The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.
Daily Probiotic’s (Lactobacillus casei Shirota) Reduction of Infection Incidence in Athletes
Open accessAbstract
The purpose of this study was to examine the effects of a probiotic supplement during 4 mo of winter training in men and women engaged in endurance-based physical activities on incidence of upper respiratory-tract infections (URTIs) and immune markers. Eighty-four highly active individuals were randomized to probiotic ( n = 42) or placebo ( n = 42) groups and, under double-blind procedures, received probiotic (PRO: Lactobacillus casei Shirota [LcS]) or placebo (PLA) daily for 16 wk. Resting blood and saliva samples were collected at baseline and after 8 and 16 wk. Weekly training and illness logs were kept. Fifty-eight subjects completed the study ( n = 32 PRO, n = 26 PLA). The proportion of subjects on PLA who experienced 1 or more weeks with URTI symptoms was 36% higher than those on PRO (PLA 0.90, PRO 0.66; p = .021). The number of URTI episodes was significantly higher ( p < .01) in the PLA group (2.1 ± 1.2) than in the PRO group (1.2 ± 1.0). Severity and duration of symptoms were not significantly different between treatments. Saliva IgA concentration was higher on PRO than PLA, significant treatment effect F (1, 54) = 5.1, p = .03; this difference was not evident at baseline but was significant after 8 and 16 wk of supplementation. Regular ingestion of LcS appears to be beneficial in reducing the frequency of URTI in an athletic cohort, which may be related to better maintenance of saliva IgA levels during a winter period of training and competition.
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“Similarly, Gleeson et al. [60] examined the effects of Lactobacillus casei Shirota during 4 months of winter training in endurance-based recreational athletes and observed a significant reduction in URTIs compared to placebo. In addition, salivary IgA concentration was significantly higher in those consuming the probiotic.”
From International Society of Sports Nutrition Position Stand: Probiotics (2019) · cites this paper as [60]
In the citing paper
“Probiotic bacteria, particularly the gram-positive genera Lactobacillus and Bifidobacterium species, are known to modify GI microbiota [17,18,19], and have been shown to reduce GI episode severity [20] and respiratory tract infections commonly associated with training [21].”
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Maughan, R. J., Burke, L. M., Dvorak, J., Larson-Meyer, D. E., Peeling, P., Phillips, S. M., Rawson, E. S., Walsh, N. P., Garthe, I., Geyer, H., et al. (2018) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.2018-0020 · Cited by 540
Thirty Years of Lactobacillus rhamnosus GG
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Metadata
- Authors
- Gleeson, M., Bishop, N. C., Oliveira, M., & Tauler, P.
- Affiliations
- Loughborough University (GB)
- Venue
- International Journal of Sport Nutrition and Exercise Metabolism
- Publisher
- Human Kinetics
- Published
- 2011-02
- Volume
- 21
- Issue
- 1
- Pages
- 55-64
- ISSN
- 1526-484X (ISSN-L)
- 1543-2742
- OpenAlex
- W2114489487
- Cited by
- 239
- References
- 45
- Citations by year
- 2026: 9 · 2025: 11 · 2024: 13 · 2023: 12 · 2022: 25 · 2021: 19 · 2020: 19 · 2019: 21 · 2018: 20 · 2017: 12 · 2016: 15 · 2015: 15 · 2014: 8 · 2013: 20 · 2012: 14
- FWCI
- 21.04
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- International Journal of Sport Nutrition and Exercise Metabolism (publishedVersion)
- PubMed (publishedVersion)
- Loughborough University Institutional Repository (Loughborough University) (submittedVersion, cc-by-nc-nd)
- Loughborough University Research Repository (Loughborough University) (submittedVersion, cc-by-nc-nd)
- Funders
- Yakult Honsha
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Health Sciences › Medicine › Physiology (medical) › Exercise and Physiological Responses
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pediatric health and respiratory diseases
- Keywords
- probiotics, Lactobacillus casei Shirota, upper respiratory tract infection, athletes, endurance training, winter training, saliva IgA, immunological markers, infection incidence, immune function
- MeSH terms
- Adolescent, Adult, Double-Blind Method, Female, Humans, Immunoglobulins, Lacticaseibacillus casei, Male, Middle Aged, Respiratory Tract Infections, Saliva, Lymphocyte Subsets, Cytokines, Immunity, Mucosal, Probiotics, Gastrointestinal Tract, Young Adult, Athletes
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