The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Scanning Probe Evolution in Biology
Abstract
Twenty years ago the first scanning probe instrument, the scanning tunneling microscope, opened up new realms for our perception of the world. Atoms that had been abstract entities were now real objects, clearly seen as distinguishable individuals at particular positions in space. A whole family of scanning probe instruments has been developed, extending our sense of touching to the scale of atoms and molecules. Such instruments are especially useful for imaging of biomolecular structures because they can produce topographic images with submolecular resolution in aqueous environments. Instruments with increased imaging rates, lower probe-specimen force interactions, and probe configurations not constrained to planar surfaces are being developed, with the goal of imaging processes at the single-molecule level—not only at surfaces but also within three-dimensional volumes—in real time.
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Cites
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Self-citationHigh-Q Dynamic Force Microscopy in Liquid and Its Application to Living Cells
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Cited by
Jeyaraj, M., Gurunathan, S., Qasim, M., Kang, M.-H., & Kim, J.-H. (2019) · Nanomaterials · doi:10.3390/nano9121719 · Cited by 481
Probing Liquid/Solid Interfaces at the Molecular Level
Zaera, F. (2012) · Chemical Reviews · doi:10.1021/cr2002068 · Cited by 458
Single-molecule experiments in biological physics: methods and applications
Ritort, F. (2006) · Journal of Physics: Condensed Matter · doi:10.1088/0953-8984/18/32/r01 · Cited by 393
A review of imaging techniques for systems biology
Kherlopian, A. R., Song, T., Duan, Q., Neimark, M. A., Po, M. J., Gohagan, J. K., & Laine, A. F. (2008) · BMC Systems Biology · doi:10.1186/1752-0509-2-74 · Cited by 310
Surface strategies for control of neuronal cell adhesion: A review
Roach, P., Parker, T., Gadegaard, N., & Alexander, M. R. (2010) · Surface Science Reports · doi:10.1016/j.surfrep.2010.07.001 · Cited by 180
Metadata
- Authors
- Hörber, J. K. H., & Miles, M. J.
- Venue
- Science
- Published
- 2003-11-07
- Volume
- 302
- Issue
- 5647
- Pages
- 1002-1005
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2160165626
- Cited by
- 353
- References
- 12
- FWCI
- 15.18
- Type
- journal article
- Language
- en
- Open access
- closed
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