The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
A Plasminogen-Activating Protease Specifically Controls the Development of Primary Pneumonic Plague
Abstract
Primary pneumonic plague is transmitted easily, progresses rapidly, and causes high mortality, but the mechanisms by which Yersinia pestis overwhelms the lungs are largely unknown. We show that the plasminogen activator Pla is essential for Y. pestis to cause primary pneumonic plague but is less important for dissemination during pneumonic plague than during bubonic plague. Experiments manipulating its temporal expression showed that Pla allows Y. pestis to replicate rapidly in the airways, causing a lethal fulminant pneumonia; if unexpressed, inflammation is aborted, and lung repair is activated. Inhibition of Pla expression prolonged the survival of animals with the disease, offering a therapeutic option to extend the period during which antibiotics are effective.
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Cites
Yersinia pestis--etiologic agent of plague
Perry, R. D., & Fetherston, J. D. (1997) · Clinical Microbiology Reviews · doi:10.1128/cmr.10.1.35 · Cited by 1,919
Lutz, R. (1997) · Nucleic Acids Research · doi:10.1093/nar/25.6.1203 · Cited by 1,693
Genome sequence of Yersinia pestis, the causative agent of plague
Parkhill, J., Wren, B. W., Thomson, N. R., Titball, R. W., Holden, M. T. G., Prentice, M. B., Sebaihia, M., James, K. D., Churcher, C., Mungall, K. L., et al. (2001) · Nature · doi:10.1038/35097083 · Cited by 1,243
Plague as a Biological Weapon: Medical and Public Health Management
Inglesby, T. V., Dennis, D. T., Henderson, D. A., Bartlett, J. G., Ascher, M. S., Eitzen, E., Fine, A. D., Friedlander, A. M., Hauer, J., Koerner, J. F., et al. (2000) · JAMA · doi:10.1001/jama.283.17.2281 · Cited by 997
YERSINIA OUTER PROTEINS: Role in Modulation of Host Cell Signaling Responses and Pathogenesis
Viboud, G. I., & Bliska, J. B. (2005) · Annual Review of Microbiology · doi:10.1146/annurev.micro.59.030804.121320 · Cited by 600
A Surface Protease and the Invasive Character of Plague
Sodeinde, O. A., Subrahmanyam, Y. V. B. K., Stark, K., Quan, T., Bao, Y., & Goguen, J. D. (1992) · Science · doi:10.1126/science.1439793 · Cited by 503
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Self-citationCelis, J. E., Madsen, P., Celis, A., Nielsen, H. V., & Gesser, B. (1987) · FEBS Letters · doi:10.1016/0014-5793(87)80865-7 · Cited by 193
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The multifaceted role of fibrinogen in tissue injury and inflammation
Luyendyk, J. P., Schoenecker, J. G., & Flick, M. J. (2019) · Blood · doi:10.1182/blood-2018-07-818211 · Cited by 555
The NLRP12 Inflammasome Recognizes Yersinia pestis
Vladimer, G. I., Weng, D., Paquette, S. W. M., Vanaja, S. K., Rathinam, V. A. K., Aune, M. H., Conlon, J. E., Burbage, J. J., Proulx, M. K., Liu, Q., et al. (2012) · Immunity · doi:10.1016/j.immuni.2012.07.006 · Cited by 366
Mechanisms of Severe Acute Respiratory Syndrome Coronavirus-Induced Acute Lung Injury
Gralinski, L. E., Bankhead, A., Jeng, S., Menachery, V. D., Proll, S., Belisle, S. E., Matzke, M., Webb-Robertson, B.-J. M., Luna, M. L., Shukla, A. K., et al. (2013) · mBio · doi:10.1128/mbio.00271-13 · Cited by 310
Corruption of Innate Immunity by Bacterial Proteases
Potempa, J., & Pike, R. N. (2009) · Journal of Innate Immunity · doi:10.1159/000181144 · Cited by 276
Gandotra, S., Schnappinger, D., Monteleone, M., Hillen, W., & Ehrt, S. (2007) · Nature Medicine · doi:10.1038/nm1683 · Cited by 254
Metadata
- Authors
- Lathem, W. W., Price, P. A., Miller, V. L., & Goldman, W. E.
- Venue
- Science
- Published
- 2007-01-26
- Volume
- 315
- Issue
- 5811
- Pages
- 509-513
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2006130551
- Cited by
- 275
- References
- 18
- FWCI
- 13.06
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
