An h Per2 Phosphorylation Site Mutation in Familial Advanced Sleep Phase Syndrome

A comprehensive genetic map of the human genome based on 5,264 microsatellites

Dib, C., Fauré, S., Fizames, C., Samson, D. S., Drouot, N., Alain Vignal, A., Millasseau, P., Marc, S., Kazan, J., Seboun, E., et al. (1996) · Nature · doi:10.1038/380152a0 · Cited by 2,927

Molecular Bases for Circadian Clocks

Dunlap, J. C. (1999) · Cell · doi:10.1016/s0092-8674(00)80566-8 · Cited by 2,900

Clock Mutants of Drosophila melanogaster

Konopka, R. J., & Benzer, S. (1971) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.68.9.2112 · Cited by 2,287

Interacting molecular loops in the mammalian circadian clock

Shearman, L. P., Sriram, S., Weaver, D. R., Maywood, E. S., Chaves, I., Zheng, B., Kume, K., Lee, C. C., van der, G. T. J., Horst, et al. (2000) · Science · doi:10.1126/science.288.5468.1013 · Cited by 1,367

A Differential Response of Two Putative Mammalian Circadian Regulators, mper1and mper2, to Light

Albrecht, U., Sun, Z. S., Eichele, G., & Lee, C. C. (1997) · Cell · doi:10.1016/s0092-8674(00)80495-x · Cited by 879

Three period Homologs in Mammals: Differential Light Responses in the Suprachiasmatic Circadian Clock and Oscillating Transcripts Outside of Brain

Zylka, M. J., Shearman, L. P., Weaver, D. R., & Reppert, S. M. (1998) · Neuron · doi:10.1016/s0896-6273(00)80492-4 · Cited by 865

Positional Syntenic Cloning and Functional Characterization of the Mammalian Circadian Mutation tau

Lowrey, P. L., Shimomura, K., Antoch, M. P., Yamazaki, S., Zemenides, P. D., Ralph, M. R., Menaker, M., & Takahashi, J. S. (2000) · Science · doi:10.1126/science.288.5465.483 · Cited by 860

double-time Is a Novel Drosophila Clock Gene that Regulates PERIOD Protein Accumulation

Price, J. L., Blau, J., Rothenfluh, A., Abodeely, M., Kloss, B., & Young, M. W. (1998) · Cell · doi:10.1016/s0092-8674(00)81224-6 · Cited by 839

The mPer2 gene encodes a functional component of the mammalian circadian clock

Zheng, B., Larkin, D. W., Albrecht, U., Sun, Z. S., Sage, M., Eichele, G., Lee, C. C., & Bradley, A. (1999) · Nature · doi:10.1038/22118 · Cited by 718

The Drosophila Clock Gene double-time Encodes a Protein Closely Related to Human Casein Kinase Iε

Kloss, B., Price, J. L., Sáez, L., Blau, J., Rothenfluh, A., Wesley, C. S., & Young, M. W. (1998) · Cell · doi:10.1016/s0092-8674(00)81225-8 · Cited by 682

Understanding Quantitative Circadian Regulations Are Crucial Towards Advancing Chronotherapy

Chowdhury, D., Wang, C., Lü, A., & Zhu, H. (2019) · Cells · doi:10.3390/cells8080883 · Cited by 24

Sleep phenotype of individuals with autism spectrum disorder bearing mutations in the PER2 circadian rhythm gene

Hoang, N., Yuen, R. K. C., Howe, J., Drmic, I., Ambrozewicz, P., Russell, C., Vorstman, J. A. S., Weiss, S. K., Anagnostou, E. A., Malow, B. A., et al. (2021) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.62086 · Cited by 25

Involvement of Stress Kinase Mitogen-activated Protein Kinase Kinase 7 in Regulation of Mammalian Circadian Clock

Uchida, Y., Osaki, T., Yamasaki, T., Shimomura, T., Hata, S., Horikawa, K., Shibata, S., Todo, T., Hirayama, J., & Nishina, H. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.308908 · Cited by 25

Epigenome-Wide DNA Methylation Analysis of Monozygotic Twins Discordant for Diurnal Preference

Wong, C. C. Y., Parsons, M. J., Lester, K. J., Burrage, J., Eley, T. C., Mill, J. S., Dempster, E. L., & Gregory, A. M. (2015) · Twin Research and Human Genetics · doi:10.1017/thg.2015.78 · Cited by 26

PI3K regulates BMAL1/CLOCK-mediated circadian transcription from the Dbp promoter

Morishita, Y., Miura, D., & Kida, S. (2016) · Bioscience, biotechnology and biochemistry · doi:10.1080/09168451.2015.1136885 · Cited by 22

Tired and stressed: Examining the need for sleep

Hill, V. M., O'Connor, R. M., & Shirasu‐Hiza, M. (2018) · European Journal of Neuroscience · doi:10.1111/ejn.14197 · Cited by 24

Biological clocks and the practice of psychiatry

Schulz, P. (2007) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2007.9.3/pschulz · Cited by 25

Clocks, Genes and Sleep

von Schantz, M., & Archer, S. N. (2003) · Journal of the Royal Society of Medicine · doi:10.1258/jrsm.96.10.486 · Cited by 25

Molecular Genetic Advances in Sleep Research and Their Relevance to Sleep Medicine

Wisor, J. P., & Kilduff, T. S. (2005) · SLEEP · doi:10.1093/sleep/28.3.357 · Cited by 24

Structure of an Enclosed Dimer Formed by the Drosophila Period Protein

King, H. A., Hoelz, A., Crane, B. R., & Young, M. W. (2011) · Journal of Molecular Biology · doi:10.1016/j.jmb.2011.08.048 · Cited by 24

Influence of Nocturnal Asthma on Chronotype

Ferraz, É., Borges, M. D. C., & Vianna, É. O. (2008) · Journal of Asthma · doi:10.1080/02770900802395470 · Cited by 23

New neuroscience tools that are identifying the sleep-wake circuit

Shiromani, P. J., & Peever, J. H. (2017) · SLEEP · doi:10.1093/sleep/zsx032 · Cited by 26

Streamlined procedure for gene knockouts using all-in-one adenoviral CRISPR-Cas9

Jin, Y., Joo, H., Lee, K., Kim, H., Didier, R., Yang, Y. D., Shin, H., & Lee, C. (2019) · Scientific Reports · doi:10.1038/s41598-018-36736-y · Cited by 24

Clock genes in health and diseases

Mongrain, V., & Cermakian, N. (2009) · Journal of Applied Biomedicine · doi:10.32725/jab.2009.002 · Cited by 23

Mélatonine et troubles du rythme veille-sommeil

Claustrat, B. (2009) · Médecine du Sommeil · doi:10.1016/j.msom.2009.02.001 · Cited by 24

Transcriptional feedback loops in the ovine circadian clock

Dardente, H., Fustin, J., & Hazlerigg, D. G. (2009) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/j.cbpa.2009.03.016 · Cited by 24

Circadian Rhythm Biochemistry: From Protein Degradation to Sleep and Mating

Ishida, N., Miyazaki, K., & Sakai, T. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.5207 · Cited by 24

Time-patterned drug administration: insights from a modeling approach

Goldbeter, A., & Claude, D. (2002) · Chronobiology International · doi:10.1081/cbi-120002596 · Cited by 24

Phosphorylation of DNA-binding domains of CLOCK–BMAL1 complex for PER-dependent inhibition in circadian clock of mammalian cells

Otobe, Y., Jeong, E. M., Ito, S., Shinohara, Y., Kurabayashi, N., Aiba, A., Fukada, Y., Kim, J. K., & Yoshitane, H. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2316858121 · Cited by 23

Circadian rhythm disturbances in Alzheimer’s disease: insights from plaque-free and plaque-burdened stages in APPSWE/PS1dE9 mice

Yang, H., Niu, L., Tian, L., Hu, Y., Cheng, C., Li, S., & Le, W. (2025) · Alzheimer s Research & Therapy · doi:10.1186/s13195-025-01724-8 · Cited by 23

Control of circadian rhythm on cortical excitability and synaptic plasticity

Lodovichi, C., & Ratto, G. M. (2023) · Frontiers in Neural Circuits · doi:10.3389/fncir.2023.1099598 · Cited by 23

Identification of circadian gene variants in bipolar disorder in Latino populations

Gonzalez, R., Gonzalez, S., Villa, E. C., Ramírez, M., Zavala, J., Armas, R., Contreras, J., Dassori, A. M., Leach, R. J., Flores, D. L., et al. (2015) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.07.014 · Cited by 23

From molecules to behavior and the clinic: Integration in chronobiology

Bechtel, W. (2012) · Studies in History and Philosophy of Science Part C Studies in History and Philosophy of Biological and Biomedical Sciences · doi:10.1016/j.shpsc.2012.10.001 · Cited by 23

A role for casein kinase 2a in the Drosophila circadian clock

Lin, J.-M., Kilman, V. L., Keegan, K. P., Paddock, B. E., Emery-Le, M., Rosbash, M., & Allada, R. (2002) · Cited by 23

An Overview of Normal Sleep

Chokroverty, S. (2009) · Elsevier eBooks · doi:10.1016/b978-0-7506-7584-0.00002-1 · Cited by 23

A cross-sectional study on the relationships among the polymorphism of period2 gene, work stress, and insomnia

Ju, L., Huang, C., Lan, Y., & Wang, Y. (2015) · Sleep And Breathing · doi:10.1007/s11325-015-1229-4 · Cited by 23

Genetic Basis for Sleep Regulation and Sleep Disorders

Raizen, D. M., Mason, T. A., & Pack, A. I. (2006) · Seminars in Neurology · doi:10.1055/s-2006-951619 · Cited by 22

Biochemical characterization of the recombinant human Drosophila homologues Timekeeper and Andante involved in the Drosophila circadian oscillator

Rasmussen, T., Skjøth, I. H. E., Jensen, H. H., Niefind, K., Boldyreff, B., & Issinger, O. (2005) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-005-2944-0 · Cited by 23

Dexras1: Shaping the responsiveness of the circadian clock

Cheng, H. M., & Obrietan, K. H. (2006) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2006.03.006 · Cited by 23

Toward a Molecular Biological Calendar?

Hastings, M. H., & Follett, B. K. (2001) · Journal of Biological Rhythms · doi:10.1177/074873001129002015 · Cited by 23

The hidden rhythms of epilepsy: exploring biological clocks and epileptic seizure dynamics

Niu, R., Guo, X., Wang, J., & Yang, X. (2025) · Acta Epileptologica · doi:10.1186/s42494-024-00197-w · Cited by 22

Clinical Chronobiology: Circadian Rhythms in Health and Disease

Tomatsu, S., Abbott, S. M., & Attarian, H. P. (2025) · Seminars in Neurology · doi:10.1055/a-2538-3259 · Cited by 27

Application of an ex vivo cellular model of circadian variation for bipolar disorder research: a proof of concept study

Bamne, M. N., Ponder, C. A., Wood, J. A., Mansour, H., Frank, E., Kupfer, D. J., Young, M. W., & Nimgaonkar, V. L. (2013) · Bipolar Disorders · doi:10.1111/bdi.12095 · Cited by 22

The genomic landscape of human cellular circadian variation points to a novel role for the signalosome

Gaspar, L., Howald, C., Popadin, K. Y., Maier, B., Mauvoisin, D., Moriggi, E., Gutiérrez‐Arcelus, M., Falconnet, E., Borel, C., Kunz, D., et al. (2017) · eLife · doi:10.7554/elife.24994 · Cited by 22

Phosphatase of Regenerating Liver-1 Selectively Times Circadian Behavior in Darkness via Function in PDF Neurons and Dephosphorylation of TIMELESS

Kula-Eversole, E., Lee, D. H., Samba, I., Yildirim, E., Levine, D. C., Hong, H., Lear, B. C., Bass, J. T., Rosbash, M., & Allada, R. (2020) · Current Biology · doi:10.1016/j.cub.2020.10.013 · Cited by 22

Familial natural short sleep mutations reduce Alzheimer pathology in mice

Dong, Q., Gentry, N. W., McMahon, T., Yamazaki, M., Benitez-Rivera, L., Wang, T., Gan, L., Ptáček, L. J., & Fu, Y. (2022) · iScience · doi:10.1016/j.isci.2022.103964 · Cited by 22

The history of sleep research and sleep medicine in Europe

Schulz, H. (2022) · Journal of Sleep Research · doi:10.1111/jsr.13602 · Cited by 22

Mammalian circadian clock proteins form dynamic interacting microbodies distinct from phase separation

Xie, P., Xie, X., Ye, C., Dean, K. M., Laothamatas, I., Taufique, S. K. T., Takahashi, J. S., Yamazaki, S., Xu, Y., & Liu, Y. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2318274120 · Cited by 22

Impacts of aging on circadian rhythm and related sleep disorders

Li, Y., Tan, Y., & Zhao, Z. (2023) · Biosystems · doi:10.1016/j.biosystems.2023.105111 · Cited by 24

The Impact of Melatonin in Research

Varoni, E. M., Soru, C., Pluchino, R., Intra, C., & Iriti, M. (2016) · Molecules · doi:10.3390/molecules21020240 · Cited by 21

Molecular neurobiology of sleep

Cirelli, C., & Tononi, G. (2010) · Handbook of clinical neurology · doi:10.1016/b978-0-444-52006-7.00012-5 · Cited by 22

Expression analysis of circadian genes in oocytes and preimplantation embryos of cattle and rabbits

Amano, T., Tokunaga, K., Kakegawa, R., 柳澤, 文., Takemoto, A., Tatemizo, A., Watanabe, T., Hatanaka, Y., Matsushita, A., Kishi, M., et al. (2010) · Animal Reproduction Science · doi:10.1016/j.anireprosci.2010.05.020 · Cited by 22

Analysis of Cell Type-specific Expression of CK1ε in Various Tissues of Young Adult BALB/c Mice and in Mammary Tumors of SV40 T-Ag-transgenic Mice

Utz, A. C., Hirner, H., Blatz, A., Hillenbrand, A., Schmidt, B., Deppert, W., Henne‐Bruns, D., Fischer, D., Thal, D. R., Leithäuser, F., et al. (2009) · Journal of Histochemistry & Cytochemistry · doi:10.1369/jhc.2009.954628 · Cited by 22

Phosphorylation of human calsequestrin: implications for calcium regulation

Sanchez, E. J., Munske, G. R., Criswell, A. R., Milting, H., Dunker, A. K., & Kang, C. (2011) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-011-0787-4 · Cited by 22

Beyond Intuitive Modeling: Combining Biophysical Models with Innovative Experiments to Move the Circadian Clock Field Forward

Forger, D. B., Gonze, D., Virshup, D. M., & Welsh, D. K. (2007) · Journal of Biological Rhythms · doi:10.1177/0748730407301823 · Cited by 22

Functional Genomics of Sleep and Circadian Rhythm Invited Review: Regulation of mammalian circadian clock genes

Albrecht, U. (2002) · Cited by 22

Circadian Disorders of the Sleep-Wake Cycle

Reid, K. J., & Zee, P. C. (2005) · Elsevier eBooks · doi:10.1016/b0-72-160797-7/50065-3 · Cited by 21

Sleep and Biological Rhythms

Jones, S. G., & Benca, R. M. (2012) · Wiley eBooks · doi:10.1002/9781118133880.hop203013 · Cited by 23

Structure Function Analysis of Mammalian CryptochromesPreprint

Tamanini, F., Chaves, I., Bajek, M. I., & van der Horst, G. T. J. (2007) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2007.72.066 · Cited by 23

Big Ben Rings in a Lesson on Biological Clocks

Young, M. W. (2002) · Neuron · doi:10.1016/s0896-6273(02)01127-3 · Cited by 22

High-throughput discovery of genetic determinants of circadian misalignment

Zhang, T., Xie, P., Dong, Y., Liu, Z., Zhou, F., Pan, D., Huang, Z., Zhai, Q., Gu, Y., Wu, Q., et al. (2020) · PLoS Genetics · doi:10.1371/journal.pgen.1008577 · Cited by 21

PER2 Differentially Regulates Clock Phosphorylation versus Transcription by Reciprocal Switching of CK1ε Activity

Qin, X., Mori, T., Zhang, Y., & Johnson, C. H. (2015) · Journal of Biological Rhythms · doi:10.1177/0748730415582127 · Cited by 21

Altered Phase-Relationship between Peripheral Oscillators and Environmental Time in Cry1 or Cry2 Deficient Mouse Models for Early and Late Chronotypes

Destici, E., Jacobs, E. H., Tamanini, F., Loos, M., van der Horst, G. T. J., & Oklejewicz, M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0083602 · Cited by 22

Genetic Variability of Arylalkylamine-N-Acetyl-Transferase (AA-NAT) Gene and Human Sleep/Wake Pattern

Wang, G. Y., Lee, C. G. L., & Lee, E. J. D. (2004) · Chronobiology International · doi:10.1081/cbi-120037822 · Cited by 21

Narcolepsy and familial advanced sleep-phase syndrome: molecular genetics of sleep disorders

Tafti, M., Dauvilliers, Y. A., & Overeem, S. (2007) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2007.04.007 · Cited by 21

Of switches and hourglasses: regulation of subcellular traffic in circadian clocks by phosphorylation

Tataroğlu, Ö., & Schafmeier, T. (2010) · EMBO Reports · doi:10.1038/embor.2010.174 · Cited by 22

A missense variant in PER2 is associated with delayed sleep–wake phase disorder in a Japanese population

Miyagawa, T., Hida, A., Shimada, M., Uehara, C., Nishino, Y., Kadotani, H., Uchiyama, M., Ebisawa, T., Inoue, Y., Kamei, Y., et al. (2019) · Journal of Human Genetics · doi:10.1038/s10038-019-0665-6 · Cited by 21

Owls and Larks in Mice

Pfeffer, M., Wicht, H., von Gall, C., & Korf, H. (2015) · Frontiers in Neurology · doi:10.3389/fneur.2015.00101 · Cited by 22

Immunohistochemical Characterisation of Cell-Type Specific Expression of CK1δ in Various Tissues of Young Adult BALB/c Mice

Löhler, J., Hirner, H., Schmidt, B., Kramer, K. M., Fischer, D., Thal, D. R., Leithäuser, F., & Knippschild, U. (2009) · PLoS ONE · doi:10.1371/journal.pone.0004174 · Cited by 21

Per2-Mediated Vascular Dysfunction Is Caused by the Upregulation of the Connective Tissue Growth Factor (CTGF)

Jadhav, V., Luo, Q., Dominguez, J. M., Al-Sabah, J., Chaqour, B., Grant, M. B., & Bhatwadekar, A. D. (2016) · PLoS ONE · doi:10.1371/journal.pone.0163367 · Cited by 21

Association of the 54‐nucleotide repeat polymorphism of hPer3 with heroin dependence in Han Chinese population

Ya, Z., Liao, G., Liu, Y., Wang, Y., Yang, Z., Lin, Y., Shen, Y., Li, S., Xiao, J., Guo, H., et al. (2007) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2007.00314.x · Cited by 21

N-ethyl-N-nitrosourea mouse mutants in the dissection of behavioural and psychiatric disorders

Keays, D. A., & Nolan, P. M. (2003) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2003.08.107 · Cited by 21

Signaling components that drive circadian rhythms

Wang, G. K. (2002) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(02)00324-0 · Cited by 21

Posttranslational Control of theNeurospora CircadianClockPreprint

Cha, J., Huang, G. N., Guo, J., & Liu, Y. (2007) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2007.72.010 · Cited by 21

Biochemical mechanism of the mammalian circadian clock

Liu, Y., & Sancar, A. (2025) · FEBS Letters · doi:10.1002/1873-3468.70150 · Cited by 33

Genetic Correlates of Individual Differences in Sleep Behavior of Free-Living Great Tits (Parus major)

Stuber, E. F., Baumgartner, C., Dingemanse, N. J., Kempenaers, B., & Mueller, J. C. (2016) · G3 Genes Genomes Genetics · doi:10.1534/g3.115.024216 · Cited by 21

Chrono-Drug Discovery and Development Based on Circadian Rhythm of Molecular, Cellular and Organ Level

Ohdo, S. (2021) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b21-00277 · Cited by 20

Evolutionary conservations, changes of circadian rhythms and their effect on circadian disturbances and therapeutic approaches

Palm, D., Uzoni, A., Simon, F., Fischer, M., Coogan, A., Tucha, O., Thome, J., & Faltraco, F. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.06.007 · Cited by 20

Differential effects of SUMO1 and SUMO2 on circadian protein PER2 stability and function

Chen, L.-C., Hsieh, Y.-L., Tan, G. Y. T., Kuo, T.-Y., Chou, Y., Hsu, P., & Hwang‐Verslues, W. W. (2021) · Scientific Reports · doi:10.1038/s41598-021-93933-y · Cited by 22

Sleep need, the key regulator of sleep homeostasis, is indicated and controlled by phosphorylation of threonine 221 in salt-inducible kinase 3

Li, Y., Li, C., Liu, Y., Yu, J., Yang, J., Cui, Y., Wang, T. V., Li, C., Jiang, L., Song, M., et al. (2023) · Genetics · doi:10.1093/genetics/iyad136 · Cited by 20

Chronobiology in mammalian health

Liu, Z., & Chu, G. (2012) · Molecular Biology Reports · doi:10.1007/s11033-012-2330-4 · Cited by 20

Circadian Dysrhythmias, Physiological Aberrations, and the Link to Skin Cancer

Gutiérrez, D., & Arbesman, J. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17050621 · Cited by 21

PhosphoPICK-SNP: quantifying the effect of amino acid variants on protein phosphorylation

Patrick, R., Kobe, B., Cao, K. L., & Mikael Bodén, A. (2017) · Bioinformatics · doi:10.1093/bioinformatics/btx072 · Cited by 20

Testing for associations between candidate genes for circadian rhythms and individual variation in sleep behaviour in blue tits

Steinmeyer, C., Kempenaers, B., & Mueller, J. C. (2012) · Genetica · doi:10.1007/s10709-012-9673-6 · Cited by 21

Deregulation of the circadian clock constitutes a significant factor in tumorigenesis: a clockwork cancer. Part II.In vivostudies

Uth, K., & Sleigh, R. (2014) · Biotechnology & Biotechnological Equipment · doi:10.1080/13102818.2014.925298 · Cited by 20

Systems Biology of Circadian Rhythms: An Outlook

Haro, L. D., & Panda, S. (2006) · Journal of Biological Rhythms · doi:10.1177/0748730406294767 · Cited by 20

Molecular signals of Mammalian circadian clock.

Zhang, J., Dong, X., Fujimoto, Y., & Okamura, H. (2004) · PubMed · doi:10.24546/00422044 · Cited by 20

BMAL1 dephosphorylation determines the pace of the circadian clockPreprint

Schibler, U. (2021) · Genes & Development · doi:10.1101/gad.348801.121 · Cited by 20

The Genetics of the Human Circadian Clock

Zhang, L., Jones, C. R., Ptáček, L. J., & Fu, Y. (2011) · Advances in genetics · doi:10.1016/b978-0-12-387690-4.00007-6 · Cited by 21

Identification of novel small molecules targeting core clock proteins to regulate circadian rhythm

Kavaklı, İ. H., Gül, Ş., & Türkay, M. (2021) · Current Opinion in Chemical Engineering · doi:10.1016/j.coche.2021.100730 · Cited by 18

Chronopharmacology of immune-related diseases

Ohdo, S., Koyanagi, S., & Matsunaga, N. (2022) · Allergology International · doi:10.1016/j.alit.2022.06.006 · Cited by 19

Molecular Mechanism of the Circadian Clock

Doležel, D. (2023) · Entomology monographs · doi:10.1007/978-981-99-0726-7_4 · Cited by 18

Altered expression profiles of clock genes hPer1 and hPer2 in peripheral blood mononuclear cells of cancer patients undergoing surgery

Azama, T., Yano, M., Oishi, K., Kadota, K., Hyun, K., Tokura, H., Nishimura, S., Matsunaga, T., Iwanaga, H., Miki, H., et al. (2006) · Life Sciences · doi:10.1016/j.lfs.2006.11.048 · Cited by 19

Circadian Metabolic Regulation through Crosstalk between Casein Kinase 1δ and Transcriptional Coactivator PGC-1α

Li, S., Chen, X., Yu, L., Saltiel, A. R., & Lin, J. D. (2011) · Molecular Endocrinology · doi:10.1210/me.2011-1227 · Cited by 19

Decomposition Analyses Applied to a Complex Ultradian Biorhythm: The Oscillating NADH Oxidase Activity of Plasma Membranes Having a Potential Time-Keeping (Clock) Function

Foster, K. A., Anwar, N., Pogue, R., Morré, D. M., Keenan, T. W., & Morré, D. J. (2003) · Nonlinearity in Biology Toxicology Medicine · doi:10.1080/15401420390844465 · Cited by 19

Physiology of the Mammalian Circadian System

Rosenwasser, A. M., & Turek, F. W. (2011) · Elsevier eBooks · doi:10.1016/b978-1-4160-6645-3.00034-7 · Cited by 20

Precision Medicine in Circadian Rhythm Sleep–Wake Disorders: Current State and Future Perspectives

Keijzer, H., Snitselaar, M. A., Smits, M. G., Spruyt, K., Zee, P. C., Ehrhart, F., & Curfs, L. (2017) · Personalized Medicine · doi:10.2217/pme-2016-0079 · Cited by 19

Metabolic dysfunction and circadian rhythm abnormalities in adolescents with sleep disturbance

Tomoda, A., Kawatani, J., Joudoi, T., Hamada, A., & Miike, T. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.02.038 · Cited by 19

Mind, Brain, Education, and Biological Timing

Golombek, D. A., & Cardinali, D. P. (2008) · Mind Brain and Education · doi:10.1111/j.1751-228x.2008.00022.x · Cited by 19

The reduced kinome of Ostreococcus tauri: core eukaryotic signalling components in a tractable model species

Hindle, M., Martin, S. F., Noordally, Z. B., Gerben Van Ooijen, A., Barrios-Llerena, M. E., Simpson, T. I., Bihan, T. L., & Millar, A. J. (2014) · BMC Genomics · doi:10.1186/1471-2164-15-640 · Cited by 19

A novel SNP inhPer2associates with diurnal preference in a healthy population

Matsuo, M., Shiino, Y., Yamada, N., Ozeki, Y., & Okawa, M. (2007) · Sleep and Biological Rhythms · doi:10.1111/j.1479-8425.2007.00264.x · Cited by 19

Circadian Rhythm Sleep Disorders in Children and Adolescents

Wyatt, J. K. (2007) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2007.05.017 · Cited by 19

Structural Features Underlying the Multisite Phosphorylation of the A Domain of the NF-AT4 Transcription Factor by Protein Kinase CK1

Marin, O., Burzio, V. A., Boschetti, M., Meggio, F., Allende, C. C., Allende, J. E., & Pinna, L. A. (2001) · Biochemistry · doi:10.1021/bi0112309 · Cited by 19

GWAS in 446,118 European adults identifies 78 genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates

Dashti, H. S., Jones, S. E., Wood, A. R., Lane, J. M., van Hees, V. T., Wang, H., Rhodes, J. A., Song, Y., Patel, K., Anderson, S. G., et al. (2018) · doi:10.1101/274977 · Cited by 614

Protein Kinases in the Photic Signaling of the Mammalian Circadian Clock.

Alessandro, M. S., Golombek, D. A., & Chiesa, J. J. (2019) · PubMed Central · Cited by 18

PRD-2 directly regulates casein kinase I and counteracts nonsense-mediated decay in the Neurospora circadian clock

Kelliher, C., Lambreghts, R., Xiang, Q., Baker, C. L., Loros, J., & Dunlap, J. (2020) · eLife · doi:10.7554/elife.64007 · Cited by 18

Genetic Mechanisms of Migraine: Insights from Monogenic Migraine Mutations

Gosalia, H., Karsan, N., & Goadsby, P. J. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241612697 · Cited by 18

PAS Dimerization at the Nexus of the Mammalian Circadian Clock

Sharma, D., & Partch, C. L. (2023) · Journal of Molecular Biology · doi:10.1016/j.jmb.2023.168341 · Cited by 20

Readjustment of circadian clocks by exercise intervention is a potential therapeutic target for sleep disorders: a narrative review

Lee, K., Hong, K., Park, J., & Park, W. (2024) · Physical Activity and Nutrition · doi:10.20463/pan.2024.0014 · Cited by 20

Circadian Rhythm Sleep Disorders

Barion, A. (2011) · Disease-a-Month · doi:10.1016/j.disamonth.2011.06.003 · Cited by 19

An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome. Science 291:1040–1043

Toh, K. L., Jones, C. R., He, Y., Eide, E. J., Hinz, W. A., Virshup, D. M., Ptáček, L. J., & Fu, Y. (2001)

Touching base

(2001) · Nature Genetics · doi:10.1038/84746

Functional consequences of a CKIδ mutation causing familial advanced sleep phase syndrome

Xu, Y., Padiath, Q. S., Shapiro, R. E., Jones, C. R., Wu, S. C., Saigoh, N., Saigoh, K., Ptáček, L. J., & Fu, Y.-H. (2005) · Nature · doi:10.1038/nature03453 · Cited by 861

First human ‘clock’ gene

Dell, H. (2001) · Trends in Genetics · doi:10.1016/s0168-9525(01)02253-3

A Family of Larks

(2001) · Science s STKE · doi:10.1126/stke.2001.69.tw7