The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Antibodies Reactive with Human T-Lymphotropic Retroviruses (HTLV-III) in the Serum of Patients with AIDS
Abstract
In cats, infection with T-lymphotropic retroviruses can cause T-cell proliferation and leukemia or T-cell depletion and immunosuppression. In humans, some highly T4 tropic retroviruses called HTLV-I can cause T-cell proliferation and leukemia. The subgroup HTLV-II also induces T-cell proliferation in vitro, but its role in disease is unclear. Viruses of a third subgroup of human T-lymphotropic retroviruses, collectively designated HTLV-III, have been isolated from cultured cells of 48 patients with acquired immunodeficiency syndrome (AIDS). The biological properties of HTLV-III and immunological analyses of its proteins show that this virus is a member of the HTLV family, and that it is more closely related to HTLV-II than to HTLV-I. Serum samples from 88 percent of patients with AIDS and from 79 percent of homosexual men with signs and symptoms that frequently precede AIDS, but from less than 1 percent of heterosexual subjects, have antibodies reactive against antigens of HTLV-III. The major immune reactivity appears to be directed against p41, the presumed envelope antigen of the virus.
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Cited by
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Self-citationpH-independent HIV entry into CD4-positive T cells via virus envelope fusion to the plasma membrane
Stein, B. S., Gowda, S. D., Lifson, J. D., Penhallow, R. C., Bensch, K. G., & Engleman, E. G. (1987) · Cell · doi:10.1016/0092-8674(87)90542-3 · Cited by 627
Fine structure of human immunodeficiency virus (HIV) and immunolocalization of structural proteins
Gelderblom, H. R., Hausmann, E. H. S., Özel, M., Pauli, G., & Koch, M. A. (1987) · Virology · doi:10.1016/0042-6822(87)90449-1 · Cited by 521
AIDS Retrovirus Induced Cytopathology: Giant Cell Formation and Involvement of CD4 antigen
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Historical review of the causes of cancer
Blackadar, C. B. (2016) · World Journal of Clinical Oncology · doi:10.5306/wjco.v7.i1.54 · Cited by 389
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Primary Human T-Lymphotropic Virus Type III Infection
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Biochemical and immunological analysis of human immunodeficiency virus gag gene products p17 and p24
Veronese, F. D., Copeland, T. D., Oroszlan, S., Gallo, R. C., & Sarngadharan, M. G. (1988) · Journal of Virology · doi:10.1128/jvi.62.3.795-801.1988 · Cited by 203
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Metadata
- Authors
- Sarngadharan, M. G., Popovic, M., Bruch, L., Schüpbach, J., & Gallo, R. C.
- Venue
- Science
- Published
- 1984-05-04
- Volume
- 224
- Issue
- 4648
- Pages
- 506-508
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2043015697
- Cited by
- 1,148
- References
- 1
- FWCI
- 92.71
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
