Student or educator? Sign up with your school email and get 6 months of Pro free.
Cited by 441

The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.

T H 17 Cell Differentiation Is Regulated by the Circadian Clock

Open access
Yu, Xiaofei, Rollins, Darcy, Ruhn, Kelly A., Stubblefield, Jeremy J., Green, Carla B., Kashiwada, Masaki, Rothman, Paul B., Takahashi, Joseph S., Hooper, Lora V.·2013·Science

Abstract

Lighting Up Immunity: T H 17 cells are CD4 + T helper cells that produce the proinflammatory cytokine interleukin-17. In the intestines, T H 17 cells protect the host from fungal and bacterial infections, and their proinflammatory function is linked with autoimmune diseases including inflammatory bowel disease. Yu et al. (p. 727 ) show that the molecular circadian clock directly regulates the differentiation of T H 17 cells in the intestine, which suggest that both nutrition and light are important environmental factors that directly regulate the immune response.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1126/science.1243884

Cites

9 of 9 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 9 references

Cited by

See all 441

Metadata

Authors
Yu, X., Rollins, D., Ruhn, K. A., Stubblefield, J. J., Green, C. B., Kashiwada, M., Rothman, P. B., Takahashi, J. S., & Hooper, L. V.
Venue
Science
Published
2013-11-08
Volume
342
Issue
6159
Pages
727-730
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W1980682199
Cited by
441
References
9
FWCI
15.26
Type
journal article
Language
en
Open access
green

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: T H 17 Cell Differentiation Is Regulated by the Circadian Clock. https://app.cochat.ai/papers/10.1126/science.1243884
The paper
Yu, X., Rollins, D., Ruhn, K. A., Stubblefield, J. J., Green, C. B., Kashiwada, M., Rothman, P. B., Takahashi, J. S., & Hooper, L. V. (2013). T H 17 Cell Differentiation Is Regulated by the Circadian Clock. Science. https://doi.org/10.1126/science.1243884

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.