The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Somatostatin Augments the M-Current in Hippocampal Neurons
Abstract
Immunocytochemical and electrophysiological evidence suggests that somatostatin may be a transmitter in the hippocampus. To characterize the ionic mechanisms underlying somatostatin effects, voltage-clamp and current-clamp studies on single CA1 pyramidal neurons in the hippocampal slice preparation were performed. Both somatostatin-28 and somatostatin-14 elicited a steady outward current and selectively augmented the noninactivating, voltage-dependent outward potassium current known as the M-current. Since the muscarinic cholinergic agonists carbachol and muscarine antagonized this current, these results suggest a reciprocal regulation of the M-current by somatostatin and acetylcholine.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The cholinergic hypothesis of geriatric memory dysfunction
Bartus, R. T., Dean, R. L., Beer, B., & Lippa, A. S. (1982) · Science · doi:10.1126/science.7046051 · Cited by 5,545
Davies, P., Katzman, R., & Terry, R. D. (1980) · Nature · doi:10.1038/288279a0 · Cited by 882
Tsunoo, A., Yoshii, M., & Narahashi, T. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.24.9832 · Cited by 218
Cited by
Cellular and molecular mechanisms of drug dependence
Koob, G. F., & Bloom, F. E. (1988) · Science · doi:10.1126/science.2903550 · Cited by 2,070
Chapter 12 Potassium currents in hippocampal pyramidal cells
Storm, J. F. (1990) · Progress in Brain Research · doi:10.1016/s0079-6123(08)61248-0 · Cited by 743
Pathways modulating neural KCNQ/M (Kv7) potassium channels
Delmas, P., & Brown, D. A. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1785 · Cited by 686
Hashimoto, T., Arion, D., Unger, T., Maldonado-Avilés, J. G., Morris, H. M., Volk, D. W., Mirnics, K., & Lewis, D. A. (2008) · Molecular Psychiatry · doi:10.1038/sj.mp.4002011 · Cited by 490
A cortical neuropeptide with neuronal depressant and sleep-modulating properties
de Lecea, L., Criado, J. R., Prospero-Garcia, Ó., Gautvik, K. M., Schweitzer, P., Danielson, P. E., Dunlop, C. L. M., Siggins, G. R., Henriksen, S. J., & Sutcliffe, J. G. (1996) · Nature · doi:10.1038/381242a0 · Cited by 416
Self-citation
Metadata
- Authors
- Moore, S. D., Madamba, S. G., Joëls, M., & Siggins, G. R.
- Venue
- Science
- Published
- 1988-01-15
- Volume
- 239
- Issue
- 4837
- Pages
- 278-280
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2063109997
- Cited by
- 214
- References
- 3
- FWCI
- 6.73
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Somatostatin Augments the M-Current in Hippocampal Neurons. https://app.cochat.ai/papers/10.1126/science.2892268
- The paper
- Moore, S. D., Madamba, S. G., Joëls, M., & Siggins, G. R. (1988). Somatostatin Augments the M-Current in Hippocampal Neurons. Science. https://doi.org/10.1126/science.2892268
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
