A Mammalian Scaffold Complex That Selectively Mediates MAP Kinase Activation
Cited by (649)
Items 101–200 of 649
- DCX, a new mediator of the JNK pathwayAmos Gdalyahu, Indraneel Ghosh, Talia Levy, Tamar Sapir, Sivan Sapoznik, Yael Fishler, David Azoulai, Orly Reiner · 2004 · The EMBO Journal
- Conceptual Evolution of Cell SignalingArathi Nair, Prashant Singh Chauhan, Bhaskar Saha, Katharina F. Kubatzky · 2019 · International Journal of Molecular Sciences
- KSR is a scaffold required for activation of the ERK/MAPK moduleRoy, François, Laberge, Gino, Douziech, Mélanie, Ferland-McCollough, David, Therrien, Marc · 2002 · Genes & Development
- Identification of the Critical Features of a Small Peptide Inhibitor of JNK ActivityBarr, Renae K., Kendrick, Tulene S., Bogoyevitch, Marie A. · 2002 · Journal of Biological Chemistry
- Kinase Suppressor of Ras Forms a Multiprotein Signaling Complex and Modulates MEK LocalizationScott Stewart, Meera V. Sundaram, Yanping Zhang, Jeeyong Lee, Min Han, Kun‐Liang Guan · 1999 · Molecular and Cellular Biology
- A Network of Mitogen-Activated Protein Kinases Links G Protein-Coupled Receptors to the c- jun Promoter: a Role for c-Jun NH 2 -Terminal Kinase, p38s, and Extracellular Signal-Regulated Kinase 5María Julia Marinissen, Mario Chiariello, Michael Pallante, Jorge Silvio Gutkind · 1999 · Molecular and Cellular Biology
- MyD88-mediated stabilization of interferon-γ-induced cytokine and chemokine mRNADongxu Sun, Aihao H. Ding · 2006 · Nature Immunology
- Akt1 Regulates a JNK Scaffold during Excitotoxic ApoptosisAlbert H. Kim, Hiroko Yano, Han Cho, Debra J. Meyer, Bob R. Monks, Ben L. Margolis, Morris J. Birnbaum, Moses V. Chao · 2002 · Neuron
- Dynamic Complexes of β2-Adrenergic Receptors with Protein Kinases and Phosphatases and the Role of GravinMeiling Shih, Fubao Lin, John D. Scott, Hsien‐yu Wang, Craig C. Malbon · 1999 · Journal of Biological Chemistry
- RACK1, an Insulin-Like Growth Factor I (IGF-I) Receptor-Interacting Protein, Modulates IGF-I-Dependent Integrin Signaling and Promotes Cell Spreading and Contact with Extracellular MatrixUlrich Hermanto, Cong S. Zong, Weiqun Li, Lu‐Hai Wang · 2002 · Molecular and Cellular Biology
- Synergistic activation of SAPK1/JNK1 by two MAP kinase kinases in vitroSean Edward Lawler, Yvonne Fleming, Michel Goedert, Philip Cohen · 1998 · Current Biology
- Strategies for the Selective Regulation of Kinases with Allosteric Modulators: Exploiting Exclusive Structural FeaturesFang, Zhizhou, Grütter, Christian, Rauh, Daniel · 2013 · ACS Chemical Biology
- Interaction of Rac exchange factors Tiam1 and Ras-GRF1 with a scaffold for the p38 mitogen-activated protein kinase cascadeBuchsbaum, Rachel J., Connolly, Beth A., Feig, Larry A. · 2002 · Molecular and Cellular Biology
- Multiple Mitogen-Activated Protein Kinase Signaling Pathways Connect the Cot Oncoprotein to the c- jun Promoter and to Cellular TransformationMario Chiariello, María Julia Marinissen, Jorge Silvio Gutkind · 2000 · Molecular and Cellular Biology
- Dual Roles for c-Jun N-Terminal Kinase in Developmental and Stress Responses in Cerebellar Granule NeuronsEleanor T. Coffey, Vesa Hongisto, Martin Dickens, Roger J. Davis, Michael J. Courtney · 2000 · Journal of Neuroscience
- Cross-talk between JNK/SAPK and ERK/MAPK PathwaysShen, Ying H., Godlewski, Jakub, Zhu, Jun, Sathyanarayana, Pradeep, Leaner, Virna, Birrer, Michael J., Rana, Ajay, Tzivion, Guri · 2003 · Journal of Biological Chemistry
- c-Jun N-Terminal Protein Kinase (JNK) 2/3 Is Specifically Activated by Stress, Mediating c-Jun Activation, in the Presence of Constitutive JNK1 Activity in Cerebellar NeuronsCoffey, Eleanor T., Smiciene, Giedre, Hongisto, Vesa, Cao, Jiong, Brecht, Stephan, Herdegen, Thomas, Courtney, Michael J. · 2002 · The Journal of Neuroscience
- Identification of a new JNK inhibitor targeting the JNK-JIP interaction siteStebbins, John L., De, Surya K., Machleidt, Thomas, Becattini, Barbara, Vazquez, Jesus, Kuntzen, Christian, Chen, Li-Hsing, Cellitti, Jason F., Riel-Mehan, Megan, Emdadi, Aras et al. · 2008 · Proceedings of the National Academy of Sciences
- Regulatory mechanisms of mitogen-activated kinase signalingYueqi Zhang, Chen Dong · 2007 · Cellular and Molecular Life Sciences
- Arsenite-Induced Apoptosis in Cortical Neurons Is Mediated by c-Jun N-Terminal Protein Kinase 3 and p38 Mitogen-Activated Protein KinaseUk Namgung, Zhengui Xia · 2000 · Journal of Neuroscience
- c-Jun N-Terminal Kinase (JNK)-Interacting Protein-1b/Islet-Brain-1 Scaffolds Alzheimer's Amyloid Precursor Protein with JNKShuji Matsuda, Takashi Yasukawa, Yasuko Homma, Yuko Ito, Takako Niikura, Takako Hiraki, Shuichi Hirai, Shigeo Ohno, Yoshiko A. Kita, Masaoki Kawasumi et al. · 2001 · Journal of Neuroscience
- Binding Specificity for RACK1 Resides in the V5 Region of βII Protein Kinase CElizabeth G. Stebbins, Daria Mochly‐Rosen · 2001 · Journal of Biological Chemistry
- The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetesGérard Waeber, Jérôme Delplanque, Christophe Bonny, Vincent Mooser, Myriam Steinmann, Christian Widmann, Anne Manuela Maillard, Judith Miklossy A, Christian Dina C, El Habib Hani et al. · 2000 · Nature Genetics
- HIV-1 Nef increases T cell activation in a stimulus-dependent mannerJeffrey A. Schrager, Jon W. Marsh · 1999 · Proceedings of the National Academy of Sciences
- Roles of Axin in the Wnt Signalling PathwayAkira Kikuchi · 1999 · Cellular Signalling
- A Conserved Docking Site in MEKs Mediates High-affinity Binding to MAP Kinases and Cooperates with a Scaffold Protein to Enhance Signal TransmissionA. Jane Bardwell, Laura J. Flatauer, Karen E. Matsukuma, Jeremy W. Thorner, Lee Bardwell · 2001 · Journal of Biological Chemistry
- The MKK7 Gene Encodes a Group of c-Jun NH 2 -Terminal Kinase KinasesCathy Tournier, Alan J. Whitmarsh, Julie Cavanagh, Tamera Barrett, Roger J. Davis · 1999 · Molecular and Cellular Biology
- MAPK signaling and the kidneyWei Tian, Zheng Zhang, David Cohen · 2000 · American Journal of Physiology-Renal Physiology
- Role of the JIP4 Scaffold Protein in the Regulation of Mitogen-Activated Protein Kinase Signaling PathwaysKelkar, Nyaya, Standen, Claire L., Davis, Roger J. · 2005 · Molecular and Cellular Biology
- APS Facilitates c-Cbl Tyrosine Phosphorylation and GLUT4 Translocation in Response to Insulin in 3T3-L1 AdipocytesJun Liu, Akiko Kimura, Christian A. Baumann, Alan R. Saltiel · 2002 · Molecular and Cellular Biology
- Ganoderma lucidum suppresses angiogenesis through the inhibition of secretion of VEGF and TGF-β1 from prostate cancer cellsGwenaelle Stanley, Kevin A. Harvey, Veronika Slivova, Jiahua Jiang, Daniel Slíva · 2005 · Biochemical and Biophysical Research Communications
- The JIP family of MAPK scaffold proteinsAlan J. Whitmarsh · 2006 · Biochemical Society Transactions
- Rac1 and RhoG promote cell survival by the activation of PI3K and Akt, independently of their ability to stimulate JNK and NF-κBCristina Murga, Muriel Zohar, Hidemi Teramoto, Jorge Silvio Gutkind · 2002 · Oncogene
- Fas/CD95 death receptor and lipid rafts: New targets for apoptosis-directed cancer therapyFaustino Mollinedo, Consuelo Gajate · 2006 · Drug Resistance Updates
- Activated c-Jun N-Terminal Kinase Is Required for Axon FormationAnthony A. Oliva, Coleen M. Atkins, Lily Copenagle, Gary A. Banker · 2006 · Journal of Neuroscience
- MEKK2 Associates with the Adapter Protein Lad/RIBP and Regulates the MEK5-BMK1/ERK5 PathwayWeiyong Sun, Kamala P. Kesavan, Brian C. Schaefer, Timothy P. Garrington, Margaret F. Ware, Nancy Lassignal Johnson, Erwin W. Gelfand, Gary L. Johnson · 2001 · Journal of Biological Chemistry
- Jun NH2-terminal Kinase (JNK) Interacting Protein 1 (JIP1) Binds the Cytoplasmic Domain of the Alzheimer's β-Amyloid Precursor Protein (APP)Meir H. Scheinfeld, Roberta Roncarati, Pasquale Vito, Peter Lopez, Mona Abdallah, Luciano D'adamio · 2002 · Journal of Biological Chemistry
- A Scaffold Protein JIP-1b Enhances Amyloid Precursor Protein Phosphorylation by JNK and Its Association with Kinesin Light Chain 1Hidehiko Inomata, Yoshitaka Nakamura, Akira Hayakawa, Hiroyuki Takata, Toshiharu Suzuki, Keiji Miyazawa, Naomi Kitamura · 2003 · Journal of Biological Chemistry
- c-Jun NH 2 -Terminal Kinase Is Essential for the Regulation of AP-1 by Tumor Necrosis FactorJuan‐José Ventura, Norman J. Kennedy, Jennifer A. Lamb, Richard Anthony Flavell, Roger J. Davis · 2003 · Molecular and Cellular Biology
- Protein Tyrosine Phosphorylation and Protein Tyrosine Nitration in Redox SignalingHugo P. Monteiro, Roberto Jun Arai, Luiz Rodolpho Travassos · 2008 · Antioxidants and Redox Signaling
- Phosphorylated Tau Interacts with c-Jun N-terminal Kinase-interacting Protein 1 (JIP1) in Alzheimer DiseaseLars Matthias Ittner, Yazi Diana Ke, Jürgen Götz · 2009 · Journal of Biological Chemistry
- Differential activation of p38MAPK isoforms by MKK6 and MKK3Gaëlle Rémy, Ana M. Risco, Francisco Iñesta-Vaquera, Bárbara González‐Terán, Guadalupe Sabio, Roger J. Davis, Ana Cuenda · 2009 · Cellular Signalling
- Conserved Docking Site Is Essential for Activation of Mammalian MAP Kinase Kinases by Specific MAP Kinase Kinase KinasesMutsuhiro Takekawa, Kazuo Tatebayashi, Haruo Saito · 2005 · Molecular Cell
- Functions of lipoprotein receptors in neuronsUwe Beffert, Peggy C. Stolt-Bergner, Joachim Herz · 2004 · Journal of Lipid Research
- Arabidopsis kinome: after the castingAntony Champion, Martin E. Kreis, Keithanne Mockaitis, Alain Picaud, Y. Henry · 2004 · Functional & Integrative Genomics
- JNK: a new therapeutic target for diabetesBrydon L. Bennett · 2003 · Current Opinion in Pharmacology
- Calcium-dependent membrane association sensitizes soluble guanylyl cyclase to nitric oxideUlrike Zabel, Christoph Kleinschnitz, Phil Oh, Pavel I. Nedvetsky, Albert Smolenski, Helmut Müller, Petra Kronich, P. Kügler, Ulrich Walter, Jan E. Schnitzer et al. · 2002 · Nature Cell Biology
- The bottleneck of JNK signaling: Molecular and functional characteristics of MKK4 and MKK7Wiebke Haeusgen, Thomas Herdegen, Vicki Waetzig · 2011 · European Journal of Cell Biology
- Silymarin inhibits growth and causes regression of established skin tumors in SENCAR mice via modulation of mitogen-activated protein kinases and induction of apoptosisRana Pratap Singh, Anil K. Tyagi, Jifu Zhao, Rajesh Agarwal · 2002 · Carcinogenesis
- OMTK1, a Novel MAPKKK, Channels Oxidative Stress Signaling through Direct MAPK InteractionHirofumi Nakagami, Stefan Kiegerl, Heribert Hirt A · 2004 · Journal of Biological Chemistry
- The Cyclin D1 Gene Is Transcriptionally Repressed by Caveolin-1James Hulit, Tal Bash, Maofu Fu, Ferruccio Galbiati, Chris Albanese, Daniel Sage, Amnon Schlegel, Jacob Zhurinsky, Michael S. Shtutman, Avri Ben‐Ze'ev et al. · 2000 · Journal of Biological Chemistry
- Identification of a Motif in the Carboxyl Terminus of β-Arrestin2 Responsible for Activation of JNK3William E. Miller, Patricia H. McDonald, Sheng F. Cai, Michael E. Field, Roger J. Davis, Robert J. Lefkowitz · 2001 · Journal of Biological Chemistry
- The Molecular Scaffold KSR1 Regulates the Proliferative and Oncogenic Potential of CellsRobert L. Kortum, Robert E. Lewis · 2004 · Molecular and Cellular Biology
- The true face of JNK activation in apoptosisAnning Lin, Benjamin C. Dibling · 2002 · Aging Cell
- c-Jun NH 2 -Terminal Kinase Inhibits Targeting of the Protein Phosphatase Calcineurin to NFATc1Chi-Wing Chow, Chen Dong, Richard Anthony Flavell, Roger J. Davis · 2000 · Molecular and Cellular Biology
- Role of the Ubiquitin Proteasome System in the HeartJulia K. Pagan, Tiffany Seto, Michele Pagano, Antonio Cittadini · 2013 · Circulation Research
- Activation of cJUN N-Terminal Kinase by Herpes Simplex Virus Type 1 Enhances Viral ReplicationTim I. McLean, Steven L. Bachenheimer · 1999 · Journal of Virology
- Ki-ras and the Characteristics of Mouse Lung TumorsGayatri Ramakrishna, Aneta Bialkowska, Christine M. Perella, Lisa Birely, Laura W. Fornwald, Bhalchandra A. Diwan, Yih‐Horng Shiao, Lucy M. Anderson · 2000 · Molecular Carcinogenesis
- Regulatory mechanisms and functions of MAP kinase signaling pathwaysMasamichi Imajo, Yoshiki Tsuchiya, Eisuke Nishida · 2006 · IUBMB Life
- Fibroblast growth factor homologous factors are intracellular signaling proteins.Jon Schoorlemmer, M. Goldfarb · 2001 · Current Biology
- Mechanisms of action of novel agents for prostate cancer chemopreventionRana Pratap Singh, Rajesh Agarwal · 2006 · Endocrine Related Cancer
- Prostate Cancer Prevention by SilibininRana Pratap Singh, Rajesh Agarwal · 2004 · Current Cancer Drug Targets
- The Annexin Protein Lipocortin 1 Regulates the MAPK/ERK PathwayLouise C. Alldridge, Hayley J. Harris, Robin J. Plevin, Robert Hannon, Clare Elizabeth Bryant · 1999 · Journal of Biological Chemistry
- Localization and trafficking of α2-adrenergic receptor subtypes in cells and tissuesChristine Saunders · 1999 · Pharmacology & Therapeutics
- Routing MAP Kinase CascadesElaine A. Elion · 1998 · Science
- The bright side of JNKs—Multitalented mediators in neuronal sprouting, brain development and nerve fiber regenerationVicki Waetzig, Yi Zhao, Thomas Herdegen · 2006 · Progress in Neurobiology
- Contribution of the ERK5/MEK5 Pathway to Ras/Raf Signaling and Growth ControlJessie M. English, Gray W. Pearson, Tish Hockenberry, Latha Shivakumar, Michael A. White, Melanie H. Cobb · 1999 · Journal of Biological Chemistry
- Targeting JNK3 for the treatment of neurodegenerative disordersLynn Resnick, Myles Fennell · 2004 · Drug Discovery Today
- Interaction of Alzheimer's β-Amyloid Precursor Family Proteins with Scaffold Proteins of the JNK Signaling CascadeHidenori Taru, Koichi Iijima, Momoko Hase, Yutaka Kirino, Yoshimasa Yagi, Toshiharu Suzuki · 2002 · Journal of Biological Chemistry
- 'Location, location, location': activation and targeting of MAP kinases by G protein-coupled receptorsLouis M. Luttrell · 2003 · Journal of Molecular Endocrinology
- The NF-κB Repressing Factor Is Involved in Basal Repression and Interleukin (IL)-1-induced Activation of IL-8 Transcription by Binding to a Conserved NF-κB-flanking Sequence ElementMahtab Nourbakhsh, Solveig Kälble, Anneke Dörrie, H. Häuser, Klaus Resch, Michael Kracht · 2001 · Journal of Biological Chemistry
- The Evolution of the MAP Kinase Pathways: Coduplication of Interacting Proteins Leads to New Signaling CascadesCaffrey, Daniel R., O'Neill, Luke A.J., Shields, Denis C. · 1999 · Journal of Molecular Evolution
- Interaction of c-Jun amino-terminal kinase interacting protein-1 with p190 rhoGEF and its localization in differentiated neuronsMeyer, Debra, Liu, Albert, Margolis, Ben · 1999 · Journal of Biological Chemistry
- The Role of Specific Mitogen-Activated Protein Kinase Signaling Cascades in the Regulation of SteroidogenesisPulak R. Manna, Douglas M. Stocco · 2011 · Journal of Signal Transduction
- Mitogen-activated Protein Kinase Phosphatase-1 (MKP-1) Expression Is Induced by Low Oxygen Conditions Found in Solid Tumor MicroenvironmentsKeith R. Laderoute, Holly L. Mendonca, Joy M. Calaoagan, A. Merrill Knapp, Amato J. Giaccia, Philip A. Stork · 1999 · Journal of Biological Chemistry
- Regulation of MAP kinases by docking domainsHervé Enslen, Roger J. Davis · 2001 · Biology of the Cell
- The phosphatidylinositol 3-kinase/Akt and c-Jun N-terminal kinase signaling in cancer: Alliance or contradiction? (Review)Hua Zhao, Jing Wang, Shing Shun Tony To · 2015 · International Journal of Oncology
- IB1 Reduces Cytokine-induced Apoptosis of Insulin-secreting CellsChristophe Bonny, Anne Oberson, Myriam Steinmann, Daniel F. Schorderet, PASCAL H. NICOD, Gérard Waeber · 2000 · Journal of Biological Chemistry
- An essential role of the JIP1 scaffold protein for JNK activation in adipose tissueJaeschke, Anja, Czech, Michael P., Davis, Roger J. · 2004 · Genes & Development
- C-Jun NH(2)-terminal kinase mediates proliferation and tumor growth of human prostate carcinoma.Yong-Min Yang, Frédéric Bost, Wilfried Charbono, Nicholas S. Dean, Robert A. McKay, Johng Sik Rhim, Chantal Depatie, Dan Mercola · 2003 · PubMed
- Neuroprotection against ischaemic brain injury by a GluR6-9c peptide containing the TAT protein transduction sequenceDong-Sheng Pei, Xiao-Tian Wang, Yong U. Liu, Ya‐Feng Sun, Qiu‐Hua Guan, Wei Wang, Jing-Zhi Yan, Yan‐Yan Zong, Tian‐Le Xu, Guangyi Zhang · 2005 · Brain
- Neuroprotective Effect of Eicosapentaenoic Acid in Hippocampus of Rats Exposed to γ-IrradiationPeter Eoin Lonergan, Darren S.D. Martin, David F. Horrobin, Marina A. Lynch · 2002 · Journal of Biological Chemistry
- Role of scaffolds in MAP kinase pathway specificity revealed by custom design of pathway-dedicated signaling proteinsKendra K. Harris, Rachel E. Lamson, Bryce Nelson, Timothy R. Hughes, Matthew John Marton, Christopher J. Roberts, Charles M. Boone, Peter M. Pryciak · 2001 · Current Biology
- MEKK1 Binds Raf-1 and the ERK2 Cascade ComponentsMahesh S. Karandikar, Shuichan Xu, Melanie H. Cobb · 2000 · Journal of Biological Chemistry
- βArrestinsPatricia H. McDonald, Robert J. Lefkowitz · 2001 · Cellular Signalling
- A Docking Site in MKK4 Mediates High Affinity Binding to JNK MAPKs and Competes with Similar Docking Sites in JNK SubstratesHo, David T., Bardwell, A.Jane, Abdollahi, Mahsa, Bardwell, Lee · 2003 · Journal of Biological Chemistry
- Fibroblast Growth Factor Homologous Factors and the Islet Brain-2 Scaffold Protein Regulate Activation of a Stress-activated Protein Kinase*Jon Schoorlemmer, M. Goldfarb · 2002 · Journal of Biological Chemistry
- Estrogen, mitochondria, and growth of cancer and non-cancer cells.Quentin H. Felty, Deodutta Roy · 2005 · Journal of Carcinogenesis
- Coordinated transport of phosphorylated amyloid-β precursor protein and c-Jun NH2-terminal kinase–interacting protein-1Zoia Ladescu Muresan, Virgil Mureşan · 2005 · The Journal of Cell Biology
- Signaling Complexes: Junctions on the Intracellular Information Super HighwayF.Donelson Smith, John D. Scott · 2002 · Current Biology
- Inhibition of JNK by Overexpression of the JNK Binding Domain of JIP-1 Prevents Apoptosis in Sympathetic NeuronsHarding, Thomas C., Xue, Luzheng, Bienemann, Ali, Haywood, Darren, Dickens, Martin, Tolkovsky, Aviva M., Uney, James B. · 2001 · Journal of Biological Chemistry
- An Inhibitor of p38 and JNK MAP Kinases Prevents Activation of Caspase and Apoptosis of Cultured Cerebellar Granule NeuronsHarada Jun, Masahiko Sugimoto · 1999 · The Japanese Journal of Pharmacology
- Tea polyphenols and their chemopreventive and therapeutic effects on colorectal cancerShi-Tong Wang, Wenqi Cui, Dan Pan, Min Jiang, Bing Chang, Li-Xuan Sang · 2020 · World Journal of Gastroenterology
- Robust Stability of the Embryonic Axial Pattern Requires a Secreted Scaffold for Chordin DegradationHidehiko Inomata, Tomoko Haraguchi, Yoshiki Sasai · 2008 · Cell
- Cross Talk of Signaling Pathways in the Regulation of the Glucocorticoid Receptor FunctionLaura Davies, Nirupama Karthikeyan, James T. Lynch, Elin-Alia Sial, Areti Gkourtsa, Constantinos Demonacos, Marija Krstic–Demonacos · 2008 · Molecular Endocrinology
- The JNK-interacting Protein-1 Scaffold Protein Targets MAPK Phosphatase-7 to Dephosphorylate JNKEmma A. Willoughby, Gordon R. Perkins, Mary K. Collins, Alan J. Whitmarsh · 2003 · Journal of Biological Chemistry
- Modular construction of a signaling scaffold: MORG1 interacts with components of the ERK cascade and links ERK signaling to specific agonistsTomáš Vomastek, H. J. Schaeffer, Adel Tarcsafalvi, Mark E. Smolkin, Eric A. Bissonette, Michael J. Weber · 2004 · Proceedings of the National Academy of Sciences
- Mixed lineage kinase‐dependent JNK activation is governed by interactions of scaffold protein JIP with MAPK module componentsDeepak Nihalani, Debra Meyer, Sangeeta Pajni, Lawrence B. Holzman · 2001 · The EMBO Journal
- Kinases as therapeutic targets for heart failureChris J. Vlahos, Susan A. McDowell, Angela Clerk · 2003 · Nature Reviews Drug Discovery
- The Role of the Dysregulated JNK Signaling Pathway in the Pathogenesis of Human Diseases and Its Potential Therapeutic Strategies: A Comprehensive ReviewHuaying Yan, Lanfang He, De Lv, Jun Yang, Zhu Yuan · 2024 · Biomolecules