Cited by 240T-cell and Retrovirus StudiesXenotransplantation and immune responseViral-associated cancers and disorders

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Recombinant Origin of the Retrovirus XMRV

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Paprotka, Tobias, Delviks-Frankenberry, Krista A., Cingöz, Oya, Martinez, Anthony, Kung, Hsing-Jien, Tepper, Clifford G., Hu, Wei-Shau, Fivash, Matthew J., Coffin, John M., Pathak, Vinay K.·2011·Science

DOI 10.1126/science.1205292PMC PMC3278917

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Abstract

Analysis of the origin of XMRV suggests that links between the virus and human disease are due to laboratory contamination.

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4 retracted

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Urisman, A., Molinaro, R. J., Fischer, N., Plummer, S. J., Casey, G., Klein, E. A., Malathi, K., Magi-Galluzzi, C., Tubbs, R. R., Ganem, D., et al. (2006) · PLoS Pathogens · doi:10.1371/journal.ppat.0020025 · Cited by 577
Retracted
Detection of an Infectious Retrovirus, XMRV, in Blood Cells of Patients with Chronic Fatigue Syndrome
Lombardi, V. C., Ruscetti, F. W., Das Gupta, J., Pfost, M. A., Hagen, K. S., Peterson, D. L., Ruscetti, S. K., Bagni, R. K., Petrow-Sadowski, C., Gold, B., et al. (2009) · Science · doi:10.1126/science.1179052 · Cited by 538
Retracted
RETRACTED: XMRV is present in malignant prostatic epithelium and is associated with prostate cancer, especially high-grade tumors
Schlaberg, R., Choe, D. J., Brown, K. R., Thaker, H. M., & Singh, I. R. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0906922106 · Cited by 275
Retracted
RETRACTED: Detection of MLV-related virus gene sequences in blood of patients with chronic fatigue syndrome and healthy blood donors
Lo, S., Pripuzova, N. S., Li, B., Komaroff, A. L., Hung, G.-C., Wang, R., & Alter, H. J. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1006901107 · Cited by 194
Retracted
Molecular characterization of human prostate carcinoma cell lines
van Bokhoven, A., Varella‐Garcia, M., Korch, C. T., Johannes, W. U., Smith, E. E., Miller, H. L., Nordeen, S. K., Miller, G. J., & Lucia, M. S. (2003) · The Prostate · doi:10.1002/pros.10290 · Cited by 635
A new human prostate carcinoma cell line, 22Rv1
Sramkoski, R., Pretlow, T. G. I., Giaconia, J. M., Pretlow, T. P., Schwartz, S., Sy, M., Marengo, S. R., Rhim, J. S., Zhang, D.-E., & Jacobberger, J. (1999) · In vitro Cellular & Developmental Biology-Animal · doi:10.1007/s11626-999-0115-4 · Cited by 625
Untitled work
(2001) · PubMed · Cited by 500
Broad spectrum of in vivo forward mutations, hypermutations, and mutational hotspots in a retroviral shuttle vector after a single replication cycle: substitutions, frameshifts, and hypermutations.
Pathak, V. K., & Temin, H. M. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.16.6019 · Cited by 280
Self-citation
Untitled work
(1996) · PubMed · Cited by 238
Self-citation
Xenografts of Primary Human Prostatic Carcinoma
Pretlow, T. G., Wolman, S. R., Micale, M. A., Pelley, R. J., Kursh, E. D., Resnick, M. I., Bodner, D. R., Jacobberger, J. W., Delmoro, C. M., Giaconia, J. M., et al. (1993) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/85.5.394 · Cited by 154

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Authors: Paprotka, T., Delviks-Frankenberry, K. A., Cingöz, O., Martinez, A., Kung, H.-J., Tepper, C. G., Hu, W.-S., Fivash, M. J., Coffin, J. M., & Pathak, V. K.
Affiliations: Frederick National Laboratory for Cancer Research (US)
Viral Mutation Section, HIV Drug Resistance Program, National Cancer Institute at Frederick, Frederick, MD 21702, USA.
Tufts University (US)
University of California, Davis (US)
National Cancer Institute (US)
Corresponding author: Pathak, Vinay K.
ORCID: Cingöz, Oya
Martinez, Anthony
Tepper, Clifford G.
Hu, Wei-Shau
Coffin, John M.
Pathak, Vinay K.
Venue: Science
Publisher: American Association for the Advancement of Science (AAAS)
Published: 2011-07
Volume: 333
Issue: 6038
Pages: 97-101
ISSN: 0036-8075 (ISSN-L)
1095-9203
DOI: 10.1126/science.1205292
PMC: PMC3278917
OpenAlex: W2067387759
Cited by: 240
References: 25
Citations by year: 2026: 3 · 2024: 2 · 2023: 2 · 2022: 1 · 2021: 7 · 2020: 6 · 2019: 5 · 2018: 5 · 2017: 12 · 2016: 14 · 2015: 12 · 2014: 16 · 2013: 26 · 2012: 68
FWCI: 23.97
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Science (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health
National Cancer Institute (R37CA089441, R01CA150197, ZIABC011339, P30CA093373)
Topics: Life Sciences › Immunology and Microbiology › Immunology › T-cell and Retrovirus Studies
Health Sciences › Medicine › Surgery › Xenotransplantation and immune response
Health Sciences › Medicine › Oncology › Viral-associated cancers and disorders
Keywords: XMRV, viral recombination, provirus, prostate cancer cell lines, tumor xenografts, chronic fatigue syndrome, sample contamination
MeSH terms: Animals, DNA, Viral, Humans, Male, Mice, Nude, Neoplasm Transplantation, Prostatic Neoplasms, Proviruses, Recombination, Genetic, Transplantation, Heterologous, Fatigue Syndrome, Chronic, Genes, gag, Genes, env, Polymerase Chain Reaction, Gammaretrovirus, Endogenous Retroviruses, Cell Line, Tumor, Mice, Xenotropic murine leukemia virus-related virus, DNA Contamination

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