Restriction of an Extinct Retrovirus by the Human TRIM5α Antiviral Protein

The cytoplasmic body component TRIM5α restricts HIV-1 infection in Old World monkeys

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Chimpanzee Reservoirs of Pandemic and Nonpandemic HIV-1

Keele, B. F., Heuverswyn, F. V., Li, Y., Bailes, E., Takehisa, J., Santiago, M. L., Bibollet‐Ruche, F., Chen, Y., Wain, L. V., Liégeois, F., et al. (2006) · Science · doi:10.1126/science.1126531 · Cited by 955

Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5α restriction factor

Stremlau, M. H., Perron, M. J., Lee, M. N., Li, Y., Song, B., Javanbakht, H., Diaz‐Griffero, F., Anderson, D. J., Sundquist, W. I., & Sodroski, J. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0509996103 · Cited by 736

Positive selection of primate TRIM5 α identifies a critical species-specific retroviral restriction domain

Sawyer, S. L., Wu, L. I., Emerman, M., & Malik, H. S. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409853102 · Cited by 688

Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G

Sawyer, S. L., Emerman, M., & Malik, H. S. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020275 · Cited by 485

A Single Amino Acid Change in the SPRY Domain of Human Trim5α Leads to HIV-1 Restriction

Yap, M. W., Nisole, S., & Stoye, J. P. (2005) · Current Biology · doi:10.1016/j.cub.2004.12.042 · Cited by 408

SIV infection in wild gorillas

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Species-Specific Variation in the B30.2(SPRY) Domain of TRIM5α Determines the Potency of Human Immunodeficiency Virus Restriction

Stremlau, M. H., Perron, M. J., Welikala, S., & Sodroski, J. (2005) · Journal of Virology · doi:10.1128/jvi.79.5.3139-3145.2005 · Cited by 372

Retrovirus resistance factors Ref1 and Lv1 are species-specific variants of TRIM5α

Hatziioannou, T., Pérez-Caballero, D., Yang, A., Cowan, S., & Bieniasz, P. D. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402361101 · Cited by 371

Reconstitution of an Infectious Human Endogenous Retrovirus

Lee, Y. N., & Bieniasz, P. D. (2007) · PLoS Pathogens · doi:10.1371/journal.ppat.0030010 · Cited by 311

Endogenous viruses: insights into viral evolution and impact on host biology

Feschotte, C., & Gilbert, C. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3199 · Cited by 918

Rules of engagement: molecular insights from host–virus arms races

Daugherty, M. D., & Malik, H. S. (2012) · Annual Review of Genetics · doi:10.1146/annurev-genet-110711-155522 · Cited by 515

Effects of Retroviruses on Host Genome Function

Jern, P., & Coffin, J. M. (2008) · Annual Review of Genetics · doi:10.1146/annurev.genet.42.110807.091501 · Cited by 499

Origins and evolutionary consequences of ancient endogenous retroviruses

Johnson, W. E. (2019) · Nature Reviews Microbiology · doi:10.1038/s41579-019-0189-2 · Cited by 425

High-resolution comparative analysis of great ape genomes

Kronenberg, Z. N., Fiddes, I. T., Gordon, D., Murali, S., Cantsilieris, S., Meyerson, O. S., Underwood, J. G., Nelson, B. J., Chaisson, M. J. P., Dougherty, M. L., et al. (2018) · Science · doi:10.1126/science.aar6343 · Cited by 350

Evolutionary insights into host–pathogen interactions from mammalian sequence data

Sironi, M., Cagliani, R., Forni, D., & Clerici, M. (2015) · Nature Reviews Genetics · doi:10.1038/nrg3905 · Cited by 302

Protein kinase R reveals an evolutionary model for defeating viral mimicry

Elde, N. C., Child, S. J., Geballe, A. P., & Malik, H. S. (2009) · Nature · doi:10.1038/nature07529 · Cited by 260

Dynamic control of endogenous retroviruses during development

Rowe, H. M., & Trono, D. (2011) · Virology · doi:10.1016/j.virol.2010.12.007 · Cited by 291

The Developmental Control of Transposable Elements and the Evolution of Higher Species

Friedli, M., & Trono, D. (2015) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-100814-125514 · Cited by 274

Intracellular Nucleic Acid Detection in Autoimmunity

Crowl, J. T., Gray, E. E., Pestal, K., Volkman, H. E., & Stetson, D. B. (2017) · Annual Review of Immunology · doi:10.1146/annurev-immunol-051116-052331 · Cited by 222

The evolutionary conundrum of pathogen mimicry

Elde, N. C., & Malik, H. S. (2009) · Nature Reviews Microbiology · doi:10.1038/nrmicro2222 · Cited by 214

Analyzing protein structure and function using ancestral gene reconstruction

Harms, M. J., & Thornton, J. W. (2010) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2010.03.005 · Cited by 214

A transitional endogenous lentivirus from the genome of a basal primate and implications for lentivirus evolution

Gifford, R. J., Katzourakis, A., Tristem, M., Pybus, O. G., Winters, M. A., & Shafer, R. W. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0807873105 · Cited by 210

Tripartite motif‐containing 22 inhibits the activity of hepatitis B virus core promoter, which is dependent on nuclear‐located RING domain†

Gao, B., Duan, Z., Xu, W., & Xiong, S. (2009) · Hepatology · doi:10.1002/hep.23011 · Cited by 207

The artiodactyl APOBEC3 innate immune repertoire shows evidence for a multi-functional domain organization that existed in the ancestor of placental mammals

LaRue, R. S., Jönsson, S., Silverstein, K. A. T., Lajoie, M., Bertrand, D., El-Mabrouk, N., Hötzel, I., Andrésdóttir, V., Smith, T. P. L., & Harris, R. S. (2008) · BMC Molecular Biology · doi:10.1186/1471-2199-9-104 · Cited by 196

Paleovirology—Modern Consequences of Ancient Viruses

Emerman, M., & Malik, H. S. (2010) · PLoS Biology · doi:10.1371/journal.pbio.1000301 · Cited by 192

Discordant Evolution of the Adjacent Antiretroviral Genes TRIM22 and TRIM5 in Mammals

Sawyer, S. L., Emerman, M., & Malik, H. S. (2007) · PLoS Pathogens · doi:10.1371/journal.ppat.0030197 · Cited by 181

TRIMCyp expression in Old World primates Macaca nemestrina and Macaca fascicularis

Brennan, G., Kozyrev, Y., & Hu, S.-L. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0709511105 · Cited by 171

Human uniqueness: genome interactions with environment, behaviour and culture

Varki, A. P., Geschwind, D. H., & Eichler, E. E. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2428 · Cited by 172

Deficiency in ubiquitin ligase TRIM2 causes accumulation of neurofilament light chain and neurodegeneration

Balaštík, M., Ferraguti, F., Pires‐daSilva, A., Lee, T. H., Álvarez-Bolado, G., Lu, K. P., & Gruß, P. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0802261105 · Cited by 151

Endogenous retroviruses: acquisition, amplification and taming of genome invaders

Dewannieux, M., & Heidmann, T. (2013) · Current Opinion in Virology · doi:10.1016/j.coviro.2013.08.005 · Cited by 141

Paleovirology—ghosts and gifts of viruses past

Patel, M. R., Emerman, M., & Malik, H. S. (2011) · Current Opinion in Virology · doi:10.1016/j.coviro.2011.06.007 · Cited by 139

Two-stepping through time: mammals and viruses

Meyerson, N. R., & Sawyer, S. L. (2011) · Trends in Microbiology · doi:10.1016/j.tim.2011.03.006 · Cited by 133

Activation of the innate immune response by endogenous retroviruses

Hurst, T. P., & Magiorkinis, G. (2014) · Journal of General Virology · doi:10.1099/jgv.0.000017 · Cited by 146

Endogenous Retroviruses in the Genomics Era

Johnson, W. E. (2015) · Annual Review of Virology · doi:10.1146/annurev-virology-100114-054945 · Cited by 126

Human transposable elements in Repbase: genomic footprints from fish to humans

Kojima, K. K. (2018) · Mobile DNA · doi:10.1186/s13100-017-0107-y · Cited by 125

Role of retroviral restriction factors in the interferon-α–mediated suppression of HIV-1 in vivo

Pillai, S. K., Abdel‐Mohsen, M., Guatelli, J., Skasko, M., Monto, A., Fujimoto, K., Yukl, S. A., Greene, W. C., Kovari, H., Rauch, A., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1111573109 · Cited by 118

Identification of a Genomic Reservoir for New TRIM Genes in Primate Genomes

Han, K., Lou, D. I., & Sawyer, S. L. (2011) · PLoS Genetics · doi:10.1371/journal.pgen.1002388 · Cited by 120

Molecular evolution of the antiretroviral TRIM5 gene

Johnson, W. E., & Sawyer, S. L. (2009) · Immunogenetics · doi:10.1007/s00251-009-0358-y · Cited by 118

Co-option of an endogenous retrovirus envelope for host defense in hominid ancestors

Blanco-Melo, D., Gifford, R. J., & Bieniasz, P. D. (2017) · eLife · doi:10.7554/elife.22519 · Cited by 109

Robustness of Reconstructed Ancestral Protein Functions to Statistical Uncertainty

Eick, G. N., Bridgham, J. T., Anderson, D. P., Harms, M. J., & Thornton, J. W. (2016) · Molecular Biology and Evolution · doi:10.1093/molbev/msw223 · Cited by 103

Transmission, Evolution, and Endogenization: Lessons Learned from Recent Retroviral Invasions

Greenwood, A. D., Ishida, Y., O’Brien, S. P., Roca, A. L., & Eiden, M. V. (2017) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00044-17 · Cited by 110

Trans-species polymorphism in humans and the great apes is generally maintained by balancing selection that modulates the host immune response

Azevedo, L., Serrano, C., Amorim, A., & Cooper, D. N. (2015) · Human Genomics · doi:10.1186/s40246-015-0043-1 · Cited by 89

Structure of the rhesus monkey TRIM5α PRYSPRY domain, the HIV capsid recognition module

Biris, N., Yang, Y., Taylor, A. B., Tomashevski, A., Guo, M., Hart, P. J., Diaz‐Griffero, F., & Ivanov, D. N. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1203536109 · Cited by 91

Innate Antiviral Immune Signaling, Viral Evasion and Modulation by HIV-1

Rustagi, A., & Gale, M. (2013) · Journal of Molecular Biology · doi:10.1016/j.jmb.2013.12.003 · Cited by 92

Are human endogenous retroviruses pathogenic? An approach to testing the hypothesis

Young, G. R., Stoye, J. P., & Kassiotis, G. (2013) · BioEssays · doi:10.1002/bies.201300049 · Cited by 78

TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation

Chiramel, A. I., Meyerson, N. R., McNally, K. L., Broeckel, R. M., Montoya, V. R., Méndez-Solís, O., Robertson, S. J., Sturdevant, G. L., Lubick, K. J., Nair, V., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.05.040 · Cited by 78

Alignment Modulates Ancestral Sequence Reconstruction Accuracy

Vialle, R. A., Tamuri, A. U., & Goldman, N. (2018) · Molecular Biology and Evolution · doi:10.1093/molbev/msy055 · Cited by 75

Is the high virulence of HIV-1 an unfortunate coincidence of primate lentiviral evolution?

Kirchhoff, F. (2009) · Nature Reviews Microbiology · doi:10.1038/nrmicro2111 · Cited by 77

Gorilla genome structural variation reveals evolutionary parallelisms with chimpanzeePreprint

Ventura, M., Catacchio, C. R., Alkan, C., Marquès‐Bonet, T., Sajjadian, S., Graves, T., Hormozdiari, F., Navarro, A., Malig, M., Baker, C. A., et al. (2011) · Genome Research · doi:10.1101/gr.124461.111 · Cited by 76

How Samhd1 changes our view of viral restriction

Laguette, N., & Benkirane, M. (2011) · Trends in Immunology · doi:10.1016/j.it.2011.11.002 · Cited by 81

An expanded clade of rodent Trim5 genes

Tareen, S. U., Sawyer, S. L., Malik, H. S., & Emerman, M. (2009) · Virology · doi:10.1016/j.virol.2008.12.018 · Cited by 73

Generation of Infectious Molecular Clones of Simian Immunodeficiency Virus from Fecal Consensus Sequences of Wild Chimpanzees

Takehisa, J., Kraus, M. H., Decker, J. M., Li, Y., Keele, B. F., Bibollet‐Ruche, F., Zammit, K. P., Weng, Z., Santiago, M. L., Kamenya, S. M., et al. (2007) · Journal of Virology · doi:10.1128/jvi.00551-07 · Cited by 72

Anti‐retroviral activity of TRIM5α

Nakayama, E. E., & Shioda, T. (2010) · Reviews in Medical Virology · doi:10.1002/rmv.637 · Cited by 71

Evolution of the Retroviral Restriction Gene Fv1: Inhibition of Non-MLV Retroviruses

Yap, M. W., Colbeck, E. J., Ellis, S., & Stoye, J. P. (2014) · PLoS Pathogens · doi:10.1371/journal.ppat.1003968 · Cited by 69

Structural and Functional Analysis of Prehistoric Lentiviruses Uncovers an Ancient Molecular Interface

Goldstone, D. C., Yap, M. W., Robertson, L. E., Haire, L. F., Taylor, W. R., Katzourakis, A., Stoye, J. P., & Taylor, I. A. (2010) · Cell Host & Microbe · doi:10.1016/j.chom.2010.08.006 · Cited by 64

Sequencing Primate Genomes: What Have We Learned?

Marquès‐Bonet, T., Ryder, O. A., & Eichler, E. E. (2009) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.9.081307.164420 · Cited by 65

Long-term balancing selection maintains trans-specific polymorphisms in the human TRIM5 gene

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The decline of human endogenous retroviruses: extinction and survival

Magiorkinis, G., Blanco-Melo, D., & Belshaw, R. D. (2015) · Retrovirology · doi:10.1186/s12977-015-0136-x · Cited by 61

Nonhuman Primate Models for HIV/AIDS Vaccine Development

Sui, Y., Gordon, S. N., Franchini, G., & Berzofsky, J. A. (2013) · Current Protocols in Immunology · doi:10.1002/0471142735.im1214s102 · Cited by 61

Evolutionary Trajectories of Primate Genes Involved in HIV Pathogenesis

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Non-human Primate Schlafen11 Inhibits Production of Both Host and Viral Proteins

Stabell, A. C., Hawkins, J., Li, M., Gao, X., David, M., Press, W. H., & Sawyer, S. L. (2016) · PLoS Pathogens · doi:10.1371/journal.ppat.1006066 · Cited by 54

Human Endogenous Retrovirus K106 (HERV-K106) Was Infectious after the Emergence of Anatomically Modern Humans

Jha, A. R., Nixon, D. F., Rosenberg, M. G., Martin, J. N., Deeks, S. G., Hudson, R. R., Garrison, K. E., & Pillai, S. K. (2011) · PLoS ONE · doi:10.1371/journal.pone.0020234 · Cited by 48

OASes and STING: Adaptive Evolution in Concert

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Characterization of a core fragment of the rhesus monkey TRIM5α protein

Kar, A. K., Mao, Y., Bird, G. H., Walensky, L. D., & Sodroski, J. (2011) · BMC Biochemistry · doi:10.1186/1471-2091-12-1 · Cited by 46

Evidence for Restriction of Ancient Primate Gammaretroviruses by APOBEC3 but Not TRIM5α Proteins

Perez-Caballero, D., Soll, S. J., & Bieniasz, P. D. (2008) · PLoS Pathogens · doi:10.1371/journal.ppat.1000181 · Cited by 45

Birth, decay, and reconstruction of an ancient TRIMCyp gene fusion in primate genomes

Malfavon-Borja, R., Wu, L. I., Emerman, M., & Malik, H. S. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1216542110 · Cited by 43

Modeling Infectious Disease in Mice: Co-Adaptation and the Role of Host-Specific IFNγ Responses

Coers, J., Starnbach, M. N., & Howard, J. C. (2009) · PLoS Pathogens · doi:10.1371/journal.ppat.1000333 · Cited by 44

Determinants of cyclophilin A-dependent TRIM5α restriction against HIV-1

Lin, T., & Emerman, M. (2008) · Virology · doi:10.1016/j.virol.2008.06.037 · Cited by 35

Tripartite Motif (TRIM) 12c, a Mouse Homolog of TRIM5, Is a Ubiquitin Ligase That Stimulates Type I IFN and NF-κB Pathways along with TNFR-Associated Factor 6

Chang, T.-H., Yoshimi, R., & Ozato, K. (2015) · The Journal of Immunology · doi:10.4049/jimmunol.1402064 · Cited by 36

Stabilized Human TRIM5α Protects Human T Cells From HIV-1 Infection

Richardson, M. W., Guo, L., Xin, F., Yang, X., & Riley, J. L. (2014) · Molecular Therapy · doi:10.1038/mt.2014.52 · Cited by 39

Impact of Endogenous Intronic Retroviruses on Major Histocompatibility Complex Class II Diversity and Stability

Doxiadis, G. G. M., de Groot, N., & Bontrop, R. E. (2008) · Journal of Virology · doi:10.1128/jvi.00097-08 · Cited by 38

Collective Dynamics Differentiates Functional Divergence in Protein Evolution

Glembo, T. J., Farrell, D. W., Gerek, Z. N., Thorpe, M. F., & Ozkan, S. B. (2012) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1002428 · Cited by 34

TRIM5α and Species Tropism of HIV/SIV

Nakayama, E. E., & Shioda, T. (2012) · Frontiers in Microbiology · doi:10.3389/fmicb.2012.00013 · Cited by 39

Comparison of anti-viral activity of rhesus monkey and cynomolgus monkey TRIM5αs against human immunodeficiency virus type 2 infection

Kono, K., Song, H., Shingai, Y., Shioda, T., & Nakayama, E. E. (2008) · Virology · doi:10.1016/j.virol.2007.12.022 · Cited by 33

On the classification and evolution of endogenous retrovirus: human endogenous retroviruses may not be ‘human’ after all

Escalera‐Zamudio, M., & Greenwood, A. D. (2016) · Apmis · doi:10.1111/apm.12489 · Cited by 36

Multiple Epigenetic Modifiers Induce Aggressive Viral Extinction in Extraembryonic Endoderm Stem Cells

Golding, M. C., Zhang, L., & Mann, M. R. W. (2010) · Cell stem cell · doi:10.1016/j.stem.2010.03.014 · Cited by 35

Retroviruses of the RDR superinfection interference group: ancient origins and broad host distribution of a promiscuous Env gene

Sinha, A., & Johnson, W. E. (2017) · Current Opinion in Virology · doi:10.1016/j.coviro.2017.07.020 · Cited by 31

Antiretroviral Activity of Ancestral TRIM5α

Goldschmidt, V., Ciuffi, A., Ortiz, M., Brawand, D., Muñoz, M., Kaessmann, H., & Telenti, A. (2007) · Journal of Virology · doi:10.1128/jvi.01828-07 · Cited by 31

Heterogeneous susceptibility of circulating SIV isolate capsids to HIV-interacting factors

Mamede, J. I., Sitbon, M., Battini, J., & Courgnaud, V. (2013) · Retrovirology · doi:10.1186/1742-4690-10-77 · Cited by 32

Identification of Postentry Restrictions to Mason-Pfizer Monkey Virus Infection in New World Monkey Cells

Diehl, W. E., Stansell, E., Kaiser, S. M., Emerman, M., & Hunter, E. (2008) · Journal of Virology · doi:10.1128/jvi.00269-08 · Cited by 30

Porcine endogenous retroviruses PERV A and A/C recombinant are insensitive to a range of divergent mammalian TRIM5α proteins including human TRIM5α

Wood, A., Webb, B. L. J., Bartosch, B., Schaller, T., Takeuchi, Y., & Towers, G. J. (2009) · Journal of General Virology · doi:10.1099/vir.0.007377-0 · Cited by 31

Interfering Residues Narrow the Spectrum of MLV Restriction by Human TRIM5α

Maillard, P. V., Reynard, S., Serhan, F., Turelli, P., & Trono, D. (2007) · PLoS Pathogens · doi:10.1371/journal.ppat.0030200 · Cited by 29

Functional primate genomics—leveraging the medical potential

Enard, W. (2012) · Journal of Molecular Medicine · doi:10.1007/s00109-012-0901-4 · Cited by 30

Rapid Adversarial Co-Evolution of Viruses and Cellular Restriction Factors

Johnson, W. E. (2013) · Current topics in microbiology and immunology · doi:10.1007/978-3-642-37765-5_5 · Cited by 27

Host Genes Important to HIV Replication and EvolutionPreprint

Telenti, A., & Johnson, W. E. (2012) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a007203 · Cited by 26

Endogenous retroviruses and multiple sclerosis–new pieces to the puzzle

Nissen, K. K., Laska, M. J., Hansen, B. D., Terkelsen, T., Villesen, P., Bahrami, S., Petersen, T., Pedersen, F. S., & Nexø, B. A. (2013) · BMC Neurology · doi:10.1186/1471-2377-13-111 · Cited by 27

Evolutionary conflicts and adverse effects of antiviral factors

Sauter, D., & Kirchhoff, F. (2021) · eLife · doi:10.7554/elife.65243 · Cited by 26

Antiretroviral Therapy Down-Regulates Innate Antiviral Response Genes in Patients With AIDS in Sub-Saharan Africa

Boulware, D. R., Meya, D. B., Bergemann, T. L., Williams, D. A., Louis, I. V.-S., Rhein, J., Staddon, J. H., Kambugu, A., Janoff, E. N., & Bohjanen, P. R. (2010) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e3181ef4963 · Cited by 25

Associations between human TRIM22 gene expression and the response to combination therapy with Peg-IFNα-2a and ribavirin in Iranian patients with chronic hepatitis C

Sadeghi, F., Bokharaei‐Salim, F., Salehi-Vaziri, ‪., Monavari, S. H., Alavian, S. M., Salimi, S., Vahabpour, R., & Keyvani, H. (2014) · Journal of Medical Virology · doi:10.1002/jmv.23985 · Cited by 24

Animal models in virus research: their utility and limitations

Louz, D., Bergmans, H. E. N., Loos, B. P., & Hoeben, R. C. (2012) · Critical Reviews in Microbiology · doi:10.3109/1040841x.2012.711740 · Cited by 26

Mammalian NPC1 genes may undergo positive selection and human polymorphisms associate with type 2 diabetes

Al‐Daghri, N. M., Cagliani, R., Forni, D., Alokail, M. S., Pozzoli, U., Alkharfy, K. M., Sabico, S., Clerici, M., & Sironi, M. (2012) · BMC Medicine · doi:10.1186/1741-7015-10-140 · Cited by 26

Evolution of the Antiretroviral Restriction Factor TRIMCyp in Old World Primates

Dietrich, E. A., Jones‐Engel, L., & Hu, S.-L. (2010) · PLoS ONE · doi:10.1371/journal.pone.0014019 · Cited by 22

Reconstruction of a replication-competent ancestral murine endogenous retrovirus-L

Blanco-Melo, D., Gifford, R. J., & Bieniasz, P. D. (2018) · Retrovirology · doi:10.1186/s12977-018-0416-3 · Cited by 21

Evidence for selection at HIV host susceptibility genes in a West Central African human population

Zhao, K. X., Ishida, Y., Oleksyk, T. K., Winkler, C. A., & Roca, A. L. (2012) · BMC Evolutionary Biology · doi:10.1186/1471-2148-12-237 · Cited by 22

Role of Human TRIM5α in Intrinsic Immunity

Nakayama, E. E., & Shioda, T. (2012) · Frontiers in Microbiology · doi:10.3389/fmicb.2012.00097 · Cited by 22

Differential Expression of Tripartite Motif-Containing Family in Normal Human Dermal Fibroblasts in Response to Porcine Endogenous Retrovirus Infection

Kimsa, M. W., Strzałka‐Mrozik, B., Kimsa, M. C., Mazurek, U. M., Kruszniewska‐Rajs, C., Gola, J. M., Adamska, J., & Twardoch, M. (2014) · Folia Biologica · doi:10.14712/fb2014060030144 · Cited by 21

Daxx Inhibits HIV-1 Reverse Transcription and Uncoating in a SUMO-Dependent Manner

Maillet, S., Fernandez, J., Decourcelle, M., Koulali, K. E., Blanchet, F. P., Arhel, N. J., Maarifi, G., & Nisole, S. (2020) · Viruses · doi:10.3390/v12060636 · Cited by 23

High level of susceptibility to human TRIM5α conferred by HIV-2 capsid sequences

Takeuchi, J. S., Perche, B., Migraine, J., Mercier‐Delarue, S., Ponscarme, D., Simon, F., Clavel, F., & Labrosse, B. (2013) · Retrovirology · doi:10.1186/1742-4690-10-50 · Cited by 20

Applied & translational genomics

ScienceDirect (2012) · Cited by 20

The phytochelatin synthase gene in date palm ( Phoenix dactylifera L.): Phylogeny, evolution and expression

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Disease consequences of human adaptation

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Schlafen 5 suppresses human immunodeficiency virus type 1 transcription by commandeering cellular epigenetic machinery

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A contaminant-free assessment of Endogenous Retroviral RNA in human plasma

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Zebrafish-based platform for emerging bio-contaminants and virus inactivation research

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TRIM5α recruits HDAC1 to p50 and Sp1 and promotes H3K9 deacetylation at the HIV-1 LTR

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Antiretroviral Activity of Ancestral TRIM5α

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Retrovirus Restriction by TRIM5α Variants from Old World and New World Primates

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Isolation of an Active Lv1 Gene from Cattle Indicates that Tripartite Motif Protein-Mediated Innate Immunity to Retroviral Infection Is Widespread among Mammals

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