The objectives of this study were to quantify the prevalence of vitamin D insufficiency and deficiency in pregnancy, explore associated risk factors and discuss the public health implications. The study used retrospective analysis of randomly selected data. This is the first report on serum vitamin D levels in an unselected multi‐ethnic population of pregnant women collected between A pril 2008 and M arch 2009. Women with sufficient stored serum were randomly selected from among all women who delivered between A pril 2008 and M arch 2009. Serum vitamin D levels were determined using liquid chromatography coupled to tandem mass spectrometry. Vitamin D levels were analysed with respect to ethnicity (marking skin tone), calendar quartile, body mass index (BMI), trimester and parity. Deficiency was defined as <25 nmol L−1, insufficiency 25–75 nmol L−1 and adequacy >75 nmol L−1. Three hundred and forty‐six women were included and represented the total population regarding skin tone, quartile, BMI, gestation and parity. Overall, 18% [95% confidence interval (CI): 15–23%] of sample women had adequate vitamin D levels; 36% were deficient, 45% insufficient. Among women with dark skin, only 8% (95% CI: 5–12%) had adequate levels compared with 43% (95% CI: 33–53%) of those with light skin. Obese women were found have significantly lower vitamin D levels than non‐obese women. Vitamin D deficiency and insufficiency are prevalent year‐round among pregnant women in North West London, especially those with darker skin. Existing supplementation guidelines should be supported; however, other measures are required to improve status among all women.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1111/mcn.12014

Cites

39 of 39 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Approximately 95% of Japanese pregnant women have been reported to have 25(OH)D levels <50 nmol/L; corresponding figures in the UK and Latin America are 55% and 37%, respectively.

    “Approximately 95% of Japanese pregnant women have been reported to have 25(OH)D levels <50 nmol/L; the corresponding figures in the UK and Latin America have been reported to be 55% and 37%, respectively [51,52], a finding confirmed by a systematic review of global maternal and new born vitamin D status [53].”

    From Vitamin D and Autism Spectrum Disorder: A Literature Review (2016) · cites this paper as [51]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 1

  1. Dijkstra S.H., van Beek A., Janssen J.W., de Vleeschouwer L.H.M., Huysman W.A. &amp; van den Akker E.L.T. (2007) High prevalence of vitamin D deficiency in newborns of high risk mothers. Archives of Disease in Childhood 92 , 750-753. Available at: http://adc.bmj.com/content/92/9/ 750.full.pdf (Accessed 11 November 2012).

Cited by

Sorted by citations

Related

Authors
McAree, T., Jacobs, B., Manickavasagar, T., Velagala, S., Brennan, L., Bassett, P., Rainbow, S., & Blair, M.
Affiliations
  • London North West Healthcare NHS Trust (GB)
  • RNOH NHS Trust London UK
  • Imperial College London (GB)
  • Imperial College Healthcare NHS Trust (GB)
  • Statsconsultancy Ltd Amersham UK
ORCID
Venue
Maternal & Child Nutrition
Publisher
Wiley
Published
2012-12-11
Volume
9
Issue
1
Pages
23-30
ISSN
  • 1740-8695 (ISSN-L)
  • 1740-8709
DOI
10.1111/mcn.12014
PMC
PMC6860546
OpenAlex
W1498264251
Cited by
79
References
39
Citations by year
2026: 1 · 2025: 6 · 2024: 3 · 2023: 6 · 2022: 5 · 2021: 3 · 2020: 4 · 2019: 7 · 2018: 8 · 2017: 4 · 2016: 9 · 2015: 8 · 2014: 8 · 2013: 6
FWCI
5.08
Type
journal article
Language
en
Open access
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Maternal and Child Nutrition (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
Topics
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Vitamin D Research Studies
  • Health Sciences › Nursing › Nutrition and Dietetics › Vitamin K Research Studies
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutrition and Health Studies
Keywords
vitamin D deficiency, vitamin D insufficiency, pregnancy, serum 25-hydroxyvitamin D, prevalence, skin pigmentation, obesity, body mass index, parity, pregnancy trimesters, vitamin D supplementation, public health
MeSH terms
Adult, Female, Humans, London, Obesity, Parity, Pregnancy, Pregnancy Complications, Public Health, Retrospective Studies, Seasons, Skin Pigmentation, Vitamin D, Vitamin D Deficiency, Body Mass Index, Prevalence, Dietary Supplements

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review