The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
A Mitotic Septin Scaffold Required for Mammalian Chromosome Congression and Segregation
Open accessAbstract
Coordination of cytokinesis with chromosome congression and segregation is critical for proper cell division, but the mechanism is unknown. Here, septins, a conserved family of polymerizing guanosine triphosphate–binding proteins, localized to the metaphase plate during mitosis. Septin depletion resulted in chromosome loss from the metaphase plate, lack of chromosome segregation and spindle elongation, and incomplete cytokinesis upon delayed mitotic exit. These defects correlated with loss of the mitotic motor and the checkpoint regulator centromere-associated protein E (CENP-E) from the kinetochores of congressing chromosomes. Mammalian septins may thus form a mitotic scaffold for CENP-E and other effectors to coordinate cytokinesis with chromosome congression and segregation.
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Cites
Cleveland, D. W., Mao, Y., & Sullivan, K. F. (2003) · Cell · doi:10.1016/s0092-8674(03)00115-6 · Cited by 1,003
Association of Spindle Assembly Checkpoint Component XMAD2 with Unattached Kinetochores
Chen, R.-H., Waters, J. C., Salmon, E. D., & Murray, A. W. (1996) · Science · doi:10.1126/science.274.5285.242 · Cited by 783
Self- and actin-templated assembly of Mammalian septins
Kinoshita, M., Field, C. M., Coughlin, M. L., Straight, A. F., & Mitchison, T. J. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00366-0 · Cited by 526
Self-citationThe septins: roles in cytokinesis and other processes
Longtine, M. S., DeMarini, D. J., Valencik, M. L., Al-Awar, O. S., Fares, H., De Virgilio, C., & Pringle, J. R. (1996) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(96)80054-8 · Cited by 504
CENP-E is a putative kinetochore motor that accumulates just before mitosis
Yen, T. J., Li, G., Schaar, B. T., Szilak, I., & Cleveland, D. W. (1992) · Nature · doi:10.1038/359536a0 · Cited by 429
Kinoshita, M., Kumar, S., Mizoguchi, A., Ide, C., Kinoshita, A., Haraguchi, T., Hiraoka, Y., & Noda, M. (1997) · Genes & Development · doi:10.1101/gad.11.12.1535 · Cited by 380
Self-citationLippincott, J., & Li, R. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.140.2.355 · Cited by 377
Unstable Kinetochore-Microtubule Capture and Chromosomal Instability Following Deletion of CENP-E
Putkey, F. R., Cramer, T., Morphew, M. K., Silk, A. D., Johnson, R. S., McIntosh, J. R., & Cleveland, D. W. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00255-1 · Cited by 329
The septin cortex at the yeast motherâbud neck
Gladfelter, A. (2001) · Current Opinion in Microbiology · doi:10.1016/s1369-5274(01)00269-7 · Cited by 329
The pathobiology of the septin gene family
Hall, P. A., & Russell, S. H. (2004) · The Journal of Pathology · doi:10.1002/path.1654 · Cited by 323
Cited by
Distinct roles of septins in cytokinesis: SEPT9 mediates midbody abscission
Estey, M. P., Di Ciano-Oliveira, C., Froese, C. D., Bejide, M. T., & Trimble, W. S. (2010) · Journal of Cell Biology · doi:10.1083/jcb.201006031 · Cited by 231
Tumor Treating Fields Perturb the Localization of Septins and Cause Aberrant Mitotic Exit
Gera, N., Yang, A., Holtzman, T. S., Lee, S. X., Wong, E. T., & Swanson, K. D. (2015) · PLOS ONE · doi:10.1371/journal.pone.0125269 · Cited by 217
Tooley, A. J., Gilden, J., Jacobelli, J., Beemiller, P., Trimble, W. S., Kinoshita, M., & Krummel, M. F. (2009) · Nature Cell Biology · doi:10.1038/ncb1808 · Cited by 189
“This result was specific for septin 7 knockdown ( septin 7 KD ), as the reciprocal was not observed when other septins were targeted, supporting the hypothesis that septin 7 is crucial for septin assembl”
Self-citationBowen, J. R., Hwang, D., Bai, X., Roy, D., & Spiliotis, E. T. (2011) · Journal of Cell Biology · doi:10.1083/jcb.201102076 · Cited by 143
Self-citationThe septin cytoskeleton facilitates membrane retraction during motility and blebbing
Gilden, J. K., Peck, S., M. Chen, Y.-C., & Krummel, M. F. (2012) · Journal of Cell Biology · doi:10.1083/jcb.201105127 · Cited by 113
Metadata
- Authors
- Spiliotis, E. T., Kinoshita, M., & Nelson, W. J.
- Venue
- Science
- Published
- 2005-03-18
- Volume
- 307
- Issue
- 5716
- Pages
- 1781-1785
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2093325895
- Cited by
- 256
- References
- 27
- FWCI
- 6.18
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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