Cited by 2,607Cellular Mechanics and InteractionsTissue Engineering and Regenerative MedicineBone Tissue Engineering Materials

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Exploring and Engineering the Cell Surface Interface

Stevens, Molly M., George, Julian H.·2005·Science

DOI 10.1126/science.1106587

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Abstract

Cells are inherently sensitive to local mesoscale, microscale, and nanoscale patterns of chemistry and topography. We review current approaches to control cell behavior through the nanoscale engineering of materials surfaces. Far-reaching implications are emerging for applications including medical implants, cell supports, and materials that can be used as instructive three-dimensional environments for tissue regeneration.

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Lutolf, M. P., & Hubbell, J. A. (2005) · Nature Biotechnology · doi:10.1038/nbt1055 · Cited by 4,551
Integrin signaling
Giancotti, F. G., & Ruoslahti, E. (1999) · Science · doi:10.1126/science.285.5430.1028 · Cited by 3,869
Self-Assembly and Mineralization of Peptide-Amphiphile Nanofibers
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Fabrication of novel biomaterials through molecular self-assembly
Zhang, S. (2003) · Nature Biotechnology · doi:10.1038/nbt874 · Cited by 3,375
Taking Cell-Matrix Adhesions to the Third Dimension
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Third-Generation Biomedical Materials
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D. Gullberg, P. Ekblom, Int. J. Dev. Biol.39, 845 (1995).
J. E. Scott, J. Anat.187, 259 (1995).
E. I. Wallner, Q. Yang, D. R. Peterson, J. Wada, Y. S. Kanwar, Am. J. Physiol.275, F467 (1998).
A. Curtis, C. Wilkinson, Biochem. Soc. Symp.65, 15 (1999).
K. M. Woo, V. J. Chen, P. X. Ma, J. Biomed. Mater. Res. A67, 531 (2003).
J. C. van Hest, D. A. Tirrell, Chem. Commun. (Camb.)1897 (2001).

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Wilson, J. T., Cui, W., Kozlovskaya, V., Kharlampieva, E., Pan, D., Qu, Z., Krishnamurthy, V. R., Mets, J. M., Kumar, V., Wen, J., et al. (2011) · Journal of the American Chemical Society · doi:10.1021/ja110926s · Cited by 206
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Authors: Stevens, M. M., & George, J. H.
Affiliations: Imperial College London (GB)
Corresponding author: Stevens, Molly M.
ORCID: Stevens, Molly M.
George, Julian H.
Venue: Science
Publisher: American Association for the Advancement of Science (AAAS)
Published: 2005-11-18
Volume: 310
Issue: 5751
Pages: 1135-1138
ISSN: 0036-8075 (ISSN-L)
1095-9203
DOI: 10.1126/science.1106587
OpenAlex: W1982769493
Cited by: 2,607
References: 64
Citations by year: 2026: 30 · 2025: 57 · 2024: 57 · 2023: 90 · 2022: 91 · 2021: 117 · 2020: 132 · 2019: 126 · 2018: 165 · 2017: 166 · 2016: 185 · 2015: 145 · 2014: 202 · 2013: 177 · 2012: 177
FWCI: 5.32
Type: journal article
Language: en
Open access: closed
Locations: Science (publishedVersion)
PubMed (publishedVersion)
Funders: Engineering and Physical Sciences Research Council (EP/C520742/1)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular Mechanics and Interactions
Health Sciences › Medicine › Surgery › Tissue Engineering and Regenerative Medicine
Physical Sciences › Engineering › Biomedical Engineering › Bone Tissue Engineering Materials
Keywords: nanoscale surface patterning, cell-material interactions, cell behavior control, surface topography, surface chemistry, biomedical implants, tissue regeneration, 3D scaffolds
MeSH terms: Animals, Biocompatible Materials, Cell Membrane, Cell Physiological Phenomena, Extracellular Matrix, Forecasting, Humans, Surface Properties, Tissue Engineering, Nanotechnology

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Exploring and Engineering the Cell Surface Interface

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