The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Control of C. elegans Larval Development by Neuronal Expression of a TGF-β Homolog
Abstract
The Caenorhabditis elegans dauer larva is specialized for dispersal without growth and is formed under conditions of overcrowding and limited food. The daf-7 gene, required for transducing environmental cues that support continuous development with plentiful food, encodes a transforming growth factor-β (TGF-β) superfamily member. A daf-7 reporter construct is expressed in the ASI chemosensory neurons. Dauer-inducing pheromone inhibits daf-7 expression and promotes dauer formation, whereas food reactivates daf-7 expression and promotes recovery from the dauer state. When the food/pheromone ratio is high, the level of daf-7 mRNA peaks during the L1 larval stage, when commitment to non-dauer development is made.
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Cites
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Two neurons mediate diet-restriction-induced longevity in C. elegans
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The Taxonomy of Developmental Control in Caenorhabditis elegans
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Prohibitin couples diapause signalling to mitochondrial metabolism during ageing in C. elegans
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Maures, T. J., Booth, L. N., Benayoun, B. A., Izrayelit, Y., Schroeder, F. C., & Brunet, A. (2014) · Science · doi:10.1126/science.1244160 · Cited by 165
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Regulation of Chemosensory Receptor Expression and Sensory Signaling by the KIN-29 Ser/Thr Kinase
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TGF-β mimic proteins form an extended gene family in the murine parasite Heligmosomoides polygyrus
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Gene-diet interactions and aging in C. elegans
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Metadata
- Authors
- Ren, P., Lim, C.-S., Johnsen, R., Albert, P. S., Pilgrim, D., & Riddle, D. L.
- Venue
- Science
- Published
- 1996-11-22
- Volume
- 274
- Issue
- 5291
- Pages
- 1389-1391
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2088019468
- Cited by
- 532
- References
- 1
- FWCI
- 5.19
- Type
- journal article
- Language
- en
- Open access
- closed
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