The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
An Evolutionarily Conserved Mechanism Delimiting SHR Movement Defines a Single Layer of Endodermis in Plants
Abstract
Intercellular protein movement plays a critical role in animal and plant development. SHORTROOT (SHR) is a moving transcription factor essential for endodermis specification in the Arabidopsis root. Unlike diffusible animal morphogens, which form a gradient across multiple cell layers, SHR movement is limited to essentially one cell layer. However, the molecular mechanism is unknown. We show that SCARECROW (SCR) blocks SHR movement by sequestering it into the nucleus through protein-protein interaction and a safeguard mechanism that relies on a SHR/SCR-dependent positive feedback loop for SCR transcription. Our studies with SHR and SCR homologs from rice suggest that this mechanism is evolutionarily conserved, providing a plausible explanation why nearly all plants have a single layer of endodermis.
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Kitano, H. (2004) · Nature Reviews Genetics · doi:10.1038/nrg1471 · Cited by 2,278
Di Laurenzio, L., Wysocka-Diller, J., Malamy, J. E., Pysh, L., Helariutta, Y., Freshour, G., Hahn, M. G., Feldmann, K. A., & Benfey, P. N. (1996) · Cell · doi:10.1016/s0092-8674(00)80115-4 · Cited by 1,124
Self-citation
Cited by
Cell Signalling by MicroRNA165/6 Directs Gene Dose-Dependent Root Cell Fate
Carlsbecker, A., Lee, J.-Y., Roberts, C. J., Dettmer, J., Lehesranta, S., Zhou, J., Lindgren, O., Moreno-Risueno, M. A., Vatén, A., Thitamadee, S., et al. (2010) · Nature · doi:10.1038/nature08977 · Cited by 861
Self-citationGlobal Analysis of DELLA Direct Targets in Early Gibberellin Signaling in Arabidopsis
Zentella, R., Zhang, Z.-L., Park, M., Thomas, S. G., Endo, A., Murase, K., Fleet, C. M., Jikumaru, Y., Nambara, E., Kamiya, Y., et al. (2007) · The Plant Cell · doi:10.1105/tpc.107.054999 · Cited by 678
Hirsch, S., Kim, J., Muñoz, A., Heckmann, A. B., Downie, J. A., & Oldroyd, G. E. D. (2009) · The Plant Cell · doi:10.1105/tpc.108.064501 · Cited by 448
Spatiotemporal regulation of cell-cycle genes by SHORTROOT links patterning and growth
Sozzani, R., Cui, H., Moreno-Risueno, M. A., Busch, W., Van Norman, J. M., Vernoux, T., Brady, S. M., Dewitte, W., Murray, J. A. H., & Benfey, P. N. (2010) · Nature · doi:10.1038/nature09143 · Cited by 438
Self-citationda Costa, C. T., de Almeida, M. R., Ruedell, C. M., Schwambach, J., Maraschin, F. S., & Fett-Neto, A. G. (2013) · Frontiers in Plant Science · doi:10.3389/fpls.2013.00133 · Cited by 417
Metadata
- Authors
- Cui, H., Levesque, M. P., Vernoux, T., Jung, J. W., Paquette, A. J., Gallagher, K. L., Wang, J. Y., Blilou, I., Scheres, B., & Benfey, P. N.
- Venue
- Science
- Published
- 2007-04-20
- Volume
- 316
- Issue
- 5823
- Pages
- 421-425
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2027577154
- Cited by
- 600
- References
- 2
- FWCI
- 30.03
- Type
- journal article
- Language
- en
- Open access
- closed
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- Cui, H., Levesque, M. P., Vernoux, T., Jung, J. W., Paquette, A. J., Gallagher, K. L., Wang, J. Y., Blilou, I., Scheres, B., & Benfey, P. N. (2007). An Evolutionarily Conserved Mechanism Delimiting SHR Movement Defines a Single Layer of Endodermis in Plants. Science. https://doi.org/10.1126/science.1139531
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