DPC4 , A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1

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Items 601–700 of 1,002

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10. Differential proteome analysis of conditioned media to detect Smad4 regulated secreted biomarkers in colon cancer
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11. Transforming growth factor-? responsiveness inDPC4/SMAD4-null cancer cells
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18. TGFβ Signaling in the Pancreatic Tumor Microenvironment
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22. Identifying Allelic Loss and Homozygous Deletions in Pancreatic Cancer without Matched Normals Using High-Density Single-Nucleotide Polymorphism Arrays
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26. Clinicopathologic and Immunohistochemical Studies of Papillary Thyroid Microcarcinoma Presenting with Cervical Lymphadenopathy
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30. Context-Dependent Bidirectional Regulation of the MutS Homolog 2 by Transforming Growth Factor β Contributes to Chemoresistance in Breast Cancer Cells
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31. Mutations of the Smad4 gene in acute myelogeneous leukemia and their functional implications in leukemogenesis
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32. Amniotic tissue in complete hydatidiform moles can be androgenetic
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33. Requirement of a specific Sp1 site for histone deacetylase-mediated repression of transforming growth factor beta Type II receptor expression in human pancreatic cancer cells.
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34. Targeted Therapies for Pancreatic Cancer
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35. Decreased Smad4 expression in the transforming growth factor‐β signaling pathway during progression of esophageal squamous cell carcinoma
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36. Somatic alterations of the SMAD-2 gene in human colorectal cancers
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37. Precursor lesions in pancreatic cancer: morphological and molecular pathology
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38. Genetic and Epigenetic Alterations of Familial Pancreatic Cancers
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39. The BHLH transcription factor DEC1 plays an important role in the epithelial-mesenchymal transition of pancreatic cancer
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40. TGF-ßS and Their Roles in the Regulation of Neuron Survival
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41. Smads mediate signaling of the TGFβ superfamily in normal keratinocytes but are lost during skin chemical carcinogenesis
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42. Molecular Aspects of Pancreatic Cancer and Future Perspectives
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43. Analysis of K-ras oncogene mutations in chronic pancreatitis with ductal hyperplasia
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44. Mechanism and Function of Signaling by the TGFβ Superfamily
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45. Prognostic significance of allelic imbalance of chromosome arms 7q, 8p, 16q, and 18q in stage T3N0M0 prostate cancer.
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46. The Synergistic Cooperation between TGF-β and Hypoxia in Cancer and Fibrosis
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47. SMAD Proteins in TGF-β Signalling Pathway in Cancer: Regulatory Mechanisms and Clinical Applications
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48. Transforming Growth Factor β (TGF-β)-Smad Target Gene Protein Tyrosine Phosphatase Receptor Type Kappa Is Required for TGF-β Function
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52. Genetic differences between adenocarcinomas arising in Barrett's esophagus and gastric mucosa
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69. Smad4 Regulates Claudin-1 Expression in a Transforming Growth Factor-β–Independent Manner in Colon Cancer Cells
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70. AGR2 is a SMAD4-suppressible gene that modulates MUC1 levels and promotes the initiation and progression of pancreatic intraepithelial neoplasia
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71. Smad4/DPC4-dependent Regulation of Biglycan Gene Expression by Transforming Growth Factor-β in Pancreatic Tumor Cells
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75. Acinar-to-Ductal Metaplasia Induced by Transforming Growth Factor Beta Facilitates KRAS G12D -driven Pancreatic Tumorigenesis
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79. Genetic Progression of Pancreatic Cancer
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80. Failure Patterns in Resected Pancreas Adenocarcinoma
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83. Tumor suppressor NDRG2 tips the balance of oncogenic TGF-β via EMT inhibition in colorectal cancer
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84. Effector T lymphocyte subsets in human pancreatic cancer: detection of CD8+ CD18+ cells and CD8+ CD103+ cells by multi-epitope imaging
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87. Presence of Two Signaling TGF-β Receptors in Human Pancreatic Cancer Correlates with Advanced Tumor Stage
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89. An Enhancer-Driven Stem Cell–Like Program Mediated by SOX9 Blocks Intestinal Differentiation in Colorectal Cancer
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91. Genetic conditions associated with intestinal juvenile polyps
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92. Role of tumor suppressor genes in the development of adult T cell leukemia/lymphoma (ATLL)
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93. Bone morphogenetic proteins in melanoma: Angel or devil?
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94. Clinical, Molecular and Genetic Validation of a Murine Orthotopic Xenograft Model of Pancreatic Adenocarcinoma Using Fresh Human Specimens
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96. The TGF-β Signalling Network in Muscle Development, Adaptation and Disease
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97. Smad4-independent regulation of p21/WAF1 by transforming growth factor-β
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98. Dominant-Negative Smad2 Mutants Inhibit Activin/Vg1 Signaling and Disrupt Axis Formation in Xenopus
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99. Molecular and functional consequences of Smad4 C-terminal missense mutations in colorectal tumour cells
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100. Transforming growth factor beta signaling is disabled early in human endometrial carcinogenesis concomitant with loss of growth inhibition.
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