Coffin, John M.

Specific HIV integration sites are linked to clonal expansion and persistence of infected cells

Maldarelli, F., Wu, X., Su, L., Simonetti, F. R., Shao, W., Hill, S., Spindler, J., Ferris, A. L., Mellors, J. W., Kearney, M. F., et al. (2014) · Science

HIV Research and TreatmentVirus-based gene therapy research

Cited by 849

New Real-Time Reverse Transcriptase-Initiated PCR Assay with Single-Copy Sensitivity for Human Immunodeficiency Virus Type 1 RNA in Plasma

Palmer, S., Wiegand, A. P., Maldarelli, F., Bazmi, H., Mican, J. M., Polis, M., Dewar, R. L., Planta, A., Liu, S., Metcalf, J. A., et al. (2003) · Journal of Clinical Microbiology

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 604

Multiple, Linked Human Immunodeficiency Virus Type 1 Drug Resistance Mutations in Treatment-Experienced Patients Are Missed by Standard Genotype Analysis

Palmer, S., Kearney, M., Maldarelli, F., Halvas, E. K., Bixby, C. J., Bazmi, H., Rock, D., Falloon, J., Davey, R. T., Dewar, R. L., et al. (2005) · Journal of Clinical Microbiology

HIV/AIDS drug development and treatmentHIV Research and Treatment

Cited by 506

Effects of Retroviruses on Host Genome Function

Jern, P., & Coffin, J. M. (2008) · Annual Review of Genetics

Chromosomal and Genetic VariationsEvolution and Genetic Dynamics

Cited by 499

Identification, characterization, and comparative genomic distribution of the HERV-K (HML-2) group of human endogenous retroviruses

Subramanian, R. P., Wildschutte, J. H., Russo, C., & Coffin, J. M. (2011) · Retrovirology

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 439

Clonally expanded CD4 + T cells can produce infectious HIV-1 in vivo

Simonetti, F. R., Sobolewski, M. D., Fyne, E., Shao, W., Spindler, J., Hattori, J., Anderson, E. M., Watters, S. A., Hill, S., Wu, X., et al. (2016) · Proceedings of the National Academy of Sciences

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 372

Recombinant Origin of the Retrovirus XMRV

Paprotka, T., Delviks-Frankenberry, K. A., Cingöz, O., Martinez, A., Kung, H.-J., Tepper, C. G., Hu, W.-S., Fivash, M. J., Coffin, J. M., & Pathak, V. K. (2011) · Science

T-cell and Retrovirus StudiesXenotransplantation and immune response

Cited by 240

Constructing primate phylogenies from ancient retrovirus sequences

Johnson, W. E., & Coffin, J. M. (1999) · Proceedings of the National Academy of Sciences

Chromosomal and Genetic VariationsEvolution and Paleontology Studies

Cited by 199

A linkage map of endogenous murine leukemia proviruses.

Frankel, W. N., Stoye, J. P., Taylor, B. A., & Coffin, J. M. (1990) · Genetics

Genetic Mapping and Diversity in Plants and AnimalsChromosomal and Genetic Variations

Cited by 197

Transition between stochastic evolution and deterministic evolution in the presence of selection: general theory and application to virology

Rouzine, I. M., Rodrigo, A., & Coffin, J. M. (2001) · Microbiology and Molecular Biology Reviews

Evolution and Genetic DynamicsMathematical and Theoretical Epidemiology and Ecology Models

Cited by 173

Single-cell analysis of HIV-1 transcriptional activity reveals expression of proviruses in expanded clones during ART

Wiegand, A., Spindler, J., Hong, F. F., Shao, W., Cyktor, J. C., Cillo, A. R., Halvas, E. K., Coffin, J. M., Mellors, J. W., & Kearney, M. F. (2017) · Proceedings of the National Academy of Sciences

HIV Research and TreatmentVirus-based gene therapy research

Cited by 165

Symmetrical base preferences surrounding HIV-1, avian sarcoma/leukosis virus, and murine leukemia virus integration sites

Holman, A. G., & Coffin, J. M. (2005) · Proceedings of the National Academy of Sciences

HIV Research and TreatmentVirus-based gene therapy research

Cited by 164

The Nucleotide Sequence Complexity of Avian Tumor Virus RNA

Billeter, M. A., Parsons, J. T., & Coffin, J. M. (1974) · Proceedings of the National Academy of Sciences

T-cell and Retrovirus StudiesRNA and protein synthesis mechanisms

Cited by 147

Distribution of targets for avian retrovirus DNA integration in vivo

Withers-Ward, E. S., Kitamura, Y., Barnes, J. P., & Coffin, J. M. (1994) · Genes & Development

T-cell and Retrovirus StudiesVirus-based gene therapy research

Cited by 125

Human Endogenous Retroviral Elements as Indicators of Ectopic Recombination Events in the Primate Genome

Hughes, J. F., & Coffin, J. M. (2005) · Genetics

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 104

Relationship of avian retrovirus DNA synthesis to integration in vitro.

Lee, Y. M., & Coffin, J. M. (1991) · Molecular and Cellular Biology

T-cell and Retrovirus StudiesVirus-based gene therapy research

Cited by 77

The Discovery of Reverse Transcriptase

Coffin, J. M., & Fan, H. (2016) · Annual Review of Virology

History of Science and MedicinePhilosophy of Biology and Scientific Explanation

Cited by 71

ICTV Virus Taxonomy Profile: Retroviridae 2021: This article is part of the ICTV Virus Taxonomy Profiles collection.

Coffin, J., Blomberg, J., Fan, H., Gifford, R., Hatziioannou, T., Lindemann, D., Mayer, J., Stoye, J., Tristem, M., Johnson, W., et al. (2021) · Journal of General Virology

T-cell and Retrovirus StudiesInfectious Diseases and Mycology

Cited by 67

Efficient autointegration of avian retrovirus DNA in vitro

Lee, Y. M., & Coffin, J. M. (1990) · Journal of Virology

Virus-based gene therapy researchT-cell and Retrovirus Studies

Cited by 59

Gorillas have been infected with the HERV-K (HML-2) endogenous retrovirus much more recently than humans and chimpanzees

Holloway, J. R., Williams, Z. H., Freeman, M. M., Bulow, U., & Coffin, J. M. (2019) · Proceedings of the National Academy of Sciences

Chromosomal and Genetic VariationsEvolution and Genetic Dynamics

Cited by 40

Polyadenylation at correct sites in genome RNA is not required for retrovirus replication or genome encapsidation

Swain, A., & Coffin, J. M. (1989) · Journal of Virology

RNA Research and SplicingT-cell and Retrovirus Studies

Cited by 38

Oncogenicity of DNA in vivo: Tumor induction with expression plasmids for activated H-ras and c-myc

Sheng, L., Cai, F., Zhu, Y., Pal, A., Athanasiou, M., Orrison, B., Blair, D. G., Hughes, S. H., Coffin, J. M., Lewis, A. M., et al. (2008) · Biologicals

Carcinogens and Genotoxicity AssessmentImmunotherapy and Immune Responses

Cited by 35

Tumors Induced in Mice by Direct Inoculation of Plasmid DNA Expressing Both Activated H-ras and c-myc

Sheng-Fowler, L., Cai, F., Fu, H., Zhu, Y., Orrison, B., Foseh, G., Blair, D. G., Hughes, S. H., Coffin, J. M., Lewis Jr, A. M., et al. (2010) · International Journal of Biological Sciences

Carcinogens and Genotoxicity AssessmentImmunotherapy and Immune Responses

Cited by 11

A Mouse Strain Defective in Both T Cells and NK Cells Has Enhanced Sensitivity to Tumor Induction by Plasmid DNA Expressing Both Activated H-Ras and c-Myc

Sheng-Fowler, L., Tu, W., Fu, H., Murata, H., Lanning, L., Foseh, G., Macauley, J., Blair, D., Hughes, S. H., Coffin, J. M., et al. (2014) · PLoS ONE

Carcinogens and Genotoxicity AssessmentImmunotherapy and Immune Responses

Cited by 7