The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Indole Metabolism in the Pineal Gland: A Circadian Rhythm in N -Acetyltransferase
Abstract
The activity of N -acetyltransferase in the rat pineal gland is more than 15 times higher at night than during the day. This circadian rhythm persists in complete darkness, or in blinded animals, and is suppressed in constant lighting. The N -acetyltransferase rhythm is 180° out of phase with the serotonin rhythm and is similar to the norepinephrine and melatonin rhythms. Experiments in vitro indicate that norepinephrine, not serotonin, regulates the activity of N -acetyltransferase through a highly specific receptor.
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Citations
Cites
The development, topographical relations and innervation of the epiphysis cerebri in the albino rat
Kappers, J. A. (1960) · Zeitschrift f�r Zellforschung und Mikroskopische Anatomie · doi:10.1007/bf00338980 · Cited by 567
Tryptophan Hydroxylation: Measurement in Pineal Gland, Brainstem, and Carcinoid Tumor
Lovenberg, W., Jequier, E., & Sjoerdsma, A. (1967) · Science · doi:10.1126/science.155.3759.217 · Cited by 471
Purification and Properties of Hydroxyindole-O-methyl Transferase
Axelrod, J., & Weissbach, H. (1961) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)64458-8 · Cited by 410
Axelrod, J., Wurtman, R. J., & Snyder, S. H. (1965) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)45266-5 · Cited by 379
Circadian rhythm in rat pineal serotonin and its modifications by estrous cycle and photoperiod
Quay, W. B. (1963) · General and Comparative Endocrinology · doi:10.1016/0016-6480(63)90079-0 · Cited by 360
Biosynthesis of melatonin: enzymic conversion of serotonin to N-acetylserotonin
Weissbach, H., Redfield, B. G., & Axelrod, J. (1960) · Biochimica et Biophysica Acta · doi:10.1016/0006-3002(60)90453-4 · Cited by 262
Circadian and Estrous Rhythms in Pineal Melatonin and 5-Hydroxy Indole-3-Acetic Acid.
Quay, W. B. (1964) · Experimental Biology and Medicine · doi:10.3181/00379727-115-29014 · Cited by 206
CONTROL OF THE CIRCADIAN RHYTHM IN SEROTONIN CONTENT OF THE RAT PINEAL GLAND
Snyder, S. H., ZWEIG, M. H., Axelrod, J., & Fischer, J. E. (1965) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.53.2.301 · Cited by 174
PHOTIC AND NEURAL CONTROL OF THE 24-HOUR NOREPINEPHRINE RHYTHM IN THE RAT PINEAL GLAND
Wurtman, R. J., Axelrod, J., Sedvall, G., & Moore, R. Y. (1967) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)27731-x · Cited by 129
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Cited by
Circadian physiology of metabolism
Panda, S. (2016) · Science · doi:10.1126/science.aah4967 · Cited by 1,092
Simonneaux, V., & Ribelayga, C. (2003) · Pharmacological Reviews · doi:10.1124/pr.55.2.2 · Cited by 740
Tryptophan metabolism in the central nervous system: medical implications
Ruddick, J. P., Evans, A. K., Nutt, D. J., Lightman, S. L., Rook, G. A. W., & Lowry, C. A. (2006) · Expert Reviews in Molecular Medicine · doi:10.1017/s1462399406000068 · Cited by 519
Melatonin directly resets the rat suprachiasmatic circadian clock in vitro
McArthur, A. J., Gillette, M. U., & Prosser, R. A. (1991) · Brain Research · doi:10.1016/0006-8993(91)91748-p · Cited by 314
Metadata
- Authors
- Klein, D. C., & Weller, J. L.
- Venue
- Science
- Published
- 1970-09-11
- Volume
- 169
- Issue
- 3950
- Pages
- 1093-1095
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2003532302
- Cited by
- 746
- References
- 10
- FWCI
- 13.08
- Type
- journal article
- Language
- en
- Open access
- closed
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- Klein, D. C., & Weller, J. L. (1970). Indole Metabolism in the Pineal Gland: A Circadian Rhythm in N -Acetyltransferase. Science. https://doi.org/10.1126/science.169.3950.1093
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
