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Cited by 191

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Corticotropin-Releasing Factor Receptors in Rat Forebrain: Autoradiographic Identification

De Souza, Errol B., Perrin, Marilyn H., Insel, Thomas R., Rivier, Jean, Vale, Wylie W., Kuhar, Michael J.·1984·Science

Abstract

Corticotropin-releasing factor (CRF) receptors were identified in rat forebrain by autoradiography with an iodine-125-labeled analog of ovine CRF substituted with norleucine and tyrosine at amino acid residues 21 and 32, respectively. High-affinity receptors for CRF were found in discrete areas of rat forebrain, including laminae I and IV of the neocortex, the external layer of the median eminence, the lateral nucleus of the amygdala, and the striatum. These results are consistent with earlier findings on the immunohistochemical distribution of CRF and suggest that endogenous CRF has a physiological role in regulating activity of the central nervous system.

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Metadata

Authors
De Souza, E. B., Perrin, M. H., Insel, T. R., Rivier, J., Vale, W. W., & Kuhar, M. J.
Venue
Science
Published
1984-06-29
Volume
224
Issue
4656
Pages
1449-1451
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2045729297
Cited by
191
References
5
FWCI
6.12
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Corticotropin-Releasing Factor Receptors in Rat Forebrain: Autoradiographic Identification. https://app.cochat.ai/papers/10.1126/science.6328656
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De Souza, E. B., Perrin, M. H., Insel, T. R., Rivier, J., Vale, W. W., & Kuhar, M. J. (1984). Corticotropin-Releasing Factor Receptors in Rat Forebrain: Autoradiographic Identification. Science. https://doi.org/10.1126/science.6328656

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