Identification of host proteins required for HIV infection through a functional genomic screen

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Items 101–200 of 1,000

1. Human cellular restriction factors that target HIV-1 replication
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2. Rab7: roles in membrane trafficking and disease
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3. Direct visualization of HIV-1 replication intermediates shows that capsid and CPSF6 modulate HIV-1 intra-nuclear invasion and integration
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4. HIV Latency: Should We Shock or Lock?
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5. Systems biology of pathogen‐host interaction: Networks of protein‐protein interaction within pathogens and pathogen‐human interactions in the post‐genomic era
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6. Identification of a lipid kinase as a host factor involved in hepatitis C virus RNA replication.
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7. Mapping the LINE1 ORF1 protein interactome reveals associated inhibitors of human retrotransposition
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8. Detecting HIV-1 integration by repetitive-sampling -gag PCR
   Megan K. Liszewski, Jianqing J. Yu, Una O’Doherty · 2009 · Methods
9. Semi-supervised multi-task learning for predicting interactions between HIV-1 and human proteins
   Yanjun Qi, Öznur Taştan, Jaime G. Carbonell, Judith Klein‐Seetharaman, Jason Weston · 2010 · Bioinformatics
10. P Body-Associated Protein Mov10 Inhibits HIV-1 Replication at Multiple Stages
    Ryan C. Burdick, Jessica L. Smith, Chawaree Chaipan, Y. Friew, Jianbo Chen, Narasimhan J. Venkatachari, Krista A. Delviks-Frankenberry, Wei-Shau Hu, V. Pathak · 2010 · Journal of Virology
11. Innate immune modulation by RNA viruses: emerging insights from functional genomics
    Michael G. Katze, Jamie L. Fornek, Robert E. Palermo, Kathie‐Anne Walters, Marcus J. Korth · 2008 · Nature reviews. Immunology
12. Hormonally Active Vitamin D3 (1α,25-Dihydroxycholecalciferol) Triggers Autophagy in Human Macrophages That Inhibits HIV-1 Infection*
    Grant R. Campbell, S. Spector · 2011 · Journal of Biological Chemistry
13. The fight between the teleost fish immune response and aquatic viruses
    Samuel Tekeste Workenhe, Matthew L. Rise, Molly Kibenge, Frederick S.B. Kibenge · 2010 · Molecular Immunology
14. Novel targets for HIV therapy
    Warner C. Greene, Zeger Debyser, Yasuhiro Ikeda, Eric O. Freed, Edward B. Stephens, Wes M. Yonemoto, Robert W. Buckheit, José A. Esté, Tomáš Cihlář · 2008 · Antiviral Research
15. Genome-wide association studies: a new window into immune-mediated diseases
    Ramnik J. Xavier, John David Rioux · 2008 · Nature reviews. Immunology
16. 24 hours in the life of HIV-1 in a T cell line
    Mohammadi, Pejman, Desfarges, Sébastien, Bartha, István, Joos, Beda, Zangger, Nadine, Muñoz, Miguel, Günthard, Huldrych F., Beerenwinkel, Niko, Telenti, Amalio, Ciuffi, Angela · 2013 · PLoS Pathogens
17. Systemic Administration of Combinatorial dsiRNAs via Nanoparticles Efficiently Suppresses HIV-1 Infection in Humanized Mice
    Jiehua Zhou, Charles Preston Neff, Xiaoxuan Liu, Jane Zhang, Haitang Li, David D. Smith, Piotr M. Swiderski, Tawfik Aboellail, Yuanyu Huang, Quan Du et al. · 2011 · Molecular Therapy
18. Microarray Analysis of Lymphatic Tissue Reveals Stage-Specific, Gene Expression Signatures in HIV-1 Infection
    Qing-Sheng Li, A. Smith, T. Schacker, J. Carlis, L. Duan, Cavan Reilly, A. Haase · 2009 · Journal of Immunology
19. Human enterovirus 71 epidemics: what's next?
    C. Yip, S. Lau, Patrick C. Y. Woo, Kwok Y. Yuen · 2013 · Emerging Health Threats Jour
20. RNAi Screening: New Approaches, Understandings and Organisms
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21. Structural basis for nuclear import of splicing factors by human Transportin 3
    G. Maertens, N. Cook, Wei-Feng Wang, S. Hare, Saumya Gupta, Ilker Öztop, Kyeongeun Lee, V. E. Pye, O. Cosnefroy, A. Snijders et al. · 2014 · Proceedings of the National Academy of Sciences of the United States of America
22. TNPO3 protects HIV-1 replication from CPSF6-mediated capsid stabilization in the host cell cytoplasm
    Alberto De Iaco, Federico Andrea Santoni, Anne Vannier, Michel Guipponi, Stylianos E. Antonarakis, Jeremy Luban · 2013 · Retrovirology
23. A whole genome screen for HIV restriction factors
    Li Liu, Nidia M. M. Oliveira, Kelly M. Cheney, Corinna Pade, Hanna S Dreja, Ann-Marie H. Bergin, Viola Borgdorff, David Beach, Cleo L. Bishop, Matthias T. Dittmar et al. · 2011 · Retrovirology
24. Automated microscopy for high-content RNAi screening
    Christian Conrad, Daniel W. Gerlich · 2010 · The Journal of Cell Biology
25. Transport According to GARP: Receiving Retrograde Cargo at the Trans-Golgi Network
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26. Host genes associated with HIV/AIDS: advances in gene discovery
    P. An, C. Winkler · 2010 · Trends in Genetics
27. Viral and Cellular Requirements for the Nuclear Entry of Retroviral Preintegration Nucleoprotein Complexes
    Kenneth A. Matreyek, Alan Engelman · 2013 · Viruses
28. How viruses access the nucleus.
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29. RNA-RNA and RNA-protein interactions in coronavirus replication and transcription
    I. Sola, Pedro A. Mateos-Gómez, F. Almazán, S. Zúñiga, L. Enjuanes · 2011 · RNA Biology
30. Short Communication: Cataloguing the HIV Type 1 Human Protein Interaction Network
    R. Ptak, W. Fu, Brigitte E. Sanders-Beer, Jonathan E. Dickerson, J. Pinney, D. Robertson, M. Rozanov, K. Katz, D. Maglott, K. Pruitt et al. · 2008 · AIDS Research and Human Retroviruses
31. Enabling a systems biology approach to immunology: focus on innate immunity
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32. Novel innate immune functions of the whey acidic protein family.
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33. Long noncoding RNA MALAT1 releases epigenetic silencing of HIV-1 replication by displacing the polycomb repressive complex 2 from binding to the LTR promoter
    Di Qu, Wei-Wei Sun, Li Li, Li Ma, Li Sun, Xia Jin, Tai-Sheng Li, W. Hou, Jian-Hua Wang · 2019 · Nucleic Acids Research
34. Dynamic regulation of HIV-1 mRNA populations analyzed by single-molecule enrichment and long-read sequencing
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35. Cell Entry of Enveloped Viruses
    François‐Loïc Cosset, Dimitri Lavillette · 2011 · Advances in genetics
36. Inositol pyrophosphate mediated pyrophosphorylation of AP3B1 regulates HIV-1 Gag release
    Cristina Azevedo, Adam Burton, Ezequiel Ruíz-Mateos, Mark Marsh, Adolfo Saiardi · 2009 · Proceedings of the National Academy of Sciences
37. Vigilance and Validation: Keys to Success in RNAi Screening
    Frederic D. Sigoillot, Randall W. King · 2010 · ACS Chemical Biology
38. Differential Role of Autophagy in CD4 T Cells and Macrophages during X4 and R5 HIV-1 Infection
    Lucile Espert, M. Varbanov, V. Robert-Hebmann, S. Sagnier, I. Robbins, Françoise Sanchez, V. Lafont, Martine Biard-Piechaczyk · 2009 · PLoS ONE
39. Viral manipulation of DNA repair and cell cycle checkpoints
    Mira S. Chaurushiya, Matthew D. Weitzman · 2009 · DNA repair
40. Current Scenario of HIV/AIDS, Treatment Options, and Major Challenges with Compliance to Antiretroviral Therapy
    A. Bhatti, Muhammad Usman, V. Kandi · 2016 · Cureus
41. Structural principles within the human-virus protein-protein interaction network
    Eric A. Franzosa, Yu Xia · 2011 · Proceedings of the National Academy of Sciences
42. Role of Nef in primate lentiviral immunopathogenesis
    Frank Kirchhoff, Michael Schindler, Anke Specht, N. Arhel, Jan Münch · 2008 · Cellular and Molecular Life Sciences
43. A virus-packageable CRISPR screen identifies host factors mediating interferon inhibition of HIV
    Molly OhAinle, Louisa Helms, Jolien Vermeíre, Ferdinand Roesch, Daryl G. Humes, Ryan Basom, Jeffrey J. Delrow, Julie M. Overbaugh, Michael Emerman · 2018 · eLife
44. DDX3 DEAD-Box RNA Helicase Inhibits Hepatitis B Virus Reverse Transcription by Incorporation into Nucleocapsids
    Haifeng Wang, Seahee Kim, W. Ryu · 2009 · Journal of Virology
45. Host Cell Autophagy Is Induced by Toxoplasma gondii and Contributes to Parasite Growth*
    Yu-Bao Wang, L. Weiss, A. Orlofsky · 2009 · Journal of Biological Chemistry
46. Systematic identification of synergistic drug pairs targeting HIV
    Xu Tan, Long Hu, Lovelace J. Luquette, Geng Gao, Yifang Liu, Hongjing Qu, Ruibin Xi, Zhi John Lu, Peter J. Park, Stephen Joseph Elledge · 2012 · Nature Biotechnology
47. Molecular mechanisms of retroviral integration site selection
    M. Kvaratskhelia, Amit Sharma, Ross C. Larue, Erik Serrao, A. Engelman · 2014 · Nucleic Acids Research
48. The Host Proteins Transportin SR2/TNPO3 and Cyclophilin A Exert Opposing Effects on HIV-1 Uncoating
    Vaibhav B. Shah, Jiong Shi, David Richard Hout, Ilker Öztop, Lavanya Krishnan, Jinwoo Ahn, Matthew Stephen Shotwell, Alan Engelman, Christopher Aiken · 2012 · Journal of Virology
49. Human Pathogens and the Host Cell SUMOylation System
    P. Wimmer, S. Schreiner, T. Dobner · 2011 · Journal of Virology
50. Host proteins involved in HIV infection: New therapeutic targets
    Nathalie Jane Arhel, Frank Kirchhoff · 2009 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
51. HIV‐exposed seronegative commercial sex workers show a quiescent phenotype in the CD4+ T cell compartment and reduced expression of HIV‐dependent host factors.
    P. J. McLaren, T. Ball, C. Wachihi, W. Jaoko, D. J. Kelvin, A. Danesh, Joshua Kimani, Francis A. Plummer, K. Fowke · 2010 · Journal of Infectious Diseases
52. Transportin 3 promotes a nuclear maturation step required for efficient HIV-1 integration
    Zhou, Lihong, Sokolskaja, Elena, Jolly, Clare, James, William, Cowley, Sally A., Fassati, Ariberto · 2011 · PLoS Pathogens
53. Chromatin organization at the nuclear pore favours HIV replication
    Mickaël Lelek, Nicoletta Casartelli, Danilo Pellin, Ermanno Rizzi, Philippe Souque, Marco Severgnini, Clelia Di Serio, Thomas Fricke, Felipe Diaz‐Griffero, Christophe Zimmer et al. · 2015 · Nature Communications
54. Host-Directed Drug Targeting of Factors Hijacked by Pathogens
    Anita Schwegmann, Frank Brombacher · 2008 · Science Signaling
55. Early cytoplasmic uncoating is associated with infectivity of HIV-1
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56. Functional In Vivo Delivery of Multiplexed Anti-HIV-1 siRNAs via a Chemically Synthesized Aptamer With a Sticky Bridge
    Jiehua Zhou, Charles Preston Neff, Piotr M. Swiderski, Haitang Li, David D. Smith, Tawfik Aboellail, Leila Remling‐Mulder, Ramesh Akkina, John J. Rossi · 2012 · Molecular Therapy
57. Integrase Interacts with Nucleoporin NUP153 To Mediate the Nuclear Import of Human Immunodeficiency Virus Type 1
    Cora L. Woodward, Sarin Prakobwanakit, Sherly Mosessian, S A Chow · 2009 · Journal of Virology
58. Autophagy, antiviral immunity, and viral countermeasures
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59. Host Cell Interactome of HIV-1 Rev Includes RNA Helicases Involved in Multiple Facets of Virus Production*
    Souad Naji, G. Ambrus, Peter Cimermancic, Jason R. Reyes, Jeffrey R. Johnson, Rebecca Filbrandt, M. D. Huber, P. Vesely, N. Krogan, J. Yates et al. · 2011 · Molecular & Cellular Proteomics
60. The Human Immunodeficiency Virus Type 2 Vpx Protein Usurps the CUL4A-DDB1 ^DCAF1 Ubiquitin Ligase To Overcome a Postentry Block in Macrophage Infection
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61. Toll-Like Receptor 8 Ligands Activate a Vitamin D Mediated Autophagic Response that Inhibits Human Immunodeficiency Virus Type 1
    Grant R. Campbell, S. Spector · 2012 · PLoS Pathogens
62. Capsid-Dependent Host Factors in HIV-1 Infection
    Masahiro Yamashita, Alan Engelman · 2017 · Trends in Microbiology
63. MicroRNAs and HIV-1 Infection: Antiviral Activities and Beyond
    Gokul Swaminathan, Sonia Navas, Julio Martín‐García · 2013 · Journal of Molecular Biology
64. Hiv-1 Assembly at the Plasma Membrane: Gag Trafficking and Localization
    Akira Ono · 2009 · Future Virology
65. Virus strategies for passing the nuclear envelope barrier
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66. Knockdown Screens to Knockout HIV-1
    Stephen P. Goff · 2008 · Cell
67. CRISPR–Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV–host factor interactions
    Judd F. Hultquist, Joseph B Hiatt, Kathrin Schumann, Michael McGregor, Theodore L. Roth, Paige Haas, Jennifer A. Doudna, Alexander Marson, Nevan J. Krogan · 2018 · Nature Protocols
68. HIV-1 capsid undergoes coupled binding and isomerization by the nuclear pore protein NUP358
    Katsiaryna Bichel, Amanda J. Price, Torsten Schaller, Greg J. Towers, Stefan M.V. Freund, Leo C. James · 2013 · Retrovirology
69. Identification of Host-Dependent Survival Factors for Intracellular Mycobacterium tuberculosis through an siRNA Screen
    Shilpi Jayaswal, Mohammad Azhar Kamal, Raina Dua, Shashank Gupta, Tanmay Majumdar, Gobardhan Das, Dhiraj Kumar, Kanury V. S. Rao · 2010 · PLoS Pathogens
70. Curing a viral infection by targeting the host: The example of cyclophilin inhibitors
    Kai Wei Lin, Philippe A. Gallay · 2013 · Antiviral Research
71. The ESCRT-0 Component HRS is Required for HIV-1 Vpu-Mediated BST-2/Tetherin Down-Regulation
    Katy Janvier, A. Pelchen-Matthews, J. Renaud, M. Caillet, M. Marsh, C. Berlioz-Torrent · 2011 · PLoS Pathogens
72. Host hindrance to HIV-1 replication in monocytes and macrophages
    Anna Bergamaschi, Gianfranco Pancino · 2010 · Retrovirology
73. Nuclear pore heterogeneity influences HIV-1 infection and the antiviral activity of MX2
    Melissa Kane, Stephanie V. Rebensburg, Matthew A. Takata, Trinity M. Zang, Masahiro Yamashita, Mamuka Kvaratskhelia, Paul D. Bieniasz · 2018 · eLife
74. Nuclear landscape of HIV-1 infection and integration
    Marina Lušić, Robert F. Siliciano · 2016 · Nature Reviews Microbiology
75. A review on computational systems biology of pathogen–host interactions
    Saliha DurmuÅŸ, Tunahan Çakır, Arzucan Özgür, Reinhard Guthke · 2015 · Frontiers in Microbiology
76. Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression
    Jennifer A. Smith, E. White, M. Sowa, Maria L. C. Powell, Matthias Ottinger, J. Harper, P. Howley · 2010 · Proceedings of the National Academy of Sciences of the United States of America
77. KIF5B and Nup358 Cooperatively Mediate the Nuclear Import of HIV-1 during Infection
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78. Activity of Hexokinase Is Increased by Its Interaction with Hepatitis C Virus Protein NS5A
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79. A Role for microRNA-155 Modulation in the Anti-HIV-1 Effects of Toll-Like Receptor 3 Stimulation in Macrophages
    Gokul Swaminathan, Fiorella Rossi, Luz‐Jeannette Sierra, Archana Anshuman Gupta, Sonia Navas, Julio Martín‐García · 2012 · PLoS Pathogens
80. HIV-1 exploits importin 7 to maximize nuclear import of its DNA genome
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81. Nup153 unlocks the nuclear pore complex for HIV-1 nuclear translocation in nondividing cells
    Buffone, Cindy, Martinez-Lopez, Alicia, Fricke, Thomas, Opp, Silvana, Severgnini, Marco, Cifola, Ingrid, Petiti, Luca, Frabetti, Stella, Skorupka, Katarzyna, Zadrozny, Kaneil K. et al. · 2018 · Journal of Virology
82. Quantitative Phosphoproteomics Reveals Extensive Cellular Reprogramming During HIV-1 Entry
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83. Discovery of Novel Small-Molecule HIV-1 Replication Inhibitors That Stabilize Capsid Complexes
    Louie Lamorte, Steve Titolo, Christopher T. Lemke, Nathalie Goudreau, Jean-François Mercier, Elizabeth Wardrop, Vaibhav B. Shah, Uta K. von Schwedler, Charles Langelier, Soma S. R. Banik et al. · 2013 · Antimicrobial Agents and Chemotherapy
84. Systematic Identification of Barriers to Human iPSC Generation
    Han Qin, Aaron A. Diaz, Laure Blouin, Robert Jan Lebbink, Weronika Patena, Priscilia Tanbun, Emily M LeProust, Michael T. McManus, Jun S. Song, Miguel Ramalho‐Santos · 2014 · Cell
85. Discovering pathways by orienting edges in protein interaction networks
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86. Human genome-wide RNAi screen reveals a role for nuclear pore proteins in poxvirus morphogenesis
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87. RNAi screening reveals requirement for host cell secretory pathway in infection by diverse families of negative-strand RNA viruses
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88. Systems vaccinology: learning to compute the behavior of vaccine induced immunity
    Helder Imoto Nakaya, Shuzhao Li, Bali Pulendran · 2011 · WIREs Systems Biology and Medicine
89. Host restriction factors in retroviral infection: promises in virus-host interaction
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90. Perturbation of Host Nuclear Membrane Component RanBP2 Impairs the Nuclear Import of Human Immunodeficiency Virus -1 Preintegration Complex (DNA)
    Ruonan Zhang, Rajeev Mehla, Ashok Chauhan · 2010 · PLoS ONE
91. Yeast Barcoders: a chemogenomic application of a universal donor-strain collection carrying bar-code identifiers
    Zhun Yan, Michael Costanzo, Lawrence E. Heisler, Jadine Paw, Fiona Kaper, Brenda Andrews, Charles M. Boone, Guri N. Giaever, Corey Nislow · 2008 · Nature Methods
92. Importin α3 Interacts with HIV-1 Integrase and Contributes to HIV-1 Nuclear Import and Replication
    Zhujun Ao, Kallesh Danappa Jayappa, Binchen Wang, Yingfeng Zheng, Sam K. P. Kung, E. Rassart, R. Depping, Matthias Kohler, É. Cohen, Xiao-Jian Yao · 2010 · Journal of Virology
93. The HIV-1-containing macrophage compartment: a perfect cellular niche?
    Joshua H. Y. Tan, Q. Sattentau · 2013 · Trends in Microbiology
94. Inhibition of HIV-1 infection by TNPO3 depletion is determined by capsid and detectable after viral cDNA enters the nucleus
    Alberto De Iaco, Jeremy Luban · 2011 · Retrovirology
95. Bicaudal D2 facilitates the cytoplasmic trafficking and nuclear import of HIV-1 genomes during infection
    A. Dharan, S. Opp, Omar Abdelrahim, Sevnur Komurlu Keceli, S. Imam, Felipe Diaz-Griffero, E. Campbell · 2017 · Proceedings of the National Academy of Sciences of the United States of America
96. Multiple roles of the capsid protein in the early steps of HIV-1 infection
    Ariberto Fassati · 2012 · Virus Research
97. Elite Controllers with Low to Absent Effector CD8+ T Cell Responses Maintain Highly Functional, Broadly Directed Central Memory Responses
    Z. Ndhlovu, J. Proudfoot, K. Cesa, D. Alvino, A. McMullen, Seanna M. Vine, Eleni Stampouloglou, A. Piechocka-Trocha, B. Walker, F. Pereyra · 2012 · Journal of Virology
98. Supervised learning and prediction of physical interactions between human and HIV proteins
    Matthew D. Dyer, T. M. Murali, Bruno Sobral · 2011 · Infection Genetics and Evolution
99. Constitutive resistance to viral infection in human CD141 + dendritic cells
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100. The SET Complex Acts as a Barrier to Autointegration of HIV-1
     Nan Yan, Peter Cherepanov, Janet E. Daigle, Alan Engelman, Judy Lieberman · 2009 · PLoS Pathogens