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Sigma-2 Receptors Play a Role in Cellular Metabolism: Stimulation of Glycolytic Hallmarks by CM764 in Human SK-N-SH Neuroblastoma

Nicholson, Hilary, Mesangeau, Christophe, McCurdy, Christopher R., Bowen, Wayne D.·2016·The Journal of Pharmacology and Experimental Therapeutics
DOI 10.1124/jpet.115.228387
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  • S2R activity was initially localized to a ~20 kDa membrane protein and first thought to be progesterone receptor membrane component 1 (PGRMC1).

    “S2R activity was initially localized to a ~20 kDa membrane protein [51,52] and first thought to be progesterone receptor membrane component 1 (PGRMC1), based on mass spectrophotometry identification following an immunoaffinity pull down with an irreversible S2R ligand binder WC-11, physiochemical properties, and pharmacological evidence [53,54].”

    From Sigma-2 Receptors—From Basic Biology to Therapeutic Target: A Focus on Age-Related Degenerative Diseases (2023) · cites this paper as [54]

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Research works printed but not linked: 44

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  17. Hellewell, 1994, Rat liver and kidney contain high densities of sigma 1 and sigma 2 receptors: characterization by ligand binding and photoaffinity labeling, Eur J Pharmacol, 268, 9, 10.1016/0922-4106(94)90115-5 · DOI · Paper page
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  20. Kaushal, 2011, Synthesis and pharmacological evaluation of 6-acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79), a cocaine antagonist, in rodents, AAPS J, 13, 336, 10.1208/s12248-011-9274-9 · DOI
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Metadata

Authors
Nicholson, H., Mesangeau, C., McCurdy, C. R., & Bowen, W. D.
Venue
The Journal of Pharmacology and Experimental Therapeutics
Publisher
Elsevier BV
Published
2016-02
Volume
356
Issue
2
Pages
232-243
ISSN
0022-3565
DOI
10.1124/jpet.115.228387
Cited by
22
References
0
Language
en
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