Replication of Genome-Wide Association Signals in UK Samples Reveals Risk Loci for Type 2 Diabetes
Zeggini, Eleftheria, Weedon, Michael N., Lindgren, Cecilia M., Frayling, Timothy M., Elliott, Katherine S., Lango, Hana, Timpson, Nicholas J., Perry, John R. B. +18 more·2007·Science
Cited by (1,003)
Items 101–200 of 1,003
- Gene Ontology Analysis of GWA Study Data Sets Provides Insights into the Biology of Bipolar DisorderHolmans, Peter, Green, Elaine K., Pahwa, Jaspreet Singh, Ferreira, Manuel A.R., Purcell, Shaun M., Sklar, Pamela, Owen, Michael J., O'Donovan, Michael C., Craddock, Nick · 2009 · The American Journal of Human Genetics
- A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibilityKeller, Mark P., Choi, YounJeong, Wang, Ping, Belt Davis, Dawn, Rabaglia, Mary E., Oler, Angie T., Stapleton, Donald S., Argmann, Carmen, Schueler, Kathy L., Edwards, Steve et al. · 2008 · Genome Research
- Insulin Storage and Glucose Homeostasis in Mice Null for the Granule Zinc Transporter ZnT8 and Studies of the Type 2 Diabetes–Associated VariantsTamara J. Nicolson, Elisa A. Bellomo, Nadeeja Wijesekara, Merewyn K. Loder, Jocelyn M. Baldwin, Armen V. Gyulkhandanyan, Vasilij Koshkin, Andrei I. Tarasov, Raffaella Carzaniga, Katrin Kronenberger et al. · 2009 · Diabetes
- Validating, augmenting and refining genome-wide association signalsJohn P. A. Ioannidis, Gilles D. Thomas, Mark J. Daly · 2009 · Nature Reviews Genetics
- Concept, Design and Implementation of a Cardiovascular Gene-Centric 50 K SNP Array for Large-Scale Genomic Association StudiesBrendan J. Keating, Sam E. Tischfield, Sarah Shaw Murray, Tushar Bhangale, Thomas S. Price, Joseph Glessner, Luana Galver, Jeffrey C. Barrett, Struan F.A. Grant, Deborah Farlow et al. · 2008 · PLoS ONE
- Type 2 diabetes mellitus and cardiovascular disease: Genetic and epigenetic linksDe Rosa, Salvatore, Arcidiacono, Biagio, Chiefari, Eusebio, Brunetti, Antonio, Indolfi, Ciro, Foti, Daniela P. · 2018 · Frontiers in Endocrinology
- Common pathological processes in Alzheimer disease and type 2 diabetes: A reviewLi, Lin, Hölscher, Christian · 2007 · Brain Research Reviews
- Polycomb protein Ezh2 regulates pancreatic β-cell <i>Ink4a/Arf</i> expression and regeneration in diabetes mellitusChen, Hainan, Gu, Xueying, Su, I-hsin, Bottino, Rita, Contreras, Juan L., Tarakhovsky, Alexander, Kim, Seung K. · 2009 · Genes & Development
- Implication of Genetic Variants Near <i>TCF7L2</i>, <i>SLC30A8</i>, <i>HHEX</i>, <i>CDKAL1</i>, <i>CDKN2A/B</i>, <i>IGF2BP2</i>, and <i>FTO</i> in Type 2 Diabetes and Obesity in 6,719 AsiansNg, Maggie C.Y., Park, Kyong Soo, Oh, Bermseok, Tam, Claudia H.T., Cho, Young Min, Shin, Hyoung Doo, Lam, Vincent K.L., Ma, Ronald C.W., So, Wing Yee, Cho, Yoon Shin et al. · 2008 · Diabetes
- Association between a literature-based genetic risk score and cardiovascular events in womenPaynter, Nina P. · 2010 · JAMA
- Expansion of β-cell mass in response to pregnancyRieck, Sebastian, Kaestner, Klaus H. · 2010 · Trends in Endocrinology & Metabolism
- Progress and challenges in genome-wide association studies in humansPeter Donnelly · 2008 · Nature
- The link between family history and risk of type 2 diabetes is not explained by anthropometric, lifestyle or genetic risk factors: the EPIC-InterAct studyThe InterAct Consortium (614230) · 2012 · Diabetologia
- Genomewide association for schizophrenia in the CATIE study: results of stage 1Patrick F. Sullivan, Danyu Y. Lin, Jung‐Ying Tzeng, Edwin J. C. G. van den Oord, Diana O. Perkins, T. Scott Stroup, Michael J. Wagner, Seonjoo Lee, Fred A. Wright, Fei Zou et al. · 2008 · Molecular Psychiatry
- Genome-wide association studies: potential next steps on a genetic journeyMark I. McCarthy, Joel N. Hirschhorn · 2008 · Human Molecular Genetics
- A Type 1 Diabetes Genetic Risk Score Can Aid Discrimination Between Type 1 and Type 2 Diabetes in Young AdultsRichard A. Oram, Kashyap Patel, Anita Hill, Beverley M. Shields, Timothy James McDonald, Angus G. Jones, Andrew Tym Hattersley, Michael N. Weedon · 2015 · Diabetes Care
- STrengthening the REporting of Genetic Association Studies (STREGA)—an extension of the STROBE statementJulian Little, Julian P. T. Higgins, John P. A. Ioannidis, David Moher, France Gagnon, Erik B von Elm, Muin J. Khoury, Barbara J. Cohen, George Davey Smith, Jeremy Grimshaw et al. · 2009 · Genetic Epidemiology
- Molecular Signatures of Obstructive Sleep Apnea in Adults: A Review and PerspectiveErna Sif Arnardóttir, Mirosław Mackiewicz, Þórarinn Gíslason, Karen L. Teff, Allan I Pack · 2009 · SLEEP
- A Genome-Wide Association Study Identifies Susceptibility Variants for Type 2 Diabetes in Han ChineseFuu‐Jen Tsai, Chi-Fan Yang, Ching‐Chu Chen, Lee‐Ming Chuang, Chieh-Hsiang Lu, Chwen‐Tzuei Chang, Tzu-Yuan Wang, Rong-Hsing Chen, Chiung-Fang Shiu, Yi-Min Liu et al. · 2010 · PLoS Genetics
- Efficacy and safety of statin treatment for cardiovascular disease: a network meta-analysis of 170,255 patients from 76 randomized trialsMills, E. J., WU, P., Chong, G., Ghement, I., Singh, S., Akl, E. A., Eyawo, O., Guyatt, G., Berwanger, O., Briel, M. · 2011 · QJM
- Type 2 diabetes as a protein misfolding diseaseAbhisek Mukherjee, Diego Morales‐Scheihing, Peter C. Butler, Claudio A. Soto · 2015 · Trends in Molecular Medicine
- Heterogeneity in Meta-Analyses of Genome-Wide Association InvestigationsJohn P. A. Ioannidis, Nikolaos A. Patsopoulos, Εvangelos Εvangelou · 2007 · PLoS ONE
- Age-Dependent Decline in β-Cell Proliferation Restricts the Capacity of β-Cell Regeneration in MiceTschen, Shuen-Ing, Dhawan, Sangeeta, Gurlo, Tatyana, Bhushan, Anil · 2009 · Diabetes
- Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in miceLemaire, K., Ravier, M. A., Schraenen, A., Creemers, J. W. M., Van de Plas, R., Granvik, M., Van Lommel, L., Waelkens, E., Chimienti, F., Rutter, G. A. et al. · 2009 · Proceedings of the National Academy of Sciences
- Genome-wide scan identifies variation in MLXIPL associated with plasma triglyceridesJaspal Singh Kooner, John Campbell Chambers, Carlos Alberto Aguilar-Salinas, David A. Hinds, Craig L Hyde, Gregory R. Warnes, Francisco J Gómez Pérez, Kelly A. Frazer, Paul Elliott, James Scott et al. · 2008 · Nature Genetics
- Adaptive β-Cell Proliferation Is Severely Restricted With Advanced AgeRankin, Matthew M., Kushner, Jake A. · 2009 · Diabetes
- Healing and Hurting: Molecular Mechanisms, Functions, and Pathologies of Cellular SenescenceAdams, Peter D. · 2009 · Molecular Cell
- New common variants affecting susceptibility to basal cell carcinomaSimon Stacey, Patrick Sulem, Gísli Másson, Sigurjon Axel Gudjonsson, Guðmar Þorleifsson, Margret Jakobsdottir, Ásgeir Sigurðsson, Daniel Fannar Gudbjartsson, Bárður Sigurgeirsson, Kristrún R. Benediktsdóttir et al. · 2009 · Nature Genetics
- STrengthening the REporting of Genetic Association studies (STREGA) – an extension of the STROBE statementJulian Little, Julian P. T. Higgins, John P. A. Ioannidis, David Moher, France Gagnon, Erik B von Elm, Muin J. Khoury, Barbara J. Cohen, George Davey Smith, Jeremy Grimshaw et al. · 2009 · European Journal of Clinical Investigation
- IMPs: an RNA-binding protein family that provides a link between stem cell maintenance in normal development and cancerDegrauwe, Nils, Suvà, Mario-Luca, Janiszewska, Michalina, Riggi, Nicolo, Stamenkovic, Ivan · 2016 · Genes & Development
- Human genetics illuminates the paths to metabolic diseaseStephen O’Rahilly · 2009 · Nature
- The False-positive to False-negative Ratio in Epidemiologic StudiesIoannidis, John P. A., Tarone, Robert, McLaughlin, Joseph K. · 2011 · Epidemiology
- Robust Replication of Genotype-Phenotype Associations across Multiple Diseases in an Electronic Medical RecordMarylyn DeRiggi Ritchie, Joshua C. Denny, Dana C. Crawford, Andrea H. Ramirez, Justin Weiner, Jill M. Pulley, Melissa Basford, Kristin D. Brown-Gentry, Jeffrey R. Balser, Daniel R. Masys et al. · 2010 · The American Journal of Human Genetics
- Diabesity: an overview of a rising epidemicYoussef M K Farag, Mahmoud Gaballa · 2010 · Nephrology Dialysis Transplantation
- Comparison of Two Meta-Analysis Methods: Inverse-Variance-Weighted Average and Weighted Sum of Z-ScoresCue Hyunkyu Lee, Seungho Cook, Ji Sung Lee, Buhm Han · 2016 · Genomics & Informatics
- Genetics and epigenetics of obesityBlanca M. Herrera, Sarah Keildson, Cecilia M. Lindgren · 2011 · Maturitas
- Common Variation in the FTO Gene Alters Diabetes-Related Metabolic Traits to the Extent Expected Given Its Effect on BMIRachel M. Freathy, Nicholas John Timpson, Debbie A. Lawlor, Anneli Pouta, Yoav Ben‐Shlomo, Aimo Ruokonen, Shah B J Ebrahim, Beverley M. Shields, Eleftheria Zeggini, Michael N. Weedon et al. · 2008 · Diabetes
- The ChinaMAP analytics of deep whole genome sequences in 10,588 individualsYanan Cao, Lin Li, Min Xu, Zhimin Feng, Xiaohui Sun, Jieli Lu, Yu Xu, Peina Du, Tiange Wang, Ruying Hu et al. · 2020 · Cell Research
- New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolismThe Meta-Analyses of Glucose- and Insulin-related traits Consortium (MAGIC), Horikoshi, Momoko, Early Growth Genetics (EGG) Consortium, Yaghootkar, Hanieh, Mook-Kanamori, Dennis O, Sovio, Ulla, Taal, H Rob, Hennig, Branwen J, Bradfield, Jonathan P, St Pourcain, Beate et al. · 2013 · Nature Genetics
- DataSHIELD: taking the analysis to the data, not the data to the analysisAmadou Gaye, Yannick Marcon, Julia Isaeva, Philippe Laflamme, Andrew James Turner, Elinor M. Jones, Joel T. Minion, Andrew W Boyd, Chris Newby, Marja-Liisa Nuotio et al. · 2014 · International Journal of Epidemiology
- Genome-Wide AssociationKent D. Taylor, Jill M. Norris, Jerome I. Rotter · 2007 · Diabetes
- The Emerging Genetic Architecture of Type 2 DiabetesAlessandro Doria, Mary‐Elizabeth Patti, C. Ronald Kahn · 2008 · Cell Metabolism
- Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretionNadeeja Wijesekara, Feihan F. Dai, Alexandre B. Hardy, Pejman Raeisi‐Giglou, A. Bhattacharjee, Vasilij Koshkin, Fabrice Chimienti, Herbert Y. Gaisano, Guy A. Rutter, Michael B. Wheeler · 2010 · Diabetologia
- Physical Activity and the Association of Common FTO Gene Variants With Body Mass Index and ObesityRampersaud, Evadnie, Mitchell, Braxton D., Pollin, Toni I., Fu, Mao, Shen, Haiqing, O’Connell, Jeffery R., Ducharme, Julie L., Hines, Scott, Sack, Paul, Naglieri, Rosalie et al. · 2008 · Archives of Internal Medicine
- Gene-Environment Interaction in Genome-Wide Association StudiesCassandra E. Murcray, Juan Pablo Lewinger, W. James Gauderman · 2008 · American Journal of Epidemiology
- Use of diverse electronic medical record systems to identify genetic risk for type 2 diabetes within a genome-wide association studyAbel Kho, M. Geoffrey Hayes, Laura J. Rasmussen‐Torvik, Jennifer A. Pacheco, William K. Thompson, Loren L. Armstrong, Joshua C. Denny, Peggy L. Peissig, Aaron W Miller, Wei‐Qi Wei et al. · 2011 · Journal of the American Medical Informatics Association
- Utility of genetic and non-genetic risk factors in prediction of type 2 diabetes: Whitehall II prospective cohort studyPhilippa J. Talmud, Aroon Dinesh Hingorani, Jackie A. Cooper, Michael Gideon Marmot, Eric John Brunner, Meena Kumari B, Mika Kivimaki B, Steve Eric Humphries · 2010 · BMJ
- Assessing the Combined Impact of 18 Common Genetic Variants of Modest Effect Sizes on Type 2 Diabetes RiskHana Lango Allen, Colin N.A. Palmer, Andrew D. Morris, Eleftheria Zeggini, Andrew Tym Hattersley, Mark I. McCarthy, Timothy M. Frayling, Michael N. Weedon · 2008 · Diabetes
- Replication in Genome-Wide Association StudiesPeter L. Kraft, Eleftheria Zeggini, John P. A. Ioannidis · 2009 · Statistical Science
- Newly identified loci highlight beta cell dysfunction as a key cause of type 2 diabetes: Where are the insulin resistance genes?José C. Florez · 2008 · Diabetologia
- What should the genome-wide significance threshold be? Empirical replication of borderline genetic associationsPanagiotou, Orestis A, Ioannidis, John P A, for the Genome-Wide Significance Project · 2012 · International Journal of Epidemiology
- Genetic programming of liver and pancreas progenitors: lessons for stem-cell differentiationKenneth S. Zaret · 2008 · Nature Reviews Genetics
- Heritability and familiality of type 2 diabetes and related quantitative traits in the Botnia StudyP. Almgren, M. Lehtovirta, B. Isomaa, L. Sarelin, M. Taskinen, V. Lyssenko, T. Tuomi, L. Groop · 2011 · Diabetologia
- Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTOvariants confer a significant riskDharambir K. Sanghera, Lyda Ortega, Shizhong Han, Jairup Singh, Sarju K. Ralhan, Gurpreet Singh Wander, Narinder Kumar Mehra, John Joseph Mulvihill, Robert E. Ferrell, Swapan K. Nath et al. · 2008 · BMC Medical Genetics
- Antidiabetic Effects of IGFBP2, a Leptin-Regulated GeneHedbacker, Kristina, Birsoy, Kıvanç, Wysocki, Robert W., Asilmaz, Esra, Ahima, Rexford S., Farooqi, I. Sadaf, Friedman, Jeffrey M. · 2010 · Cell Metabolism
- Meta-Analysis in Genome-Wide Association StudiesEleftheria Zeggini, John P. A. Ioannidis · 2009 · Pharmacogenomics
- Predicting Type 2 Diabetes Based on Polymorphisms From Genome-Wide Association StudiesMandy van Hoek, Abbas Dehghan, Jacqueline C.M. Witteman, Cornelia M. van Duijn, André Gerardus Uitterlinden, Ben A. Oostra, Albert Hofman D, Eric J.G. Sijbrands, A. Cecile J.W. Janssens · 2008 · Diabetes
- Association ofCDKAL1, IGF2BP2, CDKN2A/B, HHEX,SLC30A8,andKCNJ11With Susceptibility to Type 2 Diabetes in a Japanese PopulationShintaro Omori, Yasushi Tanaka, Atsushi Takahashi, Hiroshi Hirose, Atsunori Kashiwagi, Kohei Kaku, Ryuzo Kawamori, Yusuke Nakamura, Shiro Maeda · 2007 · Diabetes
- Susceptibility loci for intracranial aneurysm in European and Japanese populationsKaya Bilgüvar, Katsuhito Yasuno, Mika Risto Niemela, Ynte Marije Ruigrok, Mikael von und zu Fraunberg, Cornelia M. van Duijn, Leonard H. van den Berg, Shrikant Mane, Christopher E. Mason, Murim Choi et al. · 2008 · Nature Genetics
- Twin studies in autoimmune disease: Genetics, gender and environmentDimitrios Petrou Bogdanos, Daniel S. Smyk, Eirini I. Rigopoulou, Maria G. Mytilinaiou, Michael A. Heneghan, Carlo Francesco Selmi, M. Eric Gershwin · 2011 · Journal of Autoimmunity
- A Genome-Wide Association Study of Gestational Diabetes Mellitus in Korean WomenSoo Heon Kwak, Sung‐Hoon Kim, Young Min Cho, Min Jin Go, Yoon Shin Cho, Sung Hee Choi, Min Kyong Moon, Hye Seung Jung, Hyoung Doo Shin, Hyun Min Kang et al. · 2012 · Diabetes
- Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes LociRicha Saxena, Clara C. Elbers, Yiran Guo, Inga Peter, Tom R. Gaunt, Jessica L. Mega, Matthew Bruce Lanktree, Archana Tare, Berta Almoguera Castillo, Yun R. Li et al. · 2012 · The American Journal of Human Genetics
- The replication of β cells in normal physiology, in disease and for therapyButler, Peter C, Meier, Juris J, Butler, Alexandra E, Bhushan, Anil · 2007 · Nature Clinical Practice Endocrinology & Metabolism
- Adaptations to Climate in Candidate Genes for Common Metabolic DisordersAngela M. Hancock, David Witonsky, ALLAN S. GORDON, Gidon Eshel, Jonathan K. Pritchard, Graham Coop, Anna Di Rienzo · 2008 · PLoS Genetics
- A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4BToshimasa Yamauchi, Kazuo Hara, Shiro Maeda, Kazuki Yasuda, Atsushi Takahashi, Momoko Horikoshi, Masahiro Nakamura, Hayato Fujita, Niels Grarup, Stéphane Cauchi et al. · 2010 · Nature Genetics
- Deficit of tRNALys modification by Cdkal1 causes the development of type 2 diabetes in miceFan‐Yan Wei, Takeo Suzuki, Sayaka Watanabe, 木村聡, Taku Kaitsuka, Atsushi Fujimura, Hideki Matsui, Mohamed Atta, Hiroyuki Michiue, Marc Fontecave et al. · 2011 · Journal of Clinical Investigation
- Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversionKerstin Kirchhoff, Fausto E Machicao, Axel Haupt, Silke Schäfer, Otto Tschritter, Harald Staiger, Norbert Stefan, Hans-Ulrich Häring, Andreas Fritsche · 2008 · Diabetologia
- Association between TCF7L2gene polymorphisms and susceptibility to Type 2 Diabetes Mellitus: a large Human Genome Epidemiology (HuGE) review and meta-analysisTong Yu, Ying Lin, Yuan Zhang, Jiyun Yang, Yawei Zhang, Hengchuan Liu, Ben Zhang · 2009 · BMC Medical Genetics
- Studies of Association of Variants Near the HHEX, CDKN2A/B, and IGF2BP2 Genes With Type 2 Diabetes and Impaired Insulin Release in 10,705 Danish SubjectsNiels Grarup, Chrisian S. Rose, Ehm Astrid Andersson Galijatovic, Gitte Andersen, Arne L. Nielsen, Anders Albrechtsen, Jesper O. Clausen, Signe Sætre Rasmussen, Torben Jørgensen, Annelli Sandbæk et al. · 2007 · Diabetes
- Genotyping Technologies for Genetic ResearchJiannis Ragoussis · 2009 · Annual Review of Genomics and Human Genetics
- Cardiovascular Disease Risk Prediction With and Without Knowledge of Genetic Variation at Chromosome 9p21.3Nina P. Paynter, Daniel I. Chasman, Julie E. Buring, Dov Shiffman, Nancy R. Cook, Paul M. Ridker · 2009 · Annals of Internal Medicine
- Size matters: just how big is BIG?: Quantifying realistic sample size requirements for human genome epidemiologyPaul Robert Burton, Anna Hansell, Isabel Fortier, Teri A. Manolio, Muin J. Khoury, Julian Little, Paul Elliott · 2008 · International Journal of Epidemiology
- Evolutionary Adaptations to Dietary ChangesFrancesca Luca, George H. Perry, Anna Di Rienzo · 2010 · Annual Review of Nutrition
- Integrated Genetic and Epigenetic Analysis Identifies Haplotype-Specific Methylation in the FTO Type 2 Diabetes and Obesity Susceptibility LocusChristopher G. Bell, Sarah Finer, Cecilia M. Lindgren, Gareth A. Wilson, Vardhman K. Rakyan, Andrew Erich Teschendorff, Pelin Akan, Elia Stupka, Thomas A. Down, Inga Prokopenko et al. · 2010 · PLoS ONE
- Comparison of Effect Sizes Associated With Biomarkers Reported in Highly Cited Individual Articles and in Subsequent Meta-analysesJohn P. A. Ioannidis · 2011 · JAMA
- Targeting the pancreatic β-cell to treat diabetesAmedeo Vetere, Amit Choudhary, Sean M. Burns, Bridget K. Wagner · 2014 · Nature Reviews Drug Discovery
- Common Variants of the Novel Type 2 Diabetes GenesCDKAL1andHHEX/IDEAre Associated With Decreased Pancreatic β-Cell FunctionLaura A. Pascoe, Andrea Tura, Sheila K. Patel, Ibrahim M. Ibrahim, Ele Ferrannini, Eleftheria Zeggini, Michael N. Weedon, Andrea Mari, Andrew Tym Hattersley, Mark I. McCarthy et al. · 2007 · Diabetes
- Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA1c levels in human pancreatic isletsYang, B. T., Dayeh, T. A., Kirkpatrick, C. L., Taneera, J., Kumar, R., Groop, L., Wollheim, C. B., Nitert, M. D., Ling, C. · 2011 · Diabetologia
- Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormonesJuan Pablo Maianti, Amanda McFedries, Zachariah H. Foda, Ralph E. Kleiner, Xiu Quan Du, Malcolm A. Leissring, Wei‐Jen Tang, Maureen J. Charron, Markus A. Seeliger, Alan Saghatelian et al. · 2014 · Nature
- Structural basis for autoregulation of the zinc transporter YiiPMin Lu, Jin Ling Chai, Dax Fu · 2009 · Nature Structural & Molecular Biology
- New Insights Into the Circadian Rhythm and Its Related DiseasesXie, Yanling, Tang, Qingming, Chen, Guangjin, Xie, Mengru, Yu, Shaoling, Zhao, Jiajia, Chen, Lili · 2019 · Frontiers in Physiology
- Latent Autoimmune Diabetes in AdultsNaik, Ramachandra G., Brooks-Worrell, Barbara M., Palmer, Jerry P. · 2009 · The Journal of Clinical Endocrinology & Metabolism
- Relationship between β‐cell mass and diabetes onsetAleksey V. Matveyenko, Peter C. Butler · 2008 · Diabetes Obesity and Metabolism
- INK4/ARF transcript expression is associated with chromosome 9p21 variants linked to atherosclerosisLiu, Yan, Sanoff, Hanna K., Cho, Hyunsoon, Burd, Christin E., Torrice, Chad, Mohlke, Karen L., Ibrahim, Joseph G., Thomas, Nancy E., Sharpless, Norman E. · 2009 · PLoS ONE
- The Generation R Study Biobank: a resource for epidemiological studies in children and their parentsVincent W. V. Jaddoe, Rachel Bakker, Cock M. van Duijn, Albert J. van der Heijden, Jan Willem Lindemans, Johan Pieter Mackenbach, Henriëtte A. Moll, Eric A.P. Steegers, Henning W. Tiemeier, André Gerardus Uitterlinden et al. · 2007 · European Journal of Epidemiology
- Current understanding of ZIP and ZnT zinc transporters in human health and diseasesTaiho Kambe, Ayako Hashimoto, Shigeyuki Fujimoto · 2014 · Cellular and Molecular Life Sciences
- Type 2 diabetes-associated genetic variants discovered in the recent genome-wide association studies are related to gestational diabetes mellitus in the Korean populationCho, Y. M., Kim, T. H., Lim, S., Choi, S. H., Shin, H. D., Lee, H. K., Park, K. S., Jang, H. C. · 2009 · Diabetologia
- A Polymorphism Within the G6PC2 Gene Is Associated with Fasting Plasma Glucose LevelsNabila Bouatia‐Naji, Ghislain Rocheleau, Leentje Van Lommel, Katleen Lemaire, Frans C Schuit, Christine Cavalcanti-Proença, Marion Marchand, Anna‐Liisa Hartikainen, Ulla Sovio, Franck De Graeve et al. · 2008 · Science
- Common Variants in <i>CDKAL1</i>, <i>CDKN2A/B</i>, <i>IGF2BP2</i>, <i>SLC30A8</i>, and <i>HHEX/IDE</i> Genes Are Associated With Type 2 Diabetes and Impaired Fasting Glucose in a Chinese Han PopulationWu, Ying, Li, Huaixing, Loos, Ruth J.F., Yu, Zhijie, Ye, Xingwang, Chen, Lihua, Pan, An, Hu, Frank B., Lin, Xu · 2008 · Diabetes
- The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearanceMotoyuki Tamaki, Yoshio Fujitani, Akemi Hara, Toyoyoshi Uchida, Yoshifumi Tamura, Kageumi Takeno, Minako Kawaguchi, Takahiro Watanabe, Takeshi Ogihara, Ayako Fukunaka et al. · 2013 · Journal of Clinical Investigation
- Role of Zinc in Human Islet Amyloid Polypeptide AggregationJeffrey Brender, Kevin L. Hartman, Ravi Prakash Reddy Nanga, Nataliya Popovych, Roberto de la Salud‐Bea, Subramanian Vivekanandan, E. Neil G. Marsh, Ayyalusamy Ramamoorthy · 2010 · Journal of the American Chemical Society
- Genome-Wide Association Studies in Alzheimer DiseaseStephen C. Waring, Roger N. Rosenberg · 2008 · Archives of Neurology
- Gene and Pathway-Based Analysis: Second Wave of Genome-wide Association StudiesGang Peng, Li Luo, Hoicheong Siu, Yun Zhu, Pengfei Hu, Shengjun Hong, Jinying Zhao, Xiaodong Zhou, John D. Reveille, Jin Li et al. · 2008 · European Journal of Human Genetics
- Identification of a Shared Genetic Susceptibility Locus for Coronary Heart Disease and PeriodontitisArne S. Schäefer, Gesa M. Richter, Birte Groessner‐Schreiber, Barbara Noack, Michael Nothnagel, N. E. El Mokhtari, Bruno G. Loos, Søren Vad Jepsen, Stefan Schreiber · 2009 · PLoS Genetics
- Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progressionLee, Yoonjin, Dominy, John E., Choi, Yoon Jong, Jurczak, Michael, Tolliday, Nicola, Camporez, Joao Paulo, Chim, Helen, Lim, Ji-Hong, Ruan, Hai-Bin, Yang, Xiaoyong et al. · 2014 · Nature
- The genetic and neurobiologic compass points toward common signaling dysfunctions in autism spectrum disordersLevitt, Pat, Campbell, Daniel B. · 2009 · Journal of Clinical Investigation
- Confirmation of Multiple Risk Loci and Genetic Impacts by a Genome-Wide Association Study of Type 2 Diabetes in the Japanese PopulationFumihiko Takeuchi, Masakuni Serizawa, Ken Yamamoto, Tomomi Fujisawa, Eitaro Nakashima, Keizo Ohnaka, Hiroshi Ikegami, Takao Sugiyama, Tomohiro Katsuya, Makoto Miyagishi et al. · 2009 · Diabetes
- Genome-wide association studies in type 2 diabetesMark I. McCarthy, Eleftheria Zeggini · 2009 · Current Diabetes Reports
- Joint Effects of Common Genetic Variants on the Risk for Type 2 Diabetes in U.S. Men and Women of European AncestryMarilyn C. Cornelis, Lu Qi, Cuilin Zhang, Peter L. Kraft, JoAnn Elisabeth Manson, Tianxi Cai, David J. Hunter, Frank B. Hu · 2009 · Annals of Internal Medicine
- Common Type 2 Diabetes Risk Gene Variants Associate with Gestational DiabetesJeannet Lauenborg, Niels Grarup, Peter Damm, Knut Borch‐Johnsen, Torben Jørgensen, Oluf Borbye Pedersen, Torben F. Hansen · 2008 · The Journal of Clinical Endocrinology & Metabolism