The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Odorant ReceptorDerived cAMP Signals Direct Axonal Targeting
Abstract
In mammals, odorant receptors (ORs) direct the axons of olfactory sensory neurons (OSNs) toward targets in the olfactory bulb. We show that cyclic adenosine monophosphate (cAMP) signals that regulate the expression of axon guidance molecules are essential for the OR-instructed axonal projection. Genetic manipulations of ORs, stimulatory G protein, cAMP-dependent protein kinase, and cAMP response element–binding protein shifted the axonal projection sites along the anteriorposterior axis in the olfactory bulb. Thus, it is the OR-derived cAMP signals, rather than direct action of OR molecules, that determine the target destinations of OSNs.
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Cites
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Glutamic acid-113 serves as the retinylidene Schiff base counterion in bovine rhodopsin.
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Luo, L. (2021) · Science · doi:10.1126/science.abg7285 · Cited by 390
Semaphorin Regulation of Cellular Morphology
Tran, T. S., Kolodkin, A. L., & Bharadwaj, R. (2007) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.22.010605.093554 · Cited by 388
Super-Resolution Mapping of Neuronal Circuitry With an Index-Optimized Clearing Agent
Ke, M.-T., Nakai, Y., Fujimoto, S., Takayama, R., Yoshida, S., Kitajima, T. S., Sato, M., & Imai, T. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.02.057 · Cited by 264
Self-citationSemaphorin signalling during development
Jongbloets, B. C., & Pasterkamp, R. J. (2014) · Development · doi:10.1242/dev.105544 · Cited by 205
BIG-2 Mediates Olfactory Axon Convergence to Target Glomeruli
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Metadata
- Authors
- Imai, T., Suzuki, M., & Sakano, H.
- Venue
- Science
- Published
- 2006-10-27
- Volume
- 314
- Issue
- 5799
- Pages
- 657-661
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2055958441
- Cited by
- 329
- References
- 27
- FWCI
- 9.60
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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