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mRNA display selection of a high‐affinity, Bcl‐X L ‐specific binding peptide

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Identification and Evaluation of the Minimum Unit of a KALA Peptide Required for Gene Delivery and Immune Activation

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A Peptide Backbone Stapling Strategy Enabled by the Multicomponent Incorporation of Amide N‐Substituents

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Assessing Interactions between Helical Aromatic Oligoamide Foldamers and Protein Surfaces: A Tethering Approach

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Precisely Regulated and Efficient Locking of Linear Peptides into Stable Multicyclic Topologies through a One‐Pot Reaction

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Recognition Dynamics of p53 and MDM2: Implications for Peptide Design

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Challenges in Targeting a Basic Helix–Loop–Helix Transcription Factor with Hydrocarbon-Stapled Peptides

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The Stapled AKAP Disruptor Peptide STAD-2 Displays Antimalarial Activity through a PKA-Independent Mechanism

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pH-Responsive Peptide Nanoparticles Deliver Macromolecules to Cells via Endosomal Membrane Nanoporation

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Baxter, D., Ullman, C. G., & Mason, J. M. (2014) · Future Medicinal Chemistry · doi:10.4155/fmc.14.134 · Cited by 14

Computer applications for prediction of protein–protein interactions and rational drug design

Fernández‐Recio, J. (2009) · Advances and Applications in Bioinformatics and Chemistry · doi:10.2147/aabc.s6272 · Cited by 14

Helix Nucleation by the Smallest Known α‐Helix in Water

Hoang, H. N., Driver, R. W., Beyer, R. L., Hill, T. A., de Araujo, A. D., Plisson, F., Harrison, R. S., Goedecke, L., Shepherd, N. E., & Fairlie, D. P. (2016) · Angewandte Chemie · doi:10.1002/ange.201602079 · Cited by 14

Exploration of Structure−Activity Relationships among Foldamer Ligands for a Specific Protein Binding Site via Parallel and Split-and-Mix Library Synthesis

Murray, J. K., Sadowsky, J., Scalf, M., Smith, L. M., Tomita, Y. A., & Gellman, S. H. (2008) · Journal of Combinatorial Chemistry · doi:10.1021/cc700153z · Cited by 14

Late-Stage Aromatic C–H Bond Functionalization for Cysteine/Selenocysteine Bioconjugation

Zhao, Z., Huang, J. Q., Cai, Y., Zhou, T., Khatib, F., Shimon, D., Wang, B., & Metanis, N. (2025) · Journal of the American Chemical Society · doi:10.1021/jacs.5c08936 · Cited by 13

Direkte Modulation von Rab‐GTPase‐Effektor‐Wechselwirkungen

Spiegel, J., Cromm, P. M., Itzen, A., Goody, R. S., Grossmann, T. N., & Waldmann, H. (2014) · Angewandte Chemie · doi:10.1002/ange.201308568 · Cited by 13

Design, Synthesis, and Biological Evaluation of Lysine-Stapled Peptide Inhibitors of p53-MDM2/MDMX Interactions with Potent Antitumor Activity In Vivo

Xu, L., Fan, X., He, Y., Xia, X., & Zhang, J. (2024) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.4c01939 · Cited by 14

Peptides as Targeting Agents and Therapeutics: A Brief Overview

Warthen, J. L., & Lueckheide, M. J. (2024) · Biomacromolecules · doi:10.1021/acs.biomac.4c00518 · Cited by 13

The use of a neutral peptide aptamer scaffold to anchor BH3 peptides constitutes a viable approach to studying their function

Stadler, L. K. J., Tomlinson, D. C., Lee, T., Knowles, M. A., & Ferrigno, P. K. (2014) · Cell Death and Disease · doi:10.1038/cddis.2013.564 · Cited by 13

Positioning and Configuration of Key Atoms Influence the Topology of [13]-Macrodiolides

Ma, J., & Peczuh, M. W. (2013) · The Journal of Organic Chemistry · doi:10.1021/jo400383g · Cited by 13

HDL Mimetic Peptide ATI-5261 Forms an Oligomeric Assembly in Solution That Dissociates to Monomers upon Dilution

Zheng, Y. Y., Patel, A., Narayanaswami, V., Hura, G. L., Hang, B., & Bielicki, J. K. (2011) · Biochemistry · doi:10.1021/bi2002955 · Cited by 14

Advancements in Stapled Peptide Drug Discovery & Development

Guerlavais, V., & Sawyer, T. K. (2014) · Annual reports in medicinal chemistry · doi:10.1016/b978-0-12-800167-7.00021-3 · Cited by 13

Targeted β‐catenin ubiquitination and degradation by multifunctional stapled peptides

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Cooperative Stapling of Native Peptides at Lysine and Tyrosine or Arginine with Formaldehyde

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Evolving therapeutic proteins to precisely kill cancer cells

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Rapid Evaluation of Staple Placement in Stabilized α Helices Using Bacterial Surface Display

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Inhibition of caspase‐9 by stabilized peptides targeting the dimerization interface

Huber, K. L., Ghosh, S., & Hardy, J. A. (2012) · Biopolymers · doi:10.1002/bip.22080 · Cited by 14

Protein stapling via azide–alkyne ligation

Abdeljabbar, D. M., Piscotta, F. J., Zhang, S., & Link, A. J. (2014) · Chemical Communications · doi:10.1039/c4cc06528j · Cited by 13

Tunable helicity, stability and DNA-binding properties of short peptides with hybrid metal coordination motifs

Smith, S. J., Radford, R. J., Subramanian, R. H., Barnett, B. R., Figueroa, J. S., & Tezcan, F. A. (2016) · Chemical Science · doi:10.1039/c6sc00826g · Cited by 13

Rational design and screening of peptide-based inhibitors of heat shock factor 1 (HSF1)

Xu, R., Burchfiel, E. T., Dong, B., Rettko, N. J., Dunyak, B. M., Shao, H., Thiele, D. J., & Gestwicki, J. E. (2018) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2018.04.018 · Cited by 13

Anti-Leukemic Potency of Stapled BH3 Helices Correlates with Their Capacity for Bifunctional Activation of Apoptotic Pathways.

Walensky, L. D., Pitter, K. L., Morash, J. G., Verdine, G. L., & Korsmeyer, S. J. (2006) · Blood · doi:10.1182/blood.v108.11.711.711

Abstract SY37-01: Dissecting the canonical and noncanonical interactions of the BCL-2 family for therapeutic benefit

Walensky, L. D. (2014) · Cancer Research · doi:10.1158/1538-7445.am2014-sy37-01

Dissecting the BCL‐2 family interaction network with stapled peptides: mechanistic insights and pharmacologic opportunities

Walensky, L. D. (2012) · The FASEB Journal · doi:10.1096/fasebj.26.1_supplement.220.1

Abstract 4611: Multimodal activation of apoptosis by a hydrocarbon-stapled PUMA BH3 helix.

Edwards, A., Gavathiotis, E., LaBelle, J. L., Braun, C. R., Opoku-Nsiah, K., Bird, G. H., & Walensky, L. D. (2013) · Cancer Research · doi:10.1158/1538-7445.am2013-4611 · Cited by 1

Chapter 22 Synthesis and Biophysical Characterization of Stabilized α‐Helices of BCL‐2 Domains

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