The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
Composition and Formation of Intercellular Junctions in Epithelial Cells
Abstract
The polarized nature of epithelial cells is manifested by the nonrandom partitioning of organelles within the cells, the concentration of intercellular junctions at one pole, and the asymmetric distribution of proteins and lipids within the plasma membrane. These features allow epithelia to fulfill their specific tasks, such as targeted uptake and secretion of molecules and the segregation of different tissue compartments. The accessibility of Drosophila melanogaster and Caenorhabditis elegans to genetic and cell biological analyses, combined with the study of mammalian cells in culture, provides an ideal basis for understanding the mechanisms that control the establishment and maintenance of epithelial cell polarity and tissue integrity. Here, we focus on some of the best-studied junctions and membrane-associated protein complexes and their relation to cell polarity. Comparisons between fly, worm, and vertebrate epithelia reveal marked similarities with respect to the molecules used, and pronounced differences in the organization of the junctions themselves.
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Cites
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Cited by
Myosin-dependent junction remodelling controls planar cell intercalation and axis elongation
Bertet, C., Sulak, L., & Lecuit, T. (2004) · Nature · doi:10.1038/nature02590 · Cited by 1,020
Perez-Moreno, M., Jamora, C., & Fuchs, E. (2003) · Cell · doi:10.1016/s0092-8674(03)00108-9 · Cited by 721
Adaptation of core mechanisms to generate cell polarity
Nelson, W. J. (2003) · Nature · doi:10.1038/nature01602 · Cited by 716
Harris, T. J. C., & Peifer, M. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200505127 · Cited by 295
Tricellulin is a tight-junction protein necessary for hearing
Riazuddin, S., Ahmed, Z. M., Fanning, A. S., Lagziel, A., Kitajiri, S.-I., Ramzan, K., Khan, S. N., Chattaraj, P., Friedman, P. L., Anderson, J. M., et al. (2006) · The American Journal of Human Genetics · doi:10.1086/510022 · Cited by 283
Metadata
- Authors
- Knust, E., & Bossinger, O.
- Venue
- Science
- Published
- 2002-12-06
- Volume
- 298
- Issue
- 5600
- Pages
- 1955-1959
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2163043134
- Cited by
- 423
- References
- 47
- FWCI
- 15.18
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
