Cited by 16Muscle metabolism and nutritionSports Performance and TrainingExercise and Physiological Responses

Role of Protein and Hydrolysates before Exercise

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Tipton, Kevin D.·2007·International Journal of Sport Nutrition and Exercise Metabolism

Abstract

Adaptations to exercise training are determined by the response of metabolic and molecular mechanisms that determine changes in proteins. The type, intensity, and duration of exercise, as well as nutrition, determine these responses. The importance of protein, in the form of intact proteins, hydrolysates, or free amino acids, for exercise adaptations is widely recognized. Exercise along with protein intake results in accumulation of proteins that influence training adaptations. The total amount of protein necessary to optimize adaptations is less important than the type of protein, timing of protein intake, and the other nutrients ingested concurrently with the protein. Acute metabolic studies offer an important tool to study the responses of protein balance to various exercise and nutritional interventions. Recent studies suggest that ingestion of free amino acids plus carbohydrates before exercise results in a superior anabolic response to exercise than if ingested after exercise. However, the difference between pre- and post exercise ingestion of intact proteins is not apparent. Thus, the anabolic response to exercise plus protein ingestion seems to be determined by the interaction of timing of nutrient intake in relation to exercise and the nutrients ingested. More research is necessary to delineate the optimal combination of nutrients and timing for various types of training adaptations. Protein and amino acid intake have long been deemed important for athletes and exercising individuals. Olympic athletes, from the legendary Milo to many in the 1936 Berlin games, reportedly consumed large amounts of protein. Modern athletes may consume slightly less than these historical figures, yet protein is deemed extremely important by most. Protein is important as a source of amino acids for recovery from exercise and repair of damaged tissues, as well as for adaptations to exercise training, such as muscle hypertrophy and mitochondrial biogenesis.

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Crossref · 10.1123/ijsnem.17.s1.s77

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  • Intact protein supplements such as egg, whey, casein, beef, soy and whole milk can evoke an anabolic response similar or greater in magnitude to free form amino acids, assuming ingestion of equal EAA amounts.

    “it is now clear that intact protein supplements such as egg, whey, casein, beef, soy and even whole milk can evoke an anabolic response that can be similar or greater in magnitude to free form amino acids, assuming ingestion of equal EAA amounts [62–64].”
  • In younger subjects, ingestion of 20-30 g of any high biological value protein before or after resistance exercise appears to be sufficient to maximally stimulate MPS.

    “In younger subjects, the ingestion of 20–30 g of any high biological value protein before or after resistance exercise appears to be sufficient to maximally stimulate MPS [21, 64].”

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Authors
Tipton, K. D.
Affiliations
University of Birmingham (GB)
Corresponding author
Tipton, Kevin D.
Venue
International Journal of Sport Nutrition and Exercise Metabolism
Published
2007-02
Volume
17
Issue
s1
Pages
S77-S86
ISSN
  • 1526-484X (ISSN-L)
  • 1543-2742
OpenAlex
W2161536450
Cited by
16
References
10
Citations by year
2023: 2 · 2020: 1 · 2017: 1 · 2015: 1 · 2014: 1 · 2012: 1
FWCI
0.22
Type
journal article
Language
en
Open access
Locations
  • International Journal of Sport Nutrition and Exercise Metabolism (publishedVersion)
  • PubMed (publishedVersion)
  • Stirling Online Research Repository (University of Stirling) (submittedVersion, public-domain)
  • University of Birmingham Research Portal (University of Birmingham) (submittedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
  • Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
  • Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
Keywords
protein intake, protein hydrolysates, free amino acids, pre-exercise nutrition, exercise adaptation, protein balance, muscle hypertrophy, mitochondrial biogenesis, muscle recovery, anabolic response
MeSH terms
Amino Acids, Dietary Proteins, Food, Humans, Muscle Proteins, Protein Hydrolysates, Exercise, Muscle, Skeletal

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