Untranslated Region-Dependent Exclusive Expression of High-Sensitivity Subforms of α4β2 and α3β2 Nicotinic Acetylcholine Receptors

Nicotinic binding in rat brain: autoradiographic comparison of [3H]acetylcholine, [3H]nicotine, and [125I]-alpha-bungarotoxin

Clarke, P. B. S., Schwartz, R., Paul, S. M., Cb, P., & Pert, A. (1985) · Journal of Neuroscience · doi:10.1523/jneurosci.05-05-01307.1985 · Cited by 1,037 · see citing works

Neuronal nicotinic receptors: from structure to pathology

Gotti, C., & Clementi, F. (2004) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2004.09.006 · Cited by 970 · see citing works

A subtype of nicotinic cholinergic receptor in rat brain is composed of alpha 4 and beta 2 subunits and is up-regulated by chronic nicotine treatment.

Flores, C. M., Rogers, S. W., Pabreza, L. A., Wolfe, B. B., & Kellar, K. J. (1992) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)08832-7 · Cited by 880 · see citing works

Upstream Open Reading Frames as Regulators of mRNA Translation

Morris, D. R., & Geballe, A. P. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.23.8635-8642.2000 · Cited by 736 · see citing works

Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. I. Pharmacological and functional evidence for distinct structural subtypes.

Alkondon, M., & Albuquerque, E. X. (1993) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)38283-2 · Cited by 554 · see citing works

Subunit Composition of Functional Nicotinic Receptors in Dopaminergic Neurons Investigated with Knock-Out Mice

Champtiaux, N., Gotti, C., Cordero‐Erausquin, M., David, D. J. P., Przybylski, C., Léna, C., Clementi, F., Moretti, M., Rossi, F., Novère, N. G. L., et al. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-21-07820.2003 · Cited by 509 · see citing works

Translational control by the 3′-UTR: the ends specify the means

Mazumder, B., Seshadri, V., & Fox, P. L. (2003) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(03)00002-1 · Cited by 506 · see citing works

Alternate stoichiometries of α4β2 nicotinic acetylcholine receptors

Nelson, M. E., Kuryatov, A., Choi, C. H., Zhou, Y., & Lindstrom, J. (2003) · Molecular Pharmacology · doi:10.1124/mol.63.2.332 · Cited by 422 · see citing works

Pharmacological Characterization of Recombinant Human Neuronal Nicotinic Acetylcholine Receptors hα2β2, hα2β4, hα3β2, hα3β4, hα4β2, hα4β4 and hα7 Expressed in Xenopus Oocytes

Chavez-Noriega, L. E., Crona, J. H., Washburn, M. S., Urrutia, A., Elliott, K. J., & Johnson, E. C. (1997) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)36376-1 · Cited by 405 · see citing works

Pharmacological characterization of recombinant human neuronal nicotinic acetylcholine receptors h alpha 2 beta 2, h alpha 2 beta 4, h alpha 3 beta 2, h alpha 3 beta 4, h alpha 4 beta 2, h alpha 4 beta 4 and h alpha 7 expressed in Xenopus oocytes.

Chavez-Noriega, L. E., Crona, J. H., Washburn, M. S., Urrutia, A., Elliott, K. J., & Johnson, E. C. (1997) · PubMed · Cited by 392 · see citing works

Chronic Exposure to Nicotine Upregulates the Human α4β2 Nicotinic Acetylcholine Receptor Function

Buisson, B., & Bertrand, D. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-06-01819.2001 · Cited by 361 · see citing works

Developmental regulation of nicotinic ACh receptor subunit mRNAs in the rat central and peripheral nervous systems

Zoli, M., Novère, N. G. L., Hill, J. A., & Changeux, J. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-03-01912.1995 · Cited by 338 · see citing works

Comparative pharmacology of epibatidine: a potent agonist for neuronal nicotinic acetylcholine receptors.

Gerzanich, V., Peng, X.-D., Wang, F., Wells, G. B., Anand, R., Fletcher, S. R., & Lindstrom, J. M. (1995) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)10533-6 · Cited by 290 · see citing works

Bringing the role of mRNA decay in the control of gene expression into focus

Wilusz, C. J., & Wilusz, J. (2004) · Trends in Genetics · doi:10.1016/j.tig.2004.07.011 · Cited by 268 · see citing works

Partial agonist properties of cytisine on neuronal nicotinic receptors containing the beta 2 subunit

Papke, R. L., & Heinemann, S. F. (1994) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)09896-7 · Cited by 259 · see citing works

Mutation Causing Autosomal Dominant Nocturnal Frontal Lobe Epilepsy Alters Ca2+Permeability, Conductance, and Gating of Human α4β2 Nicotinic Acetylcholine Receptors

Kuryatov, A., Gerzanich, V., Nelson, M. E., Olale, F., & Lindstrom, J. M. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-23-09035.1997 · Cited by 227 · see citing works

Four Pharmacologically Distinct Subtypes of α4β2 Nicotinic Acetylcholine Receptor Expressed in Xenopus laevisOocytes

Zwart, R., & Vijverberg, H. P. M. (1998) · Molecular Pharmacology · doi:10.1124/mol.54.6.1124 · Cited by 215 · see citing works

Structural and Pharmacological Characterization of the Major Brain Nicotinic Acetylcholine Receptor Subtype Stably Expressed in Mouse Fibroblasts

Whiting, P. J., Schoepfer, R., Lindström, J., & Priestley, T. (1991) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)15355-8 · Cited by 200 · see citing works

The nicotinic acetylcholine receptor subtypes and their function in the hippocampus and cerebral cortex

Alkondon, M., & Albuquerque, E. X. (2004) · Progress in brain research · doi:10.1016/s0079-6123(03)45007-3 · Cited by 197 · see citing works

Human α4β2 Neuronal Nicotinic Acetylcholine Receptor in HEK 293 Cells: A Patch-Clamp Study

Buisson, B., Gopalakrishnan, M., Arnerić, S. P., Sullivan, J. P., & Bertrand, D. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-24-07880.1996 · Cited by 183 · see citing works

Stable expression, pharmacologic properties and regulation of the human neuronal nicotinic acetylcholine alpha 4 beta 2 receptor.

Gopalakrishnan, M., Monteggia, L. M., Anderson, D. J., Molinari, E. J., Piattoni-Kaplan, M., Donnelly-Roberts, D., Arneric, S. P., & Sullivan, J. P. (1996) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)12264-7 · Cited by 178 · see citing works

Point mutant mice with hypersensitive α4 nicotinic receptors show dopaminergic deficits and increased anxiety

Labarca, C., Schwarz, J., Deshpande, P., Schwarz, S., Nowak, M. W., Fonck, C., Nashmi, R., Kofuji, P., Dang, H., Shi, W., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.041582598 · Cited by 177 · see citing works

Human α4β2 Acetylcholine Receptors Formed from Linked Subunits

Zhou, Y., Nelson, M. E., Kuryatov, A., Choi, C., Cooper, J., & Lindstrom, J. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-27-09004.2003 · Cited by 174 · see citing works

Chronic Nicotine Exposure Differentially Affects the Function of Human α3, α4, and α7 Neuronal Nicotinic Receptor Subtypes

Olale, F., Gerzanich, V., Kuryatov, A., Wang, F., & Lindstrom, J. M. (1997) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)37064-8 · Cited by 174 · see citing works

Chronic nicotine exposure differentially affects the function of human alpha3, alpha4, and alpha7 neuronal nicotinic receptor subtypes.

Olale, F., Gerzanich, V., Kuryatov, A., Wang, F., & Lindstrom, J. M. (1997) · PubMed · Cited by 172 · see citing works

Activation and blocking of neuronal nicotinic acetylcholine receptor reconstituted in Xenopus oocytes.

Bertrand, D., Ballivet, M., & Rungger, D. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.5.1993 · Cited by 158 · see citing works

The C Terminus of the Human Nicotinic α4β2 Receptor Forms a Binding Site Required for Potentiation by an Estrogenic Steroid

Paradiso, K. G., Zhang, J., & Steinbach, J. H. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-17-06561.2001 · Cited by 144 · see citing works

Neuronal nicotinic acetylcholine receptor β‐subunit is coded for by the cDNA clone α4

Whiting, P. J., Esch, F. S., Shimasaki, S., & Lindstrom, J. M. (1987) · FEBS Letters · doi:10.1016/0014-5793(87)80272-7 · Cited by 134 · see citing works

Two pharmacologically distinct components of nicotinic receptor-mediated rubidium efflux in mouse brain require the beta2 subunit.

Marks, M. J., Whiteaker, P., Calcaterra, J., Stitzel, J. A., Bullock, A. E., Grady, S. R., Picciotto, M. R., Changeux, J., & Collins, A. C. (1999) · PubMed · Cited by 126 · see citing works

Nicotinic receptor function determined by stimulation of rubidium efflux from mouse brain synaptosomes.

Marks, M. J., Farnham, D. A., Grady, S. R., & Collins, A. C. (1993) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)10175-4 · Cited by 112 · see citing works

Potentiation of Human α4β2 Neuronal Nicotinic Acetylcholine Receptor by Estradiol

Curtis, L., Buisson, B., Bertrand, S., & Bertrand, D. (2002) · Molecular Pharmacology · doi:10.1124/mol.61.1.127 · Cited by 94 · see citing works

Knock-out and Knock-in Mice to Investigate the Role of Nicotinic Receptors in the Central Nervous System

Champtiaux, N., & Changeux, J. (2002) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/1568007023339247 · Cited by 88 · see citing works

Human α 7 nicotinic acetylcholine receptor responses to novel ligands

Briggs, C. A., McKenna, D. G., & Piattina-kaplan, M. (1995) · Neuropharmacology · doi:10.1016/0028-3908(95)00028-5 · Cited by 88 · see citing works

Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. III. Agonist actions of the novel alkaloid epibatidine and analysis of type II current.

Alkondon, M., & Albuquerque, E. X. (1995) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)10528-4 · Cited by 88 · see citing works

Subsets of acetylcholine-stimulated 86Rb+ efflux and [125I]-epibatidine binding sites in C57BL/6 mouse brain are differentially affected by chronic nicotine treatment

Marks, M. J., Rowell, P. P., Cao, J., Grady, S. R., McCallum, S. E., & Collins, A. C. (2004) · Neuropharmacology · doi:10.1016/j.neuropharm.2004.02.009 · Cited by 81 · see citing works

Two Pharmacologically Distinct Components of Nicotinic Receptor-Mediated Rubidium Efflux in Mouse Brain Require the β2 Subunit

Marks, M. J., Whiteaker, P., Calcaterra, J., Stitzel, J. A., Bullock, A. E., Grady, S. R., Picciotto, M. R., Changeux, J.-P., & Collins, A. C. (1999) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)38240-0 · Cited by 79 · see citing works

Characterization of the recombinant human neuronal nicotinic acetylcholine receptors α3β2 and α4β2 stably expressed in HEK293 cells

Chavez-Noriega, L. E., Gillespie, A. J., Stauderman, K. A., Crona, J. H., Claeps, B. O., Elliott, K. J., Reid, R. T., Rao, T. S., Veliçelebi, G., Harpold, M. M., et al. (2000) · Neuropharmacology · doi:10.1016/s0028-3908(00)00134-9 · Cited by 73 · see citing works

Ligand Binding and Activation of Rat Nicotinic α4β2 Receptors Stably Expressed in HEK293 Cells

Sabey, K., Paradiso, K. G., Zhang, J., & Steinbach, J. H. (1999) · Molecular Pharmacology · doi:10.1124/mol.55.1.58 · Cited by 66 · see citing works

Activity of cytisine and its brominated isosteres on recombinant human α7, α4β2 and α4β4 nicotinic acetylcholine receptors

Houlihan, L. M., Slater, Y., Guerra, D. L., Peng, J., Kuo, Y., Lukas, R. J., Cassels, B. K., & Bermúdez, I. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00481.x · Cited by 64 · see citing works

The Activation and Inhibition of Human Nicotinic Acetylcholine Receptor by RJR‐2403 Indicate a Selectivity for the α4β2 Receptor Subtype

Papke, R. L., Webster, J. C., Lippiello, P. M., Bencherif, M., & Francis, M. M. (2000) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2000.0750204.x · Cited by 63 · see citing works

Ethanol-Nicotine Interactions at alpha-Bungarotoxin-Insensitive Nicotinic Acetylcholine Receptors in Rat Cortical Neurons

Marszalec, W., Aistrup, G. L., & Narahashi, T. (1999) · Alcoholism Clinical and Experimental Research · doi:10.1097/00000374-199903000-00009 · Cited by 63 · see citing works

Knockout and knockin mice to investigate the role of nicotinic receptors in the central nervous system

Champtiaux, N., & Changeux, J. (2004) · Progress in brain research · doi:10.1016/s0079-6123(03)45016-4 · Cited by 53 · see citing works

α3, β2, and β4 Form Heterotrimeric Neuronal Nicotinic Acetylcholine Receptors in Xenopus Oocytes

Colquhoun, L. M., & Patrick, J. W. (1997) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1997.69062355.x · Cited by 49 · see citing works

Multiple components in the agonist concentration–response relationships of neuronal nicotinic acetylcholine receptors

Covernton, P. J. O., & Connolly, J. G. (2000) · Journal of Neuroscience Methods · doi:10.1016/s0165-0270(99)00185-5 · Cited by 47 · see citing works

Inhibition of nicotinic acetylcholine receptors by bis (2,2,6,6-tetramethyl- 4-piperidinyl) sebacate (Tinuvin 770), an additive to medical plastics.

Papke, R. L., Craig, A. G., & Heinemann, S. (1994) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)39002-6 · Cited by 47 · see citing works

Modulation by estrogens and xenoestrogens of recombinant human neuronal nicotinic receptors

Nakazawa, K., & Ohno, Y. (2001) · European Journal of Pharmacology · doi:10.1016/s0014-2999(01)01389-9 · Cited by 34 · see citing works

Comparison of the binding of nicotinic agonists to receptors from human and rat cerebral cortex and from chick brain (α4β2) transfected into mouse fibroblasts with ion channel activity

COURT, J. A., Perry, E. K., Spurden, D., Lloyd, S. R., Gillespie, J., Whiting, P. J., & Barlow, R. B. (1994) · Brain Research · doi:10.1016/0006-8993(94)91721-3 · Cited by 31 · see citing works

High Throughput Electrophysiology Using a Fully Automated, Multiplexed Recording System

Trumbull, J. D., Maslana, E. S., McKenna, D. G., Nemcek, T. A., Niforatos, W., Pan, J., Parihar, A. S., Shieh, C., Wilkins, J. A., Briggs, C. A., et al. (2003) · Receptors and Channels · doi:10.1080/10606820308252 · Cited by 31 · see citing works

Roles for Nicotinic Acetylcholine Receptor Subunit Large Cytoplasmic Loop Sequences in Receptor Expression and Function

Kuo, Y., Xu, L., Eaton, J. B., Zhao, L., Wu, J., & Lukas, R. J. (2005) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.105.084954 · Cited by 29 · see citing works

The mouse Chrna4 A529T polymorphism alters the ratio of high to low affinity α4β2 nAChRs

Kim, H., Flanagin, B. A., Qin, C., Macdonald, R. L., & Stitzel, J. A. (2003) · Neuropharmacology · doi:10.1016/s0028-3908(03)00167-9 · Cited by 27 · see citing works

Synthesis and structure–activity relationships of 5-substituted pyridine analogues of 3-[2-((S)-pyrrolidinyl)methoxy]pyridine, A-84543

Lin, N., Li, Y., He, Y., Holladay, M. W., Kuntzweiler, T. A., Anderson, D. J., Campbell, J. E., & Arnerić, S. P. (2001) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/s0960-894x(01)00030-0 · Cited by 23 · see citing works

Neuronal nicotinic receptors and epilepsy, from genes to possible therapeutic compounds

Hogg, R. C., & Bertrand, D. (2004) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2003.10.075 · Cited by 14 · see citing works

High Throughput Electrophysiology Using a Fully Automated, Multiplexed Recording System

Trumbull, J. D., Maslana, E. S., McKenna, D. G., et al. (2003) · Receptors and Channels · doi:10.3109/10606820308252 · Cited by 7 · see citing works

α4β2 Nicotinic Receptors with High and Low Acetylcholine Sensitivity: Pharmacology, Stoichiometry, and Sensitivity to Long-Term Exposure to Nicotine

Moroni, M., Zwart, R., Sher, E., Cassels, B. K., & Bermúdez, I. (2006) · Molecular Pharmacology · doi:10.1124/mol.106.023044 · Cited by 286 · see citing works

Ca2+ Permeability of the (α4)3(β2)2 Stoichiometry Greatly Exceeds That of (α4)2(β2)3 Human Acetylcholine Receptors

Tapia, L., Kuryatov, A., & Lindstrom, J. M. (2006) · Molecular Pharmacology · doi:10.1124/mol.106.030445 · Cited by 196 · see citing works

Roles of Accessory Subunits in α4β2* Nicotinic Receptors

Kuryatov, A., Onksen, J., & Lindstrom, J. (2008) · Molecular Pharmacology · doi:10.1124/mol.108.046789 · Cited by 195 · see citing works

Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry. Implications for drug discovery

Lester, H. A., Xiao, C., Srinivasan, R., Son, C. D., Miwa, J., Pantoja, R., Banghart, M. R., Dougherty, D. A., Goate, A. M., & Wang, J. C. (2009) · The AAPS Journal · doi:10.1208/s12248-009-9090-7 · Cited by 163 · see citing works

Sazetidine-A Is a Potent and Selective Agonist at Native and Recombinant α4β2 Nicotinic Acetylcholine Receptors

Zwart, R., Carbone, A. L., Moroni, M., Bermudez, I., Mogg, A. J., Folly, E. A., Broad, L. M., Williams, A. C., Zhang, D., Ding, C., et al. (2008) · Molecular Pharmacology · doi:10.1124/mol.108.045104 · Cited by 111 · see citing works

Augmentation of cognitive function by NS9283, a stoichiometry‐dependent positive allosteric modulator of α2‐ and α4‐containing nicotinic acetylcholine receptors

Timmermann, D. B., Sandager‐Nielsen, K., Dyhring, T., Smith, M., Jacobsen, A., Nielsen, E., Grunnet, M., Christensen, J., Peters, D., Kohlhaas, K. L., et al. (2012) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2012.01989.x · Cited by 103 · see citing works

Subcellular trafficking, pentameric assembly, and subunit stoichiometry of neuronal nicotinic acetylcholine receptors containing fluorescently labeled α6 and β3 subunits

Drenan, R. M., Nashmi, R., Imoukhuede, P., Just, H., McKinney, S., & Lester, H. A. (2008) · Molecular Pharmacology · doi:10.1124/mol.107.039180 · Cited by 100 · see citing works

Allosteric Modulators of the α7 Nicotinic Acetylcholine Receptor

Faghih, R., Gopalakrishnan, M., & Briggs, C. A. (2008) · Journal of Medicinal Chemistry · doi:10.1021/jm070256g · Cited by 86 · see citing works

Non-Agonist-Binding Subunit Interfaces Confer Distinct Functional Signatures to the Alternate Stoichiometries of the 4 2 Nicotinic Receptor: An 4- 4 Interface Is Required for Zn2+ Potentiation

Moroni, M., Vijayan, R., Carbone, A. L., Zwart, R., Biggin, P. C., & Bermúdez, I. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.1228-08.2008 · Cited by 81 · see citing works

Differential contribution of genetic variation in multiple brain nicotinic cholinergic receptors to nicotine dependence: recent progress and emerging open questions

Greenbaum, L., & Lerer, B. (2009) · Molecular Psychiatry · doi:10.1038/mp.2009.59 · Cited by 73 · see citing works

Partial Deletion of the Nicotinic Cholinergic Receptor α4 or β2 Subunit Genes Changes the Acetylcholine Sensitivity of Receptor-Mediated 86Rb+ Efflux in Cortex and Thalamus and Alters Relative Expression of α4 and β2 Subunits

Gotti, C., Moretti, M., Meinerz, N. M., Clementi, F., Gaimarri, A., Collins, A. C., & Marks, M. J. (2008) · Molecular Pharmacology · doi:10.1124/mol.108.045203 · Cited by 68 · see citing works

α6* Nicotinic Acetylcholine Receptor Expression and Function in a Visual Salience Circuit

Mackey, E. D. W., Engle, S. E., Kim, M. R., O’Neill, H. C., Wageman, C. R., Patzlaff, N. E., Wang, Y., Grady, S. R., McIntosh, J. M., Marks, M. J., et al. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.0007-12.2012 · Cited by 63 · see citing works

Role of channel activation in cognitive enhancement mediated by α7 nicotinic acetylcholine receptors

Briggs, C. A., Grønlien, J. H., Curzon, P., Timmermann, D. B., Ween, H., Thorin‐Hagene, K., Kerr, P., Anderson, D. J., Malysz, J., Dyhring, T., et al. (2009) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2009.00426.x · Cited by 62 · see citing works

Nicotine normalizes intracellular subunit stoichiometry of nicotinic receptors carrying mutations linked to autosomal dominant nocturnal frontal lobe epilepsy

Son, C. D., Moss, F. J., Cohen, B. N., & Lester, H. A. (2009) · Molecular Pharmacology · doi:10.1124/mol.108.054494 · Cited by 58 · see citing works

Nicotinic receptor-based therapeutics and candidates for smoking cessation

Dwoskin, L. P., Smith, A. M., Wooters, T. E., Zhang, Z., Crooks, P. A., & Bardo, M. T. (2009) · Biochemical Pharmacology · doi:10.1016/j.bcp.2009.06.002 · Cited by 56 · see citing works

Prenatal exposure of rats to nicotine causes persistent alterations of nicotinic cholinergic receptors

Gold, A. B., Keller, A. B., & Perry, D. C. (2008) · Brain Research · doi:10.1016/j.brainres.2008.10.076 · Cited by 55 · see citing works

Comparison of acetylcholine receptor interactions of the marine toxins, 13-desmethylspirolide C and gymnodimine

Hauser, T. A., Hepler, C. D., Kombo, D. C., Grinevich, V. P., Kiser, M. N., Hooker, D. N., Zhang, J., Mountfort, D. O., Selwood, A. I., Akireddy, S. R., et al. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.01.009 · Cited by 50 · see citing works

Stimulation of dopamine release by nicotinic acetylcholine receptor ligands in rat brain slices correlates with the profile of high, but not low, sensitivity α4β2 subunit combination

Anderson, D. J., Malysz, J., Grønlien, J. H., El Kouhen, R., Håkerud, M., Wetterstrand, C., Briggs, C. A., & Gopalakrishnan, M. (2009) · Biochemical Pharmacology · doi:10.1016/j.bcp.2009.06.024 · Cited by 44 · see citing works

Cell autonomy, receptor autonomy, and thermodynamics in nicotine receptor up-regulation

Nashmi, R., & Lester, H. (2007) · Biochemical Pharmacology · doi:10.1016/j.bcp.2007.06.040 · Cited by 43 · see citing works

A review of experimental techniques used for the heterologous expression of nicotinic acetylcholine receptors

Millar, N. S. (2009) · Biochemical Pharmacology · doi:10.1016/j.bcp.2009.06.015 · Cited by 36 · see citing works

Characterization of a Nicotine-Sensitive Neuronal Population in Rat Entorhinal Cortex

Tu, B., Gu, Z., Shen, J., Lamb, P. W., & Yakel, J. L. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.2580-09.2009 · Cited by 34 · see citing works

Differential Pharmacologies of Mecamylamine Enantiomers: Positive Allosteric Modulation and Noncompetitive Inhibition

Fedorov, N. B., Benson, L. C., Graef, J. D., Lippiello, P. M., & Bencherif, M. (2008) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.108.146910 · Cited by 34 · see citing works

Stable expression and functional characterization of a human nicotinic acetylcholine receptor with α6β2 properties: discovery of selective antagonists

Capelli, A. M., Castelletti, L., Chen, Y. H., Keyl, H. V. D., Pucci, L., Oliosi, B., Salvagno, C., Bertani, B., Gotti, C., Powell, A., et al. (2011) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2011.01213.x · Cited by 34 · see citing works

Transcriptional regulation by nicotine in dopaminergic neurons

Henley, B. M., Williams, B. A., Srinivasan, R., Cohen, B. N., Xiao, C., Mackey, E. D. W., Wold, B. J., & Lester, H. A. (2013) · Biochemical Pharmacology · doi:10.1016/j.bcp.2013.07.031 · Cited by 33 · see citing works

The high-affinity nAChR partial agonists varenicline and sazetidine-A exhibit reinforcing properties in rats

Paterson, N. E., Min, W., Hackett, A., Lowe, D., Hanania, T., Caldarone, B. J., & Ghavami, A. (2010) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.07.037 · Cited by 30 · see citing works

Selectivity of ABT-089 for α4β2* and α6β2* nicotinic acetylcholine receptors in brain

Marks, M. J., Wageman, C. R., Grady, S. R., Gopalakrishnan, M., & Briggs, C. A. (2009) · Biochemical Pharmacology · doi:10.1016/j.bcp.2009.05.022 · Cited by 30 · see citing works

Desformylflustrabromine Modulates α4β2 Neuronal Nicotinic Acetylcholine Receptor High- and Low-Sensitivity Isoforms at Allosteric Clefts Containing the β2 Subunit

Weltzin, M. M., & Schulte, M. K. (2015) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.115.223933 · Cited by 28 · see citing works

High affinity and low affinity heteromeric nicotinic acetylcholine receptors at central synapses

d’Incamps, B. L., & Ascher, P. (2014) · The Journal of Physiology · doi:10.1113/jphysiol.2014.273128 · Cited by 18 · see citing works

α3 and α7 nAChR-mediated Ca2+ transient generation in IMR-32 neuroblastoma cells

Ween, H., Thorin‐Hagene, K., Andersen, E., Grønlien, J. H., Lee, C., Gopalakrishnan, M., & Malysz, J. (2010) · Neurochemistry International · doi:10.1016/j.neuint.2010.06.005 · Cited by 15 · see citing works

Genetic matters: Thirty years of progress using mouse models in nicotinic research

Marks, M. J. (2013) · Biochemical Pharmacology · doi:10.1016/j.bcp.2013.05.021 · Cited by 13 · see citing works

Structure–Activity Studies of Diazabicyclo[3.3.0]octane-Substituted Pyrazines and Pyridines as Potent α4β2 Nicotinic Acetylcholine Receptor Ligands

Scanio, M. J. C., Shi, L., Bunnelle, W. H., Anderson, D. J., Helfrich, R. J., Malysz, J., Thorin‐Hagene, K., Handel, C. E. V., Marsh, K. C., Lee, C., et al. (2011) · Journal of Medicinal Chemistry · doi:10.1021/jm201045m · Cited by 6 · see citing works

Nicotinic Acetylcholine Receptor Subunits α4 and α5 Associated with Smoking Behaviour and Lung Cancer Are Regulated by Upstream Open Reading Frames

Reithmair, M., Aichinger, E., Pfaffl, M. W., Steinlein, O. K., & Pfob, M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0066157 · Cited by 4 · see citing works

Investigation Of The Allosteric Modulators Desformylflustrabromine And 4-(2-Hydroxyethyl)-1-Piperazineethanesulfonic Acid (Hepes) Interactions On Nicotinic Acetylcholine Receptors

Daniello-Weltzen, M. M. (2011) · ScholarWorks - UA (University of Alaska System)

BindingDB Entry 50004601: Structure-activity studies of diazabicyclo[3.3.0]octane-substituted pyrazines and pyridines as potent α4β2 nicotinic acetylcholine receptor ligands.

BindingDB (2020) · UC San Diego · doi:10.7270/q20z7646

BindingDB Entry 50038292: Allosteric modulators of the alpha7 nicotinic acetylcholine receptor.

BindingDB (2012) · UC San Diego · doi:10.7270/q2ws8v3b

Untranslated region-dependent exclusive expression of high-sensitivity subforms of α4β2 and α3β2 nicotinic acetylcholine receptors. Mol Pharmacol

Briggs, C. A., Gubbins, E. J., Marks, M. J., Putman, C. B., Thimmapaya, R., Meyer, M. D., & Surowy, C. S. (2006)

High- and Low-Sensitivity Subforms of α4β2 and α3β2 nAChRs

Briggs, C. A., Gubbins, E. J., Putman, C. B., Thimmapaya, R., Meyer, M. D., & Surowy, C. S. (2006) · Journal of Molecular Neuroscience · doi:10.1385/jmn:30:1:11 · Cited by 9 · see citing works

Stoichiometry and Pharmacology of Two Human α4β2 Nicotinic Receptor Types

Moroni, M., & Bermúdez, I. (2006) · Journal of Molecular Neuroscience · doi:10.1385/jmn:30:1:95 · Cited by 62 · see citing works

Both alpha- and beta-subunits contribute to the agonist sensitivity of neuronal nicotinic acetylcholine receptors

Luetje, C., & Patrick, J. (1991) · The Journal of Neuroscience · doi:10.1523/jneurosci.11-03-00837.1991 · Cited by 558 · see citing works

α4‐β2 and other nicotinic acetylcholine receptor subtypes as targets of psychoactive and addictive drugs

Connolly, J. G., Boulter, J., & Heinemann, S. F. (1992) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1992.tb09035.x · Cited by 69 · see citing works