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The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.

What Is in Your Beet Juice? Nitrate and Nitrite Content of Beet Juice Products Marketed to Athletes

Gallardo, Edgar J., Coggan, Andrew R.·2019·International Journal of Sport Nutrition and Exercise Metabolism

Abstract

Consumption of beetroot juice (BRJ) supplements has become popular among athletes because beets tend to be rich in nitrate (NO 3−), which can enhance exercise performance by increasing nitric oxide production. The NO 3− content of beets can vary significantly, however, making it difficult to know how much NO 3− any product actually contains. Samples from 45 different lots of 24 different BRJ products from 21 different companies were therefore analyzed for NO 3− (and nitrite [NO 2−]) concentration using high-performance liquid chromatography. The NO 3− and NO 2− content (i.e., amount per serving) was then calculated based on either (a) the manufacturer’s recommended serving size (for prepackaged/single dose products) or (b) as used in previous studies, a volume of 500 ml (for BRJ sold in bulk containers). There was moderate-to-large variability in NO 3− content between samples of the same product, with a mean coefficient of variation of 30% ± 26% (range 2–83%). There was even greater variability between products, with a ∼50-fold range in NO 3− content between the lowest and highest. Only five products consistently provided ≥5 mmol of NO 3−/serving, which seems to be the minimal dose required to enhance exercise performance in most individuals. NO 2− contents were generally low (i.e., ≤0.5% compared with NO 3−), although two products contained 10% and 14%. The results of this study may be useful to athletes and their support staff contemplating which (if any) BRJ product to utilize. These data may also offer insight into variability in the literature with respect to the effects of BRJ on exercise performance.

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Crossref · 10.1123/ijsnem.2018-0223

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Citations

Cites

Research works printed but not linked: 14

  1. Clifford, T., Howatson, G., West, D.J., & Stevenson, E.J. (2017). Beetroot juice is more beneficial than sodium nitrate for attenuating muscle pain after strenuous eccentric-bias exercise. Applied Physiology, Nutrition, and Metabolism, 42, 1185–1191. PubMed ID: 28719765 doi:10.1139/apnm-2017-0238 · DOI
  2. Coggan, A.R., Broadstreet, S.R., Mahmood, K., Mikhalkova, D., Madigan, M., Bole, I., … Peterson, L.R. (2018a). Dietary nitrate increases VO2peak and performance but does not alter ventilation or efficiency in patients with heart failure with reduced ejection fraction. Journal of Cardiac Failure, 24, 65–73. PubMed ID: 28916479 doi:10.1016/j.cardfail.2017.09.004 · DOI
  3. Coggan, A.R., Leibowitz, J.L., Anderson Spearie, C., Kadkhodayan, A., Thomas, D.P., Ramamurthy, S., … Peterson, L.R. (2015a). Acute dietary nitrate intake improves muscle contractile function in patients with heart failure: A double-blind, placebo-controlled, randomized trial. Circulation: Heart Failure, 8, 914–920. PubMed ID: 26179185 doi:10.1161/CIRCHEARTFAILURE.115.002141 · DOI · Paper page
  4. Coggan, A.R., Leibowitz, J.L., Kadkhodayan, A., Thomas, D.T., Ramamurthy, S., Spearie, C.A., … Peterson, L.R. (2015b). Effect of acute dietary nitrate intake on knee extensor speed and power in healthy men and women. Nitric Oxide, 48, 16–21. PubMed ID: 25199856 doi:10.1016/j.niox.2014.08.014 · DOI · Paper page
  5. Corleto, K.A., Singh, J., Jayaprakasha, G.K., & Patil, B.S. (2018). Storage stability of dietary nitrate and phenolic compounds in beetroot (Beta vulgaris) and arugula (Eruca sativa) juices. Journal of Food Science, 83, 1237–1248. PubMed ID: 29660828 doi:10.1111/1750-3841.14129 · DOI
  6. Hoon, M.W., Fornusek, C., Chapman, P.G., & Johnson, N.A. (2015). The effect of nitrate supplementation on muscle contraction in healthy adults. European Journal of Sport Science, 8, 712–719. PubMed ID: 26681629 doi:10.1080/17461391.2015.1053418 · DOI
  7. Justice, J.N., Johnson, L.C., DeVan, A.E., Cruickshank-Quinn, C., Reisdorph, N., Bassett, C.J., … Seals, D.R. (2015). Improved motor and cognitive performance with sodium nitrite supplementation is related to small metabolite signatures: A pilot trial in middle-aged and older adults. Aging, 7, 1004–1021. PubMed ID: 26626856 doi:10.18632/aging.100842 · DOI
  8. Kharti, J., Mills, C.E., Maskell, P., Odongerel, C., & Webb, A.J. (2017). It is rocket science—Why dietary nitrate is hard to ‘beet’! Part I: Twists and turns in the realization of the nitrate–nitrite–NO pathway. British Journal of Clinical Pharmacology, 83, 129–139. PubMed ID: 26896747 doi:10.1111/bcp.12913 · DOI
  9. McDonagh, S.T.J., Wylie, L.J., Webster, J.M.A., Vanhatalo, A., & Jones, A.M. (2018). Influence of dietary nitrate food forms on nitrate metabolism and blood pressure in healthy normotensive adults. Nitric Oxide, 72, 66–74. PubMed ID: 29223585 doi:10.1016/j.niox.2017.12.001 · DOI
  10. Oskarsson, J., & McGawley, K. (2018). No individual or combined effects of caffeine and beetroot-juice supplementation during submaximal or maximal running. Applied Physiology, Nutrition, and Metabolism, 43, 697–703. PubMed ID: 29444414 doi:10.1139/apnm-2017-0547 · DOI · Paper page
  11. Thompson, C., Vanhatalo, A., Kadach, S, Wylie, L.J., Fulford, J., Ferguson, S.K., … Jones, A.M. (2018). Discrete physiological effects of beetroot juice and potassium nitrate supplementation following 4-wk sprint interval training. Journal of Applied Physiology, 124, 1519–1528. PubMed ID: 29494294 doi:10.1152/japplphysiol.00047.2018 · DOI · Paper page
  12. Troutman, A.D., Gallardo, E.J., Brown, M.B., & Coggan, A.R. (2018). Measurement of nitrate and nitrite in biopsy-sized muscle samples using HPLC. Journal of Applied Physiology. Advance online publication. doi:10.1152/japplphysiol.00625.2018 · DOI
  13. Van De Walle, G.P., & Vukovich, M.D. (2018). The effect of nitrate supplementation on exercise tolerance and performance: A systematic review and meta-analysis. The Journal of Strength and Conditioning Research, 32, 1796–1808. PubMed ID: 29786633 doi:10.1519/JSC0000000000002046 · DOI
  14. Wruss, J., Waldenburger, G., Huemer, S., Uygun, P., Lanzerstorfer, P., Müller, U., … Weghuber, J. (2015). Composition characteristics of commercial beetroot products and beetroot juice prepared from seven beetroot varieties grown in Upper Austria. Journal of Food Composition and Analysis, 42, 46–55.

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Metadata

Authors
Gallardo, E. J., & Coggan, A. R.
Affiliations
Indiana University Purdue University Indianapolis
Venue
International Journal of Sport Nutrition and Exercise Metabolism
Published
2019-07-01
Volume
29
Issue
4
Pages
345-349
ISSN
  • 1526-484X
  • 1543-2742
Cited by
56
References
9

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