The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
A Simple Genetic Basis for a Complex Psychological Trait in Laboratory Mice
Abstract
Psychological traits are commonly inferred from covariation in sets of behavioral measures that otherwise appear to have little in common. Emotionality in mice is such a trait, defined here by covariation in activity and defecation in a novel environment and emergence into the open arms of an elevated plus maze. Behavioral and quantitative trait analyses were conducted on four measures obtained from 879 mice from an F 2 intercross. Three loci, on murine chromosomes 1, 12, and 15, were mapped that influence emotionality. This trait, inferred from studies of strain, sex, and individual differences in rodents, may be related to human susceptibility to anxiety or neuroticism.
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Citations
Cites
Toward a general psychobiological theory of emotions
Panksepp, J. (1982) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00012759 · Cited by 999
Cited by
Lesch, K.-P., Bengel, D., Heils, A., Sabol, S. Z., Greenberg, B. D., Petri, S., Benjamin, J., Müller, C. R., Hamer, D. H., & Murphy, D. L. (1996) · Science · doi:10.1126/science.274.5292.1527 · Cited by 5,162
Genetics of Mouse Behavior: Interactions with Laboratory Environment
Crabbe, J. C., Wahlsten, D., & Dudek, B. C. (1999) · Science · doi:10.1126/science.284.5420.1670 · Cited by 1,666
The Genetic Architecture of Quantitative Traits
Mackay, T. F. C. (2001) · Annual Review of Genetics · doi:10.1146/annurev.genet.35.102401.090633 · Cited by 1,106
Genes, evolution, and personality
Bouchard, T. J., & Loehlin, J. C. (2001) · Behavior Genetics · doi:10.1023/a:1012294324713 · Cited by 1,085
Habituation in rodents: a review of behavior, neurobiology, and genetics
LEUSSIS, M., & BOLIVAR, V (2006) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2006.03.006 · Cited by 330
What's wrong with my mouse model?
Kalueff, A. V., Wheaton, M., & Murphy, D. L. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.01.023 · Cited by 285
Cui, C., Booker, T. K., Allen, R. S., Grady, S. R., Whiteaker, P., Marks, M. J., Salminen, O., Tritto, T., Butt, C. M., Allen, W. R., et al. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-35-11045.2003 · Cited by 213
Self-citationBehavior and mutagenesis screens: The importance of baseline analysis of inbred strains
Tarantino, L. M., Gould, T. J., Druhan, J. P., & Bucan, M. (2000) · Mammalian Genome · doi:10.1007/s003350010107 · Cited by 158
Selection for contextual fear conditioning affects anxiety‐like behaviors and gene expression
Ponder, C. A., Kliethermes, C. L., Drew, M. R., Muller, J., Das, K., Risbrough, V. B., Crabbe, J. C., Gilliam, T. C., & Palmer, A. A. (2007) · Genes, Brain and Behavior · doi:10.1111/j.1601-183x.2007.00306.x · Cited by 95
Baeza-Raja, B., Eckel-Mahan, K., Zhang, L., Vagena, E., Tsigelny, I. F., Sassone-Corsi, P., Ptacek, L. J., & Akassoglou, K. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.2757-12.2013 · Cited by 44
Thifault, S., Lalonde, R., Sanon, N., & Hamet, P. (2002) · Brain Research Bulletin · doi:10.1016/s0361-9230(02)00782-7 · Cited by 29
Selective Breeding for an Infantile Phenotype (Isolation Calling)
Brunelli, S. A., & Hofer, M. A. (2001) · Handbook of Behavioral Neurobiology · doi:10.1007/978-1-4615-1209-7_12 · Cited by 9
Metadata
- Authors
- Flint, J., Corley, R., DeFries, J. C., Fulker, D. W., Gray, J. A., Miller, S., & Collins, A. C.
- Venue
- Science
- Published
- 1995-09-08
- Volume
- 269
- Issue
- 5229
- Pages
- 1432-1435
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2016572676
- Cited by
- 438
- References
- 1
- FWCI
- 14.80
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
