The DOI matches its Crossref record; 49 of the 49 references it cites were found in a registry or an index.
Polyunsaturated phospholipids facilitate membrane deformation and fission by endocytic proteins
Abstract
Bending the benefits of polyunsaturates: We have often heard that it is beneficial to eat polyunsaturated fatty acids. We also know that some organelles such as synaptic vesicles are extremely rich in polyunsaturated lipids. However, what polyunsaturated lipids do in our body is unclear. Using cell biology, biochemical reconstitutions, and molecular dynamics, Pinot et al. show that polyunsaturated phospholipids can change the response of membranes to proteins involved in membrane curvature sensing, membrane shaping, and membrane fission. Polyunsaturated phospholipids make the plasma membrane more amenable to deformation; facilitate endocytosis; and, in reconstitution experiments, increased membrane fission by the dynamin-endophilin complex. Science , this issue p. 693
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The gut microbiota promotes hepatic fatty acid desaturation and elongation in mice
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Metadata
- Authors
- Pinot, M., Vanni, S., Pagnotta, S., Lacas-Gervais, S., Payet, L.-A., Ferreira, T., Gautier, R., Goud, B., Antonny, B., & Barelli, H.
- Venue
- Science
- Published
- 2014-08-08
- Volume
- 345
- Issue
- 6197
- Pages
- 693-697
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1975794822
- Cited by
- 386
- References
- 49
- FWCI
- 9.61
- Type
- journal article
- Language
- en
- Open access
- closed
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