Cited by 494interferon and immune responsesImmune Response and InflammationImmune responses and vaccinations

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A Family of IFN-γ–Inducible 65-kD GTPases Protects Against Bacterial Infection

Kim, Bae-Hoon, Shenoy, Avinash R., Kumar, Pradeep, Das, Rituparna, Tiwari, Sangeeta, MacMicking, John D.·2011·Science

DOI 10.1126/science.1201711

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Abstract

Guanylate-binding proteins coordinately regulate oxidative and autophagic responses to intracellular bacteria.

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Crossref · 10.1126/science.1201711

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Shenoy A. R., et al.., Immunobiology 8, 771 (2007).
Myers J. T., Tsang A. W., Swanson J. A., J. Leukoc. Biol. 171, 5447 (2003).

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Authors: Kim, B.-H., Shenoy, A. R., Kumar, P., Das, R., Tiwari, S., & MacMicking, J. D.
Affiliations: Yale University (US)
Corresponding author: MacMicking, John D.
ORCID: Kim, Bae-Hoon
Shenoy, Avinash R.
Kumar, Pradeep
Das, Rituparna
Tiwari, Sangeeta
MacMicking, John D.
Venue: Science
Publisher: American Association for the Advancement of Science (AAAS)
Published: 2011-05-06
Volume: 332
Issue: 6030
Pages: 717-721
ISSN: 0036-8075 (ISSN-L)
1095-9203
DOI: 10.1126/science.1201711
OpenAlex: W2087470992
Cited by: 494
References: 22
Citations by year: 2026: 22 · 2025: 31 · 2024: 24 · 2023: 30 · 2022: 40 · 2021: 28 · 2020: 26 · 2019: 25 · 2018: 29 · 2017: 42 · 2016: 29 · 2015: 30 · 2014: 27 · 2013: 51 · 2012: 52
FWCI: 19.58
Type: journal article
Language: en
Open access: closed
Licence: www.sciencemag.org/site/feature/contribinfo/prep/license.xhtml (vor)
Locations: Science (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute of Allergy and Infectious Diseases (R01 AI068041-01A1)
Topics: Life Sciences › Immunology and Microbiology › Immunology › interferon and immune responses
Life Sciences › Immunology and Microbiology › Immunology › Immune Response and Inflammation
Life Sciences › Immunology and Microbiology › Immunology › Immune responses and vaccinations
Keywords: interferon-gamma, guanylate-binding proteins, GTPase, GBP1, cell-autonomous immunity, intracellular bacterial infection, mycobacterial infection, macrophages, antimicrobial peptides, autophagy, vesicle trafficking, oxidative killing, host defense genes
MeSH terms: Animals, Autophagy, Cell Line, Humans, Immunity, Innate, Interferon-gamma, Listeriosis, Listeria monocytogenes, Lysosomes, Macrophages, Mycobacterium bovis, Oxidation-Reduction, Peptides, Phagocytosis, Phagosomes, Tuberculosis, GTP-Binding Proteins, NADPH Oxidases, RNA Interference, Mice

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A Family of IFN-γ–Inducible 65-kD GTPases Protects Against Bacterial Infection

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