The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
Interfollicular Epidermal Stem Cells Self-Renew via Autocrine Wnt Signaling
Open accessAbstract
Epithelial Stem Cells: Much remains to be known about how epithelial stem cells are generated and maintained. Lim et al. (p. 1226 ; see the Perspective by Frede and Jones ) describe a mechanism of stem cell maintenance where epidermal stem cells generate their own self-renewing Wnt signals rather than being controlled by adjacent “niche” signals. These stem cells also express secreted Wnt inhibitors that become localized to more differentiated progeny cells. These autocrine Wnt signals and paracrine long-range Wnt inhibitors may balance stem cell self-renewal and differentiation.
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Cited by
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
Nusse, R., & Clevers, H. (2017) · Cell · doi:10.1016/j.cell.2017.05.016 · Cited by 4,342
Self-citationAn integral program for tissue renewal and regeneration: Wnt signaling and stem cell control
Clevers, H., Loh, K. M., & Nusse, R. (2014) · Science · doi:10.1126/science.1248012 · Cited by 1,364
Self-citationWnt signaling in development and tissue homeostasis
Steinhart, Z., & Angers, S. (2018) · Development · doi:10.1242/dev.146589 · Cited by 821
Self-renewing diploid Axin2+ cells fuel homeostatic renewal of the liver
Wang, B., Zhao, L., Fish, M., Logan, C. Y., & Nusse, R. (2015) · Nature · doi:10.1038/nature14863 · Cited by 674
Self-citationPlasticity of epithelial stem cells in tissue regeneration
Blanpain, C., & Fuchs, E. (2014) · Science · doi:10.1126/science.1242281 · Cited by 589
Metadata
- Authors
- Lim, X., Tan, S. H., Koh, W. L. C., Chau, R. M. W., Yan, K. S., Kuo, C. J., van Amerongen, R., Klein, A. M., & Nusse, R.
- Venue
- Science
- Published
- 2013-12-06
- Volume
- 342
- Issue
- 6163
- Pages
- 1226-1230
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2084686942
- Cited by
- 347
- References
- 37
- FWCI
- 39.50
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Interfollicular Epidermal Stem Cells Self-Renew via Autocrine Wnt Signaling. https://app.cochat.ai/papers/10.1126/science.1239730
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- Lim, X., Tan, S. H., Koh, W. L. C., Chau, R. M. W., Yan, K. S., Kuo, C. J., van Amerongen, R., Klein, A. M., & Nusse, R. (2013). Interfollicular Epidermal Stem Cells Self-Renew via Autocrine Wnt Signaling. Science. https://doi.org/10.1126/science.1239730
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
