The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.
Clinical and public health implications of periodontal and systemic diseases: An overview
Abstract
Severe periodontitis is defined by extensive loss of the tooth attachment apparatus. It is the sixth most common human disease and is estimated to affect 11.2% of the global adult population, hence representing a significant healthcare, social, and economic burden. Since the 1990s, multiple epidemiologic, experimental, and interventional studies have evidenced how periodontitis may also impact systemic health and it has been independently associated with the majority of chronic noncommunicable diseases. The evidence supporting these associations, mainly focusing on diabetes, pregnancy complications, and cardiovascular disease, was thoroughly reviewed in 2012 by an international consensus workshop. In the last 5 years, however, important advances have been made, not only in our understanding of the etiopathogenesis of periodontitis, or concerning the mounting evidence regarding the independent associations between periodontitis, diabetes, and cardiovascular disease, but also with many other systemic diseases including metabolic disease and obesity, rheumatoid arthritis, certain cancers, respiratory diseases, and cognitive disorders including Alzheimer's disease. This review describes these scientific advances by gathering together the existing evidence on the importance and relevance of the associations between periodontitis and many systemic diseases.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Vos, T., Abajobir, A. A., Abate, K. H., Abbafati, C., Abbas, K. M., Abd-Allah, F., Abdulkader, R. S., Abdulle, A. M., Abebo, T. A., Abera, S. F., et al. (2017) · The Lancet · doi:10.1016/s0140-6736(17)32154-2 · Cited by 13,220
Vos, T., Barber, R. M., Bell, B., Bertozzi-Villa, A., Biryukov, S., Bolliger, I., Charlson, F., Davis, A., Degenhardt, L., Dicker, D., et al. (2015) · The Lancet · doi:10.1016/s0140-6736(15)60692-4 · Cited by 6,414
Caton, J. G., Armitage, G., Berglundh, T., Chapple, I. L. C., Jepsen, S., Kornman, K. S., Mealey, B. L., Papapanou, P. N., Sanz, M., & Tonetti, M. S. (2018) · Journal of Periodontology · doi:10.1002/jper.18-0157 · Cited by 1,845
Self-citationPapapanou, P. N., Sanz, M., Buduneli, N., Dietrich, T., Feres, M., Fine, D. H., Flemmig, T. F., Garcia, R., Giannobile, W. V., Graziani, F., et al. (2018) · Journal of Clinical Periodontology · doi:10.1111/jcpe.12946 · Cited by 1,259
Self-citationChapple, I. L. C., Genco, R., & on behalf of working group 2 of the joint EFP/AAP workshop (2013) · Journal of Periodontology · doi:10.1902/jop.2013.1340011 · Cited by 852
Self-citationThe role of the microbiota in periodontal disease
Curtis, M. A., Diaz, P. I., & Van Dyke, T. E. (2020) · Periodontology 2000 · doi:10.1111/prd.12296 · Cited by 698
The role of inflammation and genetics in periodontal disease
Loos, B. G., & Van Dyke, T. E. (2020) · Periodontology 2000 · doi:10.1111/prd.12297 · Cited by 612
Chapple, I. L. C., Genco, R., & working group 2 of the joint EFP/AAP workshop (2013) · Journal of Clinical Periodontology · doi:10.1111/jcpe.12077 · Cited by 446
Self-citationMechanisms underlying the association between periodontitis and atherosclerotic disease
Schenkein, H. A., Papapanou, P. N., Genco, R., & Sanz, M. (2020) · Periodontology 2000 · doi:10.1111/prd.12304 · Cited by 440
Self-citationTonetti, M. S., Van Dyke, T. E., & working group 1 of the joint EFP/AAP workshop (2013) · Journal Of Clinical Periodontology · doi:10.1111/jcpe.12089 · Cited by 395
Cited by
Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities
Hajishengallis, G., & Chavakis, T. (2021) · Nature Reviews Immunology · doi:10.1038/s41577-020-00488-6 · Cited by 1,871
The oral microbiome: diversity, biogeography and human health
Baker, J. L., Mark Welch, J. L., Kauffman, K. M., McLean, J. S., & He, X. (2024) · Nature Reviews Microbiology · doi:10.1038/s41579-023-00963-6 · Cited by 661
Association between periodontitis and severity of COVID‐19 infection: A case–control study
Marouf, N., Cai, W., Said, K. N., Daas, H., Diab, H., Chinta, V. R., Hssain, A. A., Nicolau, B., Sanz, M., & Tamimi, F. (2021) · Journal Of Clinical Periodontology · doi:10.1111/jcpe.13435 · Cited by 380
Maladaptive innate immune training of myelopoiesis links inflammatory comorbidities
Li, X., Wang, H., Yu, X., Saha, G., Kalafati, L., Ioannidis, C., Mitroulis, I., Netea, M. G., Chavakis, T., & Hajishengallis, G. (2022) · Cell · doi:10.1016/j.cell.2022.03.043 · Cited by 328
The oral–gut microbiome axis in health and disease
Kunath, B. J., De Rudder, C., Laczny, C. C., Letellier, E., & Wilmes, P. (2024) · Nature Reviews Microbiology · doi:10.1038/s41579-024-01075-5 · Cited by 316
Metadata
- Authors
- Genco, R. J., & Sanz, M.
- Venue
- Periodontology 2000
- Publisher
- Wiley
- Published
- 2020-05-08
- Volume
- 83
- Issue
- 1
- Pages
- 7-13
- ISSN
- 0906-6713 (ISSN-L)
- 1600-0757
- OpenAlex
- W3022548569
- Cited by
- 665
- References
- 30
- FWCI
- 57.59
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Clinical and public health implications of periodontal and systemic diseases: An overview. https://app.cochat.ai/papers/10.1111/prd.12344
- The paper
- Genco, R. J., & Sanz, M. (2020). Clinical and public health implications of periodontal and systemic diseases: An overview. Periodontology 2000. https://doi.org/10.1111/prd.12344
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
