The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Appendage Regeneration in Adult Vertebrates and Implications for Regenerative Medicine
Abstract
The regeneration of complex structures in adult salamanders depends on mechanisms that offer pointers for regenerative medicine. These include the plasticity of differentiated cells and the retention in regenerative cells of local cues such as positional identity. Limb regeneration proceeds by the local formation of a blastema, a growth zone of mesenchymal stem cells on the stump. The blastema can regenerate autonomously as a self-organizing system over variable linear dimensions. Here we consider the prospects for limb regeneration in mammals from this viewpoint.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation
Dor, Y., Brown, J., Martinez, O. I., & Melton, D. A. (2004) · Nature · doi:10.1038/nature02520 · Cited by 2,219
Liver regeneration: from myth to mechanism
Taub, R. (2004) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1489 · Cited by 1,567
Tissue-engineered bone regeneration
Petite, H., Viateau, V., Bensaïd, W., Meunier, A., de Pollak, C., Bourguignon, M., Oudina, K., Sedel, L., & Guillemin, G. (2000) · Nature Biotechnology · doi:10.1038/79449 · Cited by 1,475
Cited by
Macrophages are required for adult salamander limb regeneration
Godwin, J. W., Pinto, A. R., & Rosenthal, N. A. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1300290110 · Cited by 829
Stem cells, ageing and the quest for immortality
Rando, T. A. (2006) · Nature · doi:10.1038/nature04958 · Cited by 695
Hypoxia Tolerance in Reptiles, Amphibians, and Fishes: Life with Variable Oxygen Availability
Bickler, P. E., & Buck, L. T. (2007) · Annual Review of Physiology · doi:10.1146/annurev.physiol.69.031905.162529 · Cited by 687
Cardiac Myocyte Cell Cycle Control in Development, Disease, and Regeneration
Ahuja, P., Sdek, P., & MacLellan, W. R. (2007) · Physiological Reviews · doi:10.1152/physrev.00032.2006 · Cited by 568
The development of a bioengineered organ germ method
Nakao, K., Morita, R., Saji, Y., Ishida, K., Tomita, Y., Ogawa, M., Saitoh, M., Tomooka, Y., & Tsuji, T. (2007) · Nature Methods · doi:10.1038/nmeth1012 · Cited by 543
Metadata
- Authors
- Brockes, J. P., & Kumar, A.
- Venue
- Science
- Published
- 2005-12-23
- Volume
- 310
- Issue
- 5756
- Pages
- 1919-1923
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2067056216
- Cited by
- 371
- References
- 3
- FWCI
- 9.45
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Appendage Regeneration in Adult Vertebrates and Implications for Regenerative Medicine. https://app.cochat.ai/papers/10.1126/science.1115200
- The paper
- Brockes, J. P., & Kumar, A. (2005). Appendage Regeneration in Adult Vertebrates and Implications for Regenerative Medicine. Science. https://doi.org/10.1126/science.1115200
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.