Extensive Variation in Chromatin States Across Humans

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Fast and accurate long-read alignment with Burrows-Wheeler transform.

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A map of human genome variation from population-scale sequencing.

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An integrated map of genetic variation from 1,092 human genomes

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Genetic and epigenetic variation in the lineage specification of regulatory T cells

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The Epigenomic Analysis of Human Obesity

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Genome-Wide Regulatory Adaptation Shapes Population-Level Genomic Landscapes in Heliconius

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Quantitative Genetics of CTCF Binding Reveal Local Sequence Effects and Different Modes of X-Chromosome Association

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Spectacle: fast chromatin state annotation using spectral learning

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DNA methylation in mice is influenced by genetics as well as sex and life experience

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Genetics Driving Epigenetics

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Genome-wide detection of imprinted differentially methylated regions using nanopore sequencing

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Determining causality and consequence of expression quantitative trait loci

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The Genetics of Epigenetic Inheritance: Modes, Molecules, and Mechanisms

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Spatial chromatin architecture alteration by structural variations in human genomes at the population scale

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Nuclear receptors and chromatin: an inducible couple

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De novo mutations in MSL3 cause an X-linked syndrome marked by impaired histone H4 lysine 16 acetylation

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A Glutamatergic Network Mediates Lithium Response in Bipolar Disorder as Defined by Epigenome Pathway Analysis

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Characterizing 5-hydroxymethylcytosine in human prefrontal cortex at single base resolution

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Epigenetic variation impacts individual differences in the transcriptional response to influenza infection

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Histone Modifications and Asthma. The Interface of the Epigenetic and Genetic Landscapes

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Epigenome data release: a participant-centered approach to privacy protection

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Approaches for establishing the function of regulatory genetic variants involved in disease

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Genetic variants alter T-bet binding and gene expression in mucosal inflammatory disease

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Analysis of sensitive information leakage in functional genomics signal profiles through genomic deletions

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Assigning function to SNPs: Considerations when interpreting genetic variation

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Epigenetics and individuality: from concepts to causality across timescales

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The epigenetics of animal personality

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Cell-type-specific brain methylomes profiled via ultralow-input microfluidics

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The methylation landscape and its role in domestication and gene regulation in the chicken

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Chromatin accessibility associates with protein-RNA correlation in human cancer

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Proteomic analysis of hair shafts from monozygotic twins: Expression profiles and genetically variant peptides

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The genetic architecture of DNA replication timing in human pluripotent stem cells

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The pancreatic β cell: recent insights from human genetics

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Regulatory Variants and Disease: The E-Cadherin −160C/A SNP as an Example

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Global variation in gene expression and the value of diverse sampling

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A promoter-proximal transcript targeted by genetic polymorphism controls E-cadherin silencing in human cancers

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Genetic Insights Into Smooth Muscle Cell Contributions to Coronary Artery Disease

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The value of new genome references

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Genetic Variants in Transcription Factor Binding Sites in Humans: Triggered by Natural Selection and Triggers of Diseases

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Epigenomic profiling of primate lymphoblastoid cell lines reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures

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Chromatin modules and their implication in genomic organization and gene regulation

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Role of epigenetics in the development of childhood asthma

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Exploiting genomics and natural genetic variation to decode macrophage enhancers

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Chromatin variation associated with liver metabolism is mediated by transposable elements

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Structure meets function: How chromatin organisation conveys functionality

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Integrative analysis of liver-specific non-coding regulatory SNPs associated with the risk of coronary artery disease

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Promoter-distal RNA polymerase II binding discriminates active from inactive CCAAT/ enhancer-binding protein beta binding sitesPreprint

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BaalChIP: Bayesian analysis of allele-specific transcription factor binding in cancer genomes

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Macrophage Activation: Glancing into Diversity

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GenomeRunner web server: regulatory similarity and differences define the functional impact of SNP sets

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Open Chromatin Profiling in Adipose Tissue Marks Genomic Regions with Functional Roles in Cardiometabolic Traits

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A pooling-based approach to mapping genetic variants associated with DNA methylationPreprint

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A neural network based model effectively predicts enhancers from clinical ATAC-seq samples

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Latexin regulation by HMGB2 is required for hematopoietic stem cell maintenance

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A decomposition-based many-objective artificial bee colony algorithm with reinforcement learning

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Epigenetic biomarkers and preterm birth

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Identification of genetic variants affecting vitamin D receptor binding and associations with autoimmune disease

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Functional effects of variation in transcription factor binding highlight long-range gene regulation by epromoters

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Transcriptional memory in skeletal muscle. Don't forget (to) exercise

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The complex pattern of epigenomic variation between natural yeast strains at single-nucleosome resolution

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Unravelling adverse reactions to NSAIDs using systems biology

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Histone acetylome-wide associations in immune cells from individuals with active Mycobacterium tuberculosis infection

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Different distribution of histone modifications in genes with unidirectional and bidirectional transcription and a role of CTCF and cohesin in directing transcription

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Evidence for a common evolutionary rate in metazoan transcriptional networks

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Sulfasalazine‐Induced Agranulocytosis Is Associated With the Human Leukocyte Antigen Locus

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Allele specific chromatin signals, 3D interactions, and motif predictions for immune and B cell related diseases

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Role of various imbalances centered on alveolar epithelial cell/fibroblast apoptosis imbalance in the pathogenesis of idiopathic pulmonary fibrosis

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Genome-wide methylation and expression analyses reveal the epigenetic landscape of immune-related diseases for tobacco smoking

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Integrative multi-omics analyses to identify the genetic and functional mechanisms underlying ovarian cancer risk regions

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Systematic identification of cis-regulatory variants that cause gene expression differences in a yeast cross

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Functional Characterization of Genetic Variant Effects on Expression

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Recommendations for Accurate Resolution of Gene and Isoform Allele-Specific Expression in RNA-Seq Data

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Synthetic genome readers target clustered binding sites across diverse chromatin states

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CpG binding protein (CFP1) occupies open chromatin regions of active genes, including enhancers and non-CpG islands

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Inherited variants at 3q13.33 and 3p24.1 are associated with risk of diffuse large B-cell lymphoma and implicate immune pathways

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DNA Methylation and Gene Regulation in Honeybees: From Genome-Wide Analyses to Obligatory Epialleles

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Multiomics analysis reveals signatures of selection and loci associated with complex traits in pigs

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Genome Editing in Neurosciences

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Two high-risk susceptibility loci at 6p25.3 and 14q32.13 for Waldenström macroglobulinemia

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Unintended effects of transgenic rice revealed by transcriptome and metabolism

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Conserved regulatory logic at accessible and inaccessible chromatin during the acute inflammatory response in mammals

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Accurate prediction of cis -regulatory modules reveals a prevalent regulatory genome of humans

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DiffChIPL: a differential peak analysis method for high-throughput sequencing data with biological replicates based on limma

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Pseudotime Dynamics in Melanoma Single-Cell Transcriptomes Reveals Different Mechanisms of Tumor Progression

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Extensive epigenetic and transcriptomic variability between genetically identical human B-lymphoblastoid cells with implications in pharmacogenomics research

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Modern human changes in regulatory regions implicated in cortical development

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Understanding three-dimensional chromatin organization in diploid genomes

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Dynamic Chromatin States Coupling with Key Transcription Factors in Colitis‐Associated Colorectal Cancer

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Variation in Vertebrate Cis-Regulatory Elements in Evolution and Disease

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