Intermittently scanned continuous glucose monitoring is associated with high satisfaction but increased HbA1c and weight in well‐controlled youth with type 1 diabetes
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OBJECTIVE: We undertook a 24-month prospective observational single-center real-world trial to study impact of access to intermittently scanned continuous glucose monitoring (isCGM) on quality of life (QOL) and glycemic control of youth with type 1 diabetes (T1D). METHODS: Between September 2016 and November 2017, 138 children and adolescents with T1D were recruited. Demographic, metabolic, and QOL data were collected during 24 months of routine follow-up. Primary endpoint was the evolution of QOL, with secondary outcomes change in HbA1c, occurrence of acute diabetes complications, and school absenteeism. RESULTS: Ninety-two percent of participants found isCGM more user-friendly than capillary finger-stick tests and had high treatment satisfaction, without change in diabetes-specific QOL. HbA1c significantly increased from 7.2% (7.0-7.3) (55 mmol/mol [53-56]) at baseline to 7.6% (7.4-7.8) (60 mmol/mol [57-62]) at 12 months (P < .0001) and was unchanged up to 24 months. Overall increase was mainly driven by children with baseline HbA1c <7.0% (<53 mmol/mol). Additionally, BMI adjusted for age was higher at study end. In year before isCGM, 228 days per 100 patient-years of school absenteeism were reported, which dramatically decreased to 13 days per 100 patient-years (P = .016) after 24 months. Parents of children also reported less work absenteeism (P = .011). CONCLUSION: The use of isCGM by T1D pediatrics is associated with high treatment satisfaction and fewer days of school absence. However, increased HbA1c and weight may reflect a looser lifestyle, with less attention to diet and more avoidance of hypoglycemia. Intensive education specifically focusing on these points may mitigate these issues.
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In youth with type 1 diabetes, intermittently scanned CGM is associated with a slight increase in A1C and weight but a high user satisfaction rate.
“In an observational study in youth with type 1 diabetes, a slight increase in A1C levels and weight was seen, but the device was associated with a high user satisfaction rate (76).”
From 7. Diabetes Technology: Standards of Care in Diabetes—2025 (2025) · cites this paper as [76]
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- Authors
- Charleer, S., Gillard, P., Vandoorne, E., Cammaerts, K., Mathieu, C., & Casteels, K.
- Affiliations
- Universitair Ziekenhuis Leuven (BE)
- Corresponding author
- Casteels, Kristina
- Venue
- Pediatric Diabetes
- Publisher
- Wiley
- Published
- 2020-10-06
- Volume
- 21
- Issue
- 8
- Pages
- 1465-1474
- ISSN
- 1399-543X (ISSN-L)
- 1399-5448
- OpenAlex
- W3089320054
- Cited by
- 14
- References
- 57
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 3 · 2023: 1 · 2022: 4 · 2021: 3
- FWCI
- 1.51
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Pediatric Diabetes (publishedVersion)
- PubMed (publishedVersion)
- Lirias (submittedVersion, other-oa)
- VUBIR (Vrije Universiteit Brussel) (submittedVersion)
- Funders
- Abbott Laboratories
- Eli Lilly and Company
- AstraZeneca
- Sanofi
- European Foundation for the Study of Diabetes
- Fonds Wetenschappelijk Onderzoek
- KU Leuven
- Novo Nordisk
- Janssen Pharmaceuticals
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Diabetes and associated disorders
- Keywords
- intermittently scanned continuous glucose monitoring, type 1 diabetes, youth, glycemic control, HbA1c, quality of life, treatment satisfaction, school absenteeism, weight gain, diabetes self-management education
- MeSH terms
- Adolescent, Blood Glucose, Body Weight, Child, Child, Preschool, Diabetes Mellitus, Type 1, Female, Glycated Hemoglobin, Humans, Hypoglycemic Agents, Male, Prospective Studies, Quality of Life, Blood Glucose Self-Monitoring
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