The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Control of C. elegans Larval Development by Neuronal Expression of a TGF-β Homolog
Abstract
The Caenorhabditis elegans dauer larva is specialized for dispersal without growth and is formed under conditions of overcrowding and limited food. The daf-7 gene, required for transducing environmental cues that support continuous development with plentiful food, encodes a transforming growth factor-β (TGF-β) superfamily member. A daf-7 reporter construct is expressed in the ASI chemosensory neurons. Dauer-inducing pheromone inhibits daf-7 expression and promotes dauer formation, whereas food reactivates daf-7 expression and promotes recovery from the dauer state. When the food/pheromone ratio is high, the level of daf-7 mRNA peaks during the L1 larval stage, when commitment to non-dauer development is made.
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Citations
Cites
The structure of the nervous system of the nematode Caenorhabditis elegans
White, J. G., Southgate, E., Thomson, J. N., & Brenner, S. (1986) · Philosophical Transactions of the Royal Society of London. B, Biological Sciences · doi:10.1098/rstb.1986.0056 · Cited by 5,589
Cited by
A circuit for navigation in Caenorhabditis elegans
Gray, J. M., Hill, J. J., & Bargmann, C. I. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409009101 · Cited by 811
Two neurons mediate diet-restriction-induced longevity in C. elegans
Bishop, N. A., & Guarente, L. (2007) · Nature · doi:10.1038/nature05904 · Cited by 643
Gottlieb, G. (1998) · Psychological Review · doi:10.1037/0033-295x.105.4.792-802 · Cited by 489
Finch, C. E., & Ruvkun, G. (2001) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.2.1.435 · Cited by 446
The Taxonomy of Developmental Control in Caenorhabditis elegans
Ruvkun, G., & Hobert, O. (1998) · Science · doi:10.1126/science.282.5396.2033 · Cited by 305
Metadata
- Authors
- Ren, P., Lim, C.-S., Johnsen, R., Albert, P. S., Pilgrim, D., & Riddle, D. L.
- Venue
- Science
- Published
- 1996-11-22
- Volume
- 274
- Issue
- 5291
- Pages
- 1389-1391
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2088019468
- Cited by
- 532
- References
- 1
- FWCI
- 5.19
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
