Chemical Inhibition of NAT10 Corrects Defects of Laminopathic Cells

Larrieu, Delphine, Britton, Sébastien, Demir, Mukerrem, Rodriguez, Raphaël, Jackson, Stephen P.·2014·Science
DOI 10.1126/science.1252651

Cited by (423)

Items 101–200 of 423

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  11. N -acetyltransferase NAT10 controls cell fates via connecting mRNA cytidine acetylation to chromatin signaling
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  16. miR-6716-5p promotes metastasis of colorectal cancer through downregulating NAT10 expression
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  20. Global Profiling of Acetyltransferase Feedback Regulation
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  23. Next-Generation Phenotypic Screening
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  25. Combined loss of LAP1B and LAP1C results in an early onset multisystemic nuclear envelopathy
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  26. Kinesin motor KIFC1 is required for tubulin acetylation and actin-dependent spindle migration in mouse oocyte meiosis
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  27. Metabolic Dysfunction in Hutchinson–Gilford Progeria Syndrome
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  28. Chromosome mis-segregation triggers cell cycle arrest through a mechanosensitive nuclear envelope checkpoint
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  29. Nucleotide resolution sequencing of N4-acetylcytidine in RNA
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  30. NAT10 promotes synovial aggression by increasing the stability and translation of N4-acetylated PTX3 mRNA in rheumatoid arthritis
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  31. Defining the Orphan Functions of Lysine Acetyltransferases
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  32. Remodelin Is a Cryptic Assay Interference Chemotype That Does Not Inhibit NAT10-Dependent Cytidine Acetylation
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  33. NAT10 Promotes Prostate Cancer Growth and Metastasis by Acetylating mRNAs of HMGA1 and KRT8
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  34. The Cytidine N-Acetyltransferase NAT10 Participates in Peripheral Nerve Injury-Induced Neuropathic Pain by Stabilizing SYT9 Expression in Primary Sensory Neurons
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  35. NAT10-mediated RNA acetylation enhances HNRNPUL1 mRNA stability to contribute cervical cancer progression
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  36. Chemotherapy-induced acetylation of ACLY by NAT10 promotes its nuclear accumulation and acetyl-CoA production to drive chemoresistance in hepatocellular carcinoma
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  37. High expression of N-acetyltransferase 10: a novel independent prognostic marker of worse outcome in patients with hepatocellular carcinoma.
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  38. Up regulation of NAT10 promotes metastasis of hepatocellular carcinoma cells through epithelial-to-mesenchymal transition.
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  39. N4-acetylcytidine is required for sustained NLRP3 inflammasome activation via HMGB1 pathway in microglia
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  40. Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia
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  44. Exosomal NAT10 from esophageal squamous cell carcinoma cells modulates macrophage lipid metabolism and polarization through ac4C modification of FASN
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  45. RNA N4‐acetylcytidine modification and its role in health and diseases
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  46. Farnesyltransferase inhibitor and rapamycin correct aberrant genome organisation and decrease DNA damage respectively, in Hutchinson–Gilford progeria syndrome fibroblasts
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  48. Poly(ADP-ribosyl)ation of acetyltransferase NAT10 by PARP1 is required for its nucleoplasmic translocation and function in response to DNA damage
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  49. N-Acetyltransferase 10 represses Uqcr11 and Uqcrb independently of ac4C modification to promote heart regeneration
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  54. SIRT7 is a deacetylase of N4-acetylcytidine on ribosomal RNA
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  55. Chromatin Regulates Genome Targeting with Cisplatin
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  56. DNA Damage Response
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