The Resolution Revolution
Abstract
Advances in detector technology and image processing are yielding high-resolution electron cryo-microscopy structures of biomolecules. [Also see Report by Amunts et al. ]
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The pipeline presented here has been deemed FoldDock and has since been applied.
“The computational cost to run all of this is ~5 days on an Nvidia A100 system and has since the development of the pipeline presented here, deemed FoldDock, been applied37.”
From Improved prediction of protein-protein interactions using AlphaFold2 (2021) · cites this paper as [37]
The computational cost to run all of this is approximately 5 days on an Nvidia A100 system.
“The computational cost to run all of this is ~5 days on an Nvidia A100 system and has since the development of the pipeline presented here, deemed FoldDock, been applied37.”
From Improved prediction of protein-protein interactions using AlphaFold2 (2021) · cites this paper as [37]
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- Authors
- Kühlbrandt, W.
- Affiliations
- Max Planck Institute of Biophysics (DE)
- Corresponding author
- Kühlbrandt, Werner
- ORCID
- Kühlbrandt, Werner
- Venue
- Science
- Published
- 2014-03-28
- Volume
- 343
- Issue
- 6178
- Pages
- 1443-1444
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2051925784
- Cited by
- 1,325
- References
- 10
- Citations by year
- 2026: 120 · 2025: 117 · 2024: 130 · 2023: 110 · 2022: 135 · 2021: 142 · 2020: 121 · 2019: 142 · 2018: 109 · 2017: 73 · 2016: 60 · 2015: 51 · 2014: 15
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Structural Biology › Advanced Electron Microscopy Techniques and Applications
- Physical Sciences › Materials Science › Materials Chemistry › Enzyme Structure and Function
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Structure and Dynamics
- Keywords
- cryo-electron microscopy, high-resolution structure determination, biomolecular structure, detector technology, image processing
- MeSH terms
- Mitochondria, Saccharomyces cerevisiae, Ribosome Subunits, Large, Eukaryotic
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