Cited by 111Heavy metals in environmentHeavy Metals in PlantsPlant Stress Responses and Tolerance

Contrasting cadmium resistance strategies in two metallicolous populations of Arabidopsis halleri

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Corso, Massimiliano, Schvartzman, M. Sol, Guzzo, Flavia, Souard, Florence, Malkowski, Eugeniusz, Hanikenne, Marc, Verbruggen, Nathalie·2018·New Phytologist

Abstract

While cadmium (Cd) tolerance is a constitutive trait in the Arabidopsis halleri species, Cd accumulation is highly variable. Recent adaptation to anthropogenic metal stress has occurred independently within the genetic units of A. halleri and the evolution of different mechanisms involved in Cd tolerance and accumulation has been suggested. To gain a better understanding of the mechanisms underlying Cd tolerance and accumulation in A. halleri, ionomic inductively coupled plasma mass spectrometry (ICP-MS), transcriptomic (RNA sequencing) and metabolomic (high-performance liquid chromatography-mass spectrometry) profiles were analysed in two A. halleri metallicolous populations from different genetic units (PL22 from Poland and I16 from Italy). The PL22 and I16 populations were both hypertolerant to Cd, but PL22 hyperaccumulated Cd while I16 behaved as an excluder both in situ and when grown hydroponically. The observed hyperaccumulator vs excluder behaviours were paralleled by large differences in the expression profiles of transporter genes. Flavonoid-related transcripts and metabolites were strikingly more abundant in PL22 than in I16 shoots. The role of novel A. halleri candidate genes possibly involved in Cd hyperaccumulation or exclusion was supported by the study of corresponding A. thaliana knockout mutants. Taken together, our results are suggestive of the evolution of divergent strategies for Cd uptake, transport and detoxification in different genetic units of A. halleri.

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Crossref · 10.1111/nph.14948

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  • A. halleri shows species-wide Zn and Cd hypertolerance, with significant variation among its various populations.

    “In addition, A. halleri shows species-wide Zn and Cd hypertolerance, with significant variation among its various populations (Pauwels et al., 2006; Meyer et al., 2010; Corso et al., 2018).”

    From Plant hyperaccumulators: a state-of-the-art review on mechanism of heavy metal transport and sequestration (2025) · cites this paper as Corso et al., 2018

    The Abstract describes Cd tolerance as a constitutive trait of A. halleri, and the Introduction reports substantial variation in Cd tolerance among populations. The paper also reports high Zn tolerance in the two populations studied, but the passages do not establish species-wide Zn hypertolerance or significant variation in Zn tolerance among populations. (LLM, conf=0.87)

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Authors
Corso, M., Schvartzman, M. S., Guzzo, F., Souard, F., Malkowski, E., Hanikenne, M., & Verbruggen, N.
Affiliations
  • Université Libre de Bruxelles (BE)
  • InBioS‐PhytoSystems Functional Genomics and Plant Molecular Imaging University of Liège B‐4000 Liège Belgium
  • University of Verona (IT)
  • Centre National de la Recherche Scientifique (FR)
  • Department of Plant Physiology Faculty of Biology and Environmental Protection University of Silesia in Katowice 40‐032 Katowice Poland
  • University of Liège (BE)
Corresponding author
Verbruggen, Nathalie
Venue
New Phytologist
Publisher
Wiley
Published
2018-01-02
Volume
218
Issue
1
Pages
283-297
ISSN
  • 0028-646X (ISSN-L)
  • 1469-8137
OpenAlex
W2781649698
Cited by
110
References
78
Citations by year
2026: 7 · 2025: 8 · 2024: 16 · 2023: 15 · 2022: 11 · 2021: 15 · 2020: 17 · 2019: 14 · 2018: 6 · 2017: 1
FWCI
4.87
Type
journal article
Language
en
Open access
Locations
  • New Phytologist (publishedVersion)
  • PubMed (publishedVersion)
  • HAL (submittedVersion)
  • Dépôt institutionnel de l'Université libre de Bruxelles (Université Libre de Bruxelles) (submittedVersion)
  • ORBi (University of Liège) (submittedVersion, other-oa)
Funders
  • Fonds De La Recherche Scientifique - FNRS (PDR T.0206.13)
  • Université de Liège (SFRD‐12/03, SFRD-12/03)
Topics
  • Physical Sciences › Environmental Science › Pollution › Heavy metals in environment
  • Physical Sciences › Chemistry › Analytical Chemistry › Heavy Metals in Plants
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Stress Responses and Tolerance
Keywords
cadmium tolerance, cadmium hyperaccumulation, cadmium exclusion, Arabidopsis halleri, metal transporters, flavonoids, metal detoxification, metal uptake, candidate genes, genetic units
MeSH terms
Antioxidants, Cadmium, Flavonoids, Minerals, Models, Biological, Soil, Stress, Physiological, Genes, Plant, Arabidopsis, Gene Expression Regulation, Plant, Plant Shoots, Principal Component Analysis, Metabolomics, Transcriptome

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