The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
Transgene and Transposon Silencing in Chlamydomonas reinhardtii by a DEAH-Box RNA Helicase
Abstract
The molecular mechanism(s) responsible for posttranscriptional gene silencing and RNA interference remain poorly understood. We have cloned a gene ( Mut6 ) from the unicellular green alga Chlamydomonas reinhardtii that is required for the silencing of a transgene and two transposon families. Mut6 encodes a protein that is highly homologous to RNA helicases of the DEAH-box family. This protein is necessary for the degradation of certain aberrant RNAs, such as improperly processed transcripts, which are often produced by transposons and some transgenes.
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Cites
A Species of Small Antisense RNA in Posttranscriptional Gene Silencing in Plants
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An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
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The rde-1 Gene, RNA Interference, and Transposon Silencing in C. elegans
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hnRNP complexes: composition, structure, and function
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Cited by
Asymmetry in the Assembly of the RNAi Enzyme Complex
Schwarz, D. S., Hutvágner, G., Du, T., Xu, Z., Aronin, N., & Zamore, P. D. (2003) · Cell · doi:10.1016/s0092-8674(03)00759-1 · Cited by 2,922
Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs
Meister, G., Landthaler, M., Patkaniowska, A., Dorsett, Y., Teng, G., & Tuschl, T. (2004) · Molecular Cell · doi:10.1016/j.molcel.2004.07.007 · Cited by 2,052
Ketting, R. F., Fischer, S. E. J., Bernstein, E., Sijen, T., Hannon, G. J., & Plasterk, R. H. A. (2001) · Genes & Development · doi:10.1101/gad.927801 · Cited by 1,852
Argonaute2, a Link Between Genetic and Biochemical Analyses of RNAi
Hammond, S. M., Boettcher, S., Caudy, A. A., Kobayashi, R., & Hannon, G. J. (2001) · Science · doi:10.1126/science.1064023 · Cited by 1,580
RNA Interference: Biology, Mechanism, and Applications
Agrawal, N., Dasaradhi, P. V. N., Mohmmed, A., Malhotra, P., Bhatnagar, R. K., & Mukherjee, S. K. (2003) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.67.4.657-685.2003 · Cited by 1,305
Metadata
- Authors
- Wu-Scharf, D., Jeong, B.-R., Zhang, C., & Cerutti, H.
- Venue
- Science
- Published
- 2000-11-10
- Volume
- 290
- Issue
- 5494
- Pages
- 1159-1162
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1602141296
- Cited by
- 280
- References
- 25
- FWCI
- 11.94
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Transgene and Transposon Silencing in Chlamydomonas reinhardtii by a DEAH-Box RNA Helicase. https://app.cochat.ai/papers/10.1126/science.290.5494.1159
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- Wu-Scharf, D., Jeong, B.-R., Zhang, C., & Cerutti, H. (2000). Transgene and Transposon Silencing in Chlamydomonas reinhardtii by a DEAH-Box RNA Helicase. Science. https://doi.org/10.1126/science.290.5494.1159
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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