The DOI matches its Crossref record; 94 of the 94 references it cites were found in a registry or an index.
Obesity and C‐reactive protein in various populations: a systematic review and meta‐analysis
Abstract
Summary: Obesity has been associated with elevated levels of C‐reactive protein (CRP), a marker of inflammation and predictor of cardiovascular risk. The objective of this systematic review and meta‐analysis was to estimate the associations between obesity and CRP according to sex, ethnicity and age. MEDLINE and EMBASE databases were searched through O ctober 2011. Data from 51 cross‐sectional studies that used body mass index (BMI), waist circumference (WC) or waist‐to‐hip ratio (WHR) as measure of obesity were independently extracted by two reviewers and aggregated using random‐effects models. The P earson correlation (r) for BMI and ln(CRP) was 0.36 (95% confidence interval [CI], 0.30–0.42) in adults and 0.37 (CI, 0.31–0.43) in children. In adults, r for BMI and ln(CRP) was greater in women than men by 0.24 (CI, 0.09–0.37), and greater in N orth A mericans/E uropeans than A sians by 0.15 (CI, 0–0.28), on average. In N orth A merican/E uropean children, the sex difference in r for BMI and ln(CRP) was 0.01 (CI, −0.08 to 0.06). Although limited to anthropometric measures, we found similar results when WC and WHR were used in the analyses. Obesity is associated with elevated levels of CRP and the association is stronger in women and N orth A mericans/E uropeans. The sex difference only emerges in adulthood.
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“Adipose tissue is an active endocrine organ that releases a variety of hormones and cytokines that contributes to CRP elevation (2).”
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Ellulu, M. S., Patimah, I., Khaza’ai, H., Rahmat, A., & Abed, Y. (2017) · Archives of Medical Science · doi:10.5114/aoms.2016.58928 · Cited by 1,982
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The double burden of malnutrition: aetiological pathways and consequences for health
Wells, J. C., Sawaya, A. L., Wibaek, R., Mwangome, M., Poullas, M. S., Yajnik, C. S., & Demaio, A. (2020) · The Lancet · doi:10.1016/s0140-6736(19)32472-9 · Cited by 993
Obesity, inflammation, and the gut microbiota
Cox, A. J., West, N. P., & Cripps, A. W. (2015) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(14)70134-2 · Cited by 869
Inflammation: Depression Fans the Flames and Feasts on the Heat
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Metadata
- Authors
- Choi, J., Joseph, L., & Pilote, L.
- Venue
- Obesity Reviews
- Publisher
- Wiley
- Published
- 2012-11-22
- Volume
- 14
- Issue
- 3
- Pages
- 232-244
- ISSN
- 1467-7881 (ISSN-L)
- 1467-789X
- OpenAlex
- W2109694442
- Cited by
- 655
- References
- 94
- FWCI
- 3.78
- Type
- journal article
- Language
- en
- Open access
- closed
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