The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Structure-Guided Transformation of Channelrhodopsin into a Light-Activated Chloride Channel
Open accessAbstract
Optogenetic Insights: Mapping functional neural circuits for many behaviors has been almost impossible, so Vogelstein et al. (p. 386 , published online 27 March; see the Perspective by O'Leary and Marder ) developed a broadly applicable optogenetic method for neuron-behavior mapping and used it to phenotype larval Drosophila and thus developed a reference atlas. As optogenetic experiments become routine in certain fields of neuroscience research, creating even more specialized tools is imperative (see the Perspective by Hayashi ). By engineering channelrhodopsin, Wietek et al. (p. 409 , published online 27 March) and Berndt et al. (p. 420 ) created two different light-gated anion channels to block action potential generation during synaptic stimulation or depolarizing current injections. These new tools not only improve understanding of channelrhodopsins but also provide a way to silence cells.
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Yizhar, O., Fenno, L. E., Prigge, M., Schneider, F., Davidson, T. J., O’Shea, D. J., Sohal, V. S., Goshen, I., Finkelstein, J., Paz, J. T., et al. (2011) · Nature · doi:10.1038/nature10360 · Cited by 2,454
Self-citationThe development and application of optogenetics
Fenno, L., Yizhar, O., & Deisseroth, K. (2011) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-061010-113817 · Cited by 1,822
Self-citationNeural substrates of awakening probed with optogenetic control of hypocretin neurons
Adamantidis, A. R., Zhang, F., Aravanis, A. M., Deisseroth, K., & de Lecea, L. (2007) · Nature · doi:10.1038/nature06310 · Cited by 1,341
Self-citationMattis, J., Tye, K. M., Ferenczi, E. A., Ramakrishnan, C., O'Shea, D. J., Prakash, R., Gunaydin, L. A., Hyun, M., Fenno, L. E., Gradinaru, V., et al. (2012) · Nature Methods · doi:10.1038/nmeth.1808 · Cited by 780
Self-citationOptical control of neuronal excitation and inhibition using a single opsin protein, ChR2
Liske, H., Qian, X., Anikeeva, P., Deisseroth, K., & Delp, S. (2013) · Scientific Reports · doi:10.1038/srep03110 · Cited by 42
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Self-citationIntegration of optogenetics with complementary methodologies in systems neuroscience
Kim, C. K., Adhikari, A., & Deisseroth, K. (2017) · Nature reviews. Neuroscience · doi:10.1038/nrn.2017.15 · Cited by 690
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Self-citationProjections from neocortex mediate top-down control of memory retrieval
Rajasethupathy, P., Sankaran, S., Marshel, J. H., Kim, C. K., Ferenczi, E., Lee, S. Y., Berndt, A., Ramakrishnan, C., Jaffe, A., Lo, M., et al. (2015) · Nature · doi:10.1038/nature15389 · Cited by 509
Self-citationMicrobial Rhodopsins: Diversity, Mechanisms, and Optogenetic Applications
Govorunova, E. G., Sineshchekov, O. A., Li, H., & Spudich, J. L. (2017) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-101910-144233 · Cited by 363
Metadata
- Authors
- Berndt, A., Lee, S. Y., Ramakrishnan, C., & Deisseroth, K.
- Venue
- Science
- Published
- 2014-04-25
- Volume
- 344
- Issue
- 6182
- Pages
- 420-424
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1993257206
- Cited by
- 377
- References
- 5
- FWCI
- 24.15
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
